Siegel RL, Miller KD, Jemal A. Cancer statistics, 2020. CA Cancer J Clin. 2020;70:7–30.

Article  PubMed  Google Scholar 

Liang F. Optimising first-line treatment for metastatic renal cell carcinoma. Lancet. 2020;395:e8.

Article  PubMed  Google Scholar 

Singh D. Current updates and future perspectives on the management of renal cell carcinoma. Life Sci. 2021;264:118632.

Article  CAS  PubMed  Google Scholar 

Barata PC, Rini BI. Treatment of renal cell carcinoma: current status and future directions. CA Cancer J Clin. 2017;67:507–24.

Article  PubMed  Google Scholar 

Li Q, Pan X, Zhu D, Deng Z, Jiang R, Wang X. Circular RNA MAT2B promotes glycolysis and malignancy of hepatocellular carcinoma through the miR-338-3p/PKM2 axis under hypoxic stress. Hepatology. 2019;70:1298–316.

Article  CAS  PubMed  Google Scholar 

Wu X, Zhou J, Zhao L, Yang Z, Yang C, Chen Y, et al. CircCYP24A1 hampered malignant phenotype of renal cancer carcinoma through modulating CMTM-4 expression via sponging miR-421. Cell Death Dis. 2022;13:190.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wu P, Mo Y, Peng M, Tang T, Zhong Y, Deng X, et al. Emerging role of tumor-related functional peptides encoded by lncRNA and circRNA. Mol Cancer. 2020;19:22.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li J, Zhang Q, Guan Y, Liao D, Jiang D, Xiong H, et al. Circular RNA circVAMP3 promotes aerobic glycolysis and proliferation by regulating LDHA in renal cell carcinoma. Cell Death Dis. 2022;13:443.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mao W, Wang K, Xu B, Zhang H, Sun S, Hu Q, et al. ciRS-7 is a prognostic biomarker and potential gene therapy target for renal cell carcinoma. Mol Cancer. 2021;20:142.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gui CP, Liao B, Luo CG, Chen YH, Tan L, Tang YM, et al. circCHST15 is a novel prognostic biomarker that promotes clear cell renal cell carcinoma cell proliferation and metastasis through the miR-125a-5p/EIF4EBP1 axis. Mol Cancer. 2021;20:169.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Huang KB, Pan YH, Shu GN, Yao HH, Liu X, Zhou M, et al. Circular RNA circSNX6 promotes sunitinib resistance in renal cell carcinoma through the miR-1184/GPCPD1/ lysophosphatidic acid axis. Cancer Lett. 2021;523:121–34.

Article  CAS  PubMed  Google Scholar 

Shen P, Yang T, Chen Q, Yuan H, Wu P, Cai B, et al. CircNEIL3 regulatory loop promotes pancreatic ductal adenocarcinoma progression via miRNA sponging and A-to-I RNA-editing. Mol Cancer. 2021;20:51.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Fan HN, Chen ZY, Chen XY, Chen M, Yi YC, Zhu JS, et al. METTL14-mediated m(6)A modification of circORC5 suppresses gastric cancer progression by regulating miR-30c-2-3p/AKT1S1 axis. Mol Cancer. 2022;21:51.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yu YZ, Lv DJ, Wang C, Song XL, Xie T, Wang T, et al. Hsa_circ_0003258 promotes prostate cancer metastasis by complexing with IGF2BP3 and sponging miR-653-5p. Mol Cancer. 2022;21:12.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yang S, Liu Y, Li MY, Ng CSH, Yang SL, Wang S, et al. FOXP3 promotes tumor growth and metastasis by activating Wnt/β-catenin signaling pathway and EMT in non-small cell lung cancer. Mol Cancer. 2017;16:124.

Article  PubMed  PubMed Central  Google Scholar 

Liu J, Ren L, Li S, Li W, Zheng X, Yang Y, et al. The biology, function, and applications of exosomes in cancer. Acta Pharm Sin B. 2021;11:2783–97.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Pan X, Huang B, Ma Q, Ren J, Liu Y, Wang C, et al. Circular RNA circ-TNPO3 inhibits clear cell renal cell carcinoma metastasis by binding to IGF2BP2 and destabilizing SERPINH1 mRNA. Clin Transl Med. 2022;12:e994.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Thiel G, Rubil S, Lesch A, Guethlein LA, Rössler OG. Transient receptor potential TRPM3 channels: pharmacology, signaling, and biological functions. Pharmacol Res. 2017;124:92–9.

Article  CAS  PubMed  Google Scholar 

Hall DP, Cost NG, Hegde S, Kellner E, Mikhaylova O, Stratton Y, et al. TRPM3 and miR-204 establish a regulatory circuit that controls oncogenic autophagy in clear cell renal cell carcinoma. Cancer Cell. 2014;26:738–53.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li W, Yang FQ, Sun CM, Huang JH, Zhang HM, Li X, et al. circPRRC2A promotes angiogenesis and metastasis through epithelial-mesenchymal transition and upregulates TRPM3 in renal cell carcinoma. Theranostics. 2020;10:4395–409.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tay Y, Rinn J, Pandolfi PP. The multilayered complexity of ceRNA crosstalk and competition. Nature. 2014;505:344–52.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Rao M, Xu S, Zhang Y, Liu Y, Luan W, Zhou J. Long non-coding RNA ZFAS1 promotes pancreatic cancer proliferation and metastasis by sponging miR-497-5p to regulate HMGA2 expression. Cell Death Dis. 2021;12:859.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang L, Guo J, Zhou J, Wang D, Kang X, Zhou LNF-. κB maintains the stemness of colon cancer cells by downregulating miR-195-5p/497-5p and upregulating MCM2. J Exp Clin Cancer Res. 2020;39:225.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wong CH, Lou UK, Fung FK, Tong JHM, Zhang CH, To KF, et al. CircRTN4 promotes pancreatic cancer progression through a novel CircRNA-miRNA-lncRNA pathway and stabilizing epithelial-mesenchymal transition protein. Mol Cancer. 2022;21:10.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Qu F, Ye J, Pan X, Wang J, Gan S, Chu C, et al. MicroRNA-497-5p down-regulation increases PD-L1 expression in clear cell renal cell carcinoma. J Drug Target. 2019;27:67–74.

Article  CAS  PubMed  Google Scholar 

Jin Y, Huang R, Xia Y, Huang C, Qiu F, Pu J, et al. Long noncoding RNA KIF9-AS1 regulates transforming growth factor-β and autophagy signaling to enhance renal cell carcinoma chemoresistance via microRNA-497-5p. DNA Cell Biol. 2020;39:1096–103.

Article  CAS  PubMed  Google Scholar 

Pastushenko I, Blanpain C. EMT transition states during tumor progression and metastasis. Trends Cell Biol. 2019;29:212–26.

Article  CAS  PubMed  Google Scholar 

Liu H, Hu G, Wang Z, Liu Q, Zhang J, Chen Y, et al. circPTCH1 promotes invasion and metastasis in renal cell carcinoma via regulating miR-485-5p/MMP14 axis. Theranostics. 2020;10:10791–807.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gong LJ, Wang XY, Yao XD, Wu X, Gu WY. CircESRP1 inhibits clear cell renal cell carcinoma progression through the CTCF-mediated positive feedback loop. Cell Death Dis. 2021;12:1081.

Article  CAS  PubMed  PubMed Central  Google Scholar