These authors contributed equally: Kristine Barlow-Stewart, Eliza Courtney.

Children’s Cancer Institute, Lowy Cancer Research Centre, UNSW, Kensington, NSW, Australia

Kristine Barlow-Stewart, Eliza Courtney, Mark Cowley, Noemi Fuentes Bolanos, Andrew J. Gifford, Marion K. Mateos, Mitali Manzur, Chelsea Mayoh, Mark Pinese, Ashleigh Sullivan, Toby Trahair, Vanessa Tyrrell, Meera Warby & David S. Ziegler

School of Clinical Medicine, UNSW Medicine and Health, UNSW, Kensington, NSW, Australia

Kristine Barlow-Stewart, Eliza Courtney, Mark Cowley, Noemi Fuentes Bolanos, Andrew J. Gifford, Marion K. Mateos, Mitali Manzur, Chelsea Mayoh, Mark Pinese, Ashleigh Sullivan, Toby Trahair, Vanessa Tyrrell, Meera Warby & David S. Ziegler

Kids Cancer Centre, Sydney Children’s Hospitals Network Randwick, Randwick, NSW, Australia

Kristine Barlow-Stewart, Eliza Courtney, Noemi Fuentes Bolanos, Marion K. Mateos, Matthew O’Connor, Toby Trahair, Katherine Tucker, Meera Warby & David S. Ziegler

Northern Clinical School, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia

Kristine Barlow-Stewart

Genetic Health Queensland, Royal Brisbane Women’s Hospital, Brisbane, QLD, Australia

Camron Ebzery & Di Milnes

Anatomical Pathology, NSW Heath Pathology, Prince of Wales Hospital, Randwick, NSW, Australia

Andrew J. Gifford

Australian Families 4 Genomics, Brisbane, QLD, Australia

Hazel Harden, Catherine Pitman & Elizabeth Pitman

Clinical Genetics, The Children’s Hospital at Westmead, Westmead, NSW, Australia

Sarah Josephi-Taylor

Department of Clinical Haematology, Oncology, Blood and Marrow Transplantation, Perth Children’s Hospital, Perth, WA, Australia

Rishi S. Kotecha

Leukaemia Translational Research Laboratory, Telethon Kids Cancer Centre, Telethon Kids Institute, University of Western Australia, Perth, WA, Australia

Rishi S. Kotecha

Curtin Medical School, Curtin University, Perth, WA, Australia

Rishi S. Kotecha

Faculty of Law, University of Tasmania, Hobart, TAS, Australia

Jane Nielsen & Carolyn Johnston

Women’s and Children’s Hospital, Adelaide, SA, Australia

Matthew O’Connor

Cancer Centre for Children, The Children’s Hospital at Westmead, Westmead, NSW, Australia

Bhavna Padhye

Kids Research, Children’s Cancer Research Unit, The Children’s Hospital at Westmead, Westmead, NSW, Australia

Bhavna Padhye

Hereditary Cancer Centre, Prince of Wales Hospital Nelune Comprehensive Cancer Centre, Randwick, NSW, Australia

Catherine Speechly & Katherine Tucker

Department of Oncology, Children’s Health Queensland Hospital and Health Service, South Brisbane, QLD, Australia

Ashleigh Sullivan

Starship Child Health, Auckland, New Zealand

Andrew Wood

Department of Molecular Medicine and Pathology, Faculty of Medical and Health Science, University of Auckland, Auckland, New Zealand

Andrew Wood