Acromegaly presented with acne vulgaris: a retrospective study with 123 cases

Collier CN, Harper JC, Cafardi JA, Cantrell WC, Wang W, Foster KW et al (2008) The prevalence of acne in adults 20 years and older. J Am Acad Dermatol 58(1):56–59

Article  PubMed  Google Scholar 

Yu Y, Weng W, Li J, Zhang M, Gao Y (2021) Progress in the post-adolescent acne. Chin J Aesthetic Med. 30(05):177–180

Google Scholar 

Till AE, Goulden V, Cunliffe WJ, Holland KT (2000) The cutaneous microflora of adolescent, persistent and late-onset acne patients does not differ. Br J Dermatol 142(5):885–892

Article  PubMed  CAS  Google Scholar 

Goulden V, Clark SM, Cunliffe WJ (1997) Post-adolescent acne: a review of clinical features. Br J Dermatol 136(1):66–70

Article  PubMed  CAS  Google Scholar 

Branisteanu DE, Toader MP, Porumb EA, Serban IL, Pinzariu AC, Branisteanu CI et al (2022) Adult female acne: clinical and therapeutic particularities (Review). Exp Ther Med 23(2):151

Article  PubMed  Google Scholar 

Briganti S, Flori E, Mastrofrancesco A, Ottaviani M (2020) Acne as an altered dermato-endocrine response problem. Exp Dermatol 29(9):833–839

Article  PubMed  CAS  Google Scholar 

Lolis MS, Bowe WP, Shalita AR (2009) Acne and systemic disease. Med Clin North Am 93(6):1161–1181

Article  PubMed  CAS  Google Scholar 

Fleseriu M, Langlois F, Lim DST, Varlamov EV, Melmed S (2022) Acromegaly: pathogenesis, diagnosis, and management. Lancet Diabetes Endocrinol 10(11):804–826

Article  PubMed  CAS  Google Scholar 

Molitch ME (1992) Clinical manifestations of acromegaly. Endocrinol Metab Clin North Am 21(3):597–614

Article  PubMed  CAS  Google Scholar 

Ershadinia N, Tritos NA (2022) Diagnosis and treatment of acromegaly: an update. Mayo Clin Proc 97(2):333–346

Article  PubMed  CAS  Google Scholar 

Khamdan FA, Shah MA, Khamdan MA, Albasri E (2022) Acromegaly presenting with resistant acne vulgaris. Case Rep Dermatol 14(2):151–156

Article  PubMed  PubMed Central  Google Scholar 

Jain K, Jain VK, Aggarwal K, Bansal A (2008) Late onset isotretinoin resistant acne conglobata in a patient with acromegaly. Indian J Dermatol Venereol Leprol 74(2):139–141

Article  PubMed  Google Scholar 

Rizvi AA (2004) Some clues and pitfalls in the diagnosis of acromegaly. Endocr Pract 10(4):348–352

Article  PubMed  Google Scholar 

Guo X, Wang Y, Yao Y, Bao X, Duan L, Zhu H et al (2022) Sub-macroscopic skin presentation of acromegaly and effect of pituitary tumor surgery: a study using dermatoscopy and ultra-high-frequency ultrasound. Front Endocrinol (Lausanne) 13:1093942

Article  PubMed  Google Scholar 

Arora MK, Yadav A, Saini V (2011) Role of hormones in acne vulgaris. Clin Biochem 44(13):1035–1040

Article  PubMed  CAS  Google Scholar 

Raghunath RS, Venables ZC, Millington GW (2015) The menstrual cycle and the skin. Clin Exp Dermatol 40(2):111–115

Article  PubMed  CAS  Google Scholar 

Zaenglein AL, Pathy AL, Schlosser BJ, Alikhan A, Baldwin HE, Berson DS et al (2016) Guidelines of care for the management of acne vulgaris. J Am Acad Dermatol 74(5):945–73.e33

Article  PubMed  Google Scholar 

Goulden V, Stables GI, Cunliffe WJ (1999) Prevalence of facial acne in adults. J Am Acad Dermatol 41(4):577–580

PubMed  CAS  Google Scholar 

Shen Y, Wang T, Zhou C, Wang X, Ding X, Tian S et al (2012) Prevalence of acne vulgaris in Chinese adolescents and adults: a community-based study of 17,345 subjects in six cities. Acta Derm Venereol 92(1):40–44

Article  PubMed  Google Scholar 

Cara JF, Rosenfield RL, Furlanetto RW (1987) A longitudinal study of the relationship of plasma somatomedin-C concentration to the pubertal growth spurt. Arch Dis Child 141(5):562–564

CAS  Google Scholar 

Aizawa H, Niimura M (1995) Elevated serum insulin-like growth factor-1 (IGF-1) levels in women with postadolescent acne. J Dermatol 22(4):249–252

Article  PubMed  CAS  Google Scholar 

Cappel M, Mauger D, Thiboutot D (2005) Correlation between serum levels of insulin-like growth factor 1, dehydroepiandrosterone sulfate, and dihydrotestosterone and acne lesion counts in adult women. Arch Dermatol 141(3):333–338

Article  PubMed  CAS  Google Scholar 

Melnik BC, Schmitz G (2009) Role of insulin, insulin-like growth factor-1, hyperglycaemic food and milk consumption in the pathogenesis of acne vulgaris. Exp Dermatol 18(10):833–841

Article  PubMed  CAS  Google Scholar 

Kim HJ, Kobayashi M, Sasaki T, Kikuchi O, Amano K, Kitazumi T et al (2012) Overexpression of FoxO1 in the hypothalamus and pancreas causes obesity and glucose intolerance. Endocrinology 153(2):659–671

Article  PubMed  CAS  Google Scholar 

Smith TM, Cong Z, Gilliland KL, Clawson GA, Thiboutot DM (2006) Insulin-like growth factor-1 induces lipid production in human SEB-1 sebocytes via sterol response element-binding protein-1. J Invest Dermatol 126(6):1226–1232

Article  PubMed  CAS  Google Scholar 

Smith TM, Gilliland K, Clawson GA, Thiboutot D (2008) IGF-1 induces SREBP-1 expression and lipogenesis in SEB-1 sebocytes via activation of the phosphoinositide 3-kinase/Akt pathway. J Invest Dermatol 128(5):1286–1293

Article  PubMed  CAS  Google Scholar 

Mirdamadi Y, Thielitz A, Wiede A, Goihl A, Papakonstantinou E, Hartig R et al (2015) Insulin and insulin-like growth factor-1 can modulate the phosphoinositide-3-kinase/Akt/FoxO1 pathway in SZ95 sebocytes in vitro. Mol Cell Endocrinol 415:32–44

Article  PubMed  CAS  Google Scholar 

Kumari R, Thappa DM (2013) Role of insulin resistance and diet in acne. Indian J Dermatol Venereol Leprol 79(3):291–299

Article  PubMed  Google Scholar 

Webster GF (1995) Inflammation in acne vulgaris. J Am Acad Dermatol 33(2 Pt 1):247–253

Article  PubMed  CAS  Google Scholar 

Kim H, Moon SY, Sohn MY, Lee WJ (2017) Insulin-like growth factor-1 increases the expression of inflammatory biomarkers and sebum production in cultured sebocytes. Ann Dermatol 29(1):20–25

Article  PubMed  PubMed Central  CAS  Google Scholar 

Melnik B, Schmitz G (2008) FGFR2 signaling and the pathogenesis of acne. J Dtsch Dermatol Ges 6(9):721–728

Article  PubMed  Google Scholar 

Melnik BC, Vakilzadeh F, Aslanidis C, Schmitz G (2008) Unilateral segmental acneiform naevus: a model disorder towards understanding fibroblast growth factor receptor 2 function in acne? Br J Dermatol 158(6):1397–1399

Article  PubMed  CAS  Google Scholar 

Chen X, Guan J, Song Y, Chen P, Zheng H, Tang C et al (2008) IGF-I (CA) repeat polymorphisms and risk of cancer: a meta-analysis. J Hum Genet 53(3):227–238

Article  PubMed  CAS  Google Scholar 

Tasli L, Turgut S, Kacar N, Ayada C, Coban M, Akcilar R et al (2013) Insulin-like growth factor-I gene polymorphism in acne vulgaris. J Eur Acad Dermatol Venereol 27(2):254–257

Article  PubMed  CAS  Google Scholar 

Melnik BC, Schmitz G, Zouboulis CC (2009) Anti-acne agents attenuate FGFR2 signal transduction in acne. J Invest Dermatol 129(8):1868–1877

Article  PubMed  CAS  Google Scholar 

Im M, Kim SY, Sohn KC, Choi DK, Lee Y, Seo YJ et al (2012) Epigallocatechin-3-gallate suppresses IGF-I-induced lipogenesis and cytokine expression in sz95 sebocytes. J Invest Dermatol 132(12):2700–2708

Article  PubMed  CAS  Google Scholar 

Comments (0)

No login
gif