Association between skin temperature variability and sleep apnea severity: findings from a pilot study

Buijs RM, la Fleur SE, Wortel J et al (2003) The Suprachiasmatic nucleus balances sympathetic and parasympathetic output to peripheral organs through separate preautonomic neurons. J Comp Neurol 464:36–48. https://doi.org/10.1002/cne.10765

Article  PubMed  Google Scholar 

Kräuchi K, Deboer T (2013) Thermoregulation and sleep. In: Kushida CA (ed) Encyclopedia of sleep. Academic, Waltham, pp 490–493

Google Scholar 

Kräuchi K, Cajochen C, Werth E, Wirz-Justice A (1999) Warm feet promote the rapid onset of sleep. Nat Portfolio 401:36–37. https://doi.org/10.1038/43366

Article  Google Scholar 

Kräuchi K, Gasio PF, Vollenweider S et al (2008) Cold extremities and difficulties initiating sleep: evidence of co-morbidity from a random sample of a Swiss urban population. J Sleep Res 17:420–426. https://doi.org/10.1111/j.1365-2869.2008.00678.x

Article  PubMed  Google Scholar 

Kräuchi K, Cajochen C, Werth E, Wirz-Justice A (2000) Functional link between distal vasodilation and sleep-onset latency? American journal of Physiology-Regulatory. Integr Comp Physiol 278:R741–R748. https://doi.org/10.1152/ajpregu.2000.278.3.R741

Article  Google Scholar 

Cuesta M, Boudreau P, Cermakian N, Boivin DB (2017) Skin temperature rhythms in humans respond to changes in the timing of sleep and light. SAGE Publishing 32:257–273. https://doi.org/10.1177/0748730417702974

Article  CAS  Google Scholar 

Kräuchi K, Wirz-Justice A (1994) Circadian rhythm of heat production, heart rate, and skin and core temperature under unmasking conditions in men. Am J Physiology-Regulatory Integr Comp Physiol 267:R619–R864. https://doi.org/10.1152/ajpregu.1994.267.3.R819

Article  Google Scholar 

Savastano DM, Gorbach AM, Eden HS et al (2009) Adiposity and human regional body temperature. Am J Clin Nutr 90:1124–1131. https://doi.org/10.3945/ajcn.2009.27567

Article  CAS  PubMed  PubMed Central  Google Scholar 

Papaioannou VE, Chouvarda IG, Maglaveras NK, Pneumatikos IA (2012) Temperature variability analysis using wavelets and multiscale entropy in patients with systemic inflammatory response syndrome, sepsis, and septic shock. Crit Care 16:R51. https://doi.org/10.1186/cc11255

Article  PubMed  PubMed Central  Google Scholar 

Satti R, Abid N-U-H, Bottaro M et al (2019) The application of the extended poincaré plot in the analysis of physiological variabilities. Front Physiol 10:116. https://doi.org/10.3389/fphys.2019.00116

Article  PubMed  PubMed Central  Google Scholar 

Bottaro M, Abid NUH, El-Azizi I et al (2020) Skin temperature variability is an independent predictor of survival in patients with cirrhosis. Physiological Rep 8. https://doi.org/10.14814/phy2.14452

Abid N-U-H, Lum Cheng In T, Bottaro M et al (2024) Application of short-term analysis of skin temperature variability in prediction of survival in patients with cirrhosis. Front Netw Physiol 3. https://doi.org/10.3389/fnetp.2023.1291491

Tai Y, Obayashi K, Yamagami Y, Saeki K (2022) Inverse association of skin temperature with ambulatory blood pressure and the mediation of skin temperature in blood pressure responses to ambient temperature. Hypertension 79:1845–1855. https://doi.org/10.1161/HYPERTENSIONAHA.122.19190

Article  CAS  PubMed  Google Scholar 

Brooks TG, Lahens NF, Grant GR et al (2023) Diurnal rhythms of wrist temperature are associated with future disease risk in the UK biobank. Nat Commun 14:5172. https://doi.org/10.1038/s41467-023-40977-5

Article  CAS  PubMed  PubMed Central  Google Scholar 

Imadojemu VA, Gleeson K, Gray KS et al (2002) Obstructive apnea during sleep is associated with peripheral vasoconstriction. Am J Respir Crit Care Med 165:61–66. https://doi.org/10.1164/ajrccm.165.1.2009062

Article  PubMed  Google Scholar 

Martínez-Nicolás A, Guaita M, Santamaría J et al (2017) Circadian impairment of distal skin temperature rhythm in patients with sleep-disordered breathing: the effect of CPAP. https://doi.org/10.1093/sleep/zsx067. Oxford University Press 40:

DiCaro MV, Lei K, Yee B, Tak T (2024) The effects of obstructive sleep apnea on the cardiovascular system: A comprehensive review. J Clin Med 13:3223. https://doi.org/10.3390/jcm13113223

Article  CAS  PubMed  PubMed Central  Google Scholar 

Devulapally K, Pongonis R, Khayat R (2009) OSA: the new cardiovascular disease: part II: overview of cardiovascular diseases associated with obstructive sleep apnea. Heart Fail Rev 14:155–164. https://doi.org/10.1007/s10741-008-9101-2

Article  PubMed  Google Scholar 

Cao W, Luo J, Xiao Y (2020) A review of current tools used for evaluating the severity of obstructive sleep apnea. NSS 12:1023–1031. https://doi.org/10.2147/NSS.S275252

Article  Google Scholar 

Sleep Number (2025) Sleep number climate 360. https://www.sleepnumber.com/products/climate360. Accessed 13 Jun 2025

van Marken Lichtenbelt WD, Daanen HAM, Wouters L et al (2006) Evaluation of wireless determination of skin temperature using iButtons. Physiol Behav 88:489–497. https://doi.org/10.1016/j.physbeh.2006.04.026

Article  CAS  PubMed  Google Scholar 

iButtonLink Thermochron iButton In: Thermochron iButton. https://www.ibuttonlink.com/products/ds1922l. Accessed 13 Jun 2025

Berry RB, Gamaldo C, Harding S et al (2012) The AASM manual for the scoring of sleep and associated events: rules, terminology and technical specifications. American Academy of Sleep Medicine

Mbata G, Chukwuka J (2012) Obstructive sleep apnea hypopnea syndrome. Ann Med Health Sci Res 2:74–77. https://doi.org/10.4103/2141-9248.96943

Article  PubMed  PubMed Central  Google Scholar 

Dzierzewski JM, Dautovich ND, Rybarczyk B, Taylor SA (2020) Night-to-night fluctuations in sleep apnea severity: diagnostic and treatment implications. J Clin Sleep Med 16:539–544. https://doi.org/10.5664/jcsm.8272

Huikuri HV, Mäkikallio TH, Peng C-K et al (2000) Fractal correlation properties of R-R interval dynamics and mortality in patients with depressed left ventricular function after an acute myocardial infarction. Circulation 101:47–53. https://doi.org/10.1161/01.CIR.101.1.47

Article  CAS  PubMed  Google Scholar 

Benjamini Y, Hochberg Y (1995) Controlling the false discovery rate: A practical and powerful approach to multiple testing. J Roy Stat Soc: Ser B (Methodol) 57:289–300. https://doi.org/10.1111/j.2517-6161.1995.tb02031.x

Article  Google Scholar 

Baron RM, Kenny DA (1986) The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations. J Pers Soc Psychol 51:1173–1182. https://doi.org/10.1037//0022-3514.51.6.1173

CAS  PubMed  Google Scholar 

Sobel ME (1982) Asymptotic confidence intervals for indirect effects in structural equation models. Sociol Methodol 13:290–312. https://doi.org/10.2307/270723

Article  Google Scholar 

Garcia-Molina G, Winger T, Makaram N et al (2024) Unobtrusive skin temperature Estimation on a smart bed. Sensors 24:4882. https://doi.org/10.3390/s24154882

Article  PubMed  PubMed Central  Google Scholar 

Wang L, Wei D-H, Zhang J, Cao J (2022) Time under 90% oxygen saturation and systemic hypertension in patients with obstructive sleep apnea syndrome. Nat Sci Sleep 14:2123–2132. https://doi.org/10.2147/NSS.S388238

Article  CAS  PubMed  PubMed Central  Google Scholar 

Azarbarzin A, Sands SA, Stone KL et al (2019) The hypoxic burden of sleep Apnoea predicts cardiovascular disease-related mortality: the osteoporotic fractures in men study and the sleep heart health study. Eur Heart J 40:1149–1157. https://doi.org/10.1093/eurheartj/ehy624

Article  PubMed  Google Scholar 

Comments (0)

No login
gif