Total Neoadjuvant Therapy for Rectal Cancer: Current Status and Future Directions

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• Cercek A, Roxburgh CSD, Strombom P, Smith JJ, Temple LKF, Nash GM, et al. Adoption of total neoadjuvant therapy for locally advanced rectal cancer. JAMA Oncol. 2018;4(6):e180071. The largest retrospective review demonstrating improved tolerability and response rates for TNT compared to traditional treatment sequencing.

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