Fabricating Composite Cell Sheets for Wound Healing: Cell Sheets Based on the Communication Between BMSCs and HFSCs Facilitate Full-Thickness Cutaneous Wound Healing

Yu J, Wang M, Tai H, Cheng N. Cell sheet composed of adipose-derived stem cells demonstrates enhanced skin wound healing with reduced scar formation. Acta Biomater. 2018;77:191–200.

Article  CAS  PubMed  Google Scholar 

Stadelmann W, Digenis A, Tobin G. Physiology and healing dynamics of chronic cutaneous wounds. Am J Surg. 1998;176:26S-38S.

Article  CAS  PubMed  Google Scholar 

Guo R, Wan F, Morimatsu M, Xu Q, Feng T, Yang H, Gong Y, Ma S, Chang Y, Zhang S, Jiang Y, Wang H, Chang D, Zhang H, Ling Y, Lan F. Cell sheet formation enhances the therapeutic effects of human umbilical cord mesenchymal stem cells on myocardial infarction as a bioactive material. Bioact mater. 2021;6(9):2999–3012.

CAS  PubMed  PubMed Central  Google Scholar 

Kobayashi J, Kikuchi A, Aoyagi T, Okano T. Cell sheet tissue engineering: cell sheet preparation, harvesting/manipulation, and transplantation. J Biomed Mater Res Part A. 2019;107(5):955–67.

Article  CAS  Google Scholar 

Matsuura K, Utoh R, Nagase K, Okano T. Cell sheet approach for tissue engineering and regenerative medicine. J Controll Release: Off J Controll Release Soc. 2014;190:228–39.

Article  CAS  Google Scholar 

Yamato M, Utsumi M, Kushida A, Konno C, Kikuchi A, Okano T. Thermo-responsive culture dishes allow the intact harvest of multilayered keratinocyte sheets without dispase by reducing temperature. Tissue Eng. 2001;7(4):473–80.

Article  CAS  PubMed  Google Scholar 

Discher DE, Mooney DJ, Zandstra PW. Growth factors, matrices, and forces combine and control stem cells. Science. 2009;324(5935):1673–7.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zou G, Zhang J, Yang Q, Wang X, Sun P. hAMSC sheet promotes repair of rabbit osteochondral defects. Stem cells Int. 2022;2022:3967722.

Article  PubMed  PubMed Central  Google Scholar 

Zhang H, Liu S, Zhu B, Xu Q, Ding Y, Jin Y. Correction: composite cell sheet for periodontal regeneration: crosstalk between different types of MSCS in cell sheet facilitates complex periodontal-like tissue regeneration. Stem Cell Res Ther. 2022;13(1):363.

Article  PubMed  PubMed Central  Google Scholar 

Zhao Z, Sun Y, Qiao Q, Zhang L, Xie X, Weir MD, Bai Y. Human periodontal ligament stem cell and umbilical vein endothelial cell co-culture to prevascularize scaffolds for angiogenic and osteogenic tissue engineering. Int J Mol Sci. 2021;22(22):12363.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dariima T, Jin G, Lee E, Wall I, Kim H. Cooperation between osteoblastic cells and endothelial cells enhances their phenotypic responses and improves osteoblast function. Biotech Lett. 2013;35(7):1135–43.

Article  CAS  Google Scholar 

Zhang H, Zhou Y, Zhang W, Wang K, Xu L, Ma H, Deng Y. Construction of vascularized tissue-engineered bone with a double-cell sheet complex. Acta Biomater. 2018;77:212–27.

Article  CAS  PubMed  Google Scholar 

Zhu Z, Guo L, Yeltai N, Xu H, Zhang Y. Chemokine (C–C motif) ligand 2-enhanced adipogenesis and angiogenesis of human adipose-derived stem cell and human umbilical vein endothelial cell co-culture system in adipose tissue engineering. J Tissue Eng Regen Med. 2022;16(2):163–76.

Article  CAS  PubMed  Google Scholar 

Lee J, Shin D, Roh J. Use of a pre-vascularised oral mucosal cell sheet for promoting cutaneous burn wound healing. Theranostics. 2018;8(20):5703–12.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Caplan A. Adult mesenchymal stem cells for tissue engineering versus regenerative medicine. J Cell Physiol. 2007;213(2):341–7.

Article  CAS  PubMed  Google Scholar 

Chen L, Xing Q, Zhai Q, Tahtinen M, Zhou F, Chen L, Xu Y, Qi S, Zhao F. Pre-vascularization enhances therapeutic effects of human mesenchymal stem cell sheets in full thickness skin wound repair. Theranostics. 2017;7(1):117–31.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Fan Z, Xie X, Zhu S, Liao X, Yin Z, Zhang Y, Liu F. Novel pre-vascularized tissue-engineered dermis based on stem cell sheet technique used for dermis-defect healing. Regen Biomater. 2020;7(6):627–38.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Huang Y, Gou M, Da L, Zhang W, Xie H. Mesenchymal stem cells for chronic wound healing: current status of preclinical and clinical studies, tissue engineering. Part B Rev. 2020;26(6):555–70.

CAS  Google Scholar 

Gao Q, Wang L, Wang S, Huang B, Jing Y, Su J. Bone marrow mesenchymal stromal cells: identification. Classif Differ Front cell Dev Biol. 2021;9:787118.

Article  Google Scholar 

Li B, Hu W, Ma K, Zhang C, Fu X. Are hair follicle stem cells promising candidates for wound healing? Expert Opin Biol Ther. 2019;19(2):119–28.

Article  CAS  PubMed  Google Scholar 

Li H, Ziemer M, Stojanovic I, Saksida T, Maksimovic-Ivanic D, Mijatovic S, Djmura G, Gajic D, Koprivica I, Krajnovic T, Draca D, Simon J, Lethaus B, Savkovic V. Mesenchymal stem cells from mouse hair follicles reduce hypertrophic scarring in a murine wound healing model. Stem cell Rev Rep. 2022;18(6):2028–44.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu F, Zhou H, Du W, Huang X, Zheng X, Zhang C, Hu H, Wang J, Quan R. Hair follicle stem cells combined with human allogeneic acellular amniotic membrane for repair of full thickness skin defects in nude mice. J Tissue Eng Regen Med. 2020;14(5):723–35.

Article  CAS  PubMed  Google Scholar 

Aamar E, Laron EA, Asaad W, Harshuk-Shabso S, Enshell-Seijffers D. Hair-follicle mesenchymal stem cell activity during homeostasis and wound healing. J Investig Dermatol. 2021;141(12):2797–807.

Article  CAS  PubMed  Google Scholar 

Li G, Tang X, Zhang S, Jin M, Wang M, Deng Z, Liu Z, Qian M, Shi W, Wang Z, Xie H, Li J, Liu B. SIRT7 activates quiescent hair follicle stem cells to ensure hair growth in mice. EMBO J. 2020;39(18):e104365.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang N, Liu H, Li X, Zhang Q, Chen M, Jin Y, Deng X. Activities of MSCs derived from transgenic mice seeded on adm scaffolds in wound healing and assessment by advanced optical techniques. Cell Physiol Biochem: Int J Exp cell Physiol, Biochem, Pharmacol. 2017;42(2):623–39.

Article  CAS  Google Scholar 

Zhang Y, Jiang W, Kong L, Fu J, Zhang Q, Liu H. PLGA@IL-8 nanoparticles-loaded acellular dermal matrix as a delivery system for exogenous MSCs in diabetic wound healing. Int J Biol Macromol. 2023;224:688–98.

Article  CAS  PubMed  Google Scholar 

Jiang D, Scharffetter-Kochanek K. Mesenchymal stem cells adaptively respond to environmental cues thereby improving granulation tissue formation and wound healing. Front cell Dev Biol. 2020;8:697.

Article  PubMed  PubMed Central  Google Scholar 

Koo M, Hee Hong S, Hee Lee M, Kwon B, Mi Seon G, Sung Kim M, Kim D, Chang Nam K, Park J. Effective stacking and transplantation of stem cell sheets using exogenous ROS-producing film for accelerated wound healing. Acta Biomater. 2019;95:418–26.

Article  CAS  PubMed  Google Scholar 

Tamama K, Kawasaki H, Wells A. Epidermal growth factor (egf) treatment on multipotential stromal cells (MSCs). Possible enhancement of therapeutic potential of MSC. J Biomed Biotechnol. 2010;2010:795385.

Article  PubMed  PubMed Central  Google Scholar 

Wang M, Xu X, Lei X, Tan J, Xie H. Mesenchymal stem cell-based therapy for burn wound healing. Burns trauma. 2021;9:tkab002.

Article  PubMed  PubMed Central  Google Scholar 

Cheng X, Yu Z, Song Y, Zhang Y, Du J, Su Y, Ma X. Hair follicle bulge-derived stem cells promote tissue regeneration during skin expansion. Biomed Pharmacother. 2020;132:110805.

Article  CAS  PubMed  Google Scholar 

Wang Y, Liu Z, Zhao Q, Sun T, Ma K, Fu X. Future application of hair follicle stem cells: capable in differentiation into sweat gland cells. Chin Med J. 2013;126(18):3545–52.

CAS  PubMed  Google Scholar 

Ito M, Liu Y, Yang Z, Nguyen J, Liang F, Morris R, Cotsarelis G. Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis. Nat Med. 2005;11(12):1351–4.

Article  CAS  PubMed  Google Scholar 

Heidari F, Yari A, Rasoolijazi H, Soleimani M, Dehpoor A, Sajedi N, Joulai Veijouye S, Nobakht M. Bulge hair follicle stem cells accelerate cutaneous wound healing in rats. Wounds Compend Clin Res Pract. 2016;28(4):132–41.

Google Scholar 

Hoffman R, Amoh Y. Hair follicle-associated pluripotent(HAP) stem cells. Prog Mol Biol Transl Sci. 2018;160:23–8.

Article  CAS  PubMed  Google Scholar 

Wang B, Liu X, Liu Z, Wang Y, Han X, Lian A, Mu Y, Jin M, Liu J. Human hair follicle-derived mesenchymal stem cells: isolation, expansion, and differentiation. World J stem cells. 2020;12(6):462–70.

Article  PubMed  PubMed Central 

Comments (0)

No login
gif