Puerarin Improves Cancer-Induced Bone Pain by Recovering Mitochondrial Dysfunction in the Spinal Cord

Abbott JA, Popescu GK (2022) Homecoming of the estranged GluD channels. Trends Neurosci 45:499–501

Article  CAS  PubMed  PubMed Central  Google Scholar 

Alimoradian A, Abbaszadeh F, Jorjani M (2024) Testosterone signaling pathways for reducing neuropathic pain in a rat model of spinothalamic tract lesion. Iran J Basic Med Sci 27:1417–1422

PubMed  PubMed Central  Google Scholar 

Cai Y, Xu J, Cheng Q (2021) Proto-oncogene tyrosine-protein kinase SRC (Src) Inhibition in microglia relieves neuroinflammation in neuropathic pain mouse models. Bioengineered 12:11390–11398

Article  CAS  PubMed  PubMed Central  Google Scholar 

Carrillo E, Gonzalez CU, Berka V, Jayaraman V (2021) Delta glutamate receptors are functional glycine- and -serine-gated cation channels in situ. Sci Adv 7:eabk2200

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen XJ, Wang L, Song XY (2020) Mitoquinone alleviates vincristine-induced neuropathic pain through inhibiting oxidative stress and apoptosis via the improvement of mitochondrial dysfunction. Biomed Pharmacother 125:110003

Article  CAS  PubMed  Google Scholar 

Gao W, Hu L, Zhang M, Liu S, Xu S, Chow VL, Chan JY, Wong TS (2022) Mitochondrial DHODH regulates hypoxia-inducible factor 1 expression in OTSCC. Am J Cancer Res 12:48–67

CAS  PubMed  PubMed Central  Google Scholar 

Grivennikova VG, Gladyshev GV, Vinogradov AD (2020) Deactivation of mitochondrial nadh:ubiquinone oxidoreductase (respiratory complex I): extrinsically affecting factors. Biochim Biophys Acta Bioenerg 1861:148207

Article  CAS  PubMed  Google Scholar 

Guedouari H, Ould Amer Y, Pichaud N, Hebert-Chatelain E (2021) Characterization of the interactome of c-Src within the mitochondrial matrix by proximity-dependent biotin identification. Mitochondrion 57:257–269

Article  CAS  PubMed  Google Scholar 

Guo C, Yue Y, Wang B, Chen S, Li D, Zhen F, Liu L, Zhu H, Xie M (2024) Anemoside B4 alleviates arthritis pain via suppressing ferroptosis-mediated inflammation. J Cell Mol Med 28, e18136

Habib MH, Schlögl M, Raza S, Chwistek M, Gulati A (2023) Interventional pain management in cancer patients-a scoping review. Ann Palliat Med 12:1198–1214

Article  PubMed  Google Scholar 

Hu YD, Wang ZD, Yue YF, Li D, Zhen SQ, Ding JQ, Meng W, Zhu HL, Xie M, Liu L (2024) Inhibition of HDAC6 alleviates cancer–induced bone pain by reducing the activation of NLRP3 inflammasome. Int J Mol Med 53:4

Article  CAS  PubMed  Google Scholar 

Huang D, Peng Y, Ma K, Qing X, Deng X, Li Z, Shao Z (2020) Puerarin relieved Compression-Induced apoptosis and mitochondrial dysfunction in human nucleus pulposus mesenchymal stem cells via the PI3K/Akt pathway. Stem Cells Int 7126914.

Ji RR, Nackley A, Huh Y, Terrando N, Maixner W (2018) Neuroinflammation and central sensitization in chronic and widespread pain. Anesthesiology 129:343–366

Article  PubMed  Google Scholar 

Jin S, Cinar R, Hu X, Lin Y, Luo G, Lovinger DM, Zhang Y, Zhang L (2021) Spinal astrocyte aldehyde dehydrogenase-2 mediates ethanol metabolism and analgesia in mice. Br J Anaesth 127:296–309

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kathiresan DS, Balasubramani R, Marudhachalam K, Jaiswal P, Ramesh N, Sureshbabu SG, Puthamohan VM, Vijayan M (2024) Role of mitochondrial dysfunctions in neurodegenerative disorders: advances in mitochondrial biology. Mol Neurobiol. https://doi.org/10.1007/s12035-024-04469-x

Article  PubMed  Google Scholar 

Li MY, Ding JQ, Tang Q, Hao MM, Wang BH, Wu J, Yu LZ, Jiao M, Luo BH, Xie M, Zhu HL (2019) SIRT1 activation by SRT1720 attenuates bone cancer pain via preventing Drp1-mediated mitochondrial fission. Biochim Biophys Acta Mol Basis Dis 1865:587–598

Article  CAS  PubMed  Google Scholar 

Li S, Xiong GJ, Huang N, Sheng ZH (2020) The cross-talk of energy sensing and mitochondrial anchoring sustains synaptic efficacy by maintaining presynaptic metabolism. Nat Metab 2:1077–1095

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li J, Shi X, Chen Z, Xu J, Zhao R, Liu Y, Wen Y, Chen L (2023) Aldehyde dehydrogenase 2 alleviates mitochondrial dysfunction by promoting PGC-1α-mediated biogenesis in acute kidney injury. Cell Death Dis 14:45

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu X, Huang R, Wan J (2023) Puerarin: a potential natural neuroprotective agent for neurological disorders. Biomed Pharmacother 162:114581

Article  CAS  PubMed  Google Scholar 

Lurette O, Guedouari H, Morris JL, Martín-Jiménez R, Robichaud JP, Hamel-Côté G, Khan M, Dauphinee N, Pichaud N, Prudent J, Hebert-Chatelain E (2022) Mitochondrial matrix-localized Src kinase regulates mitochondrial morphology. Cell Mol Life Sci 79:327

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mattar M, Umutoni F, Hassan MA, Wamburu MW, Turner R, Patton JS, Chen X, Lei W (2024) Chemotherapy-Induced peripheral neuropathy: A recent update on pathophysiology and treatment. Life (Basel) 14:991

CAS  PubMed  Google Scholar 

Meng F, Guo B, Ma YQ, Li KW, Niu FJ (2022) Puerarin: A review of its mechanisms of action and clinical studies in ophthalmology. Phytomedicine 107:154465

Article  CAS  PubMed  Google Scholar 

Nesterov S, Chesnokov Y, Kamyshinsky R, Panteleeva A, Lyamzaev K, Vasilov R, Yaguzhinsky L (2021) Ordered clusters of the complete oxidative phosphorylation system in cardiac mitochondria. Int J Mol Sci 22:1462

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ramirez MF, Strang A, Roland G, Lasala J, Owusu-Agyemang P (2023) Perioperative pain management and Cancer outcomes: A narrative review. J Pain Res 16:4181–4189

Article  CAS  PubMed  PubMed Central  Google Scholar 

Seike T, Chen CH, Mochly-Rosen D (2023) Impact of common ALDH2 inactivating mutation and alcohol consumption on alzheimer’s disease. Front Aging Neurosci 15:1223977

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sun B, Wang X, Ji Z, Wang M, Liao YP, Chang CH, Li R, Zhang H, Nel AE, Xia T (2015) NADPH Oxidase-Dependent NLRP3 Inflammasome Activation and its Important Role in Lung Fibrosis by Multiwalled Carbon Nanotubes. Small 11, 2087–2097

Tariq J, Townsend M, Parikh S, Bennett J (2024) Case report: severe hypertrophic cardiomyopathy in a female neonate caused by de Novo variant in NDUFB11. Eur Heart J Case Rep 8:ytae377

Article  PubMed  PubMed Central  Google Scholar 

Teckchandani S, Nagana Gowda GA, Raftery D, Curatolo M (2021) Metabolomics in chronic pain research. Eur J Pain 25:313–326

Article  PubMed  Google Scholar 

van den Ameele J, Fuge J, Pitceathly RDS, Berry S, McIntyre Z, Hanna MG, Lee M, Chinnery PF (2020) Chronic pain is common in mitochondrial disease. Neuromuscul Disord 30:413–419

Article  PubMed  PubMed Central  Google Scholar 

van der Vlist M, Raoof R, Willemen HLDM, Prado J, Versteeg S, Martin Gil C, Vos M, Lokhorst RE, Pasterkamp RJ, Kojima T, Karasuyama H, Khoury-Hanold W, Meyaard L, Eijkelkamp N (2022) Macrophages transfer mitochondria to sensory neurons to resolve inflammatory pain. Neuron 110:613–626e9

Article  PubMed  Google Scholar 

Wang L, Jiang W, Wang J, Xie Y, Wang W (2022) Puerarin inhibits FUNDC1-mediated mitochondrial autophagy and CSE-induced apoptosis of human bronchial epithelial cells by activating the PI3K/AKT/mTOR signaling pathway. Aging 14:1253–1264

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wen S, Wang L, Wang T, Xu M, Zhang W, Song R, Zou H, Gu J, Bian J, Yuan Y, Liu Z (2022) Puerarin alleviates cadmium-induced mitochondrial mass decrease by inhibiting PINK1-Parkin and Nix-mediated mitophagy in rat cortical neurons. Ecotoxicol Environ Saf 230:113127

Article  CAS  PubMed  Google Scholar 

Wijayanti IAS, Adnyana IMO, Widyadharma IPE, Wiratnaya IGE, Mahadewa TGB, Astawa INM (2024) Neuroinflammation mechanism unde

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