Aicardi G (2018) Young blood plasma administration to fight Alzheimer’s disease? Rejuvenation Res 21:178–181. https://doi.org/10.1089/rej.2017.1940

Article  PubMed  Google Scholar 

Allahverdi H (2024) Exploring the therapeutic potential of plasma from intermittent fasting and untreated rats on aging-induced liver damage. J Cell Mol Med 28:e18456. https://doi.org/10.1111/jcmm.18456

Article  PubMed  PubMed Central  CAS  Google Scholar 

Asmaz ED, Seyidoglu N (2022) The prevention role of Spirulina platensis (Arthrospira platensis) on intestinal health. Food Sci Hum Wellness 11:1342–1346. https://doi.org/10.1016/j.fshw.2022.04.027

Article  CAS  Google Scholar 

Asmaz ED, Yesilbag D, Odabasi F, Zık B (2022) Synergistic effect of feed additives on cell proliferation and morphology in quail (Coturnix coturnix Japonica) duodenum. J Hell Vet Med Soc 73:4575–4582

Article  Google Scholar 

Baht GS, Silkstone D, Vi L, Nadesan P, Amani Y, Whetstone H, Wei Q, Alman BA (2015) Exposure to a youthful circulaton rejuvenates bone repair through modulation of β-catenin. Nat Commun 6:7131. https://doi.org/10.1038/ncomms813

Article  PubMed  CAS  Google Scholar 

Barker N, VanEs JH, Kuipers J, Kujala P, VanDenBorn M, Cozijnsen M, Haegebarth A, Korving J, Begthel H, Peters PJ, Clevers H (2007) Identification of stem cells in small intestine and colon by marker gene Lgr5. Nature 449:1003–1007. https://doi.org/10.1038/nature06196

Article  PubMed  CAS  Google Scholar 

Beharka AA, Paiva S, Leka LS, Ribaya-Mercado JD, Russell RM, Nibkin Meydani S (2001) Effect of age on the gastrointestinal-associated mucosal immune response of humans. J Gerontol A Biol Sci Med Sci 56:B218–B223. https://doi.org/10.1093/gerona/56.5.b218

Article  PubMed  CAS  Google Scholar 

Bonis V, Rossell C, Gehart H (2021) The Intestinal epithelium- fluid fate and rigid structure from crypt bottom to villus tip. Front Cell Dev Biol 9:661931. https://doi.org/10.3389/fcell.2021.66193

Article  PubMed  PubMed Central  Google Scholar 

Boursier L, Dunn-Walters DK, Spencer J (1999) Characteristics of IgVH genes used by human intestinal plasma cells from childhood. Immunology 97:558–564. https://doi.org/10.1046/j.1365-2567

Article  PubMed  PubMed Central  CAS  Google Scholar 

Calik A, Ergün A (2015) Effect of lactulose supplementation on growth performance, intestinal histomorphology, cecal microbial population, and short-chain fatty acid composition of broiler chickens. Poult Sci 94:2173–2182. https://doi.org/10.3382/ps/pev182

Article  PubMed  CAS  Google Scholar 

Castellano JM, Mosher KI, Abbey RJ, McBride AA, James ML, Berdnik D, Shen JC, Zou B, Xie XS, Tingle M, Hinkson IV, Angst MS, Wyss-Coray T (2017) Human umbilical cord plasma proteins revitalize hippocampal function in aged mice. Nature 544:488–492. https://doi.org/10.1038/nature22067

Article  PubMed  PubMed Central  CAS  Google Scholar 

Ceylani T (2023) Effect of SCD probiotics supplemented with tauroursodeoksikolik asit (TUDCA) application on the aged rat gut microbiota composition. J Appl 134(5):lxad092

Google Scholar 

Ceylani T, Teker HT (2022) The effect of young blood plasma administration on gut microbiota in middle-aged rats. Arch Microbiol 204:541. https://doi.org/10.1007/s00203-022-03154-8

Article  PubMed  CAS  Google Scholar 

Ceylani T, Teker HT, Keskin S, Samgane G, Acikgoz E, Gurbanov R (2023a) The rejuvenating influence of young plasma on aged intestine. J Cell Mol Med 27:2804–2816. https://doi.org/10.1111/jcmm.17926

Article  PubMed  PubMed Central  Google Scholar 

Ceylani T, Allahverdi H, Teker HT (2023b) Role of age-related plasma in the diversity of gut bacteria. Arch Gerontol Geriatr 111:105003. https://doi.org/10.1016/j.archger.2023.105003

Article  PubMed  CAS  Google Scholar 

Conboy IM, Conboy MJ, Wagers AJ, Girma ER, Weissman IL, Rando TA (2005) Rejuvenation of aged progenitor cells by exposure to a young systemic environment. Nature 433:760–764. https://doi.org/10.1038/nature03260

Article  PubMed  CAS  Google Scholar 

Conese M, Carbone A, Beccia E, Angiolillo A (2017) The Fountain of Youth: A Tale of Parabiosis, Stem Cells, and Rejuvenation. Open Med (Warsaw, Poland) 12:376–383. https://doi.org/10.1515/med-2017-0053

Article  CAS  Google Scholar 

Crossmon G (1937) A Modification of Mallory’s Connective Tissue Stain with a Discussion of the Principles Involved. Anat Rec 69:33–38

Article  Google Scholar 

de Magalhães JP, Stevens M, Thornton D (2017) The business of anti-aging science. Trends Biotechnol 35:1062–1073. https://doi.org/10.1016/j.tibtech.2017.07.004

Article  PubMed  CAS  Google Scholar 

Fernandez MI, Pedron T, Tournebize R, Olivo-Marin JC, Sansonetti PJ, Phalipon A (2003) Anti-inflammatory role for intracellular dimeric immunoglobulin a by neutralization of lipopolysaccharide in epithelial cells. Immunity 18:739–749. https://doi.org/10.1016/s1074-7613(03)00122-5

Article  PubMed  CAS  Google Scholar 

Florian MC, Nattamai KJ, Dörr K, Marka G, Uberle B, Vas V, Eckl C, Andrä I, Schiemann M, Oostendorp RA, Scharffetter-Kochanek K, Kestler HA, Zheng Y, Geiger H (2013) A canonical to non-canonical Wnt signalling switch in haematopoietic stem-cell ageing. Nature 503:392–396. https://doi.org/10.1038/nature12631

Article  PubMed  PubMed Central  CAS  Google Scholar 

Golby SJC, Spencer J (2002) Where do IgA plasma cells in the gut come from? Gut 51:150–151. https://doi.org/10.1136/gut.51.2.150

Article  PubMed  PubMed Central  CAS  Google Scholar 

Guler S, Asmaz ED, Kayapunar NV, Işbilir I, Cengz ŞŞ, Sanlı YD, AB, Gultepe EE (2022) Effects of dietary calcium, phosphorus and microbial phytase on intestinal morphology in laying hens. Turkish J Vet Anim Sci 46:293–303

Article  CAS  Google Scholar 

Gupta P, Hu Z, Kopparapu PK, Deshmukh M, Sághy T, Mohammad M, Jin T, Engdahl C (2023) The impact of TLR2 and aging on the humoral immune response to Staphylococcus aureus bacteremia in mice. Sci Rep 13:8850. https://doi.org/10.1038/s41598-023-35970-3

Article  PubMed  PubMed Central  CAS  Google Scholar 

Horowitz AM, Fan X, Bieri G, Smith LK, Sanchez-Diaz CI, Schroer AB, Gontier G, Casaletto KB, Kramer JH, Williams KE, Villeda SA (2020) Blood factors transfer beneficial effects of exercise on neurogenesis and cognition to the aged brain. Science 369:167–173. https://doi.org/10.1126/science.aaw2622

Article  PubMed  PubMed Central  CAS  Google Scholar 

Kang JS, Yang YR (2020) Circulating plasma factors involved in rejuvenation. Aging 12:23394–23408

PubMed  PubMed Central  CAS  Google Scholar 

Katsimpardi L, Litterman NK, Schein PA, Miller CM, Loffredo FS, Wojtkiewicz GR, Chen JW, Lee RT, Wagers AJ, Rubin LL (2014) Vascular and neurogenic rejuvenation of the aging mouse brain by young systemic factors. Science 344:630–634. https://doi.org/10.1126/science.1251141

Article  PubMed  PubMed Central  CAS  Google Scholar 

Kawanishi H, Ajitsu S, Mirabella S (1990) Impaired humoral immune responses to mycobacterial antigen in aged murine gut-associated lymphoid tissues. Mech Ageing Dev 54:143–161. https://doi.org/10.1016/0047-6374(90)90062-k

Article  PubMed  CAS  Google Scholar 

Lehallier B, Gate D, Schaum N, Nanasi T, Lee SE, Yousef H, Moran Losada P, Berdnik D, Keller A, Verghese J, Sathyan S, Franceschi C, Milman S, Barzilai N, Wyss-Coray T (2019) Undulating changes in human plasma proteome profiles across the lifespan. Nat Med 25:1843–1850. https://doi.org/10.1038/s41591-019-0673-2

Article  PubMed  PubMed Central