Gallic acid enhanced reproductive function by modulating oxidative stress mediators in gentamicin-treated rats

Abel M, Baker P, Charlton H, Monteiro A, Verhoeven G, De Gendt K et al (2008) Spermatogenesis and Sertoli cell activity in mice lacking Sertoli cell receptors for follicle-stimulating hormone and androgen. Endocrinology 149(7):3279–3285

CAS  PubMed  Google Scholar 

Acharya UR, Mishra M, Patro J, Panda MKJ, Panda MK (2008) Effect of vitamins C and E on spermatogenesis in mice exposed to cadmium. Reprod Toxicol 25(1):84–88

CAS  PubMed  Google Scholar 

Altındağ F, Meydan İ (2021) Evaluation of protective effects of gallic acid on cisplatin-induced testicular and epididymal damage. Andrologia 53(10):e14189

PubMed  Google Scholar 

Aly HJH (2019a) Testicular toxicity of gentamicin in adult rats: ameliorative effect of lycopene. Hum Exp Toxicol 38(11):1302–1313

CAS  PubMed  Google Scholar 

Aly H (2019b) Testicular toxicity of gentamicin in adult rats: ameliorative effect of lycopene. Hum Exp Toxicol 38(11):1302–1313

CAS  PubMed  Google Scholar 

Aly HA, Hassan MH (2018a) Potential testicular toxicity of gentamicin in adult rats. Biochem Biophys Res Commun 497(1):362–367

CAS  PubMed  Google Scholar 

Aly HA, Hassan MH (2018b) Potential testicular toxicity of gentamicin in adult rats. Biochem Biophys Res Commun 497(1):362–367

CAS  PubMed  Google Scholar 

Aly HA, Domènech Ò, Abdel-Naim ABJF, toxicology c (2009) Aroclor 1254 impairs spermatogenesis and induces oxidative stress in rat testicular mitochondria. Food Chem Toxicol 47(8):1733–1738

CAS  PubMed  Google Scholar 

Aly HA, Khafagy RMJF, Toxicology C (2014) Taurine reverses endosulfan-induced oxidative stress and apoptosis in adult rat testis. Food Chem Toxicol 64:1–9

CAS  PubMed  Google Scholar 

Badkoobeh P, Parivar K, Kalantar SM, Hosseini SD, Salabat AJ (2013) Effect of nano-zinc oxide on doxorubicin-induced oxidative stress and sperm disorders in adult male wistar rats. Iran J Reprod Med 11(5):355

CAS  PubMed  PubMed Central  Google Scholar 

Bai J, Zhang Y, Tang C, Hou Y, Ai X, Chen X et al (2021a) Gallic acid: pharmacological activities and molecular mechanisms involved in inflammation-related diseases. Biomed Pharmacother 133:110985

CAS  PubMed  Google Scholar 

Bai J, Zhang Y, Tang C, Hou Y, Ai X, Chen X et al (2021b) Gallic acid: pharmacological activities and molecular mechanisms involved in inflammation-related diseases. Biomed Pharmacother 133:110985

CAS  PubMed  Google Scholar 

Bielanski AJT (2007) Disinfection procedures for controlling microorganisms in the semen and embryos of humans and farm animals. Theriogenology 68(1):1–22

CAS  PubMed  Google Scholar 

Bischoff A, Meier C, Roth FJ (1977) Gentamicin neurotoxicity (polyneuropathy–encephalopathy). Schweizerische Medizinische Wochenschrift 107(1):3–8

Bonanno O, Romeo G, Asero P, Pezzino FM, Castiglione R, Burrello N et al (2016) Sperm of patients with severe asthenozoospermia show biochemical, molecular and genomic alterations. Reproduction 152(6):695–704

CAS  PubMed  Google Scholar 

Bukhari AS, Illahi M, Haque AU (2019) Protective effects of vitamin C and E in gentamicin induced testicular toxicity in albino mice. Int J Pathol 144–150

Chang C, Chen Y-T, Yeh S-D, Xu Q, Wang R-S, Guillou F et al (2004) Infertility with defective spermatogenesis and hypotestosteronemia in male mice lacking the androgen receptor in Sertoli cells. Proc Natl Acad Sci USA 101(18):6876–6881

CAS  PubMed  PubMed Central  Google Scholar 

Demir A, Türker P, Önol FF, Sirvanci S, Findik A, Tarcan T (2007) Effect of experimentally induced Escherichia coli epididymo-orchitis and ciprofloxacin treatment on rat spermatogenesis. Int J Urol 14(3):268–272

CAS  PubMed  Google Scholar 

Dludla PV, Nkambule BB, Jack B, Mkandla Z, Mutize T, Silvestri S et al (2018) Inflammation and oxidative stress in an obese state and the protective effects of gallic acid. Nutrients 11(1):23

PubMed  PubMed Central  Google Scholar 

Foster DNJI (2023) Male infertility. InnovAiT Educ Inspir Gen Pract 16(12):589–595

Google Scholar 

Gilbertson J (2012) Bancroft's theory and practice of histological techniques. Churchill Livingstone

Grill MF, Maganti RKJBjocp (2011) Neurotoxic effects associated with antibiotic use: management considerations. Br J Clin Pharmacol 72(3):381–393

CAS  PubMed  PubMed Central  Google Scholar 

Hamoud AE (2019) Possible role of selenium nano-particles on gentamicin-induced toxicity in rat testis: morphological and morphometric study. Egypt J Histol 42(4):861–873

Google Scholar 

Hamzeh M, Hosseinimehr SJ, Karimpour A, Mohammadi HR, Khalatbary AR, Amiri FT (2019) Cerium oxide nanoparticles protect cyclophosphamide-induced testicular toxicity in mice. Int J Prevent Med 10

Hashemitabar M, Heidari E, Orazizadeh M, Sabbagh S, Afrough M, Dastoorpoor M et al (2018) Cytochrome C oxidase 6B2 reflects the mitochondrial status through the oxidative phosphorylation. Iran Red Crescent Med J 20(12):10

Google Scholar 

Holdcraft RW, Braun RE (2004) Androgen receptor function is required in Sertoli cells for the terminal differentiation of haploid spermatids. Development. https://doi.org/10.1242/dev.00957

PubMed  Google Scholar 

Hosseinzadeh A, Mehrzadi S, Siahpoosh A, Basir Z, Bahrami N, Goudarzi M (2022) Gallic acid ameliorates di-(2-ethylhexyl) phthalate-induced testicular injury in adult mice. Hum Exp Toxicol 41:09603271221078867

CAS  Google Scholar 

Huhtaniemi IT, Yamamoto M, Ranta T, Jalkanen J, Jaffe RB (1987) Follicle-stimulating hormone receptors appear earlier in the primate fetal testis than in the ovary. J Clin Endocrinol Metab 65(6):1210–1214

CAS  PubMed  Google Scholar 

Jalili C, Korani M, Pazhouhi M, Ghanbari A, Zhaleh M, Davoudi S et al (2021) Protective effect of gallic acid on nicotine-induced testicular toxicity in mice. Res Pharm Sci 16(4):414–424

PubMed  PubMed Central  Google Scholar 

Javadneia A, Moghadam MT, Alivand A, Kheradmand A, Zargar M, Sabbagh SJN (2019) Sperm DNA damage before and after kidney transplantation 11(1)

Jungwirth A, Giwercman A, Tournaye H, Diemer T, Kopa Z, Dohle G et al (2012) European association of urology guidelines on male infertility: the 2012 update. Eur Urol 62(2):324–332

PubMed  Google Scholar 

Kao S-H, Chao H-T, Chen H-W, Hwang TI, Liao T-L, Wei Y-HJF et al (2008) Increase of oxidative stress in human sperm with lower motility. Fertil Steril 89(5):1183–1190

CAS  PubMed  Google Scholar 

Kerr JJR (1992) Spontaneous degeneration of germ cells in normal rat testis: assessment of cell types and frequency during the spermatogenic cycle. Reproduction 95(3):825–830

CAS  Google Scholar 

Khaki A (2015) Assessment on the adverse effects of aminoglycosides and flouroquinolone on sperm parameters and male reproductive tissue: a systematic review. Iran J Reprod Med 13(3):125

PubMed  PubMed Central  Google Scholar 

Khaki A, Novin MG, Khaki AA, Nouri M, Sanati E, Nikmanesh MJPjobsP (2008) Comparative study of the effects of gentamicin, neomycin, streptomycin and ofloxacin antibiotics on sperm parameters and testis apoptosis in rats. Pak J Biol Sci 11(13):1683–1689

CAS  PubMed  Google Scholar 

Khaki A, Heydari M, Ghafari NM, Khaki AA (2008) Adverse effects of ciprofloxacin on testis apoptosis and sperm parameters in rats

Khordad E, Akbaribazm M, Hosseini SM (2024) Heracleum persicum L. extract protects gentamicin-induced testicular toxicity

Kim SH, Lee IC, Baek HS, Shin IS, Moon C, Kim SH et al (2014) Melatonin prevents gentamicin-induced testicular toxicity and oxidative stress in rats. Andrologia 46(9):1032–1040

CAS  PubMed  Google Scholar 

Kuppan G, Balasubramanyam J, Monickaraj F, Srinivasan G, Mohan V, Balasubramanyam MJC (2010) Transcriptional regulation of cytokines and oxidative stress by gallic acid in human THP-1 monocytes. Cytokine 49(2):229–234

CAS  PubMed  Google Scholar 

Lanzafame FM, La Vignera S, Vicari E, Calogero AE (2009) Oxidative stress and medical antioxidant treatment in male infertility. Reprod Biomed Online 19(5):638–659

CAS  PubMed  Google Scholar 

Magli MC, Gianaroli L, Fiorentino A, Ferraretti A, Fortini D, Panzella SJHr (1996) Fertilization and early embryology: improved cleavage rate of human embryos cultured in antibiotic-free medium. Hum Reprod 11(7):1520–1524

CAS  PubMed  Google Scholar 

Mattappalil A, Mergenhagen KA (2014) Neurotoxicity with antimicrobials in the elderly: a review 36(11):1489–1511

Mehraban Z, Ghaffari Novin M, Golmohammadi MG, Sagha M, Pouriran K, Nazarian HJJocb (2019) Protective effect of gallic acid on apoptosis of sperm and in vitro fertilization in adult male mice treated with cyclophosphamide. J Cell Biochem 120(10):17250–17257

CAS  PubMed  Google Scholar 

Narayana KJTJots (2008) An aminoglycoside antibiotic gentamycin induces oxidative stress, reduces antioxidant reserve and impairs spermatogenesis in rats. J Toxicol Sci 33(1):85–96

CAS  PubMed  Google Scholar 

Nouri M, Khaki A, Fathiazar F, Rashidi MR (2009) The protective effects of carrot seed extract on spermatogenesis and cauda epididymal sperm reserves in gentamicin treated rats

Oliva A, Giami A, Multigner LJJoa (2002) Environmental agents and erectile dysfunction: a study in a consulting population. J Androl 23(4):546–550

PubMed  Google Scholar 

Oyagbemi A, Omobowale T, Saba A, Adedara I, Olowu E, Akinrinde A et al (2016) Gallic acid protects against cyclophosphamide-induced toxicity in testis and epididymis of rats. Andrologia 48(4):393–401

CAS  PubMed 

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