Trabecular bone analysis: ultra-high-resolution CT goes far beyond high-resolution CT and gets closer to micro-CT (a study using Canon Medical CT devices)

Gillet R, Boubaker F, Hossu G, Thay A, Gillet P, Blum A, et al. Computed tomography bone imaging: pushing the boundaries in clinical practice. Semin Musculoskelet Radiol. 2023;27:397–410.

PubMed  Google Scholar 

Bolbos RI, Zuo J, Banerjee S, Link TM, Benjamin Ma C, Li X, et al. Relationship between trabecular bone structure and articular cartilage morphology and relaxation times in early OA of the knee joint using parallel MRI at 3T. Osteoarthritis Cartilage. 2008;16:1150–9.

CAS  PubMed  PubMed Central  Google Scholar 

Weinstein RS, Hutson MS. Decreased trabecular width and increased trabecular spacing contribute to bone loss with aging. Bone. 1987;8:137–42.

CAS  PubMed  Google Scholar 

Armas LAG, Akhter MP, Drincic A, Recker RR. Trabecular bone histomorphometry in humans with type 1 diabetes mellitus. Bone. 2012;50:91–6.

PubMed  Google Scholar 

Klintström B, Henriksson L, Moreno R, Malusek A, Smedby Ö, Woisetschläger M, et al. Photon-counting detector CT and energy-integrating detector CT for trabecular bone microstructure analysis of cubic specimens from human radius. Eur Radiol Exp. 2022;6:31.

PubMed  PubMed Central  Google Scholar 

Thomsen FSL, Horstmeier S, Niehoff JH, Peña JA, Borggrefe J. Effective spatial resolution of photon counting CT for imaging of trabecular structures is superior to conventional clinical CT and similar to high resolution peripheral CT. Invest Radiol. 2022;57:620–6.

CAS  PubMed  Google Scholar 

du Plessis A, Broeckhoven C, Guelpa A, le Roux SG. Laboratory x-ray micro-computed tomography: a user guideline for biological samples. Gigascience. 2017;6:1–11.

PubMed  PubMed Central  Google Scholar 

McCabe C, Sauer TJ, Zarei M, Segars WP, Samei E, Abadi E. A systematic assessment of photon-counting CT for bone mineral density and microarchitecture quantifications. Proc SPIE Int Soc Opt Eng. 2023;12463: 1246303.

PubMed  PubMed Central  Google Scholar 

Peña JA, Klein L, Maier J, Damm T, Schlemmer H-P, Engelke K, et al. Dose-efficient assessment of trabecular microstructure using ultra-high-resolution photon-counting CT. Z Med Phys. 2022. https://doi.org/10.1016/j.zemedi.2022.04.001.

Article  PubMed  PubMed Central  Google Scholar 

Gondim Teixeira PA, Villani N, Ait Idir M, Germain E, Lombard C, Gillet R, et al. Ultra-high resolution computed tomography of joints: practical recommendations for acquisition protocol optimization. Quant Imaging Med Surg. 2021;11:4287–98.

PubMed  PubMed Central  Google Scholar 

Inai R, Nakahara R, Morimitsu Y, Akagi N, Marukawa Y, Matsushita T, et al. Bone microarchitectural analysis using ultra-high-resolution CT in tiger vertebra and human tibia. Eur Radiol Exp. 2020;4:4.

PubMed  PubMed Central  Google Scholar 

Shi G, Subramanian S, Cao Q, Demehri S, Siewerdsen JH, Zbijewski W. Application of a novel ultra-high resolution multi-detector CT in quantitative imaging of trabecular microstructure. Proc SPIE Int Soc Opt Eng. 2020;11317: 113171E.

PubMed  PubMed Central  Google Scholar 

Boubaker F, Teixeira PAG, Hossu G, Douis N, Gillet P, Blum A, et al. In vivo depiction of cortical bone vascularization with ultra-high resolution-CT and deep learning algorithm reconstruction using osteoid osteoma as a model. Diagn Interv Imaging. 2024;105:26–32.

PubMed  Google Scholar 

Puel U, Eliezer M, Boubaker F, Villani N, Assabah B, Hossu G, et al. Effect of matrix size and acquisition mode on image quality and radiation dose of ultra-high-resolution CT of the temporal bone: an anatomical study. Can Assoc Radiol J. 2024. https://doi.org/10.1177/08465371241234795.

Article  PubMed  Google Scholar 

Beysang A, Villani N, Boubaker F, Puel U, Eliezer M, Hossu G, et al. Ultra-high-resolution CT of the temporal bone: comparison between deep learning reconstruction and hybrid and model-based iterative reconstruction. Diagn Interv Imaging. 2024;105:233–42.

PubMed  Google Scholar 

Domander R, Felder AA, Doube M. BoneJ2 - refactoring established research software. Wellcome Open Res. 2021. https://doi.org/10.12688/wellcomeopenres.16619.2.

Article  PubMed  PubMed Central  Google Scholar 

Benchoufi M, Matzner-Lober E, Molinari N, Jannot A-S, Soyer P. Interobserver agreement issues in radiology. Diagn Interv Imaging. 2020;101:639–41.

CAS  PubMed  Google Scholar 

Kawalilak CE, Kontulainen SA, Amini MA, Lanovaz JL, Olszynski WP, Johnston JD. In vivo precision of three HR-pQCT-derived finite element models of the distal radius and tibia in postmenopausal women. BMC Musculoskelet Disord. 2016;17:389.

CAS  PubMed  PubMed Central  Google Scholar 

Barat M, Jannot A-S, Dohan A, Soyer P. How to report and compare quantitative variables in a radiology article. Diagn Interv Imaging. 2022;103:571–3.

PubMed  Google Scholar 

Tsuji K, Kitamura M, Chiba K, Muta K, Yokota K, Okazaki N, et al. Comparison of bone microstructures via high-resolution peripheral quantitative computed tomography in patients with different stages of chronic kidney disease before and after starting hemodialysis. Ren Fail. 2022;44:381–91.

Mourad C, Gallego Manzano L, Viry A, Booij R, Oei EHG, Becce F, et al. Chances and challenges of photon-counting CT in musculoskeletal imaging. Skeletal Radiol. 2024;53:1889–902.

PubMed  PubMed Central  Google Scholar 

Greffier J, Viry A, Robert A, Khorsi M, Si-Mohamed S. Photon-counting CT systems: a technical review of current clinical possibilities. Diagn Interv Imaging. 2025;106(2):53–9.

PubMed  Google Scholar 

Boubaker F, Puel U, Eliezer M, Hossu G, Assabah B, Haioun K, et al. Radiation dose reduction and image quality improvement with ultra-high resolution temporal bone CT using deep learning-based reconstruction: an anatomical study. Diagn Interv Imaging. 2024;105:371–8.

PubMed  Google Scholar 

Bacchetta J, Boutroy S, Vilayphiou N, Juillard L, Guebre-Egziabher F, Rognant N, et al. Early impairment of trabecular microarchitecture assessed with HR-pQCT in patients with stage II-IV chronic kidney disease. J Bone Miner Res. 2010;25:849–57.

PubMed  Google Scholar 

Comments (0)

No login
gif