Ahmad I, Fakhri S, Khan H, Jeandet P, Aschner M, Yu Z-L (2020) Targeting cell cycle by β-carboline alkaloids in vitro: novel therapeutic prospects for the treatment of cancer. Chem Biol Interact 330:109229. https://doi.org/10.1016/j.cbi.2020.109229
Article CAS PubMed Google Scholar
Alikiaii B, Bagherniya M, Askari G, Johnston TP, Sahebkar A (2021) The role of phytochemicals in sepsis: a mechanistic and therapeutic perspective. BioFactors 47:19–40. https://doi.org/10.1002/biof.1694
Article CAS PubMed Google Scholar
Antonia RJ, Hagan RS, Baldwin AS (2021) Expanding the view of IKK: new substrates and new biology. Trends Cell Biol 31:166–178. https://doi.org/10.1016/j.tcb.2020.12.003
Article CAS PubMed Google Scholar
Bellani G, Laffey JG, Pham T, Fan E (2016) The LUNG SAFE study: a presentation of the prevalence of ARDS according to the Berlin definition! Crit Care 20:268. https://doi.org/10.1186/s13054-016-1443-x
Article PubMed PubMed Central Google Scholar
Beutler B (2000) Tlr4: central component of the sole mammalian LPS sensor. Curr Opin Immunol 12:20–26. https://doi.org/10.1016/s0952-7915(99)00046-1
Article CAS PubMed Google Scholar
Chen ZJ (2012) Ubiquitination in signaling to and activation of IKK. Immunol Rev 246:95–106. https://doi.org/10.1111/j.1600-065X.2012.01108.x
Article CAS PubMed PubMed Central Google Scholar
Chen C, Li L, Liu X, Zhang D, Liu Y, Li Y (2023) 23-O-acetylshengmanol-3-O-α-L-arabinoside alleviates lipopolysaccharide-induced acute lung injury through inhibiting IκB/NF-κB and MAPK/AP-1 signaling pathways. J Ethnopharmacol 300:115725. https://doi.org/10.1016/j.jep.2022.115725
Article CAS PubMed Google Scholar
Cho RL, Yang CC, Lee IT, Lin CC, Chi PL, Hsiao LD, Yang CM (2016) Lipopolysaccharide induces ICAM-1 expression via a c-Src/NADPH oxidase/ROS-dependent NF-κB pathway in human pulmonary alveolar epithelial cells. American journal of physiology. Lung Cell Mol Physiol 310:L639-657. https://doi.org/10.1152/ajplung.00109.2014
Cohen P, Strickson S (2017) The role of hybrid ubiquitin chains in the MyD88 and other innate immune signalling pathways. Cell Death Differ 24:1153–1159. https://doi.org/10.1038/cdd.2017.17
Article CAS PubMed PubMed Central Google Scholar
Ding YH, Song YD, Wu YX, He HQ, Yu TH, Hu YD, Zhang DP, Jiang HC, Yu KK, Li XZ, Sun L, Qian F (2019) Isoalantolactone suppresses LPS-induced inflammation by inhibiting TRAF6 ubiquitination and alleviates acute lung injury. Acta Pharmacol Sin 40:64–74. https://doi.org/10.1038/s41401-018-0061-3
Article CAS PubMed Google Scholar
Fan H, Cui J, Liu F, Zhang W, Yang H, He N, Dong Z, Dong J (2022) Malvidin protects against lipopolysaccharide-induced acute liver injury in mice via regulating Nrf2 and NLRP3 pathways and suppressing apoptosis and autophagy. Eur J Pharmacol 933:175252. https://doi.org/10.1016/j.ejphar.2022.175252
Article CAS PubMed Google Scholar
Ganter MT, Roux J, Miyazawa B, Howard M, Frank JA, Su G, Sheppard D, Violette SM, Weinreb PH, Horan GS, Matthay MA, Pittet JF (2008) Interleukin-1beta causes acute lung injury via alphavbeta5 and alphavbeta6 integrin-dependent mechanisms. Circ Res 102:804–812. https://doi.org/10.1161/circresaha.107.161067
Article CAS PubMed PubMed Central Google Scholar
Ghosh S, Hayden MS (2008) New regulators of NF-kappaB in inflammation. Nat Rev Immunol 8:837–848. https://doi.org/10.1038/nri2423
Article CAS PubMed Google Scholar
Han S, Yuan R, Cui Y, He J, Wang QQ, Zhuo Y, Yang S, Gao H (2022) Hederasaponin C alleviates lipopolysaccharide-induced acute lung injury in vivo and in vitro through the PIP2/NF-κB/NLRP3 signaling pathway. Front Immunol 13:846384. https://doi.org/10.3389/fimmu.2022.846384
Article CAS PubMed PubMed Central Google Scholar
Hariharan A, Hakeem AR, Radhakrishnan S, Reddy MS, Rela M (2021) The role and therapeutic potential of NF-kappa-B pathway in severe COVID-19 patients. Inflammopharmacology 29:91–100. https://doi.org/10.1007/s10787-020-00773-9
Article CAS PubMed Google Scholar
Jeong Y S (2014) The role of TRAF6 phosphorylation in Src/TRAF6-mediated IKK, JNK, Akt activation and tumorigenesis. In: Graduate School of Biomedical Sciences (The Texas Medical Center Library, The University of Texas)
Jeong D, Yi YS, Sung GH, Yang WS, Park JG, Yoon K, Yoon DH, Song C, Lee Y, Rhee MH, Kim TW, Kim JH, Cho JY (2014) Anti-inflammatory activities and mechanisms of Artemisia asiatica ethanol extract. J Ethnopharmacol 152:487–496. https://doi.org/10.1016/j.jep.2014.01.030
Article CAS PubMed Google Scholar
Ji YX, Zhang P, Zhang XJ, Zhao YC, Deng KQ, Jiang X, Wang PX, Huang Z, Li H (2016) The ubiquitin E3 ligase TRAF6 exacerbates pathological cardiac hypertrophy via TAK1-dependent signalling. Nat Commun 7:11267. https://doi.org/10.1038/ncomms11267
Article CAS PubMed PubMed Central Google Scholar
Jia F, Liu Y, Dou X, Du C, Mao T, Liu X (2022a) Liensinine inhibits osteosarcoma growth by ROS-mediated suppression of the JAK2/STAT3 signaling pathway. Oxid Med Cell Longev 2022:8245614. https://doi.org/10.1155/2022/8245614
Article CAS PubMed PubMed Central Google Scholar
Jia X, Zhang K, Feng S, Li Y, Yao D, Liu Q, Liu D, Li X, Huang J, Wang H, Wang J (2022) Total glycosides of Rhodiola rosea L. attenuate LPS-induced acute lung injury by inhibiting TLR4/NF-κB pathway. Biomed pharmacother. 158:114186. https://doi.org/10.1016/j.biopha.2022.114186
Article CAS PubMed Google Scholar
Jia X, Zhang K, Feng S, Li Y, Yao D, Liu Q, Liu D, Li X, Huang J, Wang H, Wang J (2023) Total glycosides of Rhodiola rosea L. attenuate LPS-induced acute lung injury by inhibiting TLR4/NF-κB pathway. Biomed Pharmacother 158:114186. https://doi.org/10.1016/j.biopha.2022.114186
Article CAS PubMed Google Scholar
Jose RJ, Manuel A (2020) COVID-19 cytokine storm: the interplay between inflammation and coagulation. Lancet Respir Med 8:e46–e47. https://doi.org/10.1016/s2213-2600(20)30216-2
Article CAS PubMed Google Scholar
Kojima K, Arikawa T, Saita N, Goto E, Tsumura S, Tanaka R, Masunaga A, Niki T, Oomizu S, Hirashima M, Kohrogi H (2011) Galectin-9 attenuates acute lung injury by expanding CD14- plasmacytoid dendritic cell-like macrophages. Am J Respir Crit Care Med 184:328–339. https://doi.org/10.1164/rccm.201010-1566OC
Article CAS PubMed Google Scholar
Lamothe B, Besse A, Campos AD, Webster WK, Wu H, Darnay BG (2007) Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of IκB kinase activation. J Biol Chem 282:4102–4112. https://doi.org/10.1074/jbc.M609503200
Article CAS PubMed Google Scholar
Landström M (2010) The TAK1-TRAF6 signalling pathway. Int J Biochem Cell Biol 42:585–589. https://doi.org/10.1016/j.biocel.2009.12.023
Article CAS PubMed Google Scholar
Lee D, Kim JW, Lee CY, Oh J, Hwang SH, Jo M, Kim SA, Choi W, Noh JK, Yi DK, Song M, Kim HG, Cho JY (2022) Guettarda crispiflora Vahl methanol extract ameliorates acute lung injury and gastritis by suppressing Src phosphorylation. Plants. https://doi.org/10.3390/plants11243560
Article PubMed PubMed Central Google Scholar
Li X, Stark GR (2002) NFκB-dependent signaling pathways. Exp Hematol 4:285–296. https://doi.org/10.1016/s0301-472x(02)00777-4
Li Q, Verma IM (2002) NF-kappaB regulation in the immune system. Nat Rev Immunol 2:725–734. https://doi.org/10.1038/nri910
Article CAS PubMed Google Scholar
Li W, Li D, Chen Y, Abudou H, Wang H, Cai J, Wang Y, Liu Z, Liu Y, Fan H (2022) Classic signaling pathways in alveolar injury and repair involved in sepsis-induced ALI/ARDS: new research progress and prospect. Dis Markers 2022:6362344. https://doi.org/10.1155/2022/6362344
Article CAS PubMed PubMed Central Google Scholar
Li Z, Pan H, Yang J, Chen D, Wang Y, Zhang H, Cheng Y (2023) Xuanfei Baidu formula alleviates impaired mitochondrial dynamics and activated NLRP3 inflammasome by repressing NF-κB and MAPK pathways in LPS-induced ALI and inflammation models. Phytomedicine: Int J phytother phytopharmacol 108:154545. https://doi.org/10.1016/j.phymed.2022.154545
Liang L, Ye S, Jiang R, Zhou X, Zhou J, Meng S (2022) Liensinine alleviates high fat diet (HFD)-induced non-alcoholic fatty liver disease (NAFLD) through suppressing oxidative stress and inflammation via regulating TAK1/AMPK signaling. Int Immunopharmacol 104:108306. https://doi.org/10.1016/j.intimp.2021.108306
Article CAS PubMed Google Scholar
Lima JA, Hamerski L (2019) Chapter 8—Alkaloids as potential multi-target drugs to treat alzheimer’s disease. In: Ur RA (ed) Studies in natural products chemistry. Elsevier, pp 301–334
Liu D, Huang SY, Sun JH, Zhang HC, Cai QL, Gao C, Li L, Cao J, Xu F, Zhou Y, Guan CX, Jin SW, Deng J, Fang XM, Jiang JX, Zeng L (2022) Sepsis-induced immunosuppression: mechanisms, diagnosis and current treatment options. Mil Med Res 9:56. https://doi.org/10.1186/s40779-022-00422-y
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