Aletaha D, Neogi T, Silman AJ, Funovits J, Felson DT, Bingham CO 3rd, Birnbaum NS, Burmester GR, Bykerk VP, Cohen MD, Combe B, Costenbader KH, Dougados M, Emery P, Ferraccioli G, Hazes JM, Hobbs K, Huizinga TW, Kavanaugh A, Kay J, Kvien TK, Laing T, Mease P, Ménard HA, Moreland LW, Naden RL, Pincus T, Smolen JS, Stanislawska-Biernat E, Symmons D, Tak PP, Upchurch KS, Vencovsky J, Wolfe F, Hawker G (2010) 2010 rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative. Ann Rheum Dis 69(9):1580–1588. https://doi.org/10.1136/ard.2010.138461

Article  PubMed  Google Scholar 

Bays HE, Kirkpatrick CF, Maki KC, Toth PP, Morgan RT, Tondt J, Christensen SM, Dixon DL, Jacobson TA (2024) Obesity, dyslipidemia, and cardiovascular disease: a joint expert review from the Obesity Medicine Association and the National Lipid Association 2024. J Clin Lipidol 18(3):e320–e350. https://doi.org/10.1016/j.jacl.2024.04.001

Article  PubMed  Google Scholar 

Ben-Zvi I, Kivity S, Langevitz P, Shoenfeld Y (2012) Hydroxychloroquine: from malaria to autoimmunity. Clin Rev Allergy Immunol 42(2):145–153. https://doi.org/10.1007/s12016-010-8243-x

Article  CAS  PubMed  Google Scholar 

Cansu DU, Korkmaz C (2008) Hypoglycaemia induced by hydroxychloroquine in a non-diabetic patient treated for RA. Rheumatology (Oxford) 47(3):378–379. https://doi.org/10.1093/rheumatology/kem378

Article  CAS  PubMed  Google Scholar 

Caraba A, Stancu O, Crișan V, Georgescu D (2024) Anti TNF-alpha treatment improves microvascular endothelial dysfunction in rheumatoid arthritis patients. Int J Mol Sci 25(18):9925. https://doi.org/10.3390/ijms25189925

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen B, Chen Y, Wang Y, Xin Q, Ma D (2024) The association between rapid growth and lipid profile: a systematic review and meta-analysis. Front Endocrinol (Lausanne) 15:1353334. https://doi.org/10.3389/fendo.2024.1353334

Article  PubMed  Google Scholar 

Cho JH, Suh S (2024) Glucocorticoid-induced hyperglycemia: a neglected problem. Endocrinol Metab (Seoul) 39(2):222–238. https://doi.org/10.3803/EnM.2024.1951

Article  CAS  PubMed  Google Scholar 

del Rincón ID, Williams K, Stern MP, Freeman GL, Escalante A (2001) High incidence of cardiovascular events in a rheumatoid arthritis cohort not explained by traditional cardiac risk factors. Arthritis Rheum 44(12):2737–2745 (10.1002/1529-0131(200112)44:12<2737::AID-ART460>3.0.CO;2-%23)

Article  PubMed  Google Scholar 

Dessie G, Tadesse Y, Demelash B, Genet S (2020) Assessment of serum lipid profiles and high-sensitivity C-reactive protein among patients suffering from rheumatoid arthritis at Tikur Anbessa specialized hospital, Addis Ababa, Ethiopia: a cross-sectional study. Open Access Rheumatol 12:223–232. https://doi.org/10.2147/OARRR.S264466

Article  CAS  PubMed  PubMed Central  Google Scholar 

Fairley JL, Nikpour M, Mack HG, Brosnan M, Saracino AM, Pellegrini M, Wicks IP (2023) How toxic is an old friend? A review of the safety of hydroxychloroquine in clinical practice. Intern Med J 53(3):311–317. https://doi.org/10.1111/imj.15908

Article  PubMed  Google Scholar 

Fiehn C (2021) Glucocorticoid-free and low-dose glucocorticoid treatment of rheumatoid arthritis. Z Rheumatol 80(4):305–313. https://doi.org/10.1007/s00393-021-00973-w

Article  CAS  PubMed  Google Scholar 

Figus FA, Piga M, Azzolin I, McConnell R, Iagnocco A (2021) Rheumatoid arthritis: Extra-articular manifestations and comorbidities. Autoimmun Rev 20(4):102776. https://doi.org/10.1016/j.autrev.2021.102776

Article  CAS  PubMed  Google Scholar 

Fraenkel L, Bathon JM, England BR, St Clair EW, Arayssi T, Carandang K, Deane KD, Genovese M, Huston KK, Kerr G, Kremer J, Nakamura MC, Russell LA, Singh JA, Smith BJ, Sparks JA, Venkatachalam S, Weinblatt ME, Al-Gibbawi M, Baker JF, Barbour KE, Barton JL, Cappelli L, Chamseddine F, George M, Johnson SR, Kahale L, Karam BS, Khamis AM, Navarro-Millán I, Mirza R, Schwab P, Singh N, Turgunbaev M, Turner AS, Yaacoub S, Akl EA (2021) 2021 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis. Arthritis Care Res (Hoboken) 73(7):924–939. https://doi.org/10.1002/acr.24596

Article  PubMed  Google Scholar 

Fragoulis GE, Panayotidis I, Nikiphorou E (2020) Cardiovascular risk in rheumatoid arthritis and mechanistic links: from pathophysiology to treatment. Curr Vasc Pharmacol 18(5):431–446. https://doi.org/10.2174/1570161117666190619143842

Article  CAS  PubMed  Google Scholar 

Groenen AG, Halmos B, Tall AR, Westerterp M (2021) Cholesterol efflux pathways, inflammation, and atherosclerosis. Crit Rev Biochem Mol Biol 56(4):426–439. https://doi.org/10.1080/10409238.2021.1925217

Article  CAS  PubMed  PubMed Central  Google Scholar 

Guevara M, Ng B (2021) Positive effect of hydroxychloroquine on lipid profiles of patients with rheumatoid arthritis: a veterans affair cohort. Eur J Rheumatol 8(2):62–66. https://doi.org/10.5152/eurjrheum.2020.20193

Article  PubMed  Google Scholar 

Hajiesmaeili Y, Tamhankar P, Stranges S, Barra L (2024) Factors associated with incident cardiovascular disease in patients with rheumatoid arthritis: a scoping review. Autoimmun Rev 23(5):103539. https://doi.org/10.1016/j.autrev.2024.103539

Article  CAS  PubMed  Google Scholar 

Hodis HN, Quismorio FP Jr, Wickham E, Blankenhorn DH (1993) The lipid, lipoprotein, and apolipoprotein effects of hydroxychloroquine in patients with systemic lupus erythematosus. J Rheumatol 20(4):661–665

CAS  PubMed  Google Scholar 

Hoes JN, van der Goes MC, van Raalte DH, van der Zijl NJ, den Uyl D, Lems WF, Lafeber FP, Jacobs JW, Welsing PM, Diamant M, Bijlsma JW (2011) Glucose tolerance, insulin sensitivity and beta-cell function in patients with rheumatoid arthritis treated with or without low-to-medium dose glucocorticoids. Ann Rheum Dis 70(11):1887–1894. https://doi.org/10.1136/ard.2011.151464

Article  CAS  PubMed  Google Scholar 

Jin J (2018) Risk assessment for cardiovascular disease with nontraditional risk factors. JAMA 320(3):316. https://doi.org/10.1001/jama.2018.9122

Article  PubMed  Google Scholar 

Jorge A, Lu N, Choi H, Esdaile JM, Lacaille D, Avina-Zubieta JA (2023) Hydroxychloroquine use and cardiovascular events among patients with systemic lupus erythematosus and rheumatoid arthritis. Arthritis Care Res (Hoboken) 75(4):743–748. https://doi.org/10.1002/acr.24850

Article  CAS  PubMed  Google Scholar 

Kim JY, Lee EY, Park JK, Song YW, Kim JR, Cho KH (2016) Patients with rheumatoid arthritis show altered lipoprotein profiles with dysfunctional high-density lipoproteins that can exacerbate inflammatory and atherogenic process. PLoS ONE 11(10):e0164564. https://doi.org/10.1371/journal.pone.0164564

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lei Q, Yang J, Li L, Zhao N, Lu C, Lu A, He X (2023) Lipid metabolism and rheumatoid arthritis. Front Immunol 14:1190607. https://doi.org/10.3389/fimmu.2023.1190607

Article  CAS  PubMed  PubMed Central  Google Scholar 

Maradit-Kremers H, Crowson CS, Nicola PJ, Ballman KV, Roger VL, Jacobsen SJ, Gabriel SE (2005) Increased unrecognized coronary heart disease and sudden deaths in rheumatoid arthritis: a population-based cohort study. Arthritis Rheum 52(2):402–411. https://doi.org/10.1002/art.20853

Article  PubMed  Google Scholar 

Martín-González C, Martín-Folgueras T, Quevedo-Abeledo JC, de Vera-González A, González-Delgado A, de Armas-Rillo L, González-Gay MÁ, Ferraz-Amaro I (2022) Apolipoprotein C-III is linked to the insulin resistance and beta-cell dysfunction that are present in rheumatoid arthritis. Arthritis Res Ther 24(1):126. https://doi.org/10.1186/s13075-022-02822-w

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mir N, Chin SA, Riddell MC, Beaudry JL (2021) Genomic and non-genomic actions of glucocorticoids on adipose tissue lipid metabolism. Int J Mol Sci 22(16):8503. https://doi.org/10.3390/ijms22168503

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nicolau J, Lequerré T, Bacquet H, Vittecoq O (2017) Rheumatoid arthritis, insulin resistance, and diabetes. Jt Bone Spine 84(4):411–416. https://doi.org/10.1016/j.jbspin.2016.09.001

Article  CAS