Pavel M, Öberg K, Falconi M, Krenning EP, Sundin A, Perren A, et al. Gastroenteropancreatic neuroendocrine neoplasms: ESMO clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2020;31:844–60. https://doi.org/10.1016/j.annonc.2020.03.304.
Article CAS PubMed Google Scholar
Baudin E, Caplin M, Garcia-Carbonero R, Fazio N, Ferolla P, Filosso PL, et al. Lung and thymic carcinoids: ESMO clinical practice guidelines for diagnosis, treatment and follow-up(☆). Ann Oncol. 2021;32:439–51. https://doi.org/10.1016/j.annonc.2021.01.003.
Article CAS PubMed Google Scholar
Sorbye H, Grande E, Pavel M, Tesselaar M, Fazio N, Reed NS, et al. European neuroendocrine tumor society (ENETS) 2023 guidance paper for digestive neuroendocrine carcinoma. J Neuroendocrinol. 2023;35:e13249. https://doi.org/10.1111/jne.13249.
Article CAS PubMed Google Scholar
Kos-Kudła B, Castaño JP, Denecke T, Grande E, Kjaer A, Koumarianou A, et al. European neuroendocrine tumour society (ENETS) 2023 guidance paper for nonfunctioning pancreatic neuroendocrine tumours. J Neuroendocrinol. 2023;35:e13343. https://doi.org/10.1111/jne.13343.
Article CAS PubMed Google Scholar
Dasari A, Shen C, Halperin D, Zhao B, Zhou S, Xu Y, et al. Trends in the incidence, prevalence, and survival outcomes in patients with neuroendocrine tumors in the united States. JAMA Oncol. 2017;3:1335–42. https://doi.org/10.1001/jamaoncol.2017.0589.
Article PubMed PubMed Central Google Scholar
Rindi G, Klimstra DS, Abedi-Ardekani B, Asa SL, Bosman FT, Brambilla E, et al. A common classification framework for neuroendocrine neoplasms: an international agency for research on Cancer (IARC) and world health organization (WHO) expert consensus proposal. Mod Pathol. 2018;31:1770–86. https://doi.org/10.1038/s41379-018-0110-y.
Article PubMed PubMed Central Google Scholar
Rindi G, Mete O, Uccella S, Basturk O, La Rosa S, Brosens LAA, et al. Overview of the 2022 WHO classification of neuroendocrine neoplasms. Endocr Pathol. 2022;33:115–54. https://doi.org/10.1007/s12022-022-09708-2.
Article CAS PubMed Google Scholar
Nuñez-Valdovinos B, Carmona-Bayonas A, Jimenez-Fonseca P, Capdevila J, Castaño-Pascual Á, Benavent M, et al. Neuroendocrine Tumor Heterogeneity Adds Uncertainty to the World Health Organization 2010 Classification: Real-World Data from the Spanish Tumor Registry (R-GETNE). Oncologist. 2018;23:422−32. https://doi.org/10.1634/theoncologist.2017-0364
Tang LH, Basturk O, Sue JJ, Klimstra DS. A practical approach to the classification of WHO grade 3 (G3) Well-differentiated neuroendocrine tumor (WD-NET) and poorly differentiated neuroendocrine carcinoma (PD-NEC) of the pancreas. Am J Surg Pathol. 2016;40:1192–202. https://doi.org/10.1097/pas.0000000000000662.
Article PubMed PubMed Central Google Scholar
Günther T, Tulipano G, Dournaud P, Bousquet C, Csaba Z, Kreienkamp HJ, et al. International union of basic and clinical pharmacology. CV. Somatostatin receptors: structure, function, ligands, and new nomenclature. Pharmacol Rev. 2018;70:763–835. https://doi.org/10.1124/pr.117.015388.
Article CAS PubMed PubMed Central Google Scholar
Dhani N, Tu D, Sargent DJ, Seymour L, Moore MJ. Alternate endpoints for screening phase II studies. Clin Cancer Res. 2009;15:1873–82. https://doi.org/10.1158/1078-0432.Ccr-08-2034.
Article CAS PubMed Google Scholar
Imaoka H, Sasaki M, Takahashi H, Hashimoto Y, Ohno I, Mitsunaga S, et al. Progression-free survival as a surrogate endpoint in advanced neuroendocrine neoplasms. Endocr Relat Cancer. 2017;24:475–83. https://doi.org/10.1530/erc-17-0197.
Article CAS PubMed Google Scholar
Kulke MH, Siu LL, Tepper JE, Fisher G, Jaffe D, Haller DG, et al. Future directions in the treatment of neuroendocrine tumors: consensus report of the National Cancer Institute neuroendocrine tumor clinical trials planning meeting. J Clin Oncol. 2011;29:934–43. https://doi.org/10.1200/jco.2010.33.2056.
Article CAS PubMed PubMed Central Google Scholar
Caplin ME, Pavel M, Ćwikła JB, Phan AT, Raderer M, Sedláčková E, et al. Lanreotide in metastatic enteropancreatic neuroendocrine tumors. N Engl J Med. 2014;371:224–33. https://doi.org/10.1056/NEJMoa1316158.
Article CAS PubMed Google Scholar
Rinke A, Müller H-H, Schade-Brittinger C, Klose K-J, Barth P, Wied M, et al. Placebo-Controlled, Double-Blind, prospective, randomized study on the effect of octreotide LAR in the control of tumor growth in patients with metastatic neuroendocrine midgut tumors: A report from the PROMID study group. J Clin Oncol. 2009;27:4656–63. https://doi.org/10.1200/jco.2009.22.8510.
Article CAS PubMed Google Scholar
Yao JC, Shah MH, Ito T, Bohas CL, Wolin EM, Van Cutsem E, et al. Everolimus for advanced pancreatic neuroendocrine tumors. N Engl J Med. 2011;364:514–23. https://doi.org/10.1056/NEJMoa1009290.
Article CAS PubMed PubMed Central Google Scholar
Yao JC, Fazio N, Singh S, Buzzoni R, Carnaghi C, Wolin E, et al. Everolimus for the treatment of advanced, non-functional neuroendocrine tumours of the lung or Gastrointestinal tract (RADIANT-4): a randomised, placebo-controlled, phase 3 study. Lancet. 2016;387:968–77. https://doi.org/10.1016/S0140-6736(15)00817-X.
Article CAS PubMed Google Scholar
Raymond E, Dahan L, Raoul JL, Bang YJ, Borbath I, Lombard-Bohas C, et al. Sunitinib malate for the treatment of pancreatic neuroendocrine tumors. N Engl J Med. 2011;364:501–13. https://doi.org/10.1056/NEJMoa1003825.
Article CAS PubMed Google Scholar
Strosberg J, El-Haddad G, Wolin E, Hendifar A, Yao J, Chasen B, et al. Phase 3 trial of 177Lu-Dotatate for midgut neuroendocrine tumors. N Engl J Med. 2017;376:125–35. https://doi.org/10.1056/NEJMoa1607427.
Article CAS PubMed PubMed Central Google Scholar
Singh S, Halperin D, Myrehaug S, Herrmann K, Pavel M, Kunz PL, et al. [(177)Lu]Lu-DOTA-TATE plus long-acting octreotide versus high–dose long-acting octreotide for the treatment of newly diagnosed, advanced grade 2–3, well-differentiated, gastroenteropancreatic neuroendocrine tumours (NETTER-2): an open-label, randomised, phase 3 study. Lancet. 2024. https://doi.org/10.1016/s0140-6736(24)00701-3.
Article PubMed PubMed Central Google Scholar
Von Hoff DD. There are no bad anticancer agents, only bad clinical trial designs–twenty-first Richard and Hinda rosenthal foundation award lecture. Clin Cancer Res. 1998;4:1079–86.
Von Hoff DD, Stephenson JJ Jr., Rosen P, Loesch DM, Borad MJ, Anthony S, et al. Pilot study using molecular profiling of patients’ tumors to find potential targets and select treatments for their refractory cancers. J Clin Oncol. 2010;28:4877–83. https://doi.org/10.1200/jco.2009.26.5983.
Rodon J, Soria JC, Berger R, Miller WH, Rubin E, Kugel A, et al. Genomic and transcriptomic profiling expands precision cancer medicine: the WINTHER trial. Nat Med. 2019;25:751–8. https://doi.org/10.1038/s41591-019-0424-4.
Article CAS PubMed PubMed Central Google Scholar
Verlingue L, Malka D, Allorant A, Massard C, Ferté C, Lacroix L, et al. Precision medicine for patients with advanced biliary tract cancers: an effective strategy within the prospective MOSCATO-01 trial. Eur J Cancer. 2017;87:122–30. https://doi.org/10.1016/j.ejca.2017.10.013.
Prager GW, Unseld M, Waneck F, Mader R, Wrba F, Raderer M, et al. Results of the extended analysis for cancer treatment (EXACT) trial: a prospective translational study evaluating individualized treatment regimens in oncology. Oncotarget. 2019;10:942–52. https://doi.org/10.18632/oncotarget.26604.
Article PubMed PubMed Central Google Scholar
van de Kruis N, van der Ploeg P, Wilting JHC, Caroline Vos M, Thijs AMJ, de Hullu J, et al. The progression-free survival ratio as outcome measure in recurrent ovarian carcinoma patients: current and future perspectives. Gynecol Oncol Rep. 2022;42:101035. https://doi.org/10.1016/j.gore.2022.101035.
Article PubMed PubMed Central Google Scholar
du Rusquec P, Guimbaud R, Le Malicot K, Gornet JM, Nguyen S, Lecomte T, et al. Evaluation of the relevance of the growth modulation index (GMI) from the FFCD 0307 randomized phase III trial comparing the sequence of two chemotherapeutic regimens. ESMO Open. 2023;8:101616. https://doi.org/10.1016/j.esmoop.2023.101616.
Article PubMed PubMed Central Google Scholar
Doleschal B, Taghizadeh H, Webersinke G, Piringer G, Schreil G, Decker J, et al. Real world evide
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