Guan WJ, Ni ZY, Hu Y, Liang WH, Ou CQ, He JX, et al. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med. 2020;382(18):1708–20.
Article CAS PubMed Google Scholar
Global burden of. 288 Causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the global burden of disease study 2021. Lancet. 2024;403(10440):2100–32.
Wool GD, Miller JL. The impact of COVID-19 disease on platelets and coagulation. Pathobiology. 2021;88(1):15–27.
Article CAS PubMed Google Scholar
Sarkar M, Madabhavi IV, Quy PN, Govindagoudar MB. COVID-19 and coagulopathy. Clin Respir J. 2021;15(12):1259–74.
Article CAS PubMed Google Scholar
Dybowska M, Wyrostkiewicz D, Opoka L, Lewandowska K, Sobiecka M, Tomkowski W et al. Venous thromboembolic disease in COVID-19, pathophysiology, therapy and prophylaxis. Int J Mol Sci. 2022;23(18).
Trimaille A, Bonnet G. [COVID-19 and venous thromboembolism]. Ann Cardiol Angeiol (Paris). 2020;69(6):370–5.
Article CAS PubMed Google Scholar
Bertoletti L, Couturaud F, Montani D, Parent F, Sanchez O. Venous thromboembolism and COVID-19. Respir Med Res. 2020;78:100759.
CAS PubMed PubMed Central Google Scholar
Zuin M, Rigatelli G, Bilato C, Quadretti L, Roncon L, Zuliani G. COVID-19 patients with acute pulmonary embolism have a higher mortality risk: systematic review and meta-analysis based on Italian cohorts. J Cardiovasc Med (Hagerstown). 2022;23(12):773–8.
Deitelzweig S, Luo X, Nguyen JL, Malhotra D, Emir B, Russ C, et al. Thrombotic and bleeding events, mortality, and anticoagulant use among 546,656 hospitalized patients with COVID-19 in the united States: a retrospective cohort study. J Thromb Thrombolysis. 2022;53(4):766–76.
Article CAS PubMed PubMed Central Google Scholar
Farkouh ME, Stone GW, Lala A, Bagiella E, Moreno PR, Nadkarni GN, et al. Anticoagulation in patients with COVID-19: JACC review topic of the week. J Am Coll Cardiol. 2022;79(9):917–28.
Article CAS PubMed PubMed Central Google Scholar
Fanaroff AC, Lopes RD. COVID-19 thrombotic complications and therapeutic strategies. Annu Rev Med. 2023;74:15–30.
Article CAS PubMed Google Scholar
Schulman S, Sholzberg M, Spyropoulos AC, Zarychanski R, Resnick HE, Bradbury CA, et al. ISTH guidelines for antithrombotic treatment in COVID-19. J Thromb Haemost. 2022;20(10):2214–25.
Article CAS PubMed PubMed Central Google Scholar
Siegal DM, Tseng EK, Schünemann HJ, Angchaisuksiri P, Cuker A, Dane K, et al. American society of hematology living guidelines on use of anticoagulation for thromboprophylaxis for patients with COVID-19: executive summary. Blood Adv. 2025;9(6):1247–60.
Article CAS PubMed Google Scholar
Bikdeli B, Talasaz AH, Rashidi F, Bakhshandeh H, Rafiee F, Rezaeifar P, et al. Intermediate-Dose versus Standard-Dose prophylactic anticoagulation in patients with COVID-19 admitted to the intensive care unit: 90-Day results from the INSPIRATION randomized trial. Thromb Haemost. 2022;122(1):131–41.
Zhai Z, Kan Q, Li W, Qin X, Qu J, Shi Y, et al. VTE risk profiles and prophylaxis in medical and surgical inpatients: the identification of Chinese hospitalized patients’ risk profile for venous thromboembolism (DissolVE-2)-A Cross-sectional study. Chest. 2019;155(1):114–22.
Moores LK, Tritschler T, Brosnahan S, Carrier M, Collen JF, Doerschug K, et al. Thromboprophylaxis in patients with COVID-19: A brief update to the CHEST guideline and expert panel report. Chest. 2022;162(1):213–25.
Article CAS PubMed Google Scholar
Kyriakoulis KG, Dimakakos E, Kyriakoulis IG, Catalano M, Spyropoulos AC, Schulman S et al. Practical recommendations for optimal thromboprophylaxis in patients with COVID-19: A consensus statement based on available clinical trials. J Clin Med. 2022;11(20).
Diagnosis. Treatment protocol for COVID-19 patients (Tentative 10th Version). Health Care Sci. 2023;2(1):10–24.
Schulman S, Kearon C. Definition of major bleeding in clinical investigations of antihemostatic medicinal products in non-surgical patients. J Thromb Haemost. 2005;3(4):692–4.
Article CAS PubMed Google Scholar
Kaatz S, Ahmad D, Spyropoulos AC, Schulman S. Definition of clinically relevant non-major bleeding in studies of anticoagulants in atrial fibrillation and venous thromboembolic disease in non-surgical patients: communication from the SSC of the ISTH. J Thromb Haemost. 2015;13(11):2119–26.
Article CAS PubMed Google Scholar
Kim HK, Tantry US, Smith SC Jr., Jeong MH, Park SJ, Kim MH, et al. The East Asian paradox: an updated position statement on the challenges to the current antithrombotic strategy in patients with cardiovascular disease. Thromb Haemost. 2021;121(4):422–32.
Patel AP, Wang M, Pirruccello JP, Ellinor PT, Ng K, Kathiresan S, et al. Lp(a) (Lipoprotein[a]) concentrations and incident atherosclerotic cardiovascular disease: new insights from a large National biobank. Arterioscler Thromb Vasc Biol. 2021;41(1):465–74.
Article CAS PubMed Google Scholar
Jeong YH, Kevin B, Ahn JH, Chaudhary R, Kang MG, Park HW, et al. Viscoelastic properties of clot formation and their clinical impact in East Asian versus Caucasian patients with stable coronary artery disease: a COMPARE-RACE analysis. J Thromb Thrombolysis. 2021;51(2):454–65.
Article CAS PubMed Google Scholar
Albert MA, Glynn RJ, Buring J, Ridker PM. C-reactive protein levels among women of various ethnic groups living in the united States (from the women’s health Study). Am J Cardiol. 2004;93(10):1238–42.
Article CAS PubMed Google Scholar
Hayashi H, Izumiya Y, Fukuda D, Wakita F, Mizobata Y, Fujii H, et al. Real-World management of Pharmacological thromboprophylactic strategies for COVID-19 patients in Japan: from the CLOT-COVID study. JACC Asia. 2022;2(7):897–907.
Article PubMed PubMed Central Google Scholar
Voigtlaender M, Edler C, Gerling M, Schädler J, Ondruschka B, Schröder AS, et al. Thromboembolic events in deceased patients with proven SARS-CoV-2 infection: frequency, characteristics and risk factors. Thromb Res. 2022;218:171–6.
Article CAS PubMed PubMed Central Google Scholar
Lobbes H, Mainbourg S, Mai V, Douplat M, Provencher S, Lega JC. Risk factors for venous thromboembolism in severe COVID-19: A Study-Level Meta-Analysis of 21 studies. Int J Environ Res Public Health. 2021;18(24).
Decousus H, Tapson VF, Bergmann JF, Chong BH, Froehlich JB, Kakkar AK, et al. Factors at admission associated with bleeding risk in medical patients: findings from the IMPROVE investigators. Chest. 2011;139(1):69–79.
Sadeghipour P, Talasaz AH, Rashidi F, Sharif-Kashani B, Beigmohammadi MT, Farrokhpour M, et al. Effect of Intermediate-Dose vs Standard-Dose prophylactic anticoagulation on thrombotic events, extracorporeal membrane oxygenation treatment, or mortality among patients with COVID-19 admitted to the intensive care unit: the INSPIRATION randomized clinical trial. JAMA. 2021;325(16):1620–30.
Article CAS PubMed Google Scholar
Goligher EC, Bradbury CA, McVerry BJ, Lawler PR, Berger JS, Gong MN, et al. Therapeutic anticoagulation with heparin in critically ill patients with Covid-19. N Engl J Med. 2021;385(9):777–89.
Bohula EA, Berg DD, Lopes MS, Connors JM, Babar I, Barnett CF, et al. Anticoagulation and antiplatelet therapy for prevention of venous and arterial thrombotic events in critically ill patients with COVID-19: COVID-PACT. Circulation. 2022;146(18):1344–56.
Article CAS PubMed PubMed Central Google Scholar
Wichmann D, Sperhake JP, Lütgehetmann M, Steurer S, Edler C, Heinemann A, et al. Autopsy findings and venous thromboembolism in patients with COVID-19: A prospective cohort study. Ann Intern Med. 2020;173(4):268–77.
Uaprasert N, Tangcheewinsirikul N, Rojnuckarin P, Patell R, Zwicker JI, Chiasakul T. Heparin-induced thrombocytopenia in patients with COVID-19: a systematic review and meta-analysis. Blood Adv. 2021;5(21):4521–34.
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