Combe B, Landewe R, Daien CI, Hua C, Aletaha D, Alvaro-Gracia JM, et al. 2016 update of the EULAR recommendations for the management of early arthritis. Ann Rheum Dis. 2017;76(6):948–59.

PubMed  Google Scholar 

Pincus T. Limitations of a quantitative swollen and tender joint count to assess and monitor patients with rheumatoid arthritis. Bull NYU Hosp Jt Dis. 2008;66(3):216–23.

PubMed  Google Scholar 

Pincus T, Segurado OG. Most visits of most patients with rheumatoid arthritis to most rheumatologists do not include a formal quantitative joint count. Ann Rheum Dis. 2006;65(6):820–2.

CAS  PubMed  Google Scholar 

Østergaard M, Pedersen SJ, Døhn UM. Imaging in rheumatoid arthritis–status and recent advances for magnetic resonance imaging, ultrasonography, computed tomography and conventional radiography. Best Pract Res Clin Rheumatol. 2008;22(6):1019–44.

PubMed  Google Scholar 

Bruyn GA, Iagnocco A, Naredo E, Balint PV, Gutierrez M, Hammer HB, et al. OMERACT definitions for ultrasonographic pathologies and elementary lesions of rheumatic disorders 15 years on. J Rheumatol. 2019;46(10):1388–93.

PubMed  Google Scholar 

Terslev L, Brahe CH, Hetland ML, Georgiadis S, Ellegaard K, Juul L, et al. Doppler ultrasound predicts successful discontinuation of biological DMARDs in rheumatoid arthritis patients in clinical remission. Rheumatology (Oxford). 2021;60(12):5549–59.

CAS  PubMed  Google Scholar 

Mandl P, Balint PV, Brault Y, Backhaus M, D’Agostino MA, Grassi W, et al. Metrologic properties of ultrasound versus clinical evaluation of synovitis in rheumatoid arthritis: results of a multicenter, randomized study. Arthritis Rheum. 2012;64(4):1272–82.

CAS  PubMed  Google Scholar 

Felson DT, Anderson JJ, Boers M, Bombardier C, Chernoff M, Fried B, et al. The American college of rheumatology preliminary core set of disease activity measures for rheumatoid arthritis clinical trials. Arthritis Rheum. 1993;36:729–40.

CAS  PubMed  Google Scholar 

Østergaard M, Wiell C. Ultrasonography in rheumatoid arthritis: a very promising method still needing more validation. Curr Opin Rheumatol. 2004;16(3):223–30.

PubMed  Google Scholar 

Carstensen SMD, Terslev L, Jensen MP, Østergaard M. Future use of musculoskeletal ultrasonography and magnetic resonance imaging in rheumatoid arthritis. Curr Opin Rheumatol. 2020;32(3):264–72.

PubMed  Google Scholar 

Saleem B, Brown AK, Keen H, Nizam S, Freeston J, Karim Z, et al. Disease remission state in patients treated with the combination of tumor necrosis factor blockade and methotrexate or with disease-modifying antirheumatic drugs: a clinical and imaging comparative study. Arthritis Rheum. 2009;60(7):1915–22.

CAS  PubMed  Google Scholar 

Spinella A, Sandri G, Carpenito G, Belletti L, Mascia MT. The discrepancy between clinical and ultrasonographic remission in rheumatoid arthritis is not related to therapy or autoantibody status. Rheumatol Int. 2012;32(12):3917–21.

CAS  PubMed  Google Scholar 

Terslev L, Brahe CH, Østergaard M, Fana V, Ammitzboll-Danielsen M, Moller T, et al. Using a DAS28-CRP-steered treat-to-target strategy does not eliminate subclinical inflammation as assessed by ultrasonography in rheumatoid arthritis patients in longstanding clinical remission. Arthritis Res Ther. 2021;23(1):48.

CAS  PubMed  PubMed Central  Google Scholar 

Filippou G, Sakellariou G, Scire CA, Carrara G, Rumi F, Bellis E, et al. The predictive role of ultrasound-detected tenosynovitis and joint synovitis for flare in patients with rheumatoid arthritis in stable remission. Results of an Italian multicentre study of the Italian Society for Rheumatology Group for Ultrasound: the STARTER study. Ann Rheum Dis. 2018;77(9):1283–9.

CAS  PubMed  Google Scholar 

Colebatch AN, Edwards CJ, Østergaard M, van der Heijde D, Balint PV, d’Agostino MA, et al. EULAR recommendations for the use of imaging of the joints in the clinical management of rheumatoid arthritis. Ann Rheum Dis. 2013;72(6):804–14.

PubMed  Google Scholar 

Dohn UM, Terslev L, Szkudlarek M, Hansen MS, Hetland ML, Hansen A, et al. Detection, scoring and volume assessment of bone erosions by ultrasonography in rheumatoid arthritis: comparison with CT. Ann Rheum Dis. 2013;72(4):530–4.

PubMed  Google Scholar 

Peterfy C, Østergaard M, Conaghan PG. MRI comes of age in RA clinical trials. Ann Rheum Dis. 2013;72(6):794–6.

PubMed  Google Scholar 

Alcalde M, D’Agostino MA, Bruyn GA, Moller I, Iagnocco A, Wakefield RJ, et al. A systematic literature review of US definitions, scoring systems and validity according to the OMERACT filter for tendon lesion in RA and other inflammatory joint diseases. Rheumatology (Oxford). 2012;51(7):1246–60.

PubMed  Google Scholar 

Freeston JE, Wakefield RJ, Conaghan PG, Hensor EM, Stewart SP, Emery P. A diagnostic algorithm for persistence of very early inflammatory arthritis: the utility of power Doppler ultrasound when added to conventional assessment tools. Ann Rheum Dis. 2010;69(2):417–9.

CAS  PubMed  Google Scholar 

Ammitzboll-Danielsen M, Fana V, Dohn UM, Moller T, Ng SN, Secher AE, et al. Ultrasound assessment of hands and feet for synovitis at time of first clinical visit markedly reduces time to diagnosis in routine care. Rheumatology (Oxford). 2022;61(5):2119–23.

PubMed  Google Scholar 

Horton SC, Tan AL, Wakefield RJ, Freeston JE, Buch MH, Emery P. Ultrasound-detectable grey scale synovitis predicts future fulfilment of the 2010 ACR/EULAR RA classification criteria in patients with new-onset undifferentiated arthritis. RMD Open. 2017;3(1).

PubMed  PubMed Central  Google Scholar 

Fiocco U, Ferro F, Vezzu M, Cozzi L, Checchetto C, Sfriso P, et al. Rheumatoid and psoriatic knee synovitis: clinical, grey scale, and power Doppler ultrasound assessment of the response to etanercept. Ann Rheum Dis. 2005;64(6):899–905.

CAS  PubMed  Google Scholar 

Naredo E, Rodriguez M, Campos C, Rodriguez-Heredia JM, Medina JA, Giner E, et al. Validity, reproducibility, and responsiveness of a twelve-joint simplified power doppler ultrasonographic assessment of joint inflammation in rheumatoid arthritis. Arthritis Rheum. 2008;59(4):515–22.

PubMed  Google Scholar 

Filippucci E, Iagnocco A, Salaffi F, Cerioni A, Valesini G, Grassi W. Power doppler sonography monitoring of synovial perfusion at the wrist joints in patients with rheumatoid arthritis treated with adalimumab. Ann Rheum Dis. 2006;65(11):1433–7.

CAS  PubMed  PubMed Central  Google Scholar 

Ammitzbøll-Danielsen M, Østergaard M, Naredo E, Terslev L. Validity and sensitivity to change of the semi-quantitative OMERACT ultrasound scoring system for tenosynovitis in patients with rheumatoid arthritis. Rheumatology (Oxford). 2016;55(12):2156–66.

PubMed  Google Scholar 

Ammitzbøll-Danielsen M, Østergaard M, Fana V, Glinatsi D, Døhn UM, Ørnbjerg LM, et al. Intramuscular versus ultrasound-guided intratenosynovial glucocorticoid injection for tenosynovitis in patients with rheumatoid arthritis: a randomised, double-blind, controlled study. Ann Rheum Dis. 2017;76(4):666–72.

PubMed  Google Scholar 

D’Agostino MA, Beaton DE, Maxwell LJ, Cembalo SM, Hoens AM, Hofstetter C, et al. Improving domain definition and outcome instrument selection: lessons learned for OMERACT from imaging. Semin Arthritis Rheum. 2021;51(5):1125–33.

PubMed  Google Scholar 

Beaton DE, Maxwell LJ, Shea BJ, Wells GA, Boers M, Grosskleg S, et al. Instrument selection using the OMERACT filter 2.1: the OMERACT methodology. J Rheumatol. 2019;46(8):1028–35.

PubMed  Google Scholar 

Terslev L, Naredo E, Keen HI, Bruyn GAW, Iagnocco A, Wakefield RJ, et al. The OMERACT stepwise approach to select and develop imaging outcome measurement instruments: the musculoskeletal ultrasound example. J Rheumatol. 2019;46(10):1394–400.

PubMed  Google Scholar 

D’Agostino MA, Terslev L, Aegerter P, Backhaus M, Balint P, Bruyn GA, et al. Scoring ultrasound synovitis in rheumatoid arthritis: a EULAR-OMERACT ultrasound taskforce-part 1: definition and development of a standardised, consensus-based scoring system. RMD Open. 2017;3(1).

PubMed  PubMed Central  Google Scholar 

Terslev L, Naredo E, Aegerter P, Wakefield RJ, Backhaus M, Balint P, et al. Scoring ultrasound synovitis in rheumatoid arthritis: a EULAR-OMERACT ultrasound taskforce-Part 2: reliability and application to multiple joints of a standardised consensus-based scoring system. RMD Open. 2017;3(1).

PubMed  PubMed Central  Google Scholar 

Naredo E, d’Agostino MA, Wakefield RJ, Moller I, Balint PV, Filippucci E, et al. Reliability of a consensus-based ultrasound score for tenosynovitis in rheumatoid arthritis. Ann Rheum Dis. 2013;72(8):1328–34.

PubMed  Google Scholar 

Terslev L, Østergaard M, Georgiadis S, Brahe CH, Ellegaard K, Døhn UM, et al. Flare during tapering of biological DMARDs in patients with rheumatoid arthritis in routine care: characteristics and predictors. RMD Open. 2022; 8(2).

D’Agostino MA, Wakefield RJ, Berner-Hammer H, Vittecoq O, Filippou G, Balint P, et al. Value of ultrasonography as a marker of early response to abatacept in patients with rheumatoid arthritis and an inadequate response to methotrexate: results from the APPRAISE study. Ann Rheum Dis. 2016;75(10):1763–9.

CAS  PubMed  Google Scholar 

Just SA, Nielsen C, Werlinrud JC, Larsen PV, Klinkby CS, Schroder HD, et al. Six-month prospective trial in early and long-standing rheumatoid arthritis: evaluating disease activity in the wrist through sequential synovial histopathological analysis, RAMRIS magnetic resonance score and EULAR-OMERACT ultrasound score. RMD Open. 2019;5(2).

PubMed  PubMed Central  Google Scholar 

Boers M, Brooks P, Strand CV, Tugwell P. The OMERACT filter for outcome measures in rheumatology. J Rheumatol. 1998;25(2):198–9.

CAS  PubMed  Google Scholar 

Østergaard M, Stoltenberg M, Løvgreen-Nielsen P, Volck B, Jensen CH, Lorenzen I. Magnetic resonance imaging-determined synovial membrane and joint effusion volumes in rheumatoid arthritis and osteoarthritis: comparison with the macroscopic and microscopic appearance of the synovium. Arthritis Rheum. 1997;40(10):1856–67.

PubMed  Google Scholar 

Østergaard M, Hansen M, Stoltenberg M, Gideon P, Klarlund M, Jensen KE, et al. Magnetic resonance imaging-determined synovial membrane volume as a marker of disease activity and a predictor of progressive joint destruction in the wrists of patients with rheumatoid arthritis. Arthritis Rheum. 1999;42(5):918–29.

PubMed