Aishwarya R, Abdullah CS, Morshed M, Remex NS, Bhuiyan MS. Sigmar1’s molecular, cellular, and biological functions in regulating cellular pathophysiology. Front Physiol. 2021;12: 705575.

Article  PubMed  PubMed Central  Google Scholar 

Alhmoud JF, Woolley JF, Al Moustafa AE, Mallei MI. DNA damage/repair management in cancers. In: Advances in medical biochemistry, genomics, physiology, and pathology. 2021;309–339.

Andonegui-Elguera MA, Cáceres-Gutiérrez RE, López-Saavedra A, Cisneros-Soberanis F, Justo-Garrido M, Díaz-Chávez J, Herrera LA. The roles of histone post-translational modifications in the formation and function of a mitotic chromosome. Int J Mol Sci. 2022;23(15):8704.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Apostoli AJ, Ailles L. Clonal evolution and tumor-initiating cells: new dimensions in cancer patient treatment. Crit Rev Clin Lab Sci. 2016;53(1):40–51.

Article  CAS  PubMed  Google Scholar 

Araldi RP, de Melo TC, Mendes TB, de Sa’ Junior PL, Nozima BHN, Ito ET, de Carvalho RF, de Souza EB, Stocco RD. Using the comet and micronucleus assays for genotoxicity studies: a review. Biomed Pharmacother. 2015;72:74–82.

Article  CAS  PubMed  Google Scholar 

Barra V, Fachinetti D. The dark side of centromeres: types, causes, and consequences of structural abnormalities implicating centromeric DNA. Nat Commun. 2018;9(1):4340.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bassey OB, Chukwu LO, Alimba GC. Cytogenetics of Chrysichthysnigrodigitatus as bioindicator of environmental pollution from two polluted lagoons. South West Niger J Genet Genome Res. 2019;6:047.

Google Scholar 

Bhat GR, Sethi I, Sadida HQ, Rah B, Mir R, Algehainy N, Albalawi IA, Masoodi T, Subbaraj GK, Jamal F, Singh M. Cancer cell plasticity: from cellular, molecular, and genetic mechanisms to tumor heterogeneity and drug resistance. Cancer Metastas Rev. 2024;43(1):197–228.

Article  Google Scholar 

Birkett N, Al-Zoughool M, Bird M, Baan RA, Zielinski J, Krewski D. Overview of biological mechanisms of human carcinogens. J Toxicol Environ Health Part B. 2019;22(7–8):288–359.

Article  CAS  Google Scholar 

Bonassi S, Fenech M. Micronuclei and their association with infertility, pregnancy complications, developmental defects, anaemias, inflammation, diabetes, chronic kidney disease, obesity, cardiovascular disease, neurodegenerative diseases and cancer. Mutat Res/Rev Mutat Res. 2019.

Bonora M, Missiroli S, Perrone M, Fiorica F, Pinton P, Giorgi C. Mitochondrial control of genomic instability in cancer. Cancers. 2021;13(8):1914.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Casalino L, Verde P. Multifaceted roles of DNA methylation in neoplastic transformation, from tumor suppressors to EMT and metastasis. Genes. 2020;11(8):922.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chappell G, Pogribny IP, Guyton KZ, Rusyn I. Epigenetic alterations induced by genotoxic occupational and environmental human chemical carcinogens: a systematic literature review. Mutat Res/Rev Mutat Res. 2016;768:27–45.

Article  CAS  PubMed  Google Scholar 

Chen M, Linstra R, van Vugt MA. Genomic instability, inflammatory signaling, and response to cancer immunotherapy. Biochim Biophys Acta Rev Cancer. 2022;1877(1): 188661.

Article  CAS  PubMed  Google Scholar 

Chen X, Agustinus AS, Li J, DiBona M, Bakhoum SF. Chromosomal instability as a driver of cancer progression. Nat Rev Genet. 2024;26:31.

Article  PubMed  Google Scholar 

Cinat D, Coppes RP, Barazzuol L. DNA damage-induced inflammatory microenvironment and adult stem cell response. Front Cell Dev Biol. 2021;9: 729136.

Article  PubMed  PubMed Central  Google Scholar 

Coppedè F, Migliore L. DNA damage in neurodegenerative diseases. Mutat Res/Fundam Mol Mech Mutagen. 2015;776:84–97.

Article  Google Scholar 

Cussenot O, Cancel-Tassin G, Rao SR, Woodcock DJ, Lamb AD, Mills IG, Hamdy FC. Aligning germline and somatic mutations in prostate cancer. Are genetics changing practice? BJU Int. 2023;132(5):472–84.

Article  CAS  PubMed  Google Scholar 

da Silva J. DNA damage induced by occupational and environmental exposure to miscellaneous chemicals. Mutat Res/Rev Mutat Res. 2016;770:170–82.

Article  PubMed  Google Scholar 

da Silva PMA. The Spindle Assembly Checkpoint: New Insights Into Its Function, Regulation, and Therapeutic Implications. PhD Dissertation, Universidade do Algarve (Portugal). 2017.

Devillers R, Dos Santos A, Destombes Q, Laplante M, Elowe S. Recent insights into the causes and consequences of chromosome mis-segregation. Oncogene. 2024; 1–12.

Dhillon VS, Deo P, Bonassi S, Fenech M. Lymphocyte micronuclei frequencies in skin, haematological, prostate, colorectal and esophageal cancer cases: a systematic review and meta-analysis. Mutat Res Rev Mutat Res. 2021;787: 108372.

Article  CAS  PubMed  Google Scholar 

Di Bona M, Bakhoum SF. Micronuclei and cancer. Cancer Discov. 2024;14(2):214–26.

Article  PubMed  PubMed Central  Google Scholar 

Donovan BMJ. Literature review: our current understanding of the mechanism underlying micronuclei-mediated mutagenesis in cancer (Doctoral dissertation, Harvard University). 2017.

Duro J, Nilsson J. SAC during early cell divisions: sacrificing fidelity over timely division, regulated differently across organisms: chromosome alignment and segregation are left unsupervised from the onset of development until checkpoint activity is acquired, varying from species to species. Bio Essays. 2021;43(3):2000174.

CAS  Google Scholar 

Espinosa-Sánchez A, Suárez-Martínez E, Sánchez-Díaz L, Carnero A. Therapeutic targeting of signaling pathways related to cancer stemness. Front Oncol. 2020;10:1533.

Article  PubMed  PubMed Central  Google Scholar 

Fenech M, Knasmueller S, Bolognesi C, Bonassi S, Holland N, Migliore L, Palitti F, Natarajan AT, Kirsch-Volders M. Molecular mechanisms by which in vivo exposure to exogenous chemical genotoxic agents can lead to micronucleus formation in lymphocytes in vivo and ex vivo in humans. Mutat Res Rev Mutat Res. 2016;770:12–25.

Article  CAS  PubMed  Google Scholar 

Fenech M, Knasmueller S, Bolognesi C, Holland N, Bonassi S, Kirsch-Volders M. Micronuclei as biomarkers of DNA damage, aneuploidy, inducers of chromosomal hypermutation and as sources of pro-inflammatory DNA in humans. Mutat Res Rev Mutat Res. 2020;786: 108342.

Article  CAS  PubMed  Google Scholar 

Fenech M, Knasmueller S, Knudsen LE, Kirsch-Volders M, Deo P, Franzke B, Stopper H, Andreassi MG, Bolognesi C, Dhillon VS, Laffon B, Wagner K, Bonassi S. Micronuclei and disease, special issue: aims, scope, and synthesis of outcomes. Mutat Res Rev Mutat Res. 2021;788: 108384. https://doi.org/10.1016/j.mrrev.2021.108384.

Article  CAS  PubMed  Google Scholar 

Feng B, Zheng J, Cai Y, Han Y, Han Y, Wu J, Feng J, Zheng K. An Epigenetic manifestation of Alzheimer’s disease: DNA methylation. ActasEspPsiquiatr. 2024;52(3):365–74. https://doi.org/10.62641/aep.v52i3.1595.

Article  Google Scholar 

Grypari IM, Tzelepi V, Gyftopoulos K. DNA damage repair pathways in prostate cancer: a narrative review of molecular mechanisms, emerging biomarkers and therapeutic targets in precision oncology. Int J Mol Sci. 2023;24(14):11418.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gumeni S, Evangelakou Z, Gorgoulis VG, Trougakos IP. Proteome stability as a key factor of genome integrity. Int J Mol Sci. 2017;18(10):2036.

Article  PubMed  PubMed Central  Google Scholar 

Guo X, Dai X, Wu X, Zhou T, Ni J, Xue J, Wang X. Understanding the birth of rupture-prone and irreparable micronuclei. Chromosoma. 2020;129:181–200.

Article  CAS  PubMed  Google Scholar 

Guo X, Ni J, Liang Z, Xue J, Fenech MF, Wang X. The molecular origins and pathophysiological consequences of micronuclei: new insights into an age-old problem. Mutat Res Rev Mutat Res. 2019;779:1–35. https://doi.org/10.1016/j.mrrev.2018.11.001.

Article  CAS  PubMed  Google Scholar 

Guo X, Dai X, Wu X, Cao N, Wang X. Small but strong: mutational and functional landscapes of micronuclei in cancer genomes. Int J Cancer. 2021;148(4):812–24.

Article  CAS  PubMed  Google Scholar 

Haberland VM, Magin S, Iliakis G, Hartwig A. Impact of manganese and chromate on specific DNA double-strand break repair pathways. Int J Mol Sci. 2023;24(12):10392.