Admission hematocrit and fluctuating blood urea nitrogen levels predict the efficacy of blood purification treatment in severe acute pancreatitis patients

Wang HL, Yu KJ. Sequential blood purification therapy for critical patients with hyperlipidemic severe acute pancreatitis. World J Gastroenterol. 2015;21(20):6304–9.

Article  PubMed  PubMed Central  Google Scholar 

Li J, Gao J, Huang M, Fu X, Fu B. Risk factors for death in patients with severe acute pancreatitis in Guizhou Province. China Gastroenterol Res Pract. 2024;2024:8236616.

Article  PubMed  Google Scholar 

Zerem E. Treatment of severe acute pancreatitis and its complications. World J Gastroenterol. 2014;20(38):13879–92.

Article  PubMed  PubMed Central  Google Scholar 

Hidalgo NJ, Pando E, Mata R, Fernandes N, Villasante S, Barros M, et al. Impact of comorbidities on hospital mortality in patients with acute pancreatitis: a population-based study of 110,021 patients. BMC Gastroenterol. 2023;23(1):81.

Article  PubMed  PubMed Central  Google Scholar 

Zhu AJ, Shi JS, Sun XJ. Organ failure associated with severe acute pancreatitis. World J Gastroenterol. 2003;9(11):2570–3.

Article  PubMed  PubMed Central  Google Scholar 

Li S, Yin D, Guo XC. Influence of standardized nursing intervention combined with mindfulness stress reduction training on the curative effect in patients with acute pancreatitis. World J Clin Cases. 2023;11(35):8276–83.

Article  PubMed  PubMed Central  Google Scholar 

Walkowska J, Zielinska N, Tubbs RS, Podgórski M, Dłubek-Ruxer J, Olewnik Ł. Diagnosis and treatment of acute pancreatitis. Diagnostics (Basel). 2022;12(8):1974.

Article  CAS  PubMed  Google Scholar 

Hu Y, Xiong W, Li C, Cui Y. Continuous blood purification for severe acute pancreatitis: a systematic review and meta-analysis. Medicine (Baltimore). 2019;98(12): e14873.

Article  PubMed  Google Scholar 

Kellum JA, Ronco C. The 17th acute disease quality initiative international consensus conference: introducing precision renal replacement therapy. Blood Purif. 2016;42(3):221–3.

Article  PubMed  Google Scholar 

Kuykendall AT, Komrokji R. What’s in a number? Examining the prognostic and predictive importance of platelet count in patients with essential thrombocythemia. J Natl Compr Canc Netw. 2020;18(9):1279–84.

Article  CAS  PubMed  Google Scholar 

Valverde-López F, Matas-Cobos AM, Alegría-Motte C, Jiménez-Rosales R, Úbeda-Muñoz M, Redondo-Cerezo E. BISAP, RANSON, lactate, and others biomarkers in prediction of severe acute pancreatitis in a European cohort. J Gastroenterol Hepatol. 2017;32(9):1649–56.

Article  PubMed  Google Scholar 

Khanna AK, Meher S, Prakash S, Tiwary SK, Singh U, Srivastava A, et al. Comparison of ranson, glasgow, MOSS, SIRS, BISAP, APACHE-II, CTSI scores, IL-6, CRP, and procalcitonin in predicting severity, organ failure, pancreatic necrosis, and mortality in acute pancreatitis. HPB Surg. 2013;2013: 367581.

Article  PubMed  PubMed Central  Google Scholar 

He WH, Zhu Y, Zhu Y, Jin Q, Xu HR, Xion ZJ, et al. Comparison of multifactor scoring systems and single serum markers for the early prediction of the severity of acute pancreatitis. J Gastroenterol Hepatol. 2017;32(11):1895–901.

Article  CAS  PubMed  Google Scholar 

Vitale DS, Hornung L, Lin TK, Nathan JD, Prasad S, Thompson T, et al. Blood urea nitrogen elevation is a marker for pediatric severe acute pancreatitis. Pancreas. 2019;48(3):363–6.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lin S, Hong W, Basharat Z, Wang Q, Pan J, Zhou M. Blood urea nitrogen as a predictor of severe acute pancreatitis based on the revised Atlanta criteria: timing of measurement and cutoff points. Can J Gastroenterol Hepatol. 2017;2017:9592831.

Article  PubMed  PubMed Central  Google Scholar 

Pando E, Alberti P, Mata R, Gomez MJ, Vidal L, Cirera A, et al. Early changes in blood urea nitrogen (BUN) can predict mortality in acute pancreatitis: comparative study between BISAP score, APACHE-II, and other laboratory markers-a prospective observational study. Can J Gastroenterol Hepatol. 2021;2021:6643595.

Article  PubMed  PubMed Central  Google Scholar 

Dai M, Fan Y, Pan P, Tan Y. Blood urea nitrogen as a prognostic marker in severe acute pancreatitis. Dis Markers. 2022;2022:7785497.

Article  PubMed  PubMed Central  Google Scholar 

Saif MW, Allegra CJ. Hematological complications of acute pancreatitis: a review. Resid Staff Physician. 2001;47(10):29–35.

PubMed  PubMed Central  Google Scholar 

Metri A, Bush N, Singh VK. Predicting the severity of acute pancreatitis: current approaches and future directions. Surg Open Sci. 2024;19:109–17.

Article  PubMed  PubMed Central  Google Scholar 

Brown A, Baillargeon JD, Hughes MD, Banks PA. Can fluid resuscitation prevent pancreatic necrosis in severe acute pancreatitis? Pancreatology. 2002;2(2):104–7.

Article  CAS  PubMed  Google Scholar 

Koutroumpakis E, Wu BU, Bakker OJ, Dudekula A, Singh VK, Besselink MG, et al. Admission hematocrit and rise in blood urea nitrogen at 24 h outperform other laboratory markers in predicting persistent organ failure and pancreatic necrosis in acute pancreatitis: a post hoc analysis of three large prospective databases. Am J Gastroenterol. 2016;111(8):1216.

Article  PubMed  Google Scholar 

Luo M, Chen Y, Cheng Y, Li N, Qing H. Association between hematocrit and the 30-day mortality of patients with sepsis: a retrospective analysis based on the large-scale clinical database MIMIC-IV. PLoS ONE. 2022;17(3): e0265758.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Khoury J, Bahouth F, Stabholz Y, Elias A, Mashiach T, Aronson D. Blood urea nitrogen variation upon admission and at discharge in patients with heart failure. ESC Heart Fail. 2019;6(4):809–16.

Article  PubMed  PubMed Central  Google Scholar 

Dawson A, Karunakaran M, Sharma ZD, Ullah S, Barreto SG. Fluid resuscitation in the early management of acute pancreatitis - evidence from a systematic review and meta-analysis. HPB (Oxford). 2023;25(12):1451–65.

Article  PubMed  Google Scholar 

Zhang XC, Lu ZH, Yu WL, Hu QY, Fu L, Chen H, et al. Clinical characteristics and early prognostic factors of severe acute pancreatitis. Hepat Mon. 2021;21(5): e114638.

Article  CAS  Google Scholar 

He SS, Li D, He QY, Chen XP, Lin YX, Yu YW, et al. Establishment of early multi-indicator prediction models of moderately severe acute pancreatitis and severe acute pancreatitis. Gastroenterol Res Pract. 2022;2022:5142473.

Article  PubMed  PubMed Central  Google Scholar 

Ak C, Kahraman R, Sayar S, Kilic ET, Adali G, Ozdil K. Prediction of prognosis acute pancreatitis with inflammatory markers and patient characteristics compared to the scoring system: real-life data. Sisli Etfal Hastan Tip Bul. 2023;57(2):182–8.

Article  PubMed  PubMed Central  Google Scholar 

Huang H, Mo J, Jiang G, Lu Z. Evaluating the therapeutic efficiency and efficacy of blood purification for treating severe acute pancreatitis: a single-center data based on propensity score matching. Int J Gen Med. 2024;17:3765–77.

Article  PubMed  PubMed Central  Google Scholar 

Banks PA, Bollen TL, Dervenis C, Gooszen HG, Johnson CD, Sarr MG, et al. Classification of acute pancreatitis–2012: revision of the Atlanta classification and definitions by international consensus. Gut. 2013;62(1):102–11.

Article  PubMed  Google Scholar 

Banks PA, Bollen TL, Dervenis C, Gooszen HG, Johnson CD, Sarr MG, et al. Acute renal failure in severe pancreatitis: a population-based study. Ups J Med Sci. 2011;116(2):155–9.

Article  Google Scholar 

Li M, Han S, Liang F, Hu C, Zhang B, Hou Q, et al. Machine learning for predicting risk and prognosis of acute kidney disease in critically Ill elderly patients during hospitalization: internet-based and interpretable model study. J Med Internet Res. 2024;26: e51354.

Article  PubMed  PubMed Central  Google Scholar 

Huang H, Huang Z, Chen M, Okamoto K. Evaluatio

Comments (0)

No login
gif