Autoimmune encephalitis

Dalmau, J. & Graus, F. Antibody-mediated encephalitis. N. Engl. J. Med. 378, 840–851 (2018).

Article  PubMed  Google Scholar 

Leypoldt, F. et al. Herpes simplex virus-1 encephalitis can trigger anti-NMDA receptor encephalitis: case report. Neurology 81, 1637–1639 (2013).

Article  PubMed  PubMed Central  Google Scholar 

Abboud, H. et al. Autoimmune encephalitis: proposed best practice recommendations for diagnosis and acute management. J. Neurol. Neurosurg. Psychiatry 92, 757–768 (2021).

Article  PubMed  Google Scholar 

Dalmau, J. et al. Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies. Lancet Neurol. 7, 1091–1098 (2008).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Titulaer, M. J. et al. Treatment and prognostic factors for long-term outcome in patients with anti-NMDA receptor encephalitis: an observational cohort study. Lancet Neurol. 12, 157–165 (2013). This study is the first large cohort description, depicting anti-NMDAR encephalitis, showing the effects of different treatments on long-term outcomes.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dalmau, J. et al. An update on anti-NMDA receptor encephalitis for neurologists and psychiatrists: mechanisms and models. Lancet Neurol. 18, 1045–1057 (2019).

Article  CAS  PubMed  Google Scholar 

Bastiaansen, A. E. M. et al. Anti-NMDAR encephalitis in the Netherlands, focusing on late-onset patients and antibody test accuracy. Neurol. Neuroimmunol. Neuroinflamm. 9, e1127 (2022).

Article  PubMed  Google Scholar 

van Sonderen, A. et al. The clinical spectrum of Caspr2 antibody-associated disease. Neurology 87, 521–528 (2016).

Article  PubMed  PubMed Central  Google Scholar 

Irani, S. R. et al. Faciobrachial dystonic seizures precede Lgi1 antibody limbic encephalitis. Ann. Neurol. 69, 892–900 (2011). This is the first description of faciobrachial dystonic seizures, the seizure type pathognomonic for anti-LGI1 encephalitis: recognition leads to earlier treatment.

Article  PubMed  Google Scholar 

Gaig, C. et al. Clinical manifestations of the anti-IgLON5 disease. Neurology 88, 1736–1743 (2017).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bastiaansen, A. E. M. et al. Autoimmune encephalitis resembling dementia syndromes. Neurol. Neuroimmunol. Neuroinflamm. https://doi.org/10.1212/NXI.0000000000001039 (2021).

Graus, F. et al. A clinical approach to diagnosis of autoimmune encephalitis. Lancet Neurol. 15, 391–404 (2016). This paper is the first international guideline for the diagnosis of autoimmune encephalitis.

Article  PubMed  PubMed Central  Google Scholar 

van Sonderen, A. et al. Anti-LGI1 encephalitis: clinical syndrome and long-term follow-up. Neurology 87, 1449–1456 (2016).

Article  PubMed  Google Scholar 

Thompson, J. et al. The importance of early immunotherapy in patients with faciobrachial dystonic seizures. Brain 141, 348–356 (2018).

Article  PubMed  Google Scholar 

Van Steenhoven, R. W. et al. Mimics of autoimmune encephalitis: validation of the 2016 clinical autoimmune encephalitis criteria. Neurol. Neuroimmunol. Neuroinflamm. 10, e200148 (2023). This paper describes the validation of criteria recommended by Graus, and a description of mimics and red flags to identify these mimics.

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Graus, F. et al. Updated diagnostic criteria for paraneoplastic neurologic syndromes. Neurol. Neuroimmunol. Neuroinflamm. https://doi.org/10.1212/NXI.0000000000001014 (2021). This paper describes the guideline to diagnose paraneoplastic neurological syndromes with the PNS Care score.

Dubey, D. et al. Randomized placebo-controlled trial of intravenous immunoglobulin in autoimmune LGI1/CASPR2 epilepsy. Ann. Neurol. 87, 313–323 (2020).

Article  CAS  PubMed  Google Scholar 

Banwell, B. et al. Diagnosis of myelin oligodendrocyte glycoprotein antibody-associated disease: International MOGAD panel proposed criteria. Lancet Neurol. 22, 268–282 (2023).

Article  CAS  PubMed  Google Scholar 

Wingerchuk, D. M. et al. International consensus diagnostic criteria for neuromyelitis optica spectrum disorders. Neurology 85, 177–189 (2015).

Article  PubMed  PubMed Central  Google Scholar 

Reindl, M., Jarius, S., Rostasy, K. & Berger, T. Myelin oligodendrocyte glycoprotein antibodies: how clinically useful are they? Curr. Opin. Neurol. 30, 295–301 (2017).

Article  CAS  PubMed  Google Scholar 

Muniz-Castrillo, S. et al. Novelties in autoimmune and paraneoplastic cerebellar ataxias: twenty years of progresses. Cerebellum 21, 573–591 (2022).

Article  PubMed  Google Scholar 

Armangue, T. et al. Frequency, symptoms, risk factors, and outcomes of autoimmune encephalitis after herpes simplex encephalitis: a prospective observational study and retrospective analysis. Lancet Neurol. 17, 760–772 (2018).

Article  PubMed  PubMed Central  Google Scholar 

Dubey, D. et al. Severe neurological toxicity of immune checkpoint inhibitors: growing spectrum. Ann. Neurol. 87, 659–669 (2020). This paper describes the link between immune checkpoint inhibitor neurotoxicity and autoimmune encephalitis.

Article  PubMed  Google Scholar 

Farina, A. et al. Neurological adverse events of immune checkpoint inhibitors and the development of paraneoplastic neurological syndromes. Lancet Neurol. 23, 81–94 (2024).

Article  CAS  PubMed  Google Scholar 

de Bruijn, M. et al. Pediatric autoimmune encephalitis: recognition and diagnosis. Neurol. Neuroimmunol. Neuroinflamm. 7, e682 (2020).

Article  PubMed  PubMed Central  Google Scholar 

Chen, L. W. et al. Antibody investigations in 2,750 children with suspected autoimmune encephalitis. Neurol. Neuroimmunol. Neuroinflamm. 11, e200182 (2024).

Article  PubMed  Google Scholar 

Hoftberger, R. et al. Encephalitis and AMPA receptor antibodies: novel findings in a case series of 22 patients. Neurology 84, 2403–2412 (2015).

Article  PubMed  PubMed Central  Google Scholar 

Kim, T. J. et al. Anti-LGI1 encephalitis is associated with unique HLA subtypes. Ann. Neurol. 81, 183–192 (2017).

Article  CAS  PubMed  Google Scholar 

van Sonderen, A. et al. Anti-LGI1 encephalitis is strongly associated with HLA-DR7 and HLA-DRB4. Ann. Neurol. 81, 193–198 (2017).

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Binks, S. et al. Distinct HLA associations of LGI1 and CASPR2-antibody diseases. Brain 141, 2263–2271 (2018).

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Armangue, T. et al. Neurologic complications in herpes simplex encephalitis: clinical, immunological and genetic studies. Brain 146, 4306–4319 (2023). This paper describes the link between HSV1 encephalitis and anti-NMDAR encephalitis.

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Mueller, S. H. et al. Genetic predisposition in anti-LGI1 and anti-NMDA receptor encephalitis. Ann. Neurol. 83, 863–869 (2018).

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Peris Sempere, V. et al. Human leukocyte antigen association study reveals DRB1*04:02 effects additional to DRB1*07:01 in anti-LGI1 encephalitis. Neurol. Neuroimmunol. Neuroinflamm. 9, e1140 (2022).

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Hor, J. Y. & Fujihara, K. Epidemiology of myelin oligodendrocyte glycoprotein antibody-associated disease: a review of prevalence and incidence worldwide. Front. Neurol. 14, 1260358 (2023).

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Tietz, A. K. et al. Genome-wide association study identifies 2 new loci associated with anti-NMDAR encephalitis. Neurol. Neuroimmunol. Neuroinflamm. 8, e1085 (2021).

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