Decoding vascular calcification: mechanistic insights and translational strategies

Strauss HW et al (2019) Vascular calcification: the evolving relationship of vascular calcification to major acute coronary events. J Nucl Med 60(9):1207–1212

Article  PubMed  CAS  Google Scholar 

Kristensen AT, Jakobsen JC, Olsen NT (2022) Percutaneous coronary intervention in calcified stenoses: a protocol for a systematic review with meta-analysis, trial sequential analysis and network meta-analysis. BMJ Open 12(9):e063884

Article  Google Scholar 

London GM et al (2003) Arterial media calcification in end-stage renal disease: impact on all-cause and cardiovascular mortality. Nephrol Dialysis Transplantation 18(9):1731–1740

Article  Google Scholar 

Russo D et al (2011) Progression of coronary artery calcification and cardiac events in patients with chronic renal disease not receiving Dialysis. Kidney Int 80(1):112–118

Article  PubMed  PubMed Central  CAS  Google Scholar 

Cozzolino M et al (2018) Cardiovascular disease in Dialysis patients. Nephrol Dialysis Transplantation 33(suppl3):iii28–iii34

Article  CAS  Google Scholar 

Modi ZJ et al (2019) Risk of cardiovascular disease and mortality in young adults with end-stage renal disease: an analysis of the US renal data system. JAMA Cardiol 4(4):353–362

Article  PubMed  PubMed Central  Google Scholar 

Fuery MA et al (2018) Vascular ossification: Pathology, mechanisms, and clinical implications. Bone 109:28–34

Article  PubMed  CAS  Google Scholar 

Bertazzo S et al (2013) Nano-analytical electron microscopy reveals fundamental insights into human cardiovascular tissue calcification. Nat Mater 12(6):576

Article  PubMed  PubMed Central  CAS  Google Scholar 

Singh A, Tandon S, Tandon C (2021) An update on vascular calcification and potential therapeutics. Mol Biol Rep 48(1):887–896

Article  PubMed  CAS  Google Scholar 

Ren S-C et al (2022) Vascular calcification in chronic kidney disease: an update and perspective. Aging Disease 13(3):673

Article  PubMed  PubMed Central  Google Scholar 

Wu M, Rementer C, Giachelli CM (2013) Vascular calcification: an update on mechanisms and challenges in treatment. Calcif Tissue Int 93:365–373

Article  PubMed  PubMed Central  CAS  Google Scholar 

Montezano AC et al (2010) Vascular smooth muscle cell differentiation to an osteogenic phenotype involves TRPM7 modulation by magnesium. Hypertension 56(3):453–462

Article  PubMed  CAS  Google Scholar 

Louvet L et al (2012) Magnesium prevents phosphate-induced calcification in human aortic vascular smooth muscle cells. Nephrol Dialysis Transplantation 28(4):869–878

Article  Google Scholar 

Van den Broek F, Beynen A (1998) The influence of dietary phosphorus and magnesium concentrations on the calcium content of heart and kidneys of DBA/2 and NMRI mice. Lab Anim 32(4):483–491

Article  PubMed  Google Scholar 

Pen J et al (2012) The effect of the magnesium supplementation on vascular calcification in rats. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese. J Appl Physiol 28(1):20–23

Google Scholar 

Yao Z et al (2018) Magnesium citrate protects against vascular calcification in an Adenine-induced chronic renal failure rat model. J Cardiovasc Pharmacol 72(6):270–276

Article  PubMed  CAS  Google Scholar 

Hou M et al (2016) Curcumin attenuates osteogenic differentiation and calcification of rat vascular smooth muscle cells. Mol Cell Biochem 420(1):151–160

Article  PubMed  CAS  Google Scholar 

Chen Y et al (2019) Controlled-release Curcumin attenuates progression of tendon ectopic calcification by regulating the differentiation of tendon stem/progenitor cells. Mater Sci Engineering: C 103:109711

Article  CAS  Google Scholar 

Zhou T et al (2020) Curcumin inhibits calcification of human aortic valve interstitial cells by interfering NF-κB, AKT, and ERK pathways. Phytother Res 34(8):2074–2081

Article  PubMed  CAS  Google Scholar 

Brodeur MR et al (2014) Reduction of advanced-glycation end products levels and Inhibition of RAGE signaling decreases rat vascular calcification induced by diabetes. PLoS ONE 9(1):e85922

Article  PubMed  PubMed Central  Google Scholar 

Feng W et al (2016) Apocynin attenuates angiotensin II-induced vascular smooth muscle cells osteogenic switching via suppressing extracellular signal-regulated kinase 1/2. Oncotarget 7(50):83588

Article  PubMed  PubMed Central  Google Scholar 

Manivannan J et al (2013) Diosgenin attenuates vascular calcification in chronic renal failure rats. Mol Cell Biochem 378(1):9–18

Article  PubMed  CAS  Google Scholar 

Manivannan J et al (2014) Diosgenin interferes coronary vasoconstriction and inhibits osteochondrogenic transdifferentiation of aortic VSMC in CRF rats. Biochimie 102:183–187

Article  PubMed  CAS  Google Scholar 

Liu H et al (2019) Puerarin inhibits vascular calcification of uremic rats. Eur J Pharmacol 855:235–243

Article  PubMed  CAS  Google Scholar 

Zhang P et al (2016) Resveratrol ameliorated vascular calcification by regulating Sirt-1 and Nrf2. In: Transplantation proceedings. Elsevier

Chang X-y et al (2017) Quercetin attenuates vascular calcification through suppressed oxidative stress in adenine-induced chronic renal failure rats. BioMed Res Int 2017

Zhou P et al (2019) Ginsenoside Rb1 ameliorates CKD-associated vascular calcification by inhibiting the Wnt/β‐catenin pathway. J Cell Mol Med 23(10):7088–7098

Article  PubMed  PubMed Central  CAS  Google Scholar 

Liu X et al (2021) Spermidine inhibits vascular calcification in chronic kidney disease through modulation of SIRT1 signaling pathway. Aging Cell 20(6):e13377

Article  PubMed  PubMed Central  CAS  Google Scholar 

Jiang W, Ruan W, Wang Z (2022) Dendrobium officinale polysaccharide inhibits vascular calcification via anti-inflammatory and anti‐apoptotic effects in chronic kidney disease. FASEB J 36(9):e22504

Article  PubMed  CAS  Google Scholar 

Tani T et al (2020) Inhibition of tissue-nonspecific alkaline phosphatase protects against medial arterial calcification and improves survival probability in the CKD‐MBD mouse model. J Pathol 250(1):30–41

Article  PubMed  CAS  Google Scholar 

Perelló J et al (2020) Mechanism of action of SNF472, a novel calcification inhibitor to treat vascular calcification and calciphylaxis. Br J Pharmacol 177(19):4400–4415

Article  PubMed  PubMed Central  Google Scholar 

Helas S et al (2009) Inhibition of receptor activator of NF-κB ligand by denosumab attenuates vascular calcium deposition in mice. Am J Pathol 175(2):473–478

Article  PubMed  PubMed Central  CAS  Google Scholar 

Lei Y et al (2013) Efficacy of reversal of aortic calcification by chelating agents. Calcif Tissue Int 93:426–435

Article  PubMed  PubMed Central  CAS  Google Scholar 

Lei Y, Nosoudi N, Vyavahare N (2014) Targeted chelation therapy with EDTA-loaded albumin nanoparticles regresses arterial calcification without causing systemic side effects. J Controlled Release 196:79–86

Article  CAS  Google Scholar 

Karamched SR et al (2019) Site-specific chelation therapy with EDTA-loaded albumin nanoparticles reverses arterial calcification in a rat model of chronic kidney disease. Sci Rep 9(1):2629

Comments (0)

No login
gif