P.R. Guru, R.K. Kar, A.K. Nayak, S. Mohapatra. A comprehensive review on pharmaceutical uses of plant-derived biopolysaccharides. International Journal of Biological Macromolecules 233 (2023) 123454. https://doi.org/10.1016/j.ijbiomac.2023.123454.

F.J. Acebedo-Martínez, A. Domínguez-Martín, C. Alarcón-Payer, A. Sevillano-Páez, C. Verdugo-Escamilla, J.M. González-Pérez, F. Martínez-Checa, D. Choquesillo-Lazarte. Enhanced NSAIDs Solubility in Drug–Drug Formulations with Ciprofloxacin. International Journal of Molecular Sciences 24 (2023) 3305. https://doi.org/10.3390/ijms24043305.

D. Zhou, J.N. Barney, G.E. Welbaum. Production, composition, and ecological function of sweet-basil-seed mucilage during hydration. Horticulturae 8 (2022) 327. https://doi.org/10.3390/horticulturae8040327

D. Tripathi, D.K. Sharma, J. Sahoo, S.K. Raman. Enhanced Solubility of Meloxicam with Sodium Benzoate Hydrotrope: Ecofriendly Approach for Improved Topical Drug Delivery. Indian Journal of Pharmaceutical Education and Research 56 (2022) 1052-1062. https://doi.org/10.5530/ijper.56.4.186.

A. Kapoor, S.K. Mishra, D.K. Verma, P. Pandey. Chemical penetration enhancers for transdermal drug delivery system. Journal of Drug Delivery and Therapeutics 8 (2018) 62-66. https://doi.org/10.22270/jddt.v8i5-s.1952.

N. Chaudhary, D. Tripathi, A.K. Rai. A technical approach of solubility enhancement of poorly soluble drugs: Liquisolid technique. Current Drug Delivery 17 (2020) 638-650. https://doi.org/10.2174/1567201817666200516155733.

D. Tripathi, N. Chaudhary, D.K. Sharma, J. Sahoo. An attempt to applying hydrotropy technique for titrimetric estimation of ketoprofen using sodium salicylate as hydrotrope. Research Journal of Pharmacy and Technology 14 (2021) 2277-2279. https://doi.org/10.52711/0974-360X.2021.00402.

D. Tripathi, M. Srivastava, K. Rathour, A.K. Rai, P. Wal, J. Sahoo, R.K. Tiwari, P. Pandey. A promising approach of dermal targeting of antipsoriatic drugs via engineered nanocarriers drug delivery systems for tackling psoriasis. Drug Metabolism and Bioanalysis Letters Formerly: Drug Metabolism Letters 16 (2023) 89-104. https://doi.org/10.2174/2949681016666230803150329.

D. Tripathi, B. Manjunatha Prabhu, J. Sahoo, J. Kumari. Navigating the Solution to Drug Formulation Problems at Research and Development Stages by Amorphous Solid Dispersion Technology. (2023). https://doi.org/10.2174/0126673878271641231201065151.

Y. Ale, N. Nainwal, M. Butola, S. Rana, S. Kala, V. Rawal, V. Jakhmola. Formulation and Characterization of Inter-Penetrating Network of Isabgol Husk Mucilage for Modified Release of Diclofenac Sodium. Ind. J. Pharm. Edu. Res 57 (2023) 703-710. https://doi.org/10.5530/ijper.57.3.85.

V.D. Prajapati, G.K. Jani, J.R. Kapadia. Current knowledge on biodegradable microspheres in drug delivery. Expert opinion on drug delivery 12 (2015) 1283-1299. https://doi.org/10.1517/17425247.2015.1015985.

P. Pandey, P.C. Gupta, S.J.E.J.o.P. Yadav, M. Research. Solid lipid nanoparticle: a potential approach in drug delivery system. 5 (2018) 225-236.

D. Roura Padrosa, V. De Vitis, M.L. Contente, F. Molinari, F. Paradisi. Overcoming water insolubility in flow: enantioselective hydrolysis of Naproxen Ester. Catalysts 9 (2019) 232. https://doi.org/10.3390/catal9030232.

P. Pandey, D. Kumar Arya, M. Kumar Ramar, K. Chidambaram, P.S. Rajinikanth. Engineered nanomaterials as an effective tool for HER2+ breast cancer therapy. Drug Discovery Today (2022). https://doi.org/10.1016/j.drudis.2022.06.007.

K. Lavudi, S.M. Nuguri, P. Pandey, R.R. Kokkanti, Q.-E. Wang. ALDH and cancer stem cells: Pathways, challenges, and future directions in targeted therapy. Life Sciences (2024) 123033.

A. Nanda, P. Pandey, P. Rajinikanth, N. Singh. Revolution of nanotechnology in food packaging: Harnessing electrospun zein nanofibers for improved preservation-A review. International Journal of Biological Macromolecules (2024) 129416. https://doi.org/10.1016/j.ijbiomac.2024.129416.

P. Pandey, D.K. Arya, P. Deepak, D. Ali, S. Alarifi, S. Srivastava, A. Lavasanifar, P.S. Rajinikanth. αvβ3 Integrin and Folate-Targeted pH-Sensitive Liposomes with Dual Ligand Modification for Metastatic Breast Cancer Treatment. Bioengineering 11 (2024) 800.

T. Wang, E. Fleming, Y. Luo. An overview of the biochemistry, synthesis, modification, and eva¬lu-ation of mucoadhesive polymeric nanoparticles for oral delivery of bioactive compounds. Advanced Composites and Hybrid Materials 6 (2023) 6. https://doi.org/10.1007/s42114-022-00586-0.

J. Benfica, A.C. Martins, G. Peréz-Sanchéz, N. Schaeffer, J.A. Coutinho. Exploring the impact of sodium salts on hydrotropic solubilization. Physical Chemistry Chemical Physics 25 (2023) 26327-26340. https://doi.org/10.1039/D3CP02034G

N. Nakhonchai, N. Prompila, K. Ponhong, W. Siriangkhawut, J. Vichapong, S.-a. Supharoek. Green hairy basil seed mucilage biosorbent for dispersive solid phase extraction enrichment of tetracyclines in bovine milk samples followed by HPLC analysis. Talanta 271 (2024) 125645. https://doi.org/10.1016/j.talanta.2024.125645.

S. Khan, P.S. Gangane, D.K. Mahapatra, N.M. Mahajan. Natural and synthetic polymers assisted development of lurasidone hydrochloride intranasal mucoadhesive microspheres. Indian J Pharm Edu Res 54 (2020) 213-222. https://doi.org/10.5530/ijper.54.1.25.

F. Kurd, M. Fathi, H. Shekarchizadeh. Basil seed mucilage as a new source for electrospinning: Production and physicochemical characterization. International Journal of Biological Macromolecules 95 (2017) 689-695. https://doi.org/10.1016/j.ijbiomac.2016.11.116

S. Mehrotra, P.K. Bg, P.G. Nayak, A. Joseph, J. Manikkath. Recent Progress in the Oral Delivery of Therapeutic Peptides and Proteins: Overview of Pharmaceutical Strategies to Overcome Absorption Hurdles. Advanced Pharmaceutical Bulletin 14 (2024) 11. https://doi.org/10.34172/apb.2024.009.

S. Weisman. Naproxen for post-operative pain. Journal of Pharmacy & Pharmaceutical Sciences 24 (2021) 62-70. https://doi.org/10.18433/jpps31629.

P. Singh, G. Mishra, S.C. Dinda. Natural excipients in pharmaceutical formulations. Evidence Based Validation of Traditional Medicines: A comprehensive Approach (2021) 829-869. https://doi.org/10.1007/978-981-15-8127-4_51.

M.-W. Ha, S.-M. Paek. Recent advances in the synthesis of ibuprofen and naproxen. Molecules 26 (2021) 4792. https://doi.org/10.3390/molecules26164792.

P.P. Ige, R.R. Badgujar, P.P. Nerkar, H.S. Mahajan, R.O. Sonawane, S.J. Surana. Study of physicochemical properties of flutamide-loaded Ocimum basilicum microspheres with ex vivo mucoadhesion and in vitro drug release. Particulate Science and Technology 36 (2018) 583-591. https://doi.org/10.1080/02726351.2016.1278293.

M.S. Hosseini, M.R. Nabid. Synthesis of chemically crosslinked hydrogel films based on basil seed (Ocimum basilicum L.) mucilage for wound dressing drug delivery applications. International Journal of Biological Macromolecules 163 (2020) 336-347. https://doi.org/10.1016/j.ijbiomac.2020.06.252.

N. Thessrimuang, J. Prachayawarakorn. Development, modification and characterization of new biodegradable film from basil seed (Ocimum basilicum L.) mucilage. Journal of the Science of Food and Agriculture 99 (2019) 5508-5515. https://doi.org/10.1002/jsfa.9812.

V. Singh, D. Srivastava, P. Pandey, M. Kumar, S. Yadav, D. Kumar, R.V.J.J.o.D.D. Kumar, Thera¬pe-utics. Characterization, antibacterial and anticancer study of silk fibroin hydrogel. 13 (2023) 21-31.

M.Z. Ahmad, S. Akhter, I. Ahmad, A. Singh, M. Anwar, M. Shamim, F.J. Ahmad. In vitro and in vivo evaluation of Assam Bora rice starch-based bioadhesive microsphere as a drug carrier for colon targeting. Expert opinion on drug delivery 9 (2012) 141-149. https://doi.org/10.1517/17425247.2012.633507.

A.K. Nayak, D. Pal, J. Pradhan, M.S. Hasnain. Fenugreek seed mucilage-alginate mucoadhesive beads of metformin HCl: Design, optimization and evaluation. International Journal of Biological Macromolecules 54 (2013) 144-154. https://doi.org/10.1016/j.ijbiomac.2012.12.008.

A.K. Nayak, D. Pal, K. Santra. Plantago ovata F. Mucilage‐Alginate Mucoadhesive Beads for Controlled Release of Glibenclamide: Development, Optimization, and In Vitro-In Vivo Evaluation. Journal of Pharmaceutics 2013 (2013) 151035. https://doi.org/10.1155/2013/151035.

S.S. Palakurthi, N.B. Charbe, S.Y.R. Phillips, D.L. Alge, D. Lu, S. Palakurthi. Development of optimal in vitro release and permeation testing method for rectal suppositories. International Journal of Pharmaceutics 640 (2023) 123042. https://doi.org/10.1016/j.ijpharm.2023.123042.

Y. Jiao, S. Xie, A. Baseer, F. Ud-Din. Rectal administration of Celecoxib liquid suppositories with enhanced bioavailability and safety in rats. Current Drug Delivery 20 (2023) 201-210. https://doi.org/10.2174/1567201819666220513091015.

A. Saleem, F. ud Din, Z. Ali, F. Zahid, A.H. Alamri, A.A. Lahiq, T. Alqahtani, H.M. Alharbi. Development and evaluation of regorafenib loaded liquid suppository for rectal delivery: In vitro, in vivo analyses. Journal of Drug Delivery Science and Technology 91 (2024) 105239. https://doi.org/10.1016/j.jddst.2023.105239.

N. Srikhao, K. Chirochrapas, N. Kwansanei, P. Kasemsiri, A. Ounkaew, M. Okhawilai, C. Likitaporn, S. Theerakulpisut, H. Uyama. Multi-responsive optimization of novel pH-sensitive hydrogel beads based on basil seed mucilage, alginate, and magnetic particles. Gels 8 (2022) 274. https://doi.org/10.3390/gels8050274.

B.A. Lodhi, A. Abbas, M.A. Hussain, S.Z. Hussain, M. Sher, I. Hussain. Design, characterization and appraisal of chemically modified polysaccharide based mucilage from Ocimum basilicum (basil) seeds for the removal of Cd (II) from spiked high-hardness ground water. Journal of Molecular Liquids 274 (2019) 15-24. https://doi.org/10.1016/j.molliq.2018.10.056.

A. Raj, R.M. Rego, K.V. Ajeya, H.-Y. Jung, M.D. Kurkuri. Basil seeds loaded with MOFs as an eco-friendly and sustainable adsorbent for efficient removal of hazardous organic pollutants from water. Separation and Purification Technology 330 (2024) 125370. https://doi.org/10.1016/j.seppur.2023.125370.

R.A. Patil, P.L. Pingale, S.V. Amrutkar. Comparative Effects of Ocimum tenuiflorum and Ocimum basilicum on Isoniazid Microsphere Formulation Characteristics Prepared by Different Methods. Current Trends in Biotechnology and Pharmacy 16 (2022) 78-86. https://doi.org/10.5530/ctbp.2022.3s.66.

D. Pal, A.K. Nayak. Novel tamarind seed polysaccharide-alginate mucoadhesive microspheres for oral gliclazide delivery: in vitro–in vivo evaluation. Drug Delivery 19 (2012) 123-131. https://doi.org/10.3109/10717544.2012.657717.

S. Nazir, I.A. Wani. Functional characterization of basil (Ocimum basilicum L.) seed mucilage. Bioactive Carbohydrates and Dietary Fibre 25 (2021) 100261. https://doi.org/10.1016/j.bcdf.2021.100261.

A. Mahmood, A. Erum, S. Mumtaz, U.R. Tulain, N.S. Malik, M.S. Alqahtani. Preliminary investigation of Linum usitatissimum mucilage-based hydrogel as possible substitute to synthetic polymer-based hydrogels for sustained release oral drug delivery. Gels 8 (2022) 170. https://doi.org/10.3390/gels8030170.

H.K. Solanki, D.A. Shah. Formulation optimization and evaluation of probiotic Lactobacillus sporogenes-loaded sodium alginate with carboxymethyl cellulose mucoadhesive beads using design expert software. Journal of Food Processing 2016 (2016). https://doi.org/10.1155/2016/6041671.

M. Rachpirom, W. Pichayakorn, P. Puttarak. Box-Behnken design to optimize the crosslinked sodium alginate/mucilage/Aloe vera film: Physical and mechanical studies. International Journal of Biological Macromolecules 246 (2023) 125568. https://doi.org/10.1016/j.heliyon.2023.e17807.

M.d.J. Perea-Flores, H.F. Aguilar-Morán, G. Calderón-Domínguez, A.B. García-Hernández, M. Díaz-Ramírez, H.E. Romero-Campos, A.D.J. Cortés-Sánchez, M.d.l.P. Salgado-Cruz. Entrapment efficiency (EE) and release mechanism of rhodamine b encapsulated in a mixture of chia seed mucilage and sodium alginate. Applied Sciences 13 (2023) 1213. https://doi.org/10.3390/app13021213.

S. Noureen, S. Noreen, S.A. Ghumman, F. Batool, H. Hameed, S. Hasan, F. Noreen, M.A. Elsherif, S.N.A. Bukhari. Prunus armeniaca gum-alginate polymeric microspheres to enhance the bioavailability of tramadol hydrochloride: formulation and evaluation. Pharmaceutics 14 (2022) 916. https://doi.org/10.3390/pharmaceutics14050916.

S. Tantiwatcharothai, J. Prachayawarakorn. Characterization of an antibacterial wound dressing from basil seed (Ocimum basilicum L.) mucilage-ZnO nanocomposite. International Journal of Biological Macromolecules 135 (2019) 133-140. https://doi.org/10.1016/j.ijbiomac.2019.05.118.

N. Hussain, I. Ishak, M.F. Abdullah, A. Abd Rauh, N. Azhar. Water soluble hydrocolloid from basil seed (Ocimum basilicum L.) mucilage. Malaysian Applied Biology 48 (2019) 97-101. https://jms.mabjournal.com/index.php/mab/article/view/1905 (Accessed 17. 08. 2024)

H. Gorges, A. Kovalev, S.N. Gorb. Structure, mechanical and adhesive properties of the cellulosic mucilage in Ocimum basilicum seeds. Acta Biomaterialia 184 (2024) 286-295. https://doi.org/10.1016/j.actbio.2024.06.045.

S.F. Wirtu, A.K. Mishra, L.T. Jule, K. Ramaswamy. Ocimum basilicum and Ocimum americanum: A Systematic Literature Review on Chemical Compositions and Antimicrobial Properties. Natural Product Communications 19 (2024) 1934578X241247640. https://doi.org/10.1177/1934578X241247640.

B.S. Patil, H.S. Mahajan, S.J. Surana. Development of suppositories containing flutamide-loaded alginate-tamarind microparticles for rectal administration: in vitro and in vivo studies. Chemical and Pharmaceutical Bulletin 63 (2015) 851-857. https://doi.org/10.1248/cpb.c15-00250.

A. Kumar, N. Bharath, M. Rao, P. Venkatesh, D. Hepcykalarani, R. Prema. A review on mucoadhesive drug delivery systems. Research Journal of Pharmaceutical Dosage Forms and Technology 11 (2019) 280-287. https://doi.org/10.5958/0975-4377.2019.00047.8.

K. Pathak, R. Malviya. Introduction, theories and mechanisms of bioadhesion. Bioadhesives in Drug Delivery (2020) 1-27. https://doi.org/10.1002/9781119640240.ch1.

S. Rhushikesh, S. Suresh. A Review on Mucoadhesive Drug Delivery System. Int. J. Res. Anal. Rev 7 (2020) 793-808. https://doi.org/http://dx.doi.org/10.37022/jiaps.v7i1.278.

I.S. Bayer. Recent advances in mucoadhesive interface materials, mucoadhesion characterization, and technologies. Advanced Materials Interfaces 9 (2022) 2200211. https://doi.org/10.1002/admi.202200211.

S. Oh, D.-Y. Kim. Characterization, antioxidant activities, and functional properties of mucilage extracted from corchorus olitorius L. Polymers 14 (2022) 2488. https://doi.org/10.3390/polym14122488.

Z. Fatima, S. Fatima, G. Muhammad, M.A. Hussain, M.A. Raza, M. Amin, A. Majeed. Stimuli-responsive glucuronoxylan polysaccharide from quince seeds for biomedical, food packaging, and environmental applications. International Journal of Biological Macromolecules (2024) 133016. https://doi.org/10.1016/j.ijbiomac.2024.133016.

E. Alpizar-Reyes, A. Román-Guerrero, S. Cortés-Camargo, S. Karina Velázquez-Gutiérrez, C. Pérez-Alonso. Recent approaches in alginate-based carriers for delivery of therapeutics and biomedicine. (2022). https://doi.org/10.1039/9781839166235-00027.

R.K. Kankala, Y.S. Zhang, S.B. Wang, C.H. Lee, A.Z. Chen. Supercritical fluid technology: an emphasis on drug delivery and related biomedical applications. Advanced healthcare materials 6 (2017) 1700433. https://doi.org/10.1002/smll.201901397.

E.D. Freitas, V.M. Freitas, P.C. Rosa, M.G. da Silva, M.G. Vieira. Development and evaluation of naproxen-loaded sericin/alginate beads for delayed and extended drug release using different covalent crosslinking agents. Materials Science and Engineering: C 118 (2021) 111412. https://doi.org/10.1016/j.molliq.2023.122040.

N. Rasheed, A.S. Mohammad, H. Hafeez, S. Farheen. Simultaneous Formulation, Evaluation and estimation of controlled release of NSAID Drug. Asian Journal of Pharmaceutical Analysis 7 (2017) 176-184. https://doi.org/10.5958/2231-5675.2017.00028.X.

W. Qin, Y. He, Z. Guo, L. Zhang, L. Wu, X. Yin, S. Shakya, A. Maharjan, Y. Tang, W. Zhu. Optimization of taste-masking on ibuprofen microspheres with selected structure features. Asian Journal of Pharmaceutical Sciences 14 (2019) 174-182. https://doi.org/10.1016/j.ajps.2018.05.003.