Zhu HX, Lou WW, Jiang YM, Ciobanu A, Fang CX, Liu CY et al (2025) Histamine Modulation of the Basal Ganglia Circuitry in the Motor Symptoms of Parkinson’s Disease. CNS Neurosci Ther 31(2):e70308

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zheng C, Wu L, Luo L, Cai J, Huang Z, Tian K (2025) Therapeutic Effects and Mechanisms of Icaritin in Parkinson’s Disease. Curr Pharm Des 31(25):1983–1989

Article  CAS  PubMed  Google Scholar 

Zhao R, Jia N, Wu S, Wen J, Huang Y, Zhao C et al (2025) Therapeutic potential and limitation of condensed and hydrolyzed tannins in Parkinson’s disease. Int J Biol Macromol 307(Pt 1):141814

Article  CAS  PubMed  Google Scholar 

Zhang M, Lin Y, Wei H, Ju Q, Gao T, Zhang Y et al (2025) The membrane receptor CD44: roles in neurodegenerative diseases. Expert Opin Ther Targets. :1–1029(10):717-726

Wang Y, Zhou Y, Tian H, Li Q, Chen Y, Wang L et al (2025) NF-κB signalling pathway in neurodegenerative diseases: Acupuncture as a potential therapeutic approach. Brain Res 1865:149893

Article  CAS  PubMed  Google Scholar 

Servi R, Akkoç RF, Aksu F, Servi S (2025) Therapeutic potential of enzymes, neurosteroids, and synthetic steroids in neurodegenerative disorders: A critical review. J Steroid Biochem Mol Biol 251:106766

Article  CAS  PubMed  Google Scholar 

He J, Zhu G, Wang G, Zhang F (2020) Oxidative Stress and Neuroinflammation Potentiate Each Other to Promote Progression of Dopamine Neurodegeneration. Oxid Med Cell Longev 2020:6137521

Article  PubMed  PubMed Central  Google Scholar 

Elfil M, Kamel S, Kandil M, Koo BB, Schaefer SM (2020) Implications of the Gut Microbiome in Parkinson’s Disease. Mov Disord 35(6):921–933

Article  CAS  PubMed  Google Scholar 

Dragunow M (2020) Human Brain Neuropharmacology: A Platform for Translational Neuroscience. Trends Pharmacol Sci 41(11):777–792

Article  CAS  PubMed  Google Scholar 

Le Naour J, Galluzzi L, Zitvogel L, Kroemer G, Vacchelli E (2020) Trial watch: TLR3 agonists in cancer therapy. Oncoimmunology 9(1):1771143

Article  PubMed  PubMed Central  Google Scholar 

Kumar A, Behl T, Jamwal S, Kaur I, Sood A, Kumar P (2020) Exploring the molecular approach of COX and LOX in Alzheimer’s and Parkinson’s disorder. Mol Biol Rep 47(12):9895–9912

Article  CAS  PubMed  Google Scholar 

Imagawa A, Tachibana M (2020) Fulminant type 1 diabetes: recent research progress and future prospects. Diabetol Int 11(4):336–341

Article  PubMed  PubMed Central  Google Scholar 

Guan Y, Han F (2020) Key Mechanisms and Potential Targets of the NLRP3 Inflammasome in Neurodegenerative Diseases. Front Integr Neurosci 14:37

Article  CAS  PubMed  PubMed Central  Google Scholar 

Runtsch MC, Ferrara G, Angiari S (2021) Metabolic determinants of leukocyte pathogenicity in neurological diseases. J Neurochem 158(1):36–58

Article  CAS  PubMed  Google Scholar 

Mulica P, Grünewald A, Pereira SL (2021) Astrocyte-Neuron Metabolic Crosstalk in Neurodegeneration: A Mitochondrial Perspective. Front Endocrinol (Lausanne) 12:668517

Article  PubMed  PubMed Central  Google Scholar 

Zhu Y, Guo X, Zhou Y, Zhang D, Yi X, Wang H et al (2021) Levels of serum IL6, TNF-α and sLAG3 are changed and correlated with clinical characteristics in Parkinson’s disease patients: A case-control study. Neurol Asia 26(4):709–714

Article  Google Scholar 

Gupta V, Garg RK, Khattri S (2016) Levels of IL-8 and TNF-alpha decrease in Parkinson’s disease. Neurol Res 38(2):98–102

Article  CAS  PubMed  Google Scholar 

Kouchaki E, Kakhaki RD, Tamtaji OR, Dadgostar E, Behnam M, Nikoueinejad H et al (2018) Increased serum levels of TNF-alpha and decreased serum levels of IL-27 in patients with Parkinson disease and their correlation with disease severity. Clin Neurol Neurosurg 166:76–79

Article  PubMed  Google Scholar 

Fu J, Chen S, Liu J, Yang J, Ou R, Zhang L et al (2023) Serum inflammatory cytokines levels and the correlation analyses in Parkinson’s disease. Front Cell Dev Biol 11:1104393

Article  PubMed  PubMed Central  Google Scholar 

El-Kattan MM, Rashed LA, Shazly SR, Ismail RS (2022) Relation of serum level of tumor necrosis factor-alpha to cognitive functions in patients with Parkinson’s disease. Egypt J Neurol Psychiatry Neurosurg. ;58(1) :28-31

Scalzo P, Kummer A, Cardoso F, Teixeira AL (2009) Increased serum levels of soluble tumor necrosis factor-alpha receptor-1 in patients with Parkinson’s disease. J Neuroimmunol 216(1–2):122–125

Article  CAS  PubMed  Google Scholar 

Yuan Y, Zhang Y, Cheng Y, Hou Y, Huang Z, Ma J et al (2022) Cerebrospinal Fluid TNF-alpha and Orexin in Patients With Parkinson’s Disease and Rapid Eye Movement Sleep Behavior Disorder. Front Neurol 13:826013

Article  PubMed  PubMed Central  Google Scholar 

Xiromerisiou G, Marogianni C, Lampropoulos IC, Dardiotis E, Speletas M, Ntavaroukas P et al (2022) Peripheral Inflammatory Markers TNF-alpha and CCL2 Revisited: Association with Parkinson’s Disease Severity. Int J Mol Sci. ;24(1) :69–71

Varshney V, Kumar A, Parashar V, Kumar A, Goyal A, Garabadu D (2024) Therapeutic Potential of Capsaicin in Various Neurodegenerative Diseases with Special Focus on Nrf2 Signaling. Curr Pharm Biotechnol 25(13):1693–1707

Article  PubMed  Google Scholar 

Haupt M, Bähr M, Doeppner TR (2021) Lithium beyond psychiatric indications: the reincarnation of a new old drug. Neural Regen Res 16(12):2383–2387

Article  CAS  PubMed  PubMed Central  Google Scholar 

Heidari A, Yazdanpanah N, Rezaei N (2022) The role of Toll-like receptors and neuroinflammation in Parkinson’s disease. J Neuroinflammation 19(1):135

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mahakalakar N, Mohariya G, Taksande B, Kotagale N, Umekar M, Vinchurney M (2025) Nattokinase as a potential therapeutic agent for preventing blood-brain barrier dysfunction in neurodegenerative disorders. Brain Res 1849:149352

Article  CAS  PubMed  Google Scholar 

Kaspute G, Ramanavicius A, Prentice U (2025) Natural drug delivery systems for the treatment of neurodegenerative diseases. Mol Biol Rep 52(1):217

Article  CAS  PubMed  Google Scholar 

Sharif A, Mamo J, Lam V, Al-Salami H, Mooranian A, Watts GF et al (2024) The therapeutic potential of probucol and probucol analogues in neurodegenerative diseases. Transl Neurodegener 13(1):6

Article  CAS  PubMed  PubMed Central  Google Scholar 

Grandi R, Gulati V, Islam MS, Ekpo O, Chitranshi N (2025) Investigating the impact of resveratrol and quercetin on glymphatic function, blood-brain barrier, and neuroglial health: A systematic review. Brain Res 1870:150046

Article  PubMed  Google Scholar 

Fu L, Luo T, Hao Z, Pan Y, Xin W, Zhang L et al (2025) Exploring novel roles of lipid droplets and lipid metabolism in regulating inflammation and blood-brain barrier function in neurological diseases. Front Neurosci 19:1603292

Article  PubMed  PubMed Central  Google Scholar 

Huang X, Gu R, Li Z, Wang F (2025) Igniting Cold Tumors: Multi-Omics-Driven Strategies to Overcome Immune Evasion and Restore Immune Surveillance. Oncol Res 33(10):2857–2902

Article  PubMed  PubMed Central  Google Scholar 

Kwok AJ, Lu J, Huang J, Ip BY, Mok VCT, Lai HM et al (2024) High-resolution omics of vascular ageing and inflammatory pathways in neurodegeneration. Semin Cell Dev Biol 155(Pt C):30–49

Article  CAS  PubMed