Incidence, risk factors, prognosis of periprosthetic fractures post hip fracture: unveiling protective role of anti-osteoporotic medication

Lafont C, Krams T (2022) Hip fracture and orthogeriatrics. Pathy’s Princ Prac Geriatri Med 2:992–1006

Google Scholar 

Chen J-L, Tai T-W, Chou C-Y, Ku C-K, Chien L-N, Huang T-W, Tang C-H (2022) Incidence of different types of subsequent fractures and related mortality in Taiwan. Arch Osteoporos 17:55

Article  PubMed  Google Scholar 

Schemitsch E, Adachi JD, Brown JP, Tarride J-E, Burke N, Oliveira T, Slatkovska L (2022) Hip fracture predicts subsequent hip fracture: a retrospective observational study to support a call to early hip fracture prevention efforts in post-fracture patients. Osteoporos Int 33:113–122

Article  PubMed  Google Scholar 

Reid IR, Billington EO (2022) Drug therapy for osteoporosis in older adults. Lancet 399:1080–1092

Article  PubMed  CAS  Google Scholar 

Davis S, Simpson E, Hamilton J, Martyn-St James M, Rawdin A, Wong R, Goka E, Gittoes N, Selby P (2020) Denosumab, raloxifene, romosozumab and teriparatide to prevent osteoporotic fragility fractures: a systematic review and economic evaluation. Health Technology assessment (Winchester, England) 24:1

Article  PubMed  Google Scholar 

Patsiogiannis N, Kanakaris NK, Giannoudis PV (2021) Periprosthetic hip fractures: an update into their management and clinical outcomes. EFORT Open Reviews 6:75–92

Article  PubMed  PubMed Central  Google Scholar 

Jennison T, Yarlagadda R (2018) Mortality in patients sustaining a periprosthetic fracture following a hemiarthroplasty. J Orthop 15:798–801. https://doi.org/10.1016/j.jor.2018.05.031

Article  PubMed  PubMed Central  Google Scholar 

McGraw IW, Spence SC, Baird EJ, Eckhardt SM, Ayana GE (2013) Incidence of periprosthetic fractures after hip hemiarthroplasty: are uncemented prostheses unsafe? Injury 44:1945–1948. https://doi.org/10.1016/j.injury.2013.07.023

Article  PubMed  Google Scholar 

Griffiths EJ, Cash DJ, Kalra S, Hopgood PJ (2013) Time to surgery and 30-day morbidity and mortality of periprosthetic hip fractures. Injury 44:1949–1952. https://doi.org/10.1016/j.injury.2013.03.008

Article  PubMed  CAS  Google Scholar 

Wang C-Y, Fu S-H, Yang R-S, Chen L-K, Shen L-J, Hsiao F-Y (2020) Timing of anti-osteoporosis medications initiation after a hip fracture affects the risk of subsequent fracture: a nationwide cohort study. Bone 138:115452

Article  PubMed  Google Scholar 

Hsieh CY, Su CC, Shao SC, Sung SF, Lin SJ, Kao Yang YH, Lai EC (2019) Taiwan’s National Health Insurance Research Database: past and future. Clin Epidemiol 11:349–358. https://doi.org/10.2147/clep.S196293

Article  PubMed  PubMed Central  Google Scholar 

Desai RJ, Mahesri M, Abdia Y, Barberio J, Tong A, Zhang D, Mavros P, Kim SC, Franklin JM (2018) Association of osteoporosis medication use after hip fracture with prevention of subsequent nonvertebral fractures: an instrumental variable analysis - PubMed. JAMA Netw Open 1.https://doi.org/10.1001/jamanetworkopen.2018.0826

Fu SH, Wang CY, Hung CC, Lee CC, Yang RS, Huang CC, Farn CJ, Lin WH, Chen HM, Hsiao FY, Lin JW, Li CY (2021) Increased fracture risk after discontinuation of anti-osteoporosis medications among hip fracture patients: a population-based cohort study. J Intern Med 290:1194–1205. https://doi.org/10.1111/joim.13354

Article  PubMed  CAS  Google Scholar 

Lee MT, Fu SH, Hsu CC, Chen HM, Lin JW, Tsai KS, Hwang JS, Lin SC, Wu CH, Wang CY (2023) Epidemiology and clinical impact of osteoporosis in Taiwan: a 12-year trend of a nationwide population-based study. J Formos Med Assoc 122(Suppl 1):S21-s35. https://doi.org/10.1016/j.jfma.2023.05.001

Article  PubMed  Google Scholar 

Ratnasamy PP, Rudisill KE, Oghenesume OP, Riedel MD, Grauer JN (2023) Risk of contralateral hip fracture following initial hip fracture among geriatric fragility fracture patients. JAAOS Global Research & Reviews 7:e23

Article  Google Scholar 

Fu S-H, Yu P-Y, Li C-Y, Hung C-C, Lee C-C, Chen H-Y, Tai T-W, Hwang J-S, Yang R-S, Chiang H, Lin S-Y, Wu C-H, Liao L-C, Chuang C-J, Wu C-Y, Chang C-Y, Lee M-T, Chen C-H, Wang C-Y (2023) Diagnostic accuracy of algorithms to define incident and second hip fractures: a Taiwan validation study. J Formos Med Assoc 122:S82–S91. https://doi.org/10.1016/j.jfma.2023.05.037

Article  PubMed  Google Scholar 

Mazzucchelli R, Pérez-Fernández E, Crespí N, García-Vadillo A, Rodriguez Caravaca G, Gil de Miguel A, Carmona L (2018) Second hip fracture: incidence, trends, and predictors. Calcified Tissue International. 102:619–626. https://doi.org/10.1007/s00223-017-0364-2

Article  PubMed  CAS  Google Scholar 

Yu S-F, Cheng J-S, Chen Y-C, Chen J-F, Hsu C-Y, Lai H-M, Ko C-H, Chiu W-C, Su Y-J, Cheng T-T (2019) Adherence to anti-osteoporosis medication associated with lower mortality following hip fracture in older adults: a nationwide propensity score-matched cohort study. BMC Geriatr 19:290. https://doi.org/10.1186/s12877-019-1278-9

Article  PubMed  PubMed Central  Google Scholar 

Baggott PJ, Farook MZ, Pritchard M, Singh H, Bista A, Sobti A, Unnithan A, Baggott J (2022) Periprosthetic femoral fractures and their surgical outcomes between 2011 and 2021: a single-centre observational study. Cureus 14(8). https://doi.org/10.7759/cureus.28341

Fenelon C, Murphy EP, Kearns SR, Curtin W, Murphy CG (2020) A growing challenge: the rise of femoral periprosthetic fractures - an 11-year observational study. Surgeon 18:19–23. https://doi.org/10.1016/j.surge.2019.05.001

Article  PubMed  CAS  Google Scholar 

Günther K-P, Deckert S, Lützner C, Lange T, Schmitt J, Postler A (2021) Total hip replacement for osteoarthritis—evidence-based and patient-oriented indications. Dtsch Arztebl Int 118:730

PubMed  PubMed Central  Google Scholar 

Söreskog E, Ström O, Spångéus A, Åkesson KE, Borgström F, Banefelt J, Toth E, Libanati C, Charokopou M (2020) Risk of major osteoporotic fracture after first, second and third fracture in Swedish women aged 50 years and older. Bone 134:115286

Article  PubMed  Google Scholar 

Tai TW, Huang CF, Huang HK, Yang RS, Chen JF, Cheng TT, Chen FP, Chen CH, Chang YF, Hung WC, Han DS, Chan DC, Tsai CC, Chen IW, Chan WP, Chang HJ, Hwang JS, Wu CH (2023) Clinical practice guidelines for the prevention and treatment of osteoporosis in Taiwan: 2022 update. J Formos Med Assoc 122(Suppl 1):S4–S13. https://doi.org/10.1016/j.jfma.2023.01.007

Article  PubMed  Google Scholar 

Miettinen S, Sund R, Törmä S, Kröger H (2023) How often do complications and mortality occur after operatively treated periprosthetic proximal and distal femoral fractures? A register-based study - PubMed. Clin Orthop Relat Res 481. https://doi.org/10.1097/CORR.0000000000002638.

GJ DR (2013) Periprosthetic fractures about the knee - an overview. J Knee Surg 26. https://doi.org/10.1055/s-0033-1333900

Epidemiology and characteristics of femoral periprosthetic fractures : data from the characteristics, outcomes and management of periprosthetic fracture service evaluation (COMPOSE) cohort study - PubMed. The bone and joint journal. 2022 Aug; 104-B. https://doi.org/10.1302/0301-620X.104B8.BJJ-2021-1681.R1

Gj DR, Ks L, Hc P (2011) Periprosthetic fractures: epidemiology and future projections - PubMed. J Orthop Trauma 25(Suppl):2. https://doi.org/10.1097/BOT.0b013e31821b8c28

Article  Google Scholar 

Carballido-Gamio J, Marques EA, Sigurdsson S, Siggeirsdottir K, Jensen A, Sigurdsson G, Aspelund T, Gudnason V, Lang TF, Harris TB (2024) Male-female spatio-temporal differences of age-related bone changes show faster bone deterioration in older women at femoral regions associated with incident hip fracture . J Bone Miner Res: Off J Am Soc Bone Miner Res 39. https://doi.org/10.1093/jbmr/zjae132

Helynen N, Rantanen L, Lehenkari P, Valkealahti M (2023) Predisposing factors for a second fragile hip fracture in a population of 1130 patients with hip fractures, treated at Oulu University Hospital in 2013–2016: a retrospective study. Arch Orthop Trauma Surg 143:2261-2271. https://doi.org/10.1007/s00402-022-04406-4

Tm M, Dt M, Jh D, Sw G, Ct T (2020) Anatomic and patient risk factors for postoperative periprosthetic hip fractures: a case-control study - PubMed. The Journal of arthroplasty. https://doi.org/10.1016/j.arth.2020.02.007

Article  Google Scholar 

Orwig DL, Abraham DS, Hochberg MC, Gruber-Baldini A, Guralnik JM, Cappola AR, Golden J, Hicks GE, Miller RR, Resnick B, Shardell M, Sterling RS, Bajracharya R, Magaziner J (2022) Sex differences in recovery across multiple domains among older adults with hip fracture. J Gerontol A Biol Sci Med Sci 77. https://doi.org/10.1093/gerona/glab271

Huang T-W, Wang C-J, Shih H-N, Chang Y, Huang K-C, Peng K-T, Lee MS (2017) Bone turnover and periprosthetic bone loss after cementless total hip arthroplasty can be restored by zoledronic acid: a prospective, randomized, open-label, controlled trial. BMC Musculoskelet Disord 18:1–10

Article  CAS  Google Scholar 

Papaioannou A, Kennedy CC, Dolovich L, Lau E, Adachi JD (2007) Patient adherence to osteoporosis medications: problems, consequences and management strategies. Drugs Aging 24:37–55

Article  PubMed  CAS  Google Scholar 

Cohen J (2013) Statistical power analysis for the behavioral sciences. Routledge

Book  Google Scholar 

Ayers C, Kansagara D, Lazur B, Fu R, Kwon A, Harrod C (2023) Effectiveness and Safety of treatments to prevent fractures in people with low bone mass or primary osteoporosis: a living systematic review and network meta-analysis for the American College of Physicians. Ann Intern Med 176. https://doi.org/10.7326/M22-0684

Sh F, Hk Y, Rs Y, Cc H, Jw L, Mt L, Hm C, Ch W, Cc H, Cy L, Oq G, Cy W (2025) Long dosing intervals of parenteral antiosteoporosis medications and the decrease in societal fracture risk: an 11-year nationwide population-based cohort study - PubMed. Mayo Clinic proceedings. https://doi.org/10.1016/j.mayocp.2024.05.002

Article  Google Scholar 

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