Ahmadian M, Roshan VD, Aslani E, Stannard SR. Taurine supplementation has anti-atherogenic and anti-inflammatory effects before and after incremental exercise in heart failure. Ther Adv Cardiovasc Dis. 2017;11(7):185–94.
Article PubMed PubMed Central CAS Google Scholar
Aker S, Belosjorow S, Konietzka I, Duschin A, Martin C, Heusch G, Schulz R. Serum but not myocardial TNF-α concentration is increased in pacing-induced heart failure in rabbits. Am J Physiol Regul Integr Comp Physiol. 2003;285(2):R463–9.
Article PubMed CAS Google Scholar
Alhumaidha KA, Saleh DO, Abd El Fattah MA, El-Eraky WI, Moawad H. Cardiorenal protective effect of taurine against cyclophosphamide-induced toxicity in albino rats. Can J Physiol Pharmacol. 2016;94(2):131–9.
Article PubMed CAS Google Scholar
Azuma J, Sawamura A, Awata N, Ohta H, Hamaguchi T, Harada H, Takihara K, Hasegawa H, Yamagami T, Ishiyama T, et al. Therapeutic effect of taurine in congestive heart failure: a double-blind crossover trial. Clin Cardiol. 1985;8(5):276–82.
Article PubMed CAS Google Scholar
Azuma J, Sawamura A, Awata N. Usefulness of taurine in chronic congestive heart failure and its prospective application. Jpn Circ J. 1992;56(1):95–9.
Article PubMed CAS Google Scholar
Bai H, Li T, Yu Y, Zhou N, Kou H, Guo Y, Yang L, Yan P. Cytoprotective effects of taurine on heat-induced bovine mammary epithelial cells in vitro. Cells. 2021;10(2):258.
Article PubMed PubMed Central CAS Google Scholar
Barbiera A, Sorrentino S, Fard D, Lepore E, Sica G, Dobrowolny G, Tamagnone L, Scicchitano BM. Taurine administration counteracts aging-associated impingement of skeletal muscle regeneration by reducing inflammation and oxidative stress. Antioxidants. 2022;11(5):1016.
Article PubMed PubMed Central CAS Google Scholar
Barış VÖ, Gedikli E, Yersal N, Müftüoğlu S, Erdem A. Protective effect of taurine against doxorubicin-induced cardiotoxicity in rats: echocardiographical and histological findings. Amino Acids. 2019;51:1649–55.
Bartlett JJ, Trivedi PC, Yeung P, Kienesberger PC, Pulinilkunnil T. Doxorubicin impairs cardiomyocyte viability by suppressing transcription factor EB expression and disrupting autophagy. Biochem J. 2016;473(21):3769–89.
Article PubMed CAS Google Scholar
Belikova J, Lizogub V, Kuzminets A, Lavrenchuk I. Normalization of heart rate variability with taurine and meldonium complex in post-infarction patients with type 2 diabetes mellitus. J Med Life. 2019;12(3):290–5.
PubMed PubMed Central Google Scholar
Besse HC, Chen Y, Scheeren HW, Metselaar JM, Lammers T, Moonen CT, Hennink WE, Deckers R. A doxorubicin-glucuronide prodrug released from nanogels activated by high-intensity focused ultrasound liberated β-glucuronidase. Pharmaceutics. 2020;12(6):536.
Article PubMed PubMed Central CAS Google Scholar
Beyranvand MR, Khalafi MK, Roshan VD, Choobineh S, Parsa SA, Piranfar MA. Effect of taurine supplementation on exercise capacity of patients with heart failure. J Cardiol. 2011;57(3):333–7.
Caine JJ, Geracioti TD. Taurine, energy drinks, and neuroendocrine effects. Cleve Clin J Med. 2016;83(12):895–904.
Chaix MA, Parmar N, Kinnear C, Lafreniere-Roula M, Akinrinade O, Yao R, Miron A, Lam E, Meng G, Christie A, Manickaraj AK. Machine learning identifies clinical and genetic factors associated with anthracycline cardiotoxicity in pediatric cancer survivors. Cardio Oncology. 2020;2(5):690–706.
Chen H, Zhu J, Le Y, Pan J, Liu Y, Liu Z, Wang C, Dou X, Lu D. Salidroside inhibits doxorubicin-induced cardiomyopathy by modulating a ferroptosis-dependent pathway. Phytomedicine. 2022;99:153964.
Article PubMed CAS Google Scholar
Chesney RW. Taurine: its biological role and clinical implications. Adv Pediatr. 1985;32(1):1–42.
Article PubMed CAS Google Scholar
Chik MW, Hazalin NA, Singh GK. Regulation of phase I and phase II neurosteroid enzymes in the hippocampus of an Alzheimer’s disease rat model: a focus on sulphotransferases and UDP-glucuronosyltransferases. Steroids. 2022;184:109035.
Article PubMed CAS Google Scholar
Christidi E, Brunham LR. Regulated cell death pathways in doxorubicin-induced cardiotoxicity. Cell Death Dis. 2021;12(4):339.
Article PubMed PubMed Central CAS Google Scholar
Das J, Ghosh J, Manna P, Sil PC. Taurine suppresses doxorubicin-triggered oxidative stress and cardiac apoptosis in rat via up-regulation of PI3-K/Akt and inhibition of p53, p38-JNK. Biochem Pharmacol. 2011;81(7):891–909.
Article PubMed CAS Google Scholar
ErdogmusOzgen Z, Erdinc M, Kelle İ, Erdinc L, Nergiz Y. Protective effects of necrostatin-1 on doxorubicin-induced cardiotoxicity in rat heart. Hum Exp Toxicol. 2022;41:09603271211066066.
Fu LX, Waagstein F, Hjalmarson Å. A new insight into adriamycin-induced cardiotoxicity. Int J Cardiol. 1990;29(1):15–20.
Article PubMed CAS Google Scholar
Gagliarducci U. Sul trattamento delle cardiopatie ischemichie acute con taurina. Osservazioni cliniche su trenta casi [Treatment of acute ischemic heart disease using taurine. Clinical study of 30 cases]. Clin Ter. 1974 Feb 15;68(3):261–70.
Ghanim AM, Farag MR, Anwar MA, Ali NA, Hawas MA, Elsallab HM, Elhendawy WA, Basyouni LA, Refaey OA, Zaki KE, Ali NA. Taurine alleviates kidney injury in a thioacetamide rat model by mediating Nrf2/HO-1, NQO-1, and MAPK/NF-κB signaling pathways. Can J Physiol Pharmacol. 2022;100(4):352–60.
Article PubMed CAS Google Scholar
Ghosh S, Chitgupi U, Sunar U, Lovell JF. Chemophototherapeutic ablation of doxorubicin-resistant human ovarian tumor cells. Photochem Photobiol. 2023;99(2):844–9.
Article PubMed CAS Google Scholar
Gutteridge JM. Lipid peroxidation and possible hydroxyl radical formation stimulated by the self-reduction of a doxorubicin-iron (III) complex. Biochem Pharmacol. 1984;33(11):1725–8.
Article PubMed CAS Google Scholar
Hamaguchi T, Azuma J, Awata N, Ohta H, Takihara K, Harada H, Kishimoto S, Sperelakis N. Reduction of doxorubicin-induced cardiotoxicity in mice by taurine. Res Commun Chem Pathol Pharmacol. 1988;59(1):21–30.
Hamaguchi T, Azuma J, Harada H, Takahashi K, Kishimoto S, Schaffer SW. Protective effect of taurine against doxorubicin-induced cardiotoxicity in perfused chick hearts. Pharmacol Res. 1989;21(6):729–34.
Article PubMed CAS Google Scholar
Hegewisch S, Weh HJ, Hossfeld DK. TNF-induced cardiomyopathy. Lancet. 1990;335(8684):294–5.
Article PubMed CAS Google Scholar
Husain N, Mahmood R. Taurine attenuates Cr (VI)-induced cellular and DNA damage: an in vitro study using human erythrocytes and lymphocytes. Amino Acids. 2020;52(1):35–53.
Article PubMed CAS Google Scholar
Ibrahim Fouad G, Ahmed KA. Curcumin ameliorates doxorubicin-induced cardiotoxicity and hepatotoxicity via suppressing oxidative stress and modulating iNOS, NF-κB, and TNF-α in rats. Cardiovasc Toxicol. 2022;22(2):152–66.
Article PubMed CAS Google Scholar
Ito H, Miller SC, Billingham ME, Akimoto H, Torti SV, Wade R, Gahlmann R, Lyons G, Kedes L, Torti FM. Doxorubicin selectively inhibits muscle gene expression in cardiac muscle cells in vivo and in vitro. Proc Natl Acad Sci. 1990;87(11):4275–9.
Article PubMed PubMed Central CAS Google Scholar
Ito T, Muraoka S, Takahashi K, Fujio Y, Schaffer SW, Azuma J. Beneficial effect of taurine treatment against doxorubicin-induced cardiotoxicity in mice. In: Azuma Junichi, Schaffer Stephen W, Ito Takashi,
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