Chen HJ, Hu Y, Yao P, Ning D, Zhang YP, Wang ZG, Liu SL, Pang DW. Accurate and efficient lipoprotein detection based on the HCR-DNAzyme platform. Anal Chem. 2021;93(15):6128–34.
Article CAS PubMed Google Scholar
Liu X, Mao D, Song Y, Zhu L, Isak AN, Lu C, Deng G, Chen F, Sun F, Yang Y, Zhu X, Tan W. Computer-aided design of reversible hybridization chain reaction (CAD-HCR) enables multiplexed single-cell spatial proteomics imaging. Sci Adv. 2022;8(2):eabk0133.
Article CAS PubMed PubMed Central Google Scholar
Saisuk W, Suksamai C, Srisawat C, Yoksan S, Dharakul T. The helper oligonucleotides enable detection of folded single-stranded DNA by lateral flow immunoassay after HCR signal amplification. Talanta. 2022;248: 123588.
Article CAS PubMed Google Scholar
Xiao Q, Liu S, Wang Y, Li H, Yang M, Fang Y, Chen S, Huang S. A high-performance electrochemical analysis platform for ultrasensitive detection of HTLV-1 DNA: integrating cascade signal amplification with λ-exonuclease-assisted target recycling and enzyme catalysis. J Anal Test. 2024;8(3):361–73.
Wu D, Wang YJ, Wang QQ, Li T, Guo YS. Detection of extracellular vesicles based on aptamer recognition and hybridization chain reaction amplification. Chin J Anal Lab. 2024;43(2):266–73.
Wang Y, Zhao X, Zhang M, Sun X, Bai J, Peng Y, Li S, Han D, Ren S, Wang J, Han T, Gao Y, Ning B, Gao Z. A fluorescent amplification strategy for high-sensitive detection of 17 β-estradiol based on EXPAR and HCR. Anal Chim Acta. 2020;1116:1–8.
Article CAS PubMed Google Scholar
Li G, Qi X, Wu J, Wan X, Wang T, Liu Y, Chen Y, Xia Y. Highly stable electrochemical sensing platform for the selective determination of pefloxacin in food samples based on a molecularly imprinted-polymer-coated gold nanoparticle/black phosphorus nanocomposite. Food Chem. 2024;436: 137753.
Article CAS PubMed Google Scholar
Yu C, Wang Y, Wu R, Zhu Z, Li B. Study on the functionalization and signaling efficiency of the hybridization chain reaction using traditional and single molecular characterizations. ACS Appl Bio Mater. 2021;4(4):3649–57.
Article CAS PubMed Google Scholar
Wang T, Xia Y, Wan X, Zhang Y, Chen N, Jin Y, Li G. A facile and efficient voltammetric sensor for marbofloxacin detection based on zirconium-based metal-organic framework UiO-66/nitrogen-doped graphene nanocomposite. Microchem J. 2024;201: 110673.
Zhou R, Zeng Z, Sun R, Liu W, Zhu Q, Zhang X, Chen C. Traditional and new applications of the HCR in biosensing and biomedicine. Analyst. 2021;146(23):7087–103.
Article CAS PubMed Google Scholar
Chen X, Huang C, Nie F, Hu M. Enzyme-free and sensitive method for single-stranded nucleic acid detection based on CHA and HCR. Anal Methods. 2023;15(34):4243–51.
Article CAS PubMed Google Scholar
Bai Y, Tan S, Sheng Y, Gu Y, Wu H, Li B, Liu Y. A high-affinity methyl-CpG-binding protein for endonuclease-free and label-free DNA methyltransferase activity detection. J Anal Test. 2024;8(3):327–34.
Wang J, Shimada N, Maruyama A. Cationic copolymer-augmented DNA hybridization chain reaction. ACS Appl Mater Interfaces. 2022;14(34):39396–403.
Article CAS PubMed Google Scholar
Mo L, Liang D, Qin R, Mo M, Yang C, Lin W. Three-dimensional CHA-HCR system using DNA nanospheres for sensitive and rapid imaging of miRNA in live cells and tissues. Anal Chem. 2023;95(31):11777–84.
Article CAS PubMed Google Scholar
Sun H, Yao F, Su Z, Kang XF. Hybridization chain reaction (HCR) for amplifying nanopore signals. Biosens Bioelectron. 2020;150: 111906.
Article CAS PubMed Google Scholar
Kim KT, Angerani S, Winssinger N. A minimal hybridization chain reaction (HCR) system using peptide nucleic acids. Chem Sci. 2021;12(23):8218–23.
Article CAS PubMed PubMed Central Google Scholar
Qiu F, Gan X, Yao J, Jiang B, Yuan R, Xiang Y. CRISPR/Cas12a-derived sensitive electrochemical biosensing of NF-κB p50 based on hybridization chain reaction and DNA hydrogel. Biosens Bioelectron. 2022;216: 114665.
Article CAS PubMed Google Scholar
Shainer I, Kuehn E, Laurell E, Al Kassar M, Mokayes N, Sherman S, Larsch J, Kunst M, Baier H. A single-cell resolution gene expression atlas of the larval zebrafish brain. Sci Adv. 2023;9(8):eade9909.
Article CAS PubMed PubMed Central Google Scholar
Wu J, Lv J, Zheng X, Wu ZS. Hybridization chain reaction and its applications in biosensing. Talanta. 2021;234: 122637.
Article CAS PubMed Google Scholar
Luo X, Kang T, Zhu J, Wu P, Cai C. Sensitivity-improved SERS detection of methyltransferase assisted by plasmonically engineered nanoholes array and hybridization chain reaction. ACS Sens. 2020;5(11):3639–48.
Article CAS PubMed Google Scholar
Duan Y, Glazier R, Bazrafshan A, Hu Y, Rashid SA, Petrich BG, Ke Y, Salaita K. Mechanically triggered hybridization chain reaction. Angew Chem Int Ed Engl. 2021;60(36):19974–81.
Article CAS PubMed PubMed Central Google Scholar
Zhang L, Peng J, Hong MF, Chen JQ, Liang RP, Qiu JD. Cobalt phosphide nanowires for fluorometric detection and in-situ imaging of telomerase activity via hybridization chain reactions. Mikrochim Acta. 2019;186(5):309.
Liang Y, Zhang C. A novel PCR-free and label-free cloth-based DNA sensor for sensitive and rapid detection of Escherichia coli. Anal Chim Acta. 2023;1239: 340630.
Article CAS PubMed Google Scholar
Choi HMT, Schwarzkopf M, Fornace ME, Acharya A, Artavanis G, Stegmaier J, Cunha A, Pierce NA. Third-generation in situ hybridization chain reaction: multiplexed, quantitative, sensitive, versatile, robust. Development. 2018;145(12): dev165753.
Article PubMed PubMed Central Google Scholar
Hosseinzadeh E, Ravan H, Mohammadi A, Pourghadamyari H. Colorimetric detection of miRNA-21 by DNAzyme-coupled branched DNA constructs. Talanta. 2020;216: 120913.
Article CAS PubMed Google Scholar
Jia HY, Zhao HL, Wang T, Chen PR, Yin BC, Ye BC. A programmable and sensitive CRISPR/Cas12a-based MicroRNA detection platform combined with hybridization chain reaction. Biosens Bioelectron. 2022;211: 114382.
Article CAS PubMed Google Scholar
Guo J, Mingoes C, Qiu X, Hildebrandt N. Simple, amplified, and multiplexed detection of MicroRNAs using time-gated FRET and hybridization chain reaction. Anal Chem. 2019;91(4):3101–9.
Article CAS PubMed Google Scholar
Li M, Zhang T, Zhang Y. Ultrasensitive electrochemical sensing platform for miRNA-21 detection based on manganese dioxide-gold nanoparticle nanoconjugates coupled with hybridization chain reaction and horseradish peroxidase signal amplification. Analyst. 2023;148(9):2180–8.
Article CAS PubMed Google Scholar
Nie Y, Yuan X, Zhang P, Chai YQ, Yuan R. Versatile and ultrasensitive electrochemiluminescence biosensor for biomarker detection based on nonenzymatic amplification and aptamer-triggered emitter release. Anal Chem. 2019;91(5):3452–8.
Article CAS PubMed Google Scholar
Kim J, Shim JS, Han BH, Kim HJ, Park J, Cho IJ, Kang SG, Kang JY, Bong KW, Choi N. Hydrogel-based hybridization chain reaction (HCR) for detection of urinary exosomal miRNAs as a diagnostic tool of prostate cancer. Biosens Bioelectron. 2019;192:113504.
Zhang W, Hao W, Liu X, Sun X, Yan J, Wang Y. Visual detection of miRNAs using enzyme-free amplification reactions and ratiometric fluorescent probes. Talanta. 2020;219: 121332.
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