Prognostic Significance of Radiological Adjacent Organ Invasion in Resectable Left-Sided Pancreatic Cancer

Rawla P, Sunkara T, Gaduputi V. Epidemiology of pancreatic cancer: Global trends, etiology and risk factors. World J Oncol. 2019;10(1):10–27.

Article  PubMed  PubMed Central  Google Scholar 

Bengtsson A, Andersson R, Ansari D. The actual 5-year survivors of pancreatic ductal adenocarcinoma based on real-world data. Sci Rep. 2020;10(1):16425.

Article  PubMed  PubMed Central  Google Scholar 

National Comprehensive Cancer Network. NCCN Clinical Practice Guidelines in Oncology. Pancreatic adenocarcinoma.version 1.2025 [Internet]. [cited 2024 Jan 25]. Available from: https://www.nccn.org/professionals/physician_gls/pdf/pancreatic.pdf

Japan Pancreas Society. Clinical Practice Guideline for Pancreatic Cancer 2022 [Internet]. [cited 2024 Feb 20]. http://www.suizou.org/pdf/pancreatic_cancer_cpg-2022.pdf

Crippa S, Cirocchi R, Maisonneuve P, Partelli S, Pergolini I, Tamburrino D, et al. Systematic review and meta-analysis of prognostic role of splenic vessels infiltration in resectable pancreatic cancer. Eur J Surg Oncol. 2018;44(1):24–30.

Article  PubMed  Google Scholar 

Mizumoto T, Toyama H, Asari S, Terai S, Mukubo H, Yamashita H, et al. Pathological and radiological splenic vein involvement are predictors of poor prognosis and early liver metastasis after surgery in patients with pancreatic adenocarcinoma of the body and tail. Ann Surg Oncol. 2018;25(3):638–46.

Article  PubMed  Google Scholar 

Hyun JJ, Rose JB, Alseidi AA, Biehl TR, Helton S, Coy DL, et al. Significance of radiographic splenic vessel involvement in the pancreatic ductal adenocarcinoma of the body and tail of the gland. J Surg Oncol. 2019;120(2):262–9.

Article  PubMed  Google Scholar 

Kawai M, Hirono S, Okada K-I, Miyazawa M, Kitahata Y, Kobayashi R, et al. Radiographic splenic artery involvement is a poor prognostic factor in upfront surgery for patients with resectable pancreatic body and tail cancer. Ann Surg Oncol. 2021;28(3):1521–32.

Article  PubMed  Google Scholar 

Kang JS, Choi YJ, Byun Y, Han Y, Kim JH, Lee JM, et al. Radiological tumour invasion of splenic artery or vein in patients with pancreatic body or tail adenocarcinoma and effect on recurrence and survival. Br J Surg. 2021;109(1):105–13.

Article  PubMed  Google Scholar 

Kitamura K, Esaki M, Sone M, Sugawara S, Hiraoka N, Nara S, et al. Prognostic impact of radiological splenic artery involvement in pancreatic ductal adenocarcinoma of the body and tail. Ann Surg Oncol. 2022;29(11):7047–58.

Article  PubMed  Google Scholar 

Motoi F, Kosuge T, Ueno H, Yamaue H, Satoi S, Sho M, et al. Randomized phase II/III trial of neoadjuvant chemotherapy with gemcitabine and S-1 versus upfront surgery for resectable pancreatic cancer (Prep-02/JSAP05). Jpn J Clin Oncol. 2019;49(2):190–4.

Article  PubMed  Google Scholar 

Ohgi K, Sugiura T, Okamura Y, Ashida R, Yamada M, Otsuka S, et al. Long-term adjuvant chemotherapy after resection for pancreatic cancer patients with positive peritoneal lavage cytology. Langenbecks Arch Surg. 2023;408(1):165.

Article  PubMed  Google Scholar 

Ishida M, Fujii T, Kishiwada M, Shibuya K, Satoi S, Ueno M, et al. Japanese classification of pancreatic carcinoma by the Japan Pancreas Society: 8th edition. J Hepatobiliary Pancreat Sci. 2024;31(11):755–68

Brierley JD. TNM classification of malignant tumours, 8th ed. 2017.

Yamada M, Sugiura T, Okamura Y, Ito T, Yamamoto Y, Ashida R, et al. Microscopic venous invasion in pancreatic cancer. Ann Surg Oncol. 2018;25(4):1043–51.

Article  PubMed  Google Scholar 

Kubo H, Ohgi K, Sugiura T, Ashida R, Yamada M, Otsuka S, et al. The association between neoadjuvant therapy and pathological outcomes in pancreatic cancer patients after resection: prognostic significance of microscopic venous invasion. Ann Surg Oncol. 2022;29(8):4992–5002.

Article  PubMed  Google Scholar 

Oettle H, Neuhaus P, Hochhaus A, Hartmann JT, Gellert K, Ridwelski K, et al. Adjuvant chemotherapy with gemcitabine and long-term outcomes among patients with resected pancreatic cancer: the CONKO-001 randomized trial. JAMA. 2013;310(14):1473–81.

Article  CAS  PubMed  Google Scholar 

Uesaka K, Boku N, Fukutomi A, Okamura Y, Konishi M, Matsumoto I, et al. Adjuvant chemotherapy of S-1 versus gemcitabine for resected pancreatic cancer: a phase 3, open-label, randomised, non-inferiority trial (JASPAC 01). Lancet. 2016;388(10041):248–57.

Article  CAS  PubMed  Google Scholar 

Kanda Y. Investigation of the freely available easy-to-use software “EZR” for medical statistics. Bone Marrow Transplant. 2013;48(3):452–8.

Article  CAS  PubMed  Google Scholar 

Avula LR, Hagerty B, Alewine C. Molecular mediators of peritoneal metastasis in pancreatic cancer. Cancer Metastasis Rev. 2020;39(4):1223–43.

Article  PubMed  PubMed Central  Google Scholar 

Kanda M, Kodera Y. Molecular mechanisms of peritoneal dissemination in gastric cancer. World J Gastroenterol. 2016;22(30):6829–40.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sahakyan MA, Kazaryan AM, Rawashdeh M, Fuks D, Shmavonyan M, Haugvik S-P, et al. Laparoscopic distal pancreatectomy for pancreatic ductal adenocarcinoma: results of a multicenter cohort study on 196 patients. Surg Endosc. 2016;30(8):3409–18.

Article  PubMed  Google Scholar 

Hartwig W, Gluth A, Hinz U, Koliogiannis D, Strobel O, Hackert T, et al. Outcomes after extended pancreatectomy in patients with borderline resectable and locally advanced pancreatic cancer: Extended pancreatectomy in borderline resectable and locally advanced pancreatic cancer. Br J Surg. 2016;103(12):1683–94.

Article  CAS  PubMed  Google Scholar 

de Rooij T, Tol JA, van Eijck CH, Boerma D, Bonsing BA, Bosscha K, et al. Outcomes of distal pancreatectomy for pancreatic ductal adenocarcinoma in the Netherlands: A nationwide retrospective analysis. Ann Surg Oncol. 2016;23(2):585–91.

Article  PubMed  Google Scholar 

Sahakyan MA, Kleive D, Kazaryan AM, Aghayan DL, Ignjatovic D, Labori KJ, et al. Extended laparoscopic distal pancreatectomy for adenocarcinoma in the body and tail of the pancreas: a single-center experience. Langenbecks Arch Surg. 2018;403(8):941–8.

Article  PubMed  Google Scholar 

Ferrari C, Leon P, Falconi M, Boggi U, Piardi T, Sulpice L, et al. Multi-visceral resection for left-sided pancreatic ductal adenocarcinoma: a multicenter retrospective analysis from European countries. Langenbecks Arch Surg. 2023;408(1):386.

Article  PubMed  Google Scholar 

Comments (0)

No login
gif