Webb PM, Jordan SJ. Global epidemiology of epithelial ovarian cancer. Nat Rev Clin Oncol. 2024;21:389–400.

Article  PubMed  Google Scholar 

Lee B, Chang SJ, Kwon BS, Son JH, Lim MC, Kim YH, et al. Clinical guidelines for ovarian cancer: the Korean Society of Gynecologic Oncology guidelines. J Gynecol Oncol. 2024;35:e43.

Article  CAS  PubMed  Google Scholar 

Wang Y, Duval AJ, Adli M, Matei D. Biology-driven therapy advances in high-grade serous ovarian cancer. J Clin Investig. 2024;134:e174013.

Konstantinopoulos PA, Matulonis UA. Clinical and translational advances in ovarian cancer therapy. Nat Cancer. 2023;4:1239–57.

Article  PubMed  Google Scholar 

Giornelli GH. Management of relapsed ovarian cancer: a review. Springerplus. 2016;5:1197.

Article  PubMed  PubMed Central  Google Scholar 

Gaitskell K, Hermon C, Barnes I, Pirie K, Floud S, Green J, et al. Ovarian cancer survival by stage, histotype, and pre-diagnostic lifestyle factors, in the prospective UK Million Women Study. Cancer Epidemiol. 2022;76:102074.

Article  PubMed  PubMed Central  Google Scholar 

Pignata S, Cecere SC, Du Bois A, Harter P, Heitz F. Treatment of recurrent ovarian cancer. Ann Oncol. 2017;28:viii51–6.

Article  CAS  PubMed  Google Scholar 

Cesur-Ergun B, Demir-Dora D. Gene therapy in cancer. J Gene Med. 2023;25:e3550.

Article  PubMed  Google Scholar 

Ling Q, Herstine JA, Bradbury A, Gray SJ. AAV-based in vivo gene therapy for neurological disorders. Nat Rev Drug Discov. 2023;22:789–806.

Article  CAS  PubMed  Google Scholar 

Li W, Sun J, Feng SL, Wang F, Miao MZ, Wu EY, et al. Intra-articular delivery of AAV vectors encoding PD-L1 attenuates joint inflammation and tissue damage in a mouse model of rheumatoid arthritis. Front Immunol. 2023;14:1116084.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bar C, Bernardes de Jesus B, Serrano R, Tejera A, Ayuso E, Jimenez V, et al. Telomerase expression confers cardioprotection in the adult mouse heart after acute myocardial infarction. Nat Commun. 2014;5:5863.

Article  CAS  PubMed  Google Scholar 

Fischer A. Gene therapy for inborn errors of immunity: past, present and future. Nat Rev Immunol. 2023;23:397–408.

Article  CAS  PubMed  Google Scholar 

Hosseinkhani H, Domb AJ, Sharifzadeh G, Nahum V. Gene therapy for regenerative medicine. Pharmaceutics. 2023;15:856.

Bulcha JT, Wang Y, Ma H, Tai PWL, Gao G. Viral vector platforms within the gene therapy landscape. Signal Transduct Target Ther. 2021;6:53.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhao Z, Anselmo AC, Mitragotri S. Viral vector-based gene therapies in the clinic. Bioeng Transl Med. 2022;7:e10258.

Article  PubMed  Google Scholar 

Wang C, Pan C, Yong H, Wang F, Bo T, Zhao Y, et al. Emerging non-viral vectors for gene delivery. J Nanobiotechnol. 2023;21:272.

Article  Google Scholar 

Bhatia SN, Chen X, Dobrovolskaia MA, Lammers T. Cancer nanomedicine. Nat Rev Cancer. 2022;22:550–6.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kim J, Eygeris Y, Ryals RC, Jozic A, Sahay G. Strategies for non-viral vectors targeting organs beyond the liver. Nat Nanotechnol. 2024;19:428–47.

Article  CAS  PubMed  Google Scholar 

Nguyen GN, Everett JK, Kafle S, Roche AM, Raymond HE, Leiby J, et al. A long-term study of AAV gene therapy in dogs with hemophilia A identifies clonal expansions of transduced liver cells. Nat Biotechnol. 2021;39:47–55.

Article  CAS  PubMed  Google Scholar 

Jadlowsky JK, Hexner EO, Marshall A, Grupp SA, Frey NV, Riley JL, et al. Long-term safety of lentiviral or gammaretroviral gene-modified T cell therapies. Nat Med. 2025;31:1134–44.

Article  CAS  PubMed  Google Scholar 

Greig JA, Martins KM, Breton C, Lamontagne RJ, Zhu Y, He Z, et al. Integrated vector genomes may contribute to long-term expression in primate liver after AAV administration. Nat Biotechnol. 2024;42:1232–42.

Article  CAS  PubMed  Google Scholar 

Taghdiri M, Mussolino C. Viral and non-viral systems to deliver gene therapeutics to clinical targets. Int J Mol Sci. 2024;25:7333.

Hadi M, Qutaiba BAO, Jabari M, Jasoor AM, Naderloo O, Yasamineh S, et al. Recent advances in various adeno-associated viruses (AAVs) as gene therapy agents in hepatocellular carcinoma. Virol J. 2024;21:17.

Article  PubMed  PubMed Central  Google Scholar 

Zolotukhin S, Vandenberghe LH. AAV capsid design: a Goldilocks challenge. Trends Mol Med. 2022;28:183–93.

Article  CAS  PubMed  Google Scholar 

Deverman BE, Pravdo PL, Simpson BP, Kumar SR, Chan KY, Banerjee A, et al. Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain. Nat Biotechnol. 2016;34:204–9.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Paulk NK, Pekrun K, Zhu E, Nygaard S, Li B, Xu J, et al. Bioengineered AAV capsids with combined high human liver transduction in vivo and unique humoral seroreactivity. Molecular Ther J Am Soc Gene Ther. 2018;26:289–303.

Article  CAS  Google Scholar 

Lisowski L, Dane AP, Chu K, Zhang Y, Cunningham SC, Wilson EM, et al. Selection and evaluation of clinically relevant AAV variants in a xenograft liver model. Nature. 2014;506:382–6.

Article  CAS  PubMed  Google Scholar 

Sayroo R, Nolasco D, Yin Z, Colon-Cortes Y, Pandya M, Ling C, et al. Development of novel AAV serotype 6 based vectors with selective tropism for human cancer cells. Gene Ther. 2016;23:18–25.

Article  CAS  PubMed  Google Scholar 

Srivastava A. AAV vectors: are they safe?. Hum Gene Ther. 2020;31:697–9.

Article  CAS  PubMed  Google Scholar 

Kaplitt MG, Leone P, Samulski RJ, Xiao X, Pfaff DW, O’Malley KL, et al. Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain. Nat Genet. 1994;8:148–54.

Article  CAS  PubMed  Google Scholar 

Bristow RE, Tomacruz RS, Armstrong DK, Trimble EL, Montz FJ. Survival effect of maximal cytoreductive surgery for advanced ovarian carcinoma during the platinum era: a meta-analysis. J Clin Oncol. 2023;41:4065–76.

Article  PubMed  Google Scholar 

Bankhead CR, Kehoe ST, Austoker J. Symptoms associated with diagnosis of ovarian cancer: a systematic review. BJOG. 2005;112:857–65.

Article  PubMed  Google Scholar 

Norquist BM, Harrell MI, Brady MF, Walsh T, Lee MK, Gulsuner S, et al. Inherited mutations in women with ovarian carcinoma. JAMA Oncol. 2016;2:482–90.

Article  PubMed  PubMed Central  Google Scholar 

Berek JS, Renz M, Kehoe S, Kumar L, Friedlander M. Cancer of the ovary, fallopian tube, and peritoneum: 2021 update. Int J Gynaecol Obstet. 2021;155:61–85.

Article  PubMed  PubMed Central  Google Scholar 

Griffiths CT, Parker LM, Fuller AF Jr. Role of cytoreductive surgical treatment in the management of advanced ovarian cancer. Cancer Treat Rep. 1979;63:235–40.

CAS  PubMed  Google Scholar