Abbasi, K. et al. Editorial: Time to treat the climate and nature crisis as one indivisible global health emergency. J. Gen. Intern. Med. 39, 1283–1285 (2024).

Article  CAS  Google Scholar 

Romanello, M. et al. The 2023 report of the Lancet Countdown on health and climate change: the imperative for a health-centred response in a world facing irreversible harms. Lancet 402, 2346–2394 (2023).

Article  PubMed  PubMed Central  Google Scholar 

Zhao, Q. et al. Global, regional, and national burden of mortality associated with non-optimal ambient temperatures from 2000 to 2019: a three-stage modelling study. Lancet Planet. Health 5, e415–e425 (2021).

Article  PubMed  Google Scholar 

Ballester, J. et al. Heat-related mortality in Europe during the summer of 2022. Nat. Med. 29, 1857–1866 (2023).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Khatana, S. A. M., Werner, R. M. & Groeneveld, P. W. Association of extreme heat with all-cause mortality in the contiguous US, 2008-2017. JAMA Netw. Open 5, e2212957 (2022).

Article  PubMed  PubMed Central  Google Scholar 

Rahman, M. M. et al. The effects of coexposure to extremes of heat and particulate air pollution on mortality in California: implications for climate change. Am. J. Respir. Crit. Care Med. 206, 1117–1127 (2022).

Article  PubMed  PubMed Central  Google Scholar 

Wang, Y. et al. Have residents adapted to heat wave and cold spell in the 21st century? Evidence from 136 Chinese cities. Environ. Int. 173, 107811 (2023).

Article  PubMed  Google Scholar 

Wedler, M., Pinto, J. G. & Hochman, A. More frequent, persistent, and deadly heat waves in the 21st century over the Eastern Mediterranean. Sci. Total Environ. 870, 161883 (2023).

Article  CAS  PubMed  Google Scholar 

Lüthi, S. et al. Rapid increase in the risk of heat-related mortality. Nat. Commun. 14, 4894 (2023).

Article  PubMed  PubMed Central  Google Scholar 

Gasparrini, A. et al. Projections of temperature-related excess mortality under climate change scenarios. Lancet Planet. Health 1, e360–e367 (2017).

Article  PubMed  PubMed Central  Google Scholar 

Ngcamu, B. S. Climate change effects on vulnerable populations in the Global South: a systematic review. Nat. Hazards 118, 977–991 (2023).

Article  Google Scholar 

Matlakala, F. K., Rantho, K. M. & Mapaling, C. Vulnerability of elderly people during climate-induced disasters in sub-Saharan Africa: a scoping review. Front. Hum. Dyn. https://doi.org/10.3389/fhumd.2024.1430667 (2024).

Article  Google Scholar 

Fouillet, A. et al. Excess mortality related to the August 2003 heat wave in France. Int. Arch. Occup. Environ. Health 80, 16–24 (2006).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Office for National Statistics & UK Health Security Agency. Excess Mortality During Heat-Periods: 1 June to 31 August 2022 (ONS, 2023).

Owolabi, M. O. et al. Global synergistic actions to improve brain health for human development. Nat. Rev. Neurol. 19, 371–383 (2023).

Article  PubMed  PubMed Central  Google Scholar 

Louis, S. et al. Impacts of climate change and air pollution on neurologic health, disease, and practice: a scoping review. Neurology 100, 474–483 (2023).

Article  PubMed  PubMed Central  Google Scholar 

Sisodiya, S. M. Hot brain: practical climate change advice for neurologists. Pract. Neurol. 24, 28–36 (2024).

Article  PubMed  Google Scholar 

World Health Organization. Intersectoral Global Action Plan on Epilepsy and Other Neurological Disorders 2022–2031 (WHO, 2021).

Rost, N. S. et al. Cognitive impairment and dementia after stroke: design and rationale for the DISCOVERY study. Stroke 52, e499–e516 (2021).

Article  PubMed  PubMed Central  Google Scholar 

Wolff, B., Magiati, I., Roberts, R., Pellicano, E. & Glasson, E. J. Risk and resilience factors impacting the mental health and wellbeing of siblings of individuals with neurodevelopmental conditions: a mixed methods systematic review. Clin. Psychol. Rev. 98, 102217 (2022).

Article  PubMed  Google Scholar 

Tenison, E. & Henderson, E. J. Multimorbidity and frailty: tackling complexity in Parkinson’s disease. J. Parkinsons Dis. 10, S85–S91 (2020).

Article  PubMed  PubMed Central  Google Scholar 

Weil, Z. M. & Karelina, K. Lifelong consequences of brain injuries during development: from risk to resilience. Front. Neuroendocrinol. 55, 100793 (2019).

Article  PubMed  PubMed Central  Google Scholar 

Sisodiya, S. M. et al. Climate change and disorders of the nervous system. Lancet Neurol. 23, 636–648 (2024).

Article  PubMed  Google Scholar 

Amiri, M. et al. Global warming and neurological practice: systematic review. PeerJ 9, e11941 (2021).

Article  PubMed  PubMed Central  Google Scholar 

Coulson, R. L., Mourrain, P. & Wang, G. X. Sleep deficiency as a driver of cellular stress and damage in neurological disorders. Sleep Med. Rev. 63, 101616 (2022).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Krause, A. J. et al. The sleep-deprived human brain. Nat. Rev. Neurosci. 18, 404–418 (2017).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tang, L. S., Taylor, A. L., Rinberg, A. & Marder, E. Robustness of a rhythmic circuit to short- and long-term temperature changes. J. Neurosci. 32, 10075–10085 (2012).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Alonso, L. M. & Marder, E. Temperature compensation in a small rhythmic circuit. eLife 9, e55470 (2020).

Article  PubMed  PubMed Central  Google Scholar 

Tipton, M. J., Mekjavic, I. B. & Golden, F. St. in Bove and Davis’ Diving Medicine 4th edn (eds Bove, A. A. & Davis, J. C.) Ch. 13, 261–274 (2003).

Gauer, R. & Meyers, B. K. Heat-related illnesses. Am. Fam. Physician 99, 482–489 (2019).

PubMed  Google Scholar 

Morrison, S. F. & Nakamura, K. Central neural pathways for thermoregulation. Front. Biosci. 16, 74–104 (2011).

Article  CAS  PubMed Central  Google Scholar 

Petrou, G. et al. Home energy efficiency under net zero: time to monitor UK indoor air. BMJ 377, e069435 (2022).

Article  PubMed  Google Scholar 

UK Health Security Agency. Health Effects of Climate Change (HECC) in the UK: 2023 Report. Ch. 5 (UKHSA, 2023).

Walsh, S., Merrick, R. & Brayne, C. The relevance of social and commercial determinants for neurological health. Lancet Neurol. 21, 1151–1160 (2022).

Article  PubMed  Google Scholar 

Krewski, D. et al. Determinants of neurological disease: synthesis of systematic reviews. Neurotoxicology 61, 266–289 (2017).

Article  PubMed  Google Scholar 

Lund, C. et al. Social determinants of mental disorders and the Sustainable Development Goals: a systematic review of reviews. Lancet Psychiatry 5, 357–369 (2018).

Article  PubMed  Google Scholar 

Clayton, S. Climate anxiety: psychological responses to climate change. J. Anxiety Disord. 74, 102263 (2020).

Article  PubMed  Google Scholar