Han SJ, Rolston JD, Jahangiri A et al (2014) Rathke’s cleft cysts: review of natural history and surgical outcomes. J Neurooncol 117:197–203. https://doi.org/10.1007/s11060-013-1272-6

Article  PubMed  Google Scholar 

Qian A, Zhou J, Zhang X et al (2022) Incidence and factors associated with the recurrence of rathke’s cleft cyst after surgery: A systematic review and meta-analysis. Front Surg 9:1065316. https://doi.org/10.3389/fsurg.2022.1065316

Article  PubMed  Google Scholar 

Shatri J, Ahmetgjekaj I (2018) Rathke’s cleft cyst or pituitary apoplexy: A case report and literature review. Open Access Maced J Med Sci 6:544–547. https://doi.org/10.3889/oamjms.2018.115

Article  PubMed  PubMed Central  Google Scholar 

Aho CJ, Liu C, Zelman V et al (2005) Surgical outcomes in 118 patients with Rathke cleft cysts. J Neurosurg 102:189–193. https://doi.org/10.3171/jns.2005.102.2.0189

Article  PubMed  Google Scholar 

Barkhoudarian G, Palejwala SK, Ansari S et al (2019) Rathke’s cleft cysts: a 6-year experience of surgery vs. observation with comparative volumetric analysis. Pituitary 22:362–371. https://doi.org/10.1007/s11102-019-00962-y

Article  PubMed  Google Scholar 

Chong GYC, Tan KCB, Lau EYF et al (2022) A study on clinical outcomes of rathke’s cleft cyst in patients managed conservatively. Pituitary 25:258–266. https://doi.org/10.1007/s11102-021-01194-9

Article  CAS  PubMed  Google Scholar 

Culver SA, Grober Y, Ornan DA et al (2015) A case for Conservative management: characterizing the natural history of radiographically diagnosed Rathke cleft cysts. J Clin Endocrinol Metab 100:3943–3948. https://doi.org/10.1210/jc.2015-2604

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dolovac RB, King J, Ovenden C et al (2025) Impact of Sella floor reconstruction on Rathke cleft cyst recurrence: a systematic review and meta-analysis. Pituitary 28:49. https://doi.org/10.1007/s11102-025-01521-4

Article  PubMed  PubMed Central  Google Scholar 

Kinoshita Y, Tominaga A, Usui S et al (2016) The long-term recurrence of rathke’s cleft cysts as predicted by histology but not by surgical procedure. J Neurosurg 125:1002–1007. https://doi.org/10.3171/2015.8.JNS151282

Article  PubMed  Google Scholar 

Limb R, King J (2021) Relationship between recurrence rates of rathke’s cleft cysts and surgical approaches to Sellar reconstruction. J Neurol Surg B Skull Base 82:e105–e111. https://doi.org/10.1055/s-0040-1701223

Article  PubMed  Google Scholar 

Nakase K, Nishimura F, Yokoyama S et al (2024) Long-term outcomes and potential predictive recurrence factors after endonasal endoscopic surgical treatment of symptomatic rathke’s cleft cysts. Neurosurg Rev 47:85. https://doi.org/10.1007/s10143-024-02322-2

Article  PubMed  Google Scholar 

Chotai S, Liu Y, Pan J et al (2015) Characteristics of rathke’s cleft cyst based on cyst location with a primary focus on recurrence after resection. J Neurosurg 122:1380–1389. https://doi.org/10.3171/2014.12.JNS14596

Article  PubMed  Google Scholar 

Hama S, Arita K, Nishisaka T et al (2002) Changes in the epithelium of Rathke cleft cyst associated with inflammation. J Neurosurg 96:209–216. https://doi.org/10.3171/jns.2002.96.2.0209

Article  PubMed  Google Scholar 

Ozoner B, Aydin S, Akgun MY et al (2019) Predictive factors for rathke’s cleft cyst consistency. World Neurosurg 128:e522–e530. https://doi.org/10.1016/j.wneu.2019.04.188

Article  PubMed  Google Scholar 

Potts P MB, Jahangiri A, Lamborn KR et al (2011) Suprasellar Rathke cleft cysts: clinical presentation and treatment outcomes. Neurosurgery 69:1058–1068. https://doi.org/10.1227/NEU.0b013e318228bcea. discussion 1068–1057

Zada G (2011) Rathke cleft cysts: a review of clinical and surgical management. Neurosurg Focus 31:E1. https://doi.org/10.3171/2011.5.FOCUS1183

Article  PubMed  Google Scholar 

Algattas HN, Gersey ZC, Fernandes Cabral D et al (2024) Endoscopic endonasal resection of Rathke cleft cysts: a single-institution analysis of 148 consecutive patients. J Neurosurg 141:1352–1362. https://doi.org/10.3171/2024.3.JNS232740

Article  PubMed  Google Scholar 

Lin M, Wedemeyer MA, Bradley D et al (2019) Long-term surgical outcomes following transsphenoidal surgery in patients with rathke’s cleft cysts. J Neurosurg 130:831–837. https://doi.org/10.3171/2017.11.JNS171498

Article  PubMed  Google Scholar 

Zhang X, Yang J, Huang Y et al (2021) Endoscopic endonasal resection of symptomatic Rathke cleft cysts: total resection or partial resection. Front Neurol 12:701177. https://doi.org/10.3389/fneur.2021.701177

Article  PubMed  PubMed Central  Google Scholar 

Yanase T, Tajima T, Katabami T et al (2016) Diagnosis and treatment [opinion]f adrenal [opinion]nsufficiency [opinion]ncluding adrenal crisis: a Japan endocrine society clinical [opinion]ractice guideline [Opinion]. Endocr J 63:765–784. https://doi.org/10.1507/endocrj.EJ16-0242

Article  PubMed  Google Scholar 

Tachibana O (2015) Rathke cleft cyst: review of pathology, imaging, and surgical outcome. Prog Neuro-Oncology 22:12–21

Google Scholar 

Alsavaf MB, Wu KC, Gosal JS et al (2023) Endoscopic endonasal marsupialization of Rathke cleft cysts: clinical outcomes and risk factors analysis of visual impairment, pituitary dysfunction, and CSF leak. Pituitary 26:696–707. https://doi.org/10.1007/s11102-023-01347-y

Article  PubMed  Google Scholar 

Hayes AG, Low JP, Shoung N et al (2024) Inflammation of adenohypophysis is commonly associated with headache in surgically managed rathke’s cleft cysts. Pituitary 28:9. https://doi.org/10.1007/s11102-024-01486-w

Article  PubMed  Google Scholar 

Langlois F, Manea A, Lim DST et al (2019) High prevalence of adrenal insufficiency at diagnosis and headache recovery in surgically resected rathke’s cleft cysts-a large retrospective single center study. Endocrine 63:463–469. https://doi.org/10.1007/s12020-018-1784-0

Article  CAS  PubMed  Google Scholar 

Montaser AS, Catalino MP, Laws ER, Professor (2021) Rathke’s gift to neurosurgery: the cyst, its diagnosis, surgical management, and outcomes. Pituitary 24:787–796. https://doi.org/10.1007/s11102-021-01155-2

Iwata T, Oshino S, Saitoh Y et al (2024) Appearance of fluid content in rathke’s cleft cyst is associated with clinical features and postoperative recurrence rates. Pituitary 27:287–293. https://doi.org/10.1007/s11102-024-01395-y

Article  PubMed  PubMed Central  Google Scholar 

Ogawa Y, Watanabe M, Tominaga T (2011) Prognostic factors of operated rathke’s cleft cysts with special reference to re-accumulation and recommended surgical strategy. Acta Neurochir (Wien) 153:2427–2433. https://doi.org/10.1007/s00701-011-1072-8. discussion 2433

Article  PubMed  Google Scholar 

Qi ST, Zhou J, Pan J et al (2012) Epithelial-mesenchymal transition and clinicopathological correlation in craniopharyngioma. Histopathology 61:711–725. https://doi.org/10.1111/j.1365-2559.2012.04297.x

Article  PubMed  Google Scholar 

Kino H, Akutsu H, Tanaka S et al (2020) Endoscopic endonasal cyst fenestration into the sphenoid sinus using the mucosa coupling method for symptomatic rathke’s cleft cyst: a novel method for maintaining cyst drainage to prevent recurrence. J Neurosurg 133:1710–1720. https://doi.org/10.3171/2019.8.JNS191103

Article  PubMed  Google Scholar 

Kuan EC et al (2017) Treatment outcomes of rathke’s cleft cysts managed with marsupialization. J Neurol Surg B Skull Base 78:112–115. https://doi.org/10.1055/s-0036-1585088

Article  PubMed  Google Scholar 

Ellens NR, Miller MC, Shafiq I et al (2021) Nonabsorbable intrasellar stent placement for recurrent Rathke cleft cyst: illustrative case. J Neurosurg Case Lessons 1:CASE2117. https://doi.org/10.3171/CASE2117

Article  PubMed  PubMed Central  Google Scholar 

Kuan EC, Trent MS, Luu NN et al (2019) Preventing restenosis of marsupialized Rathke cleft cysts using a nasoseptal flap lining. Laryngoscope 129:2258–2261. https://doi.org/10.1002/lary.28053

Article  PubMed  Google Scholar 

Ference EH, Badran KW, Kuan EC et al (2019) Bioabsorbable steroid eluting stents in the treatment of recurrent rathke’s cleft cyst. J Neurol Surg B Skull Base 80:505–510. https://doi.org/10.1055/s-0038-1675558