Aminoff MJ, Simon RP, Wiedemann E (1984) The hormonal responses to generalized tonic-clonic seizures. Brain 107:569–578. https://doi.org/10.1093/brain/107.2.569
Aydogan M, Aydogan A, Kara B et al (2007) Transient peripheral leukocytosis in children with afebrile seizures. J Child Neurol 22:77–79. https://doi.org/10.1177/0883073807299961
Bian X, Yang W, Lin J et al (2024) Hypothalamic-pituitary-adrenal axis and epilepsy. J Clin Neurol 20:131–139. https://doi.org/10.3988/jcn.2023.0308
Article PubMed PubMed Central Google Scholar
Biyani G, Ray SK, Chatterjee K et al (2017) Leukocyte count and C reactive protein as diagnostic factors in febrile convulsion. Asian J Med Sci 8:56–58. https://doi.org/10.3126/ajms.v8i2.16331
Dreymueller D, Pruessmeyer J, Groth E, Ludwig A (2012) The role of ADAM-mediated shedding in vascular biology. Eur J Cell Biol 91:472–485. https://doi.org/10.1016/j.ejcb.2011.09.003
Article CAS PubMed Google Scholar
Düsterhöft S, Babendreyer A, Giese AA et al (2019) Status update on iRhom and ADAM17: It’s still complicated. Biochim Biophys Acta - Mol Cell Res 1866:1567–1583. https://doi.org/10.1016/j.bbamcr.2019.06.017
Article CAS PubMed Google Scholar
Eklund CM (2009) Chapter 5 Proinflammatory cytokines in CRP baseline regulation. Adv Clin Chem 48:111–136. https://doi.org/10.1016/S0065-2423(09)48005-3
Fabene PF, Mora GN, Martinello M et al (2008) A role for leukocyte-endothelial adhesion mechanisms in epilepsy. Nat Med 14:1377–1383. https://doi.org/10.1038/nm.1878
Article CAS PubMed PubMed Central Google Scholar
Facchinetti F, Nalin A, Petraglia F et al (1985) Reduced ACTH, while normal β-endorphin CSF levels in early epileptic encephalopathies. Peptides 6:31–33. https://doi.org/10.1016/0196-9781(85)90072-5
Article CAS PubMed Google Scholar
Farhang A, Javanmard S, Mehvari J et al (2016) Inflammation and endothelium response in epileptic patients: A case-control study. Adv Biomed Res 5:131. https://doi.org/10.4103/2277-9175.187370
Article CAS PubMed PubMed Central Google Scholar
Feder A, Coplan JD, Goetz RR et al (2004) Twenty-four-hour cortisol secretion patterns in prepubertal children with anxiety or depressive disorders. Biol Psychiatry 56:198–204. https://doi.org/10.1016/j.biopsych.2004.05.005
Article CAS PubMed Google Scholar
Galea I (2021) The blood–brain barrier in systemic infection and inflammation. Cell Mol Immunol 18:2489–2501. https://doi.org/10.1038/s41423-021-00757-x
Article CAS PubMed PubMed Central Google Scholar
Garton KJ, Gough PJ, Philalay J et al (2003) Stimulated shedding of vascular cell adhesion molecule 1 (VCAM-1) is mediated by tumor necrosis factor-α-converting enzyme (ADAM 17). J Biol Chem 278:37459–37464. https://doi.org/10.1074/jbc.M305877200
Article CAS PubMed Google Scholar
Gledhill JM, Brand EJ, Pollard JR et al (2021) Association of epileptic and nonepileptic seizures and changes in circulating plasma proteins linked to neuroinflammation. Neurology 96:E1443–E1452. https://doi.org/10.1212/WNL.0000000000011552
Article CAS PubMed PubMed Central Google Scholar
Gontko-Romanowska K, Żaba Z, Panieński P et al (2017) The assessment of laboratory parameters in children with fever and febrile seizures. Brain Behav 7:3–7. https://doi.org/10.1002/brb3.720
Güneş A, Fıdan S, Dulkadır R, Ünlü E (2021) Evaluation of risk factors associated with first episode febrile seizure. Eur Rev Med Pharmacol Sci 25:7089–7092. https://doi.org/10.26355/eurrev_202111_27261
Gutiérrez-López MD, Gilsanz A, Yàñez-Mó M et al (2011) The sheddase activity of ADAM17/TACE is regulated by the tetraspanin CD9. Cell Mol Life Sci 68:3275–3292. https://doi.org/10.1007/s00018-011-0639-0
Article CAS PubMed PubMed Central Google Scholar
Hılls AG, Forsham PH, Fınch CA (1948) Changes in circulating leukocytes induced by the administration of pituitary adrenocorticotrophic hormone in man. Blood 3:755–768. https://doi.org/10.1182/blood.v3.7.755.755
Jamali S, Salzmann A, Perroud N et al (2010) Functional variant in complement C3 gene promoter and genetic susceptibility to temporal lobe epilepsy and febrile seizures. PLoS ONE 5:1–8. https://doi.org/10.1371/journal.pone.0012740
Kahveci-Türköz S, Bläsius K, Wozniak J, et al (2023) A structural model of the iRhom–ADAM17 sheddase complex reveals functional insights into its trafficking and activity. Cell Mol Life Sci 80:. https://doi.org/10.1007/s00018-023-04783-y
Kwon A, Kwak BO, Kim K et al (2018) Cytokine levels in febrile seizure patients: A systematic review and meta-analysis. Seizure 59:5–10. https://doi.org/10.1016/j.seizure.2018.04.023
Libbey JE, Kirkman NJ, Wilcox KS et al (2010) Role for complement in the development of seizures following acute viral infection. J Virol 84:6452–6460. https://doi.org/10.1128/jvi.00422-10
Article CAS PubMed PubMed Central Google Scholar
Li C, Ma W, Li S et al (2020a) The FDP/FIB ratio and blood FDP level may be related to seizures after fever in young children. Front Pediatr 8:1–10. https://doi.org/10.3389/fped.2020.00439
Li C, Zhao X, Zhao Y et al (2020b) Quantitative serum proteomic study reveals that fibrinogen-related proteins may participate in the pathophysiological process of simple febrile convulsion. J Am Soc Mass Spectrom 31:666–674. https://doi.org/10.1021/jasms.9b00100
Article CAS PubMed Google Scholar
Lin YM, Hsu CJ, Liao YY et al (2012) The CCL2/CCR2 axis enhances vascular cell adhesion molecule-1 expression in human synovial fibroblasts. PLoS ONE 7:1–10. https://doi.org/10.1371/journal.pone.0049999
Maniu I, Costea R, Maniu G, Neamtu BM (2021) Inflammatory biomarkers in febrile seizure: A comprehensive bibliometric, review and visualization analysis. Brain Sci 11:. https://doi.org/10.3390/brainsci11081077
Masri-Iraqi H, Robenshtok E, Tzvetov G et al (2014) Elevated white blood cell counts in Cushing’s disease: association with hypercortisolism. Pituitary 17:436–440. https://doi.org/10.1007/s11102-013-0522-0
Mi YM, Qi Q, Zhang L et al (2020) Assessment of serum sialic acid correlated with C3 in children with Mycoplasma pneumoniae pneumonia. J Clin Lab Anal 34:1–6. https://doi.org/10.1002/jcla.23078
Mohebbi MR, Holden KR, Mohammadi M (2004) Peripheral leukocytosis in children with febrile seizures. J Child Neurol 19:47–50. https://doi.org/10.1177/08830738040190010704
Nass RD, Wagner M, Surges R, Holdenrieder S (2020) Time courses of HMGB1 and other inflammatory markers after generalized convulsive seizures. Epilepsy Res 162:106301. https://doi.org/10.1016/j.eplepsyres.2020.106301
Article CAS PubMed Google Scholar
Park KIL, Hwang S, Son H et al (2024) Prognostication in epilepsy with integrated analysis of blood parameters and clinical data. J Clin Med 13:5517. https://doi.org/10.3390/jcm13185517
Article CAS PubMed PubMed Central Google Scholar
Pasceri V, Willerson JT, Yeh ETH (2000) Direct proinflammatory effect of C-reactive protein on human endothelial cells. Circulation 102:2165–2168. https://doi.org/10.1161/01.CIR.102.18.2165
Article CAS PubMed Google Scholar
Pickett JR, Wu Y, Zacchi LF, Ta HT (2023) Targeting endothelial vascular cell adhesion molecule-1 in atherosclerosis: drug discovery and development of vascular cell adhesion molecule-1-directed novel therapeutics. Cardiovasc Res 119:2278–2293. https://doi.org/10.1093/cvr/cvad130
Article CAS PubMed PubMed Central Google Scholar
Pinzon-Hoyos N, Li Y, McGee M et al (2025) Drug-resistant epilepsy associated with peripheral complement decreases and sex-specific cytokine imbalances: a pilot study. Sci Rep 15:5
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