Ahmadi S, Knerr JM, Argemi L et al (2020) Scorpion venom: detriments and benefits. Biomedicines 8:118. https://doi.org/10.3390/biomedicines8050118

Article  CAS  PubMed  PubMed Central  Google Scholar 

Akef HM (2019) Anticancer and antimicrobial activities of scorpion venoms and their peptides. Toxin Rev 38:41–53. https://doi.org/10.1080/15569543.2017.1414847

Article  CAS  Google Scholar 

Al-Asmari AK, Ullah Z, Al Balowi A, Islam M (2017) In vitro determination of the efficacy of scorpion venoms as anti-cancer agents against colorectal cancer cells: a nano-liposomal delivery approach. Int J Nanomed. https://doi.org/10.2147/IJN.S123514

Article  Google Scholar 

Al-Rabia MW, Alhakamy NA, Rizg WY et al (2022) Boosting curcumin activity against human prostatic cancer PC3 cells by utilizing scorpion venom conjugated phytosomes as promising functionalized nanovesicles. Drug Deliv 29:807–820. https://doi.org/10.1080/10717544.2022.2048133

Article  CAS  PubMed  PubMed Central  Google Scholar 

Alves ÁEF, Barros ABC, Silva LCF et al (2025) Emerging trends in snake venom-loaded nanobiosystems for advanced medical applications: a comprehensive overview. Pharmaceutics 17:204. https://doi.org/10.3390/pharmaceutics17020204

Article  CAS  PubMed  PubMed Central  Google Scholar 

Attarde SS, Pandit Sv (2016) Scorpion venom as therapeutic agent-current perspective. Int J Curr Pharm Res 7:59–72. https://doi.org/10.5281/zenodo.12681160

Article  Google Scholar 

Bergeron ZL, Bingham J-P (2012) Scorpion toxins specific for potassium (K+) channels: a historical overview of peptide bioengineering. Toxins 4:1082–1119. https://doi.org/10.3390/toxins4111082

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bordon KdeCF, Cologna CT, Fornari-Baldo EC et al (2020) From animal poisons and venoms to medicines: achievements, challenges and perspectives in drug discovery. Front Pharmacol 11:1132. https://doi.org/10.3389/fphar.2020.01132

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bordon KCF, Wiezel GA, Amorim FG, Arantes EC (2015) Arthropod venom hyaluronidases: biochemical properties and potential applications in medicine and biotechnology. J Venom Anim Toxins Incl Trop Dis 21:4. https://doi.org/10.1186/s40409-015-0042-7

Article  CAS  Google Scholar 

Branco F, Cunha J, Mendes M et al (2024) Peptide-hitchhiking for the development of nanosystems in glioblastoma. ACS Nano 18:16359–16394. https://doi.org/10.1021/acsnano.4c01790

Article  CAS  PubMed  PubMed Central  Google Scholar 

Campos FV, Menezes TN, Malacarne PF et al (2016) A review on the Scorpaena plumieri fish venom and its bioactive compounds. J Venom Anim Toxins Incl Trop Dis 22:35. https://doi.org/10.1186/s40409-016-0090-7

Article  CAS  PubMed  PubMed Central  Google Scholar 

Carpena M, Nuñez-Estevez B, Soria-Lopez A, Simal-Gandara J (2020) Bee venom: an updating review of its bioactive molecules and its health applications. Nutrients 12:3360. https://doi.org/10.3390/nu12113360

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chary PS, Shaikh S, Rajana N et al (2024) Unlocking nature’s arsenal: nanotechnology for targeted delivery of venom toxins in cancer therapy. Biomater Adv 162:213903. https://doi.org/10.1016/j.bioadv.2024.213903

Article  CAS  PubMed  Google Scholar 

Choi MB, Lee Y (2024) Anticoagulant properties and therapeutic potentials of wasp venom. Entomol Res 54:e12724. https://doi.org/10.1111/1748-5967.12724

Article  CAS  Google Scholar 

Cid-Uribe JI, Veytia-Bucheli JI, Romero-Gutierrez T et al (2020) Scorpion venomics: a 2019 overview. Expert Rev Proteomics 17:67–83. https://doi.org/10.1080/14789450.2020.1705158

Article  CAS  PubMed  Google Scholar 

Cordeiro FA, Amorim FG, Anjolette FAP, Arantes EC (2015) Arachnids of medical importance in Brazil: main active compounds present in scorpion and spider venoms and tick saliva. J Venom Anim Toxins Incl Trop Dis 21:0. https://doi.org/10.1186/s40409-015-0028-5

Article  Google Scholar 

Daly NL, Seymour J, Wilson D (2014) Exploring the therapeutic potential of jellyfish venom. Future Med Chem 6:1715–1724. https://doi.org/10.4155/fmc.14.108

Article  CAS  PubMed  Google Scholar 

de Castro Mesquita P, Soares KSR, Torres-Rêgo M et al (2025) Venom-loaded cationic-functionalized poly (lactic acid) nanoparticles for serum production against Tityus serrulatus scorpion. Beilstein J Nanotechnol 16:1633–1643. https://doi.org/10.3762/bjnano.16.115

Article  CAS  Google Scholar 

de la Vega RCR, Schwartz EF, Possani LD (2010) Mining on scorpion venom biodiversity. Toxicon 56:1155–1161. https://doi.org/10.1016/j.toxicon.2009.11.010

Article  CAS  Google Scholar 

Dioguardi M, Cantore S, Sovereto D et al (2024) Therapeutic potential of Solenopsis invicta venom: a scoping review of its bioactive molecules, biological aspects, and health applications. Biomolecules 14:1499. https://doi.org/10.3390/biom14121499

Article  CAS  PubMed  PubMed Central  Google Scholar 

El-Qassas J, Abd El-Atti M, El-Badri N (2024) Harnessing the potency of scorpion venom-derived proteins: applications in cancer therapy. Bioresour Bioprocess 11:93. https://doi.org/10.1186/s40643-024-00805-0

Article  PubMed  PubMed Central  Google Scholar 

El Hidan MA, Laaradia MA, El Hiba O et al (2021) Scorpion‐derived antiviral peptides with a special focus on medically important viruses: an update. Biomed Res Int 2021:9998420. https://doi.org/10.1155/2021/9998420

Article  CAS  PubMed  PubMed Central  Google Scholar 

Elrayess RA, Mohallal ME, Mobarak YM et al (2022) Scorpion venom antimicrobial peptides induce caspase-1 dependant pyroptotic cell death. Front Pharmacol 12:788874. https://doi.org/10.3389/fphar.2021.788874

Article  CAS  PubMed  PubMed Central  Google Scholar 

Fawzy BS, Nafie MS, Ali IAI et al (2023) Scorpion venom peptide smp24 revealed apoptotic and antiangiogenic activities in solid-Ehrlich carcinoma bearing mice. Int J Pept Res Ther 29:29. https://doi.org/10.1007/s10989-023-10494-6

Article  CAS  Google Scholar 

Fernandes-Pedrosa MF, Félix-Silva J, Menezes YA (2013) Toxins from venomous animals: gene cloning, protein expression and biotechnological applications. In: An integrated view of the molecular recognition and toxinology: from analytical procedures to biomedical applications, pp 23–71. https://doi.org/10.5772/52380

Freuville L, Matthys C, Quinton L, Gillet J-P (2024) Venom-derived peptides for breaking through the glass ceiling of drug development. Front Chem 12:1465459. https://doi.org/10.3389/fchem.2024.1465459

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gláucia-Silva F, Torres JVP, Torres-Rêgo M et al (2024) Tityus stigmurus-venom-loaded cross-linked chitosan nanoparticles improve antimicrobial activity. Int J Mol Sci 25:9893. https://doi.org/10.3390/ijms25189893

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hakim MA, Yang S, Lai R (2015) Centipede venoms and their components: resources for potential therapeutic applications. Toxins 7:4832–4851. https://doi.org/10.3390/toxins7114832

Article  CAS  PubMed  PubMed Central  Google Scholar 

Joseph B, George J (2012) Scorpion toxins and its applications. Int J Toxicol Pharmacol Res 4:57–61

Google Scholar 

Kim E, Hwang DH, Mohan Prakash RL et al (2025) Animal venom in modern medicine: a review of therapeutic applications. Toxins 17:371. https://doi.org/10.3390/toxins17080371

Article  CAS