Co-regulation of biofilm formation and antimicrobial resistance in Acinetobacter baumannii: from mechanisms to therapeutic strategies

Davies J, Davies D (2010) Origins and evolution of antibiotic resistance. Microbiol Mol Biol Rev 74:417–433. https://doi.org/10.1128/mmbr.00016-10

Article  CAS  PubMed  PubMed Central  Google Scholar 

WHO, FAO, OIE, UNEP (2021) Antimicrobial resistance and the united nations sustainable development cooperation framework. World Health Organization, Geneva, Switzerland

Google Scholar 

Larsson DGJ, Flach C-F (2021) Antibiotic resistance in the environment. Nat Rev Microbiol 20:257–269. https://doi.org/10.1038/s41579-021-00649-x

Article  CAS  PubMed  PubMed Central  Google Scholar 

Andersson DI, Balaban NQ, Baquero F et al (2021) Antibiotic resistance: turning evolutionary principles into clinical reality. FEMS Microbiol Rev 44:171–188. https://doi.org/10.1093/femsre/fuaa001

Article  CAS  Google Scholar 

Mackenzie JS, Jeggo M (2019) The one health approach—why is it so important? Trop Med Infect Dis 4:5–8. https://doi.org/10.3390/tropicalmed4020088

Article  Google Scholar 

McCubbin KD, Anholt RM, de Jong E et al (2021) Knowledge gaps in the understanding of antimicrobial resistance in Canada. Front Public Heal 9:1–14. https://doi.org/10.3389/fpubh.2021.726484

Article  Google Scholar 

World Bank Group (2017) Drug-resistant infections: a threat to our economic future. World Bank Group, Washington, DC

Book  Google Scholar 

Lockhart JS, Buret AG, Morck DW (2020) Biofilm and biofilm control. In: McDonnel G (ed) Disinfection, Sterilization and Preservation, 6th edn. Lippincott Williams & Wilkins (LWW), Pennsylvania, USA, pp 1320–1336

Google Scholar 

Liu C, Sun D, Zhu J et al (2020) The regulation of bacterial biofilm formation by cAMP-CRP: a mini-review. Front Microbiol 11:1–7. https://doi.org/10.3389/fmicb.2020.00802

Article  CAS  Google Scholar 

Wolska KI, Grudniak AM, Rudnicka Z, Markowska K (2016) Genetic control of bacterial biofilms. J Appl Genet 57:225–238. https://doi.org/10.1007/s13353-015-0309-2

Article  CAS  PubMed  Google Scholar 

Ha D-G, O’Toole GA (2015) c-di-GMP and its effects on biofilm formation and dispersion: a Pseudomonas aeruginosa review. Microbiol Spectr 3:1–20. https://doi.org/10.1128/microbiolspec.mb-0003-2014

Article  CAS  Google Scholar 

Wong GCL, Antani JD, Lele PP et al (2021) Roadmap on emerging concepts in the physical biology of bacterial biofilms: from surface sensing to community formation. Phys Biol 18:1–49. https://doi.org/10.1088/1478-3975/abdc0e

Article  CAS  Google Scholar 

Alsan M, Klompas M (2010) Acinetobacter baumannii: an emerging and important pathogen. J Clin Outcomes Manag 17:363–369

PubMed  PubMed Central  Google Scholar 

McConnell MJ, Actis L, Pachón J (2013) Acinetobacter baumannii: human infections, factors contributing to pathogenesis and animal models. FEMS Microbiol Rev 37:130–155. https://doi.org/10.1111/j.1574-6976.2012.00344.x

Article  CAS  PubMed  Google Scholar 

Peleg AY, Seifert H, Paterson DL (2008) Acinetobacter baumannii: emergence of a successful pathogen. Clin Microbiol Rev 21:538–582. https://doi.org/10.1128/cmr.00058-07

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lai C-C, Wang C-Y, Hsueh P-R (2020) Co-infections among patients with COVID-19: the need for combination therapy with non-anti-SARS-CoV-2 agents? Ann Thorac Surg 53:505–512. https://doi.org/10.1016/j.jmii.2020.05.013

Article  CAS  Google Scholar 

Khurana S, Singh P, Sharad N et al (2021) Profile of co-infections & secondary infections in COVID-19 patients at a dedicated COVID-19 facility of a tertiary care Indian hospital: implication on antimicrobial resistance. Indian J Med Microbiol 39:147–153. https://doi.org/10.1016/j.ijmmb.2020.10.014

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sreenath K, Batra P, Vinayaraj EV et al (2021) Coinfections with other respiratory pathogens among patients with COVID-19. Microbiol Spectr 9:1–13. https://doi.org/10.1128/Spectrum.00163-21

Article  Google Scholar 

Abdollahi A, Aliramezani A, Salehi M et al (2021) Co-infection of ST2IP carbapenem-resistant Acinetobacter baumannii with SARS-CoV-2 in the patients admitted to a Tehran tertiary referral hospital. BMC Infect Dis 21:1–7. https://doi.org/10.1186/s12879-021-06642-2

Article  CAS  Google Scholar 

Apisarnthanarak A, Weber DJ (2021) Strategy to limit multidrug-resistant Acinetobacter baumannii transmission in a cohort coronavirus disease 2019 (COVID-19) critical care unit. Infect Control Hosp Epidemiol 43:1517–1518. https://doi.org/10.1017/ice.2021.289

Article  PubMed  Google Scholar 

Gottesman T, Fedorowsky R, Yerushalmi R et al (2021) An outbreak of carbapenem-resistant Acinetobacter baumannii in a COVID-19 dedicated hospital. Infect Prev Pract 3:1–5. https://doi.org/10.1016/j.infpip.2021.100113

Article  Google Scholar 

Russo A, Gavaruzzi F, Ceccarelli G et al (2022) Multidrug-resistant Acinetobacter baumannii infections in COVID-19 patients hospitalized in intensive care unit. Infection 50:83–92. https://doi.org/10.1007/s15010-021-01643-4

Article  CAS  PubMed  Google Scholar 

Rangel K, Chagas TPG, De-Simone SG (2021) Acinetobacter baumannii infections in times of COVID-19 pandemic. Pathogens 10:1–13. https://doi.org/10.3390/pathogens10081006

Article  CAS  Google Scholar 

Boral J, Genç Z, Pınarlık F et al (2022) The association between Acinetobacter baumannii infections and the COVID-19 pandemic in an intensive care unit. Sci Rep 12:1–7. https://doi.org/10.1038/s41598-022-25493-8

Article  CAS  Google Scholar 

Ceparano M, Baccolini V, Migliara G et al (2022) Acinetobacter baumannii isolates from COVID-19 patients in a hospital intensive care unit: molecular typing and risk factors. Microorganisms 10:1–13. https://doi.org/10.3390/microorganisms10040722

Article  CAS  Google Scholar 

Mumcuoğlu İ, Çağlar H, Erdem D et al (2022) Secondary bacterial infections of the respiratory tract in COVID-19 patients. J Infect Dev Ctries 16:1131–1137. https://doi.org/10.3855/jidc.16724

Article  CAS  PubMed  Google Scholar 

Pourajam S, Kalantari E, Talebzadeh H et al (2022) Secondary bacterial infection and clinical characteristics in patients with COVID-19 admitted to two intensive care units of an academic hospital in Iran during the first wave of the pandemic. Front Cell Infect Microbiol 12:1–9. https://doi.org/10.3389/fcimb.2022.784130

Article  CAS  Google Scholar 

Montrucchio G, Corcione S, Lupia T et al (2022) The burden of carbapenem-resistant Acinetobacter baumannii in ICU COVID-19 patients: a regional experience. J Clin Med 11:1–11. https://doi.org/10.3390/jcm11175208

Article  CAS  Google Scholar 

Adelman MW, Bhamidipati DR, Hernandez-Romieu AC et al (2021) Secondary bacterial pneumonias and bloodstream infections in patients hospitalized with COVID-19. Ann Am Thorac Soc 18:1584–1587. https://doi.org/10.1513/AnnalsATS.202009-1093RL

Article  PubMed  PubMed Central  Google Scholar 

Wong SC, Lam GKM, Chen JHK et al (2021) Air dispersal of multidrug-resistant Acinetobacter baumannii: implications for nosocomial transmission during the COVID-19 pandemic. J Hosp Infect 116:78–86. https://doi.org/10.1016/j.jhin.2021.08.005

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gaibani P, Viciani E, Bartoletti M et al (2021) The lower respiratory tract microbiome of critically ill patients with COVID-19. Sci Rep 11:1–11. https://doi.org/10.1038/s41598-021-89516-6

Article  CAS  Google Scholar 

Kariyawasam RM, Julien DA, Jelinski DC et al (2022) Antimicrobial resistance (AMR) in COVID-19 patients: a systematic review and meta-analysis (November 2019–June 2021). Antimicrob Resist Infect Control 11:1–18. https://doi.org/10.1186/s13756-022-01085-z

Article  Google Scholar 

Pakharukova N, Tuittila M, Paavilainen S et al (2018) Structural basis for Acinetobacter baumannii biofilm formation. Proc Natl Acad Sci U S A 115:5558–5563. https://doi.org/10.1073/pnas.1800961115

Article  CAS  PubMed  PubMed Central  Google Scholar 

Espinal P, Martí S, Vila J (2012) Effect of biofilm formation on the survival of Acinetobacter baumannii on dry surfaces. J Hosp Infect 80:56–60. https://doi.org/10.1016/j.jhin.2011.08.013

Article  CAS  PubMed  Google Scholar 

Greene C, Wu J, Rickard AH, Xi C (2016) Evaluation of the ability of Acinetobacter baumannii to form biofilms on six different biomedical relevant surfaces. Lett Appl Microbiol 63:233–239. https://doi.org/10.1111/lam.12627

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gedefie A, Demsis W, Ashagrie M et al (2021) Acinetobacter baumannii biofilm formation and its role in disease pathogenesis: a review. Infect Drug Resist 14:3711–3719. https://doi.org/10.2147/IDR.S332051

Article  PubMed  PubMed Central  Google Scholar 

Pour NK, Dusane DH, Dhakephalkar PK et al (2011) Biofilm formation by Acinetobacter baumannii strains isolated from urinary tract infection and urinary catheters. FEMS Immunol Med Microbiol 62:328–338. https://doi.org/10.1111/j.1574-695X.2011.00818.x

Article  CAS  PubMed  Google Scholar 

Dijkshoorn L, Nemec A, Seifert H (2007) An increasing threat in hospitals: multidrug-resistant Acinetobacter baumannii. Nat Rev Microbiol 5:939–951.

Comments (0)

No login
gif