Bray F, Laversanne M, Sung H, Ferlay J, Siegel RL, Soerjomataram I, et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2024;74:229–63.
Miller KD, Nogueira L, Mariotto AB, Rowland JH, Yabroff KR, Alfano CM, et al. Cancer treatment and survivorship statistics, 2019. CA Cancer J Clin. 2019;69:363–85.
Gong Y, Liu YR, Ji P, Hu X, Shao ZM. Impact of molecular subtypes on metastatic breast cancer patients: a SEER population-based study. Sci Rep. 2017;7:45411.
Article CAS PubMed PubMed Central Google Scholar
Diamond JR, Finlayson CA, Borges VF. Hepatic complications of breast cancer. Lancet Oncol. 2009;10:615–21.
Ibragimova MK, Tsyganov MM, Kravtsova EA, Tsydenova IA, Litviakov NV. Organ-specificity of breast cancer metastasis. Int J Mol Sci. 2023;24:15625.
Article CAS PubMed PubMed Central Google Scholar
Luo X, Cheng C, Tan Z, Li N, Tang M, Yang L, et al. Emerging roles of lipid metabolism in cancer metastasis. Mol Cancer. 2017;16:76.
Article PubMed PubMed Central Google Scholar
Zipinotti Dos Santos D, de Souza JC, Pimenta TM, da Silva Martins B, Junior RSR, Butzene SMS, et al. The impact of lipid metabolism on breast cancer: a review about its role in tumorigenesis and immune escape. Cell Commun Signal. 2023;21:161.
Article CAS PubMed PubMed Central Google Scholar
Jiang W, Xing XL, Zhang C, Yi L, Xu W, Ou J, et al. MET and FASN as prognostic biomarkers of triple negative breast cancer: a systematic evidence landscape of clinical study. Front Oncol. 2021;11:604801.
Article CAS PubMed PubMed Central Google Scholar
Jung SH, Lee HC, Hwang HJ, Park HA, Moon YA, Kim BC, et al. Acyl-CoA thioesterase 7 is involved in cell cycle progression via regulation of PKCζ-p53-p21 signaling pathway. Cell Death Dis. 2017;8:e2793.
Article CAS PubMed PubMed Central Google Scholar
Sammarco A, Guerra G, Eyme KM, Kennewick K, Qiao Y, El Hokayem J, et al. Targeting SCD triggers lipotoxicity of cancer cells and enhances anti-tumor immunity in breast cancer brain metastasis mouse models. Commun Biol. 2025;8:562.
Article CAS PubMed PubMed Central Google Scholar
Ackermann T, Shokry E, Deshmukh R, Anand J, Galbraith LCA, Mitchell L, et al. Breast cancer secretes anti-ferroptotic MUFAs and depends on selenoprotein synthesis for metastasis. EMBO Mol Med. 2024;16:2749–74.
Article CAS PubMed PubMed Central Google Scholar
Pan J, Fan Z, Wang Z, Dai Q, Xiang Z, Yuan F, et al. CD36 mediates palmitate acid-induced metastasis of gastric cancer via AKT/GSK-3β/β-catenin pathway. J Exp Clin Cancer Res. 2019;38:52.
Article PubMed PubMed Central Google Scholar
Xiao J, Cao S, Wang J, Li P, Cheng Q, Zhou X, et al. Leptin-mediated suppression of lipoprotein lipase cleavage enhances lipid uptake and facilitates lymph node metastasis in gastric cancer. Cancer Commun. 2024;44:855–78.
Shen CJ, Chang KY, Lin BW, Lin WT, Su CM, Tsai JP, et al. Oleic acid-induced NOX4 is dependent on ANGPTL4 expression to promote human colorectal cancer metastasis. Theranostics. 2020;10:7083–99.
Article CAS PubMed PubMed Central Google Scholar
Xie X, Chen C, Feng S, Zuo S, Zhao X, Li H. Acyl-CoA thioesterase 7 is transcriptionally activated by krüppel-like factor 13 and promotes the progression of hepatocellular carcinoma. J Hepatocell Carcinoma. 2021;8:1623–41.
Article CAS PubMed PubMed Central Google Scholar
Wang T, Wang K, Zhu X, Chen N. ARNTL2 upregulation of ACOT7 promotes NSCLC cell proliferation through inhibition of apoptosis and ferroptosis. BMC Mol Cell Biol. 2023;24:14.
Article PubMed PubMed Central Google Scholar
Gan L, Meng J, Xu M, Liu M, Qi Y, Tan C, et al. Extracellular matrix protein 1 promotes cell metastasis and glucose metabolism by inducing integrin β4/FAK/SOX2/HIF-1α signaling pathway in gastric cancer. Oncogene. 2018;37:744–55.
Article CAS PubMed Google Scholar
Lal G, Hashimi S, Smith BJ, Lynch CF, Zhang L, Robinson RA, et al. Extracellular matrix 1 (ECM1) expression is a novel prognostic marker for poor long-term survival in breast cancer: a hospital-based cohort study in Iowa. Ann Surg Oncol. 2009;16:2280–7.
Yu Y, Lyu C, Li X, Yang L, Wang J, Li H, et al. Remodeling of tumor microenvironment by extracellular matrix protein 1a differentially regulates ovarian cancer metastasis. Cancer Lett. 2024;596:217022.
Article CAS PubMed Google Scholar
Yin H, Wang J, Li H, Yu Y, Wang X, Lu L, et al. Extracellular matrix protein-1 secretory isoform promotes ovarian cancer through increasing alternative mRNA splicing and stemness. Nat Commun. 2021;12:4230.
Article CAS PubMed PubMed Central Google Scholar
Wang J, Chen Y, Luo Z, Huang Q, Zhang Y, Ning H, et al. Citri Reticulatae Pericarpium-Reynoutria japonica Houtt. herb pair suppresses breast cancer liver metastasis by targeting ECM1-mediated cholesterol biosynthesis pathway. Phytomedicine. 2023;116:154896.
Article CAS PubMed Google Scholar
Yuan J, Liu Y, Zhang T, Zheng C, Ding X, Zhu C, et al. Traditional Chinese medicine for breast cancer treatment: a bibliometric and visualization analysis. Pharm Biol. 2024;62:499–512.
Article CAS PubMed PubMed Central Google Scholar
Kim BR, Ha J, Lee S, Park J, Cho S. Anti-cancer effects of ethanol extract of Reynoutria japonica Houtt. radix in human hepatocellular carcinoma cells via inhibition of MAPK and PI3K/Akt signaling pathways. J Ethnopharmacol. 2019;245:112179.
Article CAS PubMed Google Scholar
Song L, Xiong P, Zhang W, Hu H, Tang S, Jia B, et al. Mechanism of Citri Reticulatae Pericarpium as an anticancer agent from the perspective of flavonoids: a review. Molecules. 2022;27:5622.
Article CAS PubMed PubMed Central Google Scholar
Sp N, Kang DY, Joung YH, Park JH, Kim WS, Lee HK, et al. Nobiletin inhibits angiogenesis by regulating Src/FAK/STAT3-mediated signaling through PXN in ER⁺ breast cancer cells. Int J Mol Sci. 2017;18:935.
Article PubMed PubMed Central Google Scholar
Kim E, Kim YJ, Ji Z, Kang JM, Wirianto M, Paudel KR, et al. ROR activation by nobiletin enhances antitumor efficacy via suppression of IκB/NF-κB signaling in triple-negative breast cancer. Cell Death Dis. 2022;13:374.
Article CAS PubMed PubMed Central Google Scholar
Zhang T, Zhu X, Wu H, Jiang K, Zhao G, Shaukat A, et al. Targeting the ROS/PI3K/AKT/HIF-1α/HK2 axis of breast cancer cells: combined administration of polydatin and 2-Deoxy-d-glucose. J Cell Mol Med. 2019;23:3711–23.
Article CAS PubMed PubMed Central Google Scholar
Chen S, Tao J, Zhong F, Jiao Y, Xu J, Shen Q, et al. Polydatin down-regulates the phosphorylation level of Creb and induces apoptosis in human breast cancer cell. PLoS One. 2017;12:e0176501.
Article PubMed PubMed Central Google Scholar
Chou TC. Drug combination studies and their synergy quantification using the Chou-Talalay method. Cancer Res. 2010;70:440–6.
Article CAS PubMed Google Scholar
Guo Z, Bergeron KF, Mounier C. Oleate promotes triple-negative breast cancer cell migration by enhancing filopodia formation through a PLD/Cdc42-dependent pathway. Int J Mol Sci. 2024;25:34.
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