The Geoepidemiology of Autoimmune Hepatitis

Mieli-Vergani G, Vergani D, Czaja AJ, Manns MP, Krawitt EL, Vierling JM et al (2018) Autoimmune hepatitis. Nat Rev Dis Primers 4:18017

Article  PubMed  Google Scholar 

Floreani A, Restrepo-Jiménez P, Secchi MF, De Martin S, Leung PSC, Krawitt E et al (2018) Etiopathogenesis of autoimmune hepatitis. J Autoimmun 95:133–143

Article  CAS  PubMed  Google Scholar 

Czaja AJ (2022) Epigenetic aspects and prospects in autoimmune hepatitis. Front Immunol 13:921765

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lin R, Zhou L, Zhang J, Wang B (2015) Abnormal intestinal permeability and microbiota in patients with autoimmune hepatitis. Int J Clin Exp Pathol 8:5153–5160

PubMed  PubMed Central  Google Scholar 

Lerner A, Matthias T (2015) Changes in intestinal tight junction permeability associated with industrial food additives explain the rising incidence of autoimmune disease. Autoimmun Rev 14:479–489

Article  CAS  PubMed  Google Scholar 

Hahn JW, Yang HR, Moon JS, Chang JY, Lee K, Kim GA et al (2023) Global incidence and prevalence of autoimmune hepatitis, 1970–2022: a systematic review and meta-analysis. EClinicalMedicine 65:102280

Article  PubMed  PubMed Central  Google Scholar 

Lv T, Li M, Zeng N, Zhang J, Li S, Chen S et al (2019) Systematic review and meta-analysis on the incidence and prevalence of autoimmune hepatitis in Asian, European, and American population. J Gastroenterol Hepatol 34:1676–1684

Article  PubMed  Google Scholar 

Trivedi PJ, Hirschfield GM (2021) Recent advances in clinical practice: epidemiology of autoimmune liver diseases. Gut 70:1989–2003

Article  PubMed  Google Scholar 

Webb GJ, Ryan RP, Marshall TP, Hirschfield GM (2021) The epidemiology of UK autoimmune liver disease varies with geographic latitude. Clin Gastroenterol Hepatol 19:2587–2596

Article  PubMed  PubMed Central  Google Scholar 

Bittermann T, Lewis JD, Levy C, Goldberg DS (2023) Sociodemographic and geographic differences in the US epidemiology of autoimmune hepatitis with and without cirrhosis. Hepatology 77:367–378

Article  PubMed  Google Scholar 

Verma S, Torbenson M, Thuluvath PJ (2007) The impact of ethnicity on the natural history of autoimmune hepatitis. Hepatology 46:1828–1835

Article  PubMed  Google Scholar 

Katsumi T, Ueno Y (2022) Epidemiology and surveillance of autoimmune hepatitis in Asia. Liver Int 42:2015–2022

Article  CAS  PubMed  Google Scholar 

Costaguta A, González A, Pochettino S, Trotta L, Vicentín R, Wagener M (2018) Incidence and clinical features of autoimmune hepatitis in the province of Santa Fe (Argentina). J Pediatr Gastroenterol Nutr 67:e107–e110

Article  PubMed  Google Scholar 

Jiménez-Rivera C, Ling SC, Ahmed N, Yap J, Aglipay M, Barrowman N et al (2015) Incidence and characteristics of autoimmune hepatitis. Pediatrics 136:e1237-1248

Article  PubMed  Google Scholar 

Deneau M, Jensen MK, Holmen J, Williams MS, Book LS, Guthery SL (2013) Primary sclerosing cholangitis, autoimmune hepatitis, and overlap in Utah children: epidemiology and natural history. Hepatology 58:1392–1400

Article  PubMed  Google Scholar 

Sutton H, Tayler R, Chalmers I, Cowieson J, Fraser K, Henderson P et al (2022) The epidemiology of pediatric autoimmune hepatitis in Scotland: a national cohort study. JPGN Rep 3:e223

Article  PubMed  PubMed Central  Google Scholar 

Chung HV, Riley M, Ho JK, Leung B, Jevon GP, Arbour LT et al (2007) Retrospective review of pediatric and adult autoimmune hepatitis in two quaternary care centres in British Columbia: increased prevalence seen in British Columbia’s First Nations community. Can J Gastroenterol 21:565–568

Article  CAS  PubMed  PubMed Central  Google Scholar 

Takahashi A, Ohira H, Abe K, Zeniya M, Abe M, Arinaga-Hino T et al (2020) Increasing incidence of acute autoimmune hepatitis: a nationwide survey in Japan. Sci Rep 10:14250

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tanaka A, Mori M, Matsumoto K, Ohira H, Tazuma S, Takikawa H (2019) Increase trend in the prevalence and male-to-female ratio of primary biliary cholangitis, autoimmune hepatitis, and primary sclerosing cholangitis in Japan. Hepatol Res 49:881–889

Article  CAS  PubMed  Google Scholar 

Sharma R, Verna EC, Söderling J, Roelstraete B, Hagström H, Ludvigsson JF (2021) Increased mortality risk in autoimmune hepatitis: a nationwide population-based cohort study with histopathology. Clin Gastroenterol Hepatol 19:2636-2647.e2613

Article  PubMed  Google Scholar 

Grønbæk L, Vilstrup H, Jepsen P (2014) Autoimmune hepatitis in Denmark: incidence, prevalence, prognosis, and causes of death. A nationwide registry-based cohort study. J Hepatol 60:612–617

Article  PubMed  Google Scholar 

Grønbaek L, Otete H, Ban L, Crooks C, Card T, Jepsen P et al (2020) Incidence, prevalence and mortality of autoimmune hepatitis in England 1997–2015. a population-based cohort study. Liver Int 40:1634–1644

Article  PubMed  Google Scholar 

Danielsson Borssén Å, Marschall HU, Bergquist A, Rorsman F, Weiland O, Kechagias S et al (2017) Epidemiology and causes of death in a Swedish cohort of patients with autoimmune hepatitis. Scand J Gastroenterol 52:1022–1028

PubMed  Google Scholar 

Puustinen L, Barner-Rasmussen N, Pukkala E, Färkkilä M (2019) Incidence, prevalence, and causes of death of patients with autoimmune hepatitis: a nationwide register-based cohort study in Finland. Dig Liver Dis 51:1294–1299

Article  PubMed  Google Scholar 

Yang F, Wang Q, Bian Z, Ren LL, Jia J, Ma X (2015) Autoimmune hepatitis: east meets west. J Gastroenterol Hepatol 30:1230–1236

Article  PubMed  Google Scholar 

van Gerven NM, de Boer YS, Zwiers A, Verwer BJ, Drenth JP, van Hoek B et al (2015) HLA-DRB1*03:01 and HLA-DRB1*04:01 modify the presentation and outcome in autoimmune hepatitis type-1. Genes Immun 16:247–252

Article  PubMed  Google Scholar 

Kirstein MM, Metzler F, Geiger E, Heinrich E, Hallensleben M, Manns MP et al (2015) Prediction of short- and long-term outcome in patients with autoimmune hepatitis. Hepatology 62:1524–1535

Article  CAS  PubMed  Google Scholar 

Yao J, Jiang SF, Kapoor C, Balasubramanian S, Ramalingam ND, Saxena V et al (2025) The prevalence of autoimmune hepatitis is rising: estimates and trends from a large, multi-ethnic cohort in the United States. Hepatol Commun 9:e0824

Article  PubMed  PubMed Central  Google Scholar 

de Boer YS, Gerussi A, van den Brand FF, Wong GW, Halliday N, Liberal R et al (2019) Association between black race and presentation and liver-related outcomes of patients with autoimmune hepatitis. Clin Gastroenterol Hepatol Off Clin Pract J Am Gastroenterol Assoc 17:1616-1624.e1612

Google Scholar 

Palle SK, Naik KB (2019) Racial disparities in presentation and outcomes of paediatric autoimmune hepatitis. Liver Int 39:976–984

Article  PubMed  Google Scholar 

Lee DU, Kwon J, Koo C, Han J, Fan GH, Jung D et al (2023) Clinical implications of gender and race in patients admitted with autoimmune hepatitis: updated analysis of US hospitals. Frontline Gastroenterol 14:111–123

Article  PubMed  Google Scholar 

Wen JW, Kohn MA, Wong R, Somsouk M, Khalili M, Maher J et al (2018) Hospitalizations for autoimmune hepatitis disproportionately affect Black and Latino Americans. Am J Gastroenterol 113:243–253

Article  PubMed  PubMed Central  Google Scholar 

McCabe M, Rush N, Lammert C, Patidar KR, Nephew L, Saxena R et al (2021) Hla-dr mismatch and Black race are associated with recurrent autoimmune hepatitis after liver transplantation. Transplant Direct 7:e714

Article  PubMed  PubMed Central  Google Scholar 

Wong RJ, Gish R, Frederick T, Bzowej N, Frenette C (2012) The impact of race/ethnicity on the clinical epidemiology of autoimmune hepatitis. J Clin Gas

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