Ahmad Mulyadi Lai HI, Chou SJ, Chien Y, Tsai PH, Chien CS, Hsu CC, Yang YP (2021) Expression of endogenous angiotensin-converting enzyme 2 in human induced pluripotent stem cell-derived retinal organoids. Int J Mol Sci. https://doi.org/10.3390/ijms22031320

Article  PubMed  PubMed Central  Google Scholar 

Arokiarajan MS, Thirunavukkarasu R, Joseph J, Ekaterina O, Aruni W (2022) Advance research in biomedical applications on marine sulfated polysaccharide. Int J Biol Macromol 194:870–881. https://doi.org/10.1016/j.ijbiomac.2021.11.142

Article  CAS  PubMed  Google Scholar 

Azouz AA, Saleh E, Abo-Saif AA (2020) Aliskiren, tadalafil, and cinnamaldehyde alleviate joint destruction biomarkers; MMP-3 and RANKL; in complete Freund’s adjuvant arthritis model: downregulation of IL-6/JAK2/STAT3 signaling pathway. Saudi Pharm J 28(9):1101–1111. https://doi.org/10.1016/j.jsps.2020.07.011

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bian J, Li Z (2021) Angiotensin-converting enzyme 2 (ACE2): SARS-CoV-2 receptor and RAS modulator. Acta Pharm Sin B 11(1):1–12. https://doi.org/10.1016/j.apsb.2020.10.006

Article  CAS  PubMed  Google Scholar 

Chan JF, Kok KH, Zhu Z, Chu H, To KK, Yuan S, Yuen KY (2020) Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan. Emerg Microbes Infect 9(1):221–236. https://doi.org/10.1080/22221751.2020.1719902

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chung CY, Majewska NI, Wang Q, Paul JT, Betenbaugh MJ (2017) SnapShot: N-glycosylation processing pathways across kingdoms. Cell 171(1):258-258 e251. https://doi.org/10.1016/j.cell.2017.09.014

Article  CAS  PubMed  Google Scholar 

D’Onofrio N, Scisciola L, Sardu C, Trotta MC, De Feo M, Maiello C, Marfella R (2021) Glycated ACE2 receptor in diabetes: open door for SARS-COV-2 entry in cardiomyocyte. Cardiovasc Diabetol 20(1):99. https://doi.org/10.1186/s12933-021-01286-7

Article  CAS  PubMed  PubMed Central  Google Scholar 

Donoghue M, Hsieh F, Baronas E, Godbout K, Gosselin M, Stagliano N, Acton S (2000) A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1–9. Circ Res 87(5):E1-9. https://doi.org/10.1161/01.res.87.5.e1

Article  CAS  PubMed  Google Scholar 

Du YM, Zheng SL, Liu L, Voglmeir J, Yedid G (2018) Analysis of N-glycans from raphanus sativus cultivars using PNGase H. J vis Exp. https://doi.org/10.3791/57979

Article  PubMed  PubMed Central  Google Scholar 

El-Shennawy L, Hoffmann AD, Dashzeveg NK, McAndrews KM, Mehl PJ, Cornish D, Liu H (2022) Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2. Nat Commun 13(1):405. https://doi.org/10.1038/s41467-021-27893-2

Article  CAS  PubMed  PubMed Central  Google Scholar 

Fujita K, Hatano K, Hashimoto M, Tomiyama E, Miyoshi E, Nonomura N, Uemura H (2021) Fucosylation in urological cancers. Int J Mol Sci. https://doi.org/10.3390/ijms222413333

Article  PubMed  PubMed Central  Google Scholar 

Garg M, Christensen B, Lubel JS (2020a) Gastrointestinal ACE2, COVID-19 and IBD: opportunity in the face of tragedy? Gastroenterology 159(4):1623-1624 e1623. https://doi.org/10.1053/j.gastro.2020.04.051

Article  CAS  PubMed  Google Scholar 

Garg M, Royce SG, Lubel JS (2020b) Letter: intestinal inflammation, COVID-19 and gastrointestinal ACE2-exploring RAS inhibitors. Aliment Pharmacol Ther 52(3):569–570. https://doi.org/10.1111/apt.15814

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gong Y, Qin S, Dai L, Tian Z (2021) The glycosylation in SARS-CoV-2 and its receptor ACE2. Signal Transduct Target Ther 6(1):396. https://doi.org/10.1038/s41392-021-00809-8

Article  CAS  PubMed  PubMed Central  Google Scholar 

Goso Y, Sugaya T, Ishihara K, Kurihara M (2017) Comparison of methods to release mucin-type O-glycans for glycomic analysis. Anal Chem 89(17):8870–8876. https://doi.org/10.1021/acs.analchem.7b01346

Article  CAS  PubMed  Google Scholar 

Han F, Xiao Y, Lee IS (2021) Microbial conjugation studies of licochalcones and xanthohumol. Int J Mol Sci. https://doi.org/10.3390/ijms22136893

Article  PubMed  PubMed Central  Google Scholar 

He Y, Liu S, Kling DE, Leone S, Lawlor NT, Huang Y, Newburg DS (2016) The human milk oligosaccharide 2’-fucosyllactose modulates CD14 expression in human enterocytes, thereby attenuating LPS-induced inflammation. Gut 65(1):33–46. https://doi.org/10.1136/gutjnl-2014-307544

Article  CAS  PubMed  Google Scholar 

He W, Sun H, Su L, Zhou D, Zhang X, Shanggui D, Chen Y (2020) Structure and anticoagulant activity of a sulfated fucan from the sea cucumber acaudina leucoprocta. Int J Biol Macromol 164:87–94. https://doi.org/10.1016/j.ijbiomac.2020.07.080

Article  CAS  PubMed  Google Scholar 

Huang WB, Zou GJ, Tang GH, Sun XY, Ouyang JM (2021) Regulation of laminaria polysaccharides with different degrees of sulfation during the growth of calcium oxalate crystals and their protective effects on renal epithelial cells. Oxid Med Cell Longev 2021:5555796. https://doi.org/10.1155/2021/5555796

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li Y, Zhou W, Yang L, You R (2020) Physiological and pathological regulation of ACE2, the SARS-CoV-2 receptor. Pharmacol Res 157:104833. https://doi.org/10.1016/j.phrs.2020.104833

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li S, Yang R, Zhang D, Han P, Xu Z, Chen Q, Gao GF (2022a) Cross-species recognition and molecular basis of SARS-CoV-2 and SARS-CoV binding to ACE2s of marine animals. Natl Sci Rev 9(9):nwac122. https://doi.org/10.1093/nsr/nwac122

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li Z, Wang K, Ji X, Wang H, Zhang Y (2022b) ACE2 suppresses the inflammatory response in LPS-induced porcine intestinal epithelial cells via regulating the NF-kappaB and MAPK pathways. Peptides 149:170717. https://doi.org/10.1016/j.peptides.2021.170717

Article  CAS  PubMed  Google Scholar 

Lopez-Cortes R, Correa Pardo I, Muinelo-Romay L, Fernandez-Briera A, Gil-Martin E (2023) Core fucosylation mediated by the FucT-8 enzyme affects TRAIL-induced apoptosis and sensitivity to chemotherapy in human SW480 and SW620 colorectal cancer cells. Int J Mol Sci. https://doi.org/10.3390/ijms241511879

Article  PubMed  PubMed Central  Google Scholar 

Ma J, Li Q, Tan H, Jiang H, Li K, Zhang L, Yin H (2019) Unique N-glycosylation of a recombinant exo-inulinase from Kluyveromyces cicerisporus and its effect on enzymatic activity and thermostability. J Biol Eng 13:81. https://doi.org/10.1186/s13036-019-0215-y

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mehdipour AR, Hummer G (2021) Dual nature of human ACE2 glycosylation in binding to SARS-CoV-2 spike. Proc Natl Acad Sci USA. https://doi.org/10.1073/pnas.2100425118

Article  PubMed  PubMed Central  Google Scholar 

Miao S, Shu D, Zhu Y, Lu M, Zhang Q, Pei Y, Ming ZY (2019) Cancer cell-derived immunoglobulin G activates platelets by binding to platelet FcgammaRIIa. Cell Death Dis 10(2):87. https://doi.org/10.1038/s41419-019-1367-x

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mu C, Cai Z, Bian G, Du Y, Ma S, Su Y, Zhu W (2019) New insights into porcine milk N-glycome and the potential relation with offspring gut microbiome. J Proteome Res 18(3):1114–1124. https://doi.org/10.1021/acs.jproteome.8b00789

Article  CAS  PubMed  Google Scholar 

Narula S, Yusuf S, Chong M, Ramasundarahettige C, Rangarajan S, Bangdiwala SI, Pare G (2020) Plasma ACE2 and risk of death or cardiometabolic diseases: a case-cohort analysis. Lancet 396(10256):968–976. https://doi.org/10.1016/S0140-6736(20)31964-4

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nguyen K, Chakraborty S, Mansbach RA, Korber B, Gnanakaran S (2021) Exploring the role of glycans in the interaction of SARS-CoV-2 RBD and human receptor ACE2. Viruses. https://doi.org/10.3390/v13050927

Article  PubMed  PubMed Central  Google Scholar 

Oshima K, Han X, Ouyang Y, El Masri R, Yang Y, Haeger SM, Schmidt EP (2019) Loss of endothelial sulfatase-1 after experimental sepsis attenuates subsequent pulmonary inflammatory responses. Am J Physiol Lung Cell Mol Physiol 317(5):L667–L677. https://doi.org/10.1152/ajplung.00175.2019

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ponticelli C, Campise M (2022) COVID-19 vaccination in kidney transplant candidates and recipients. Vaccines (basel). https://doi.org/10.3390/vaccines10111808

Article  PubMed  Google Scholar