Abbasloo E, Khaksari M, Sanjari M et al (2023) Carvacrol decreases blood–brain barrier permeability post-diffuse traumatic brain injury in rats. Sci Rep 13(1):14546. https://doi.org/10.1038/s41598-023-40915-x

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ahluwalia M, Kumar M, Ahluwalia P et al (2021) Rescuing mitochondria in traumatic brain injury and intracerebral hemorrhages-a potential therapeutic approach. Neurochem Int. https://doi.org/10.1016/j.neuint.2021.105192

Article  PubMed  PubMed Central  Google Scholar 

Almeida-Suhett CP, Prager EM, Pidoplichko V et al (2014) Reduced GABAergic inhibition in the basolateral amygdala and the development of anxiety-like behaviors after mild traumatic brain injury. PLoS ONE 9(7):e102627. https://doi.org/10.1371/journal.pone.0102627

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bagri K, Deshmukh R (2022) Vinpocetine restores cognitive and motor functions in traumatic brain injury challenged rats. Inflammopharmacol 30:2243–2259. https://doi.org/10.1007/s10787-022-01059-y

Article  CAS  Google Scholar 

Banderwal R, Kadian M, Garg S et al (2024) Comprehensive review of emerging drug targets in traumatic brain injury (TBI): challenges and future scope. Inflammopharmacol 32(5):3271–3293. https://doi.org/10.1007/s10787-024-01524-w

Article  Google Scholar 

Barot J, Saxena B (2021) Therapeutic effects of eugenol in a rat model of traumatic brain injury: a behavioral, biochemical, and histological study. J Tradit Complement Med 11(4):318–327. https://doi.org/10.1016/j.jtcme.2021.01.003

Article  CAS  PubMed  PubMed Central  Google Scholar 

Broglio SP, Puetz TW (2008) The effect of sport concussion on neurocognitive function, self-report symptoms and postural control: a meta-analysis. Sports Med 38(1):53–67. https://doi.org/10.2165/00007256-200838010-00005

Article  PubMed  Google Scholar 

Brown MR, Sullivan PG, Dorenbos KA et al (2004) Nitrogen disruption of synaptoneurosomes: an alternative method to isolate brain mitochondria. J Neurosci Methods 137(2):299–303

Article  CAS  PubMed  Google Scholar 

Carinci M, Vezzani B, Patergnani S et al (2021) Different roles of mitochondria in cell death and inflammation: focusing on mitochondrial quality control in ischemic stroke and reperfusion. Biomedicines 9(2):169. https://doi.org/10.3390/biomedicines9020169

Article  CAS  PubMed  PubMed Central  Google Scholar 

Charrueau C, Belabed L, Besson V et al (2009) Metabolic response and nutritional support in traumatic brain injury: evidence for resistance to renutrition. J Neurotrauma 26(11):1911–1920. https://doi.org/10.1089/neu.2008.0737

Article  PubMed  Google Scholar 

Chen W, Guo C, Jia Z (2020) Inhibition of mitochondrial ROS by MitoQ alleviates white matter injury and improves outcomes after intracerebral haemorrhage in mice. Oxid Med Cell Longev 1:8285065. https://doi.org/10.1155/2020/8285065

Article  CAS  Google Scholar 

Chodobski A, Zink BJ, Szmydynger-Chodobska J (2011) Blood–brain barrier pathophysiology in traumatic brain injury. Transl Stroke Res 2(4):492–516

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ding W, Cai C, Zhu X et al (2022) Parthenolide ameliorates neurological deficits and neuroinflammation in mice with traumatic brain injury by suppressing STAT3/NF-κB and inflammasome activation. Int Immunopharmacol 108:108913. https://doi.org/10.1016/j.intimp.2022.108913

Article  CAS  PubMed  Google Scholar 

Dixon KJ (2017) Pathophysiology of traumatic brain injury. Phy Med and Rehab Clinics 28(2):215–225. https://doi.org/10.1016/j.pmr.2016.12.001

Article  Google Scholar 

Ellman GL (1959) Tissue sulfhydryl groups. Arch Biochem Biophys 82(1):70–77. https://doi.org/10.1016/0003-9861(59)90090-6.h

Article  CAS  PubMed  Google Scholar 

Ellman GL, Courtney KD, Andres V Jr, Feather-Stone RM (1961) A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem Pharmacol 7:88–95

Article  CAS  PubMed  Google Scholar 

Gu W, Wu M, Zhang R et al (2025) Sufentanil enhances the cortical neurogenesis of rats with traumatic brain injury via PI3K/AKT signal pathway. Sci Rep 15(1):3986. https://doi.org/10.1038/s41598-025-88344-2

Article  CAS  PubMed  PubMed Central  Google Scholar 

Güzelad Ö, Özkan A, Parlak H et al (2021) Protective mechanism of Syringic acid in an experimental model of Parkinson’s disease. Metab Brain Dis 36(5):1003–1014. https://doi.org/10.1007/s11011-021-00704-9

Article  CAS  PubMed  Google Scholar 

Halstrom A, MacDonald E, Neil C (2017) Elevation of oxidative stress indicators in a pilot study of plasma following traumatic brain injury. J Clin Neurosci 35:104–108. https://doi.org/10.1016/j.jocn.2016.09.006

Article  CAS  PubMed  Google Scholar 

Hui Y, Zhao H, Shi L et al (2023) Traumatic brain injury-mediated neuroinflammation and neurological deficits are improved by 8-methoxypsoralen through modulating PPARγ/NF-κB pathway. Neurochem Res 48(2):625–640. https://doi.org/10.1007/s11064-022-03788-6

Article  CAS  PubMed  Google Scholar 

Kalra S, Sachdeva H, Pant AB et al (2025) Neuroprotection in traumatic brain injury: effects of alpha-asarone and Acorus calamus extract in mice using weight drop model. Naunyn-Schmiedeb Arch Pharmacol. https://doi.org/10.1007/s00210-025-03977-4

Article  Google Scholar 

King TE, Howard RL (1967) Preparations and properties of soluble NADH dehydrogenases from cardiac muscle. In: Pullman R (ed) Estabrook. Academic Press, New York

Google Scholar 

Kochanek PM, Clark RS et al (2007) TBI: pathobiology. In: Douglas IK, Ross DZ, Nathan DZ (eds) Brain injury medicine: Principles and practice. Demos Medical Publishing

Google Scholar 

Kono Y (1978) Generation of superoxide radical during autoxidation of hydroxylamine and an assay for superoxide dismutase. Arch Biochem Biophys 186(1):189–195

Article  CAS  PubMed  Google Scholar 

Koulaeinejad N, Haddadi K, Salehifar E (2019) Effects of minocycline on neurological outcomes in patients with acute traumatic brain injury: a pilot study. Iran J Pharm Res 18(2):1086. https://doi.org/10.22037/ijpr.2019.1100677

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kumar A, Rinwa P, Dhar H (2014) Microglial inhibitory effect of ginseng ameliorates cognitive deficits and neuroinflammation following traumatic head injury in rats. Inflammopharmacol 22(3):155–167. https://doi.org/10.1007/s10787-013-0187-3

Article  Google Scholar 

Liu Y, Peterson DA, Kimura H et al (1997) Mechanism of cellular 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction. J Neurochem 69(2):581–593

Article  CAS  PubMed  Google Scholar 

Lowry OH, Rosebrough NJ, Farr AL et al (1951) Protein measurement with the Folin phenol reagent. J Biol Chem 193(1):265–275

Article  CAS  PubMed  Google Scholar 

Luck H (1965) Catalase. In: Bergmeyer HU (ed) Method of enzymatic analysis. Academic Press, New York, pp 885–894

Chapter  Google Scholar 

Marmarou A, Foda MAAE, Van Den Brink W et al (1994) A new model of diffuse brain injury in rats: Part I: pathophysiology and biomechanics. J Neurosurg 80(2):291–300. https://doi.org/10.3171/jns.1994.80.2.0291

Article  CAS  PubMed  Google Scholar 

Maurice N, Liberge M, Jaouen F (2015) Striatal cholinergic interneurons control motor behavior and basal ganglia function in experimental parkinsonism. Cell Rep 13(4):657–666. https://doi.org/10.1016/j.celrep.2015.09.034

Article  CAS  PubMed