Chau CH, Steeg PS, Figg WD (2019) Antibody–drug conjugates for cancer. Lancet 394:793–804
Article CAS PubMed Google Scholar
Zhong L, Li Y, Xiong L et al (2021) Small molecules in targeted cancer therapy: advances, challenges, and future perspectives. Signal Transduct Target Ther 6:201
Article PubMed PubMed Central Google Scholar
Mitchell MJ, Billingsley MM, Haley RM, Wechsler ME, Peppas NA, Langer R (2021) Engineering precision nanoparticles for drug delivery. Nat Rev Drug Discovery 20:101–124
Article CAS PubMed Google Scholar
Sgouros G, Bodei L, McDevitt MR, Nedrow JR (2020) Radiopharmaceutical therapy in cancer: clinical advances and challenges. Nat Rev Drug Discovery 19:589–608
Article CAS PubMed Google Scholar
Loughlin KR (2020) William B. Coley: his hypothesis, his toxin, and the birth of immunotherapy. Urol Clin 47:413–417
Roberts NJ, Zhang L, Janku F et al (2014) Intratumoral injection of Clostridium novyi-NT spores induces antitumor responses. Sci Transl Med 6:249ra111
Article PubMed PubMed Central Google Scholar
Longhi G, Van Sinderen D, Ventura M, Turroni F (2020) Microbiota and cancer: the emerging beneficial role of bifidobacteria in cancer immunotherapy. Front Microbiol 11:575072
Article PubMed PubMed Central Google Scholar
Vitiello M, Evangelista M, Di Lascio N et al (2019) Antitumoral effects of attenuated Listeria monocytogenes in a genetically engineered mouse model of melanoma. Oncogene 38:3756–3762
Article CAS PubMed PubMed Central Google Scholar
Kang S-R, Jo EJ, Nguyen VH et al (2020) Imaging of tumor colonization by Escherichia coli using 18 F-FDS PET. Theranostics 10:4958
Article CAS PubMed PubMed Central Google Scholar
Nguyen VH, Kim H-S, Ha J-M, Hong Y, Choy HE, Min J-J (2010) Genetically engineered Salmonella typhimurium as an imageable therapeutic probe for cancer. Can Res 70:18–23
Lou X, Chen Z, He Z, Sun M, Sun J (2021) Bacteria-mediated synergistic cancer therapy: small microbiome has a big hope. Nano-Micro Lett 13:1–26
Zhou S, Gravekamp C, Bermudes D, Liu K (2018) Tumour-targeting bacteria engineered to fight cancer. Nat Rev Cancer 18:727–743
Article CAS PubMed PubMed Central Google Scholar
Sieow BF-L, Wun KS, Yong WP, Hwang IY, Chang MW (2021) Tweak to treat: reprograming bacteria for cancer treatment. Trends Cancer 7:447–464
Article CAS PubMed Google Scholar
Nguyen D-H, Chong A, Hong Y, Min J-J (2023) Bioengineering of bacteria for cancer immunotherapy. Nat Commun 14:3553
Article CAS PubMed PubMed Central Google Scholar
Kang S-R, Nguyen D-H, Yoo SW, Min J-J (2022) Bacteria and bacterial derivatives as delivery carriers for immunotherapy. Adv Drug Deliv Rev 181:114085
Article CAS PubMed Google Scholar
Chen W, Wang Y, Qin M et al (2018) Bacteria-driven hypoxia targeting for combined biotherapy and photothermal therapy. ACS Nano 12:5995–6005
Article CAS PubMed Google Scholar
Chien T, Harimoto T, Kepecs B et al (2022) Enhancing the tropism of bacteria via genetically programmed biosensors. Nat Biomed Eng 6:94–104
Article CAS PubMed Google Scholar
Dharanishanthi V, Orgad A, Rotem N et al (2021) Bacterial-induced pH shifts link individual cell physiology to macroscale collective behavior. Proc Natl Acad Sci 118:e2014346118
Article CAS PubMed PubMed Central Google Scholar
George SE, Hrubesch J, Breuing I et al (2019) Oxidative stress drives the selection of quorum sensing mutants in the Staphylococcus aureus population. Proc Natl Acad Sci 116:19145–19154
Article CAS PubMed PubMed Central Google Scholar
Qin Y, You S-H, Zhang Y, Venu A, Hong Y, Min J-J (2023) Genetic programming by nitric oxide-sensing gene switch system in tumor-targeting bacteria. Biosensors 13:266
Article CAS PubMed PubMed Central Google Scholar
Leventhal DS, Sokolovska A, Li N et al (2020) Immunotherapy with engineered bacteria by targeting the STING pathway for anti-tumor immunity. Nat Commun 11:2739
Article CAS PubMed PubMed Central Google Scholar
Nguyen D-H, You S-H, Vo A-TN et al (2022) Optimized doxycycline-inducible gene expression system for genetic programming of tumor-targeting bacteria. Mol Imag Biol 24:82–92
Zheng JH, Nguyen VH, Jiang S-N et al (2017) Two-step enhanced cancer immunotherapy with engineered Salmonella typhimurium secreting heterologous flagellin. Sci Transl Med 9:eaak9537
Cronin CA, Gluba W, Scrable H (2001) The lac operator-repressor system is functional in the mouse. Genes Dev 15:1506–1517
Article CAS PubMed PubMed Central Google Scholar
Jiang S-N, Park S-H, Lee HJ et al (2013) Engineering of bacteria for the visualization of targeted delivery of a cytolytic anticancer agent. Mol Ther 21:1985–1995
Article CAS PubMed PubMed Central Google Scholar
Wüst RC, Houtkooper RH, Auwerx J (2020) Confounding factors from inducible systems for spatiotemporal gene expression regulation. J Cell Biol 219 (7):e202003031
Cubillos-Ruiz A, Guo T, Sokolovska A et al (2021) Engineering living therapeutics with synthetic biology. Nat Rev Drug Discovery 20:941–960
Article CAS PubMed Google Scholar
Sedlmayer F, Aubel D, Fussenegger M (2018) Synthetic gene circuits for the detection, elimination and prevention of disease. Nat Biomed Eng 2:399–415
Article CAS PubMed Google Scholar
Ruder WC, Lu T, Collins JJ (2011) Synthetic biology moving into the clinic. Science 333:1248–1252
Article CAS PubMed Google Scholar
Lim WA (2010) Designing customized cell signalling circuits. Nat Rev Mol Cell Biol 11:393–403
Article CAS PubMed PubMed Central Google Scholar
Brophy JA, Voigt CA (2014) Principles of genetic circuit design. Nat Methods 11:508–520
Article CAS PubMed PubMed Central Google Scholar
Ham TS, Lee SK, Keasling JD, Arkin AP (2006) A tightly regulated inducible expression system utilizing the fim inversion recombination switch. Biotechnol Bioeng 94:1–4
Article CAS PubMed Google Scholar
Mohaisen MR, McCarthy AJ, Adriaenssens EM, Allison HE (2020) The site-specific recombination system of the Escherichia coli bacteriophage Φ24B. Front Microbiol 11:578056
Article PubMed PubMed Central Google Scholar
Yao S, Yuan P, Ouellette B et al (2020) RecV recombinase system for in vivo targeted optogenomic modifications of single cells or cell populations. Nat Methods 17:422–429
Article CAS PubMed PubMed Central Google Scholar
Bonnet J, Subsoontorn P, Endy D (2012) Rewritable digital data storage in live cells via engineered control of recombination directionality. Proc Natl Acad Sci 109:8884–8889
Article CAS PubMed PubMed Central Google Scholar
Schwan WR (2011) Regulation of fim genes in uropathogenic Escherichia coli. World J Clin Infect Dis 1:17
Article PubMed PubMed Central Google Scholar
Klemm P (1986) Two regulatory fim genes, fimB and fimE, control the phase variation of type 1 fimbriae in Escherichia coli. EMBO J 5:1389–1393
Article CAS PubMed PubMed Central Google Scholar
McCusker MP, Turner EC, Dorman CJ (2008) DNA sequence heterogeneity in Fim tyrosine-integrase recombinase-binding elements and functional motif asymmetries determine the directionality of the fim genetic switch in Escherichia coli K-12. Mol Microbiol 67:171–187
Comments (0)