Schenone M, Dančík V, Wagner BK, Clemons PA. Target identification and mechanism of action in chemical biology and drug discovery. Nat Chem Biol. 2013;2013:232–40.

Article  Google Scholar 

Stefanachi A, Leonetti F, Pisani L, Catto M, Carotti A. Coumarin: a natural, privileged and versatile scaffold for bioactive compounds. Molecules. 2018;23:250.

Article  PubMed  PubMed Central  Google Scholar 

Zhang L, Xu Z. Coumarin-containing hybrids and their anticancer activities. Eur J Med Chem. 2019;181:111587.

Article  CAS  PubMed  Google Scholar 

Rawat A, Vijaya Bhaskar Reddy A. Recent advances on anticancer activity of coumarin derivatives. Eur J Med Chem Reports. 2022;5:100038.

CAS  Google Scholar 

Wu XQ, Huang C, Jia YM, Song BA, Li J, Liu XH. Novel coumarin-dihydropyrazole thio-ethanone derivatives: design, synthesis and anticancer activity. Eur J Med Chem. 2014;74:717–25.

Article  CAS  PubMed  Google Scholar 

Steinhilber D, Fischer AS, Metzner J, Steinbrink SD, Roos J, Ruthardt M, et al. 5-Lipoxygenase: Underappreciated role of a pro-inflammatory enzyme in tumorigenesis. Front Pharmacol. 2010;1:143.

Article  CAS  PubMed  PubMed Central  Google Scholar 

van Duin D, Paterson DL. Multidrug-resistant bacteria in the community: trends and lessons learned. Infect Dis Clin North Am. 2016;30:377–90.

Article  PubMed  PubMed Central  Google Scholar 

Patil SA, Nesaragi AR, Rodríguez-Berrios RR, Hampton SM, Bugarin A, Patil SA. Coumarin triazoles as potential antimicrobial agents. Antibiot. 2023;12:160.

Article  CAS  Google Scholar 

Cheke RS, Patel HM, Patil VM, Ansari IA, Ambhore JP, Shinde SD, et al. Molecular insights into coumarin analogues as antimicrobial agents: Recent developments in drug discovery. Antibiot. 2022;11:566.

Article  CAS  Google Scholar 

Strzelecka M, Świątek P. 1,2,4-Triazoles as important antibacterial agents. Pharmaceuticals (Basel). 2021;14:224. Mar 7

Article  CAS  PubMed  Google Scholar 

Bozorov K, Zhao J, Aisa HA. 1,2,3-Triazole-containing hybrids as leads in medicinal chemistry: a recent overview. Bioorg Med Chem. 2019;27:3511–31.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hein JE, Fokin VV. Copper-catalyzed azide–alkyne cycloaddition (CuAAC) and beyond: New reactivity of copper(i) acetylides. Chem Soc Rev. 2010;39:1302–15.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Irby D, Du C, Li F. Lipid–drug conjugate for enhancing drug delivery. Mol Pharm. 2017;14:1325–38.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tiwari VK, Mishra BB, Mishra KB, Mishra N, Singh AS, Chen X. Cu-catalyzed click reaction in carbohydrate chemistry. Chem Rev. 2016;116:3086–240.

Article  CAS  PubMed  Google Scholar 

Kumar D, Mishra KB, Mishra BB, Mondal S, Tiwari VK. Click chemistry inspired highly facile synthesis of triazolyl ethisterone glycoconjugates. Steroids. 2014;80:71–79.

Article  CAS  PubMed  Google Scholar 

Mishra KB, Mishra BB, Tiwari VK. Efficient synthesis of ethisterone glycoconjugate via bis-triazole linkage. Carbohydr Res. 2014;399:2–7.

Article  CAS  PubMed  Google Scholar 

Kaper JB, Nataro JP, Mobley HLT. Pathogenic Escherichia coli. Nature Reviews Microbiology. 2004;2:123–40.

Article  CAS  PubMed  Google Scholar 

Ramos-Esteban JC, Servat JJ, Tauber S, Bia F. Bacillus megaterium delayed onset lamellar keratitis after LASIK. J Refract Surg. 2006;22:309–12.

Article  PubMed  Google Scholar 

Duncan KO, Smith TL. Primary cutaneous infection with Bacillus megaterium mimicking cutaneous anthrax. J Am Acad Dermatol. 2011;65:e60–1.

Article  PubMed  Google Scholar 

Guo Fu-Ping, Fan Hong-Wei, Liu Zheng-Yin, Yang Qi-Wei, Li Yi-Jia, Li Tai-Sheng. Brain abscess caused by Bacillus megaterium in an adult patient. Chin Med J (Engl). 2015;128:1552–4.

Article  PubMed  Google Scholar 

Aragaw WW, Lee BM, Yang X, Zimmerman MD, Gengenbacher M, Dartois V, et al. Potency boost of a mycobacterium tuberculosis dihydrofolate reductase inhibitor by multienzyme F420H2-dependent reduction. Proc Natl Acad Sci USA. 2021;118:e2025172118.

Article  CAS  PubMed  PubMed Central  Google Scholar 

McClendon AK, Osheroff N. DNA topoisomerase ii, genotoxicity, and cancer. Mutat. Res. - Fundam. Mol Mech Mutagen. 2007;623:83–97.

Article  CAS  Google Scholar 

Boonthaworn K, Hengphasatporn K, Shigeta Y, Chavasiri W, Rungrotmongkol T, Ounjai P. In silico screening of chalcones and flavonoids as potential inhibitors against yellow head virus 3C-like protease. PeerJ. 2023;11:e15086.

Article  PubMed  PubMed Central  Google Scholar 

Li R, Sirawaraporn R, Chitnumsub P, Sirawaraporn W, Wooden J, Athappilly F, et al. Three-dimensional structure of M. tuberculosis dihydrofolate reductase reveals opportunities for the design of novel tuberculosis drugs. J Mol Biol. 2000;295:307–23.

Article  CAS  PubMed  Google Scholar 

Al-Thubiani ASA, Maher YA, Fathi A, Abourehab M, Alarjah M, Khan M, et al. Identification and characterization of a novel antimicrobial peptide compound produced by bacillus megaterium strain isolated from oral microflora. Saudi Pharm J. 2018;26:1089–97.

Article  PubMed  PubMed Central  Google Scholar 

https://www.rcsb.org/structure/1DF7.

Shoemaker RH. The NCI60 human tumour cell line anticancer drug screen. Nat Rev Cancer. 2006;6:813–23.

Article  CAS  PubMed  Google Scholar