Marco Galluzzo and Marina Talamonti declare to have acted as speakers and/or consultants for AbbVie, Almirall, Eli-Lilly, Johnson & Johnson, LeoPharma, Novartis and Sanofi, outside the submitted work. Luca Bianchi declares to have acted as a speaker and/or consultant for AbbVie, Almirall, Eli-Lilly, Johnson & Johnson, LeoPharma, Novartis, Pfizer, Sanofi and UCB outside the submitted work. Lorenzo Marcelli declares no conflict of interests. Anna Balato has served as consultant and/or has received fees from: AbbVie, Almirall, Amgen,Boehringer Ingelheim, BMS, Leo-Pharma, Eli-Lilly, Johnson & Johnson, Novartis, Sanofi and UCB, outside the submitted work. Dario Buononato declares no conflict of interests. Nicoletta Bernardini and Nevena Skroza declare to have acted as speakers and/or consultants for AbbVie, Almirall, Eli-Lilly, Johnson & Johnson, LeoPharma, Novartis and UCB, outside the submitted work. Giacomo Caldarola has received consulting fees, honoraria and support for attending meetings from Abbvie, Eli-Lilly, Johnson & Johnson, UCB, Novartis and Leopharma. Clara De Simone has received support for consulting fees, honoraria and support for attending meetings from Abbvie, Eli-Lilly, Johnson & Johnson, UCB, Leopharma, Sanofi, Almirall, Boehringer Ingelheim and Bristol Myer Squibb. Eleonora De Luca declares no conflict of interests. Francesco Loconsole declares no conflict of interests. Edoardo Mortato declares no conflict of interests. Felice Primavera declares no conflict of interests. Viviana Lora declares no conflict of interests. Claudio Bonifati declares no conflict of interests. Matteo Megna declares to have acted as speakers and/or consultants for AbbVie, Amgen, Almirall, Eli-Lilly, Janssen-Cilag, LeoPharma, Novartis, Eli Lilly, UCB, outside the submitted work. Luca Potestio e Nello Tommasino declares no conflict of interests. Serena Lembo declares to have acted as speakers and/or consultants for Abbvie, Eli Lilly, Sanofi, Novartis, Janssen, LeoPharma outside the submitted work. Annunziata Raimondo declares to have acted as a speaker and/or consultant for Almirall, Janssen, Pfizer, Abbvie, and Novartis outside the submitted work. Maria Esposito has served as speaker/consultant for Abbvie, Amgen, Almirall, Eli Lilly, Janssen, Leopharma, Novartis, Pfizer, Sanofi, UCB. Maria Concetta Fargnoli has served as consultant/advisor, received speaker honoraria and/or grants, and/or is investigator for AMGEN, Almirall, Abbvie, Boehringer-Ingelheim, BMS, Galderma, Kyowa Kyrin, Incyte, LEO Pharma, Pierre Fabre, UCB, Lilly, Pfizer, Janssen, MSD, Novartis, Sanofi, Regeneron, Sun Pharma, Takeda. Anna Campanati has served as speaker/consultant for Abbvie, Almirall, Amgen, BMS, Difa-Cooper, Eli Lilly, Janssen, Leopharma, Mertz, Novartis, Pfizer, Sanofi, UCB. Tommaso Bianchelli has served as speaker/consultant for Abbvie, Almirall, Amgen, Janssen, Novartis, Pfizer, Sanofi, UCB. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed. Anna Campanati is an Editorial Board member of Dermatology and Therapy. Anna Campanati was not involved in the selection of peer reviewers for the manuscript.

The study was conducted in accordance with the 1975 Declaration of Helsinki ethical standards. According to Italian law, formal ethical committee approval is not required for this type of study.