Allard D, Allard B, Gaudreau PO, Chrobak P, Stagg J (2016) CD73-adenosine: a next-generation target in immuno-oncology. Immunotherapy 8:145–163. https://doi.org/10.2217/imt.15.106
Article CAS PubMed Google Scholar
Antonioli L, Fornai M, Pellegrini C, D’Antongiovanni V, Turiello R, Morello S, Haskó G, Blandizzi C (2021) Adenosine Signaling in the Tumor Microenvironment. Adv Exp Med Biol 1270:145–167. https://doi.org/10.1007/978-3-030-47189-7_9
Article CAS PubMed Google Scholar
Azambuja JH, Schuh RS, Michels LR, Gelsleichter NE, Beckenkamp LR, Lenz GS, de Oliveira FH, Wink MR, Stefani MA, Battastini AMO, Teixeira HF, Braganhol E (2020) CD73 as a target to improve temozolomide chemotherapy effect in glioblastoma preclinical model. Cancer Chemother Pharmacol 85:1177–1182. https://doi.org/10.1007/s00280-020-04077-1
Article CAS PubMed Google Scholar
Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A (2018) Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. Cancer J Clin 68:394–424. https://doi.org/10.3322/caac.21492
Burnstock G, Di Virgilio F (2013) Purinergic signalling and cancer. Purinergic Signalling 9:491–540. https://doi.org/10.1007/s11302-013-9372-5
Article CAS PubMed PubMed Central Google Scholar
Chen S, Fan J, Zhang M, Qin L, Dominguez D, Long A, Wang G, Ma R, Li H, Zhang Y, Fang D, Sosman J, Zhang B (2019a) CD73 expression on effector T cells sustained by TGF-β facilitates tumor resistance to anti-4-1BB/CD137 therapy. Nat Commun 10:150. https://doi.org/10.1038/s41467-018-08123-8
Article CAS PubMed PubMed Central Google Scholar
Chen YP, Chan ATC, Le QT, Blanchard P, Sun Y, Ma J (2019b) Nasopharyngeal carcinoma. Lancet (London England) 394:64–80. https://doi.org/10.1016/s0140-6736(19)30956-0
Furtmann N, Bajorath J (2015) Structural and modeling studies on ecto-5’-nucleotidase aiding in inhibitor design. Mini Rev Med Chem 15:34–40. https://doi.org/10.2174/1389557515666150219112630
Article CAS PubMed Google Scholar
Gao ZW, Dong K, Zhang HZ (2014) The roles of CD73 in cancer. Biomed Res Int 2014: 460654. https://doi.org/10.1155/2014/460654
Gao ZW, Wang HP, Lin F, Wang X, Long M, Zhang HZ, Dong K (2017) CD73 promotes proliferation and migration of human cervical cancer cells independent of its enzyme activity. BMC Cancer 17:135. https://doi.org/10.1186/s12885-017-3128-5
Article CAS PubMed PubMed Central Google Scholar
Gao ZW, Liu C, Yang L, Chen HC, Yang LF, Zhang HZ, Dong K (2021) CD73 severed as a potential prognostic marker and promote Lung Cancer cells Migration via enhancing EMT progression. Front Genet 12:728200. https://doi.org/10.3389/fgene.2021.728200
Article CAS PubMed PubMed Central Google Scholar
Giraulo C, Turiello R, Orlando L, Leonardelli S, Landsberg J, Belvedere R, Rolshoven G, Muller CE, Holzel M, Morello S (2023) The CD73 is induced by TGF-beta1 triggered by nutrient deprivation and highly expressed in dedifferentiated human melanoma. Biomed Pharmacother 165:115225. https://doi.org/10.1016/j.biopha.2023.115225
Article CAS PubMed Google Scholar
Guo J, Ma J, Zhao G, Li G, Fu Y, Luo Y, Gui R (2017) Long noncoding RNA LINC0086 functions as a tumor suppressor in nasopharyngeal carcinoma by targeting miR-214. Oncol Res 25:1189–1197. https://doi.org/10.3727/096504017x14865126670075
Article PubMed PubMed Central Google Scholar
Häusler SF, Del Barrio IM, Diessner J, Stein RG, Strohschein J, Hönig A, Dietl J, Wischhusen J (2014) Anti-CD39 and anti-CD73 antibodies A1 and 7G2 improve targeted therapy in ovarian cancer by blocking adenosine-dependent immune evasion. Am J Translational Res 6:129–139
Jeong YM, Cho H, Kim TM, Kim Y, Jeon S, Bychkov A, Jung CK (2020) CD73 overexpression promotes progression and recurrence of papillary thyroid carcinoma. Cancers 12. https://doi.org/10.3390/cancers12103042
Jiang T, Xu X, Qiao M, Li X, Zhao C, Zhou F, Gao G, Wu F, Chen X, Su C, Ren S, Zhai C, Zhou C (2018) Comprehensive evaluation of NT5E/CD73 expression and its prognostic significance in distinct types of cancers. BMC Cancer 18:267. https://doi.org/10.1186/s12885-018-4073-7
Article CAS PubMed PubMed Central Google Scholar
Junker A, Renn C, Dobelmann C, Namasivayam V, Jain S, Losenkova K, Irjala H, Duca S, Balasubramanian R, Chakraborty S, Börgel F, ZimMermann H, Yegutkin GG, Müller CE, Jacobson KA (2019) Structure-activity relationship of Purine and Pyrimidine Nucleotides as Ecto-5’-Nucleotidase (CD73) inhibitors. J Med Chem 62:3677–3695. https://doi.org/10.1021/acs.jmedchem.9b00164
Article CAS PubMed PubMed Central Google Scholar
Li S, He P, Wang Z, Liang M, Liao W, Huang Y, Chi M, Liu F, Zen N, Su R, Chen S, Liu Z, Hong H (2021) RNAi-mediated knockdown of PFK1 decreases the invasive capability and metastasis of nasopharyngeal carcinoma cell line, CNE-2. Cell cycle (Georgetown, Tex. 1–12. https://doi.org/10.1080/15384101.2020.1866279
Liao XB, Mao YP, Liu LZ, Tang LL, Sun Y, Wang Y, Lin AH, Cui CY, Li L, Ma J (2008) How does magnetic resonance imaging influence staging according to AJCC staging system for nasopharyngeal carcinoma compared with computed tomography? Int J Radiat Oncol Biol Phys 72:1368–1377. https://doi.org/10.1016/j.ijrobp.2008.03.017
Lupia M, Angiolini F, Bertalot G, Freddi S, Sachsenmeier KF, Chisci E, Kutryb-Zajac B, Confalonieri S, Smolenski RT, Giovannoni R, Colombo N, Bianchi F, Cavallaro U (2018) CD73 regulates stemness and epithelial-mesenchymal transition in ovarian Cancer-initiating cells. Stem cell Reports 10:1412–1425. https://doi.org/10.1016/j.stemcr.2018.02.009
Article CAS PubMed PubMed Central Google Scholar
Ma XL, Shen MN, Hu B, Wang BL, Yang WJ, Lv LH, Wang H, Zhou Y, Jin AL, Sun YF, Zhang CY, Qiu SJ, Pan BS, Zhou J, Fan J, Yang XR, Guo W (2019) CD73 promotes hepatocellular carcinoma progression and metastasis via activating PI3K/AKT signaling by inducing Rap1-mediated membrane localization of P110β and predicts poor prognosis. J Hematol Oncol 12:37. https://doi.org/10.1186/s13045-019-0724-7
Article PubMed PubMed Central Google Scholar
Ohana G, Bar-Yehuda S, Barer F, Fishman P (2001) Differential effect of adenosine on tumor and normal cell growth: focus on the A3 adenosine receptor. J Cell Physiol 186:19–23. https://doi.org/10.1002/1097-4652(200101)186:1<19::aid-jcp1011>3.0.co;2-3
Qian CN, Mei Y, Zhang J (2017) Cancer metastasis: issues and challenges. Chin J cancer 36:38. https://doi.org/10.1186/s40880-017-0206-7
Article PubMed PubMed Central Google Scholar
Ren ZH, Lin CZ, Cao W, Yang R, Lu W, Liu ZQ, Chen YM, Yang X, Tian Z, Wang LZ, Li J, Wang X, Chen WT, Ji T, Zhang CP (2016) CD73 is associated with poor prognosis in HNSCC. Oncotarget 7:61690–61702. https://doi.org/10.18632/oncotarget.11435
Article PubMed PubMed Central Google Scholar
Sadej R, Skladanowski AC (2012) Dual, enzymatic and non-enzymatic, function of ecto-5’-nucleotidase (eN, CD73) in migration and invasion of A375 melanoma cells. Acta Biochim Pol 59:647–652
Article CAS PubMed Google Scholar
Sciarra A, Monteiro I, Ménétrier-Caux C, Caux C, Gilbert B, Halkic N, La Rosa S, Romero P, Sempoux C, de Leval L (2019) CD73 expression in normal and pathological human hepatobiliopancreatic tissues. Cancer Immunol Immunotherapy: CII 68:467–478. https://doi.org/10.1007/s00262-018-2290-1
Article CAS PubMed Google Scholar
Shi S, Li X, You B, Shan Y, Cao X, You Y (2015) High expression of FGFR4 enhances Tumor Growth and Metastasis in Nasopharyngeal Carcinoma. J Cancer 6:1245–1254. https://doi.org/10.7150/jca.12825
Article CAS PubMed PubMed Central Google Scholar
Soleimani A, Taghizadeh E, Shahsavari S, Amini Y, Rashidpour H, Azadian E, Jafari A, Parizadeh MR, Mashayekhi K, Soukhtanloo M, Jaafari MR (2019) CD73; a key ectonucleotidase in the development of breast cancer: recent advances and perspectives. J Cell Physiol 9:14622–14632. https://doi.org/10.1002/jcp.28187
Soleimani A, Farshchi HK, Mirzavi F, Zamani P, Ghaderi A, Amini Y, Khorrami S, Mashayekhi K, Jaafari MR (2020) The therapeutic potential of targeting CD73 and CD73-derived adenosine in melanoma. Biochimie 176:21–30. https://doi.org/10.1016/j.biochi.2020.06.001
Article CAS PubMed Google Scholar
Sun Y, Li WF, Chen NY, Zhang N, Hu GQ, Xie FY, Sun Y, Chen XZ, Li JG, Zhu XD, Hu CS, Xu XY, Chen YY, Hu WH, Guo L, Mo HY, Chen L, Mao YP, Sun R, Ai P et al (2016) Induction chemotherapy plus concurrent chemoradiotherapy versus concurrent chemoradiotherapy alone in locoregionally advanced nasopharyngeal carcinoma: a phase 3, multicentre, randomised controlled trial. Lancet Oncol 17:1509–1520. https://doi.org/10.1016/s1470-2045(16)30410-7
Article CAS PubMed Google Scholar
Tang Z, Kang B, Li C, Chen T, Zhang Z (2019) GEPIA2: an enhanced web server for large-scale expression profiling and interactive analysis. Nucleic Acids Res 47:W556–w560. https://doi.org/10.1093/nar/gkz430
Article CAS PubMed PubMed Central Google Scholar
Tripathi A, Lin E, Xie W, Flaifel A, Steinharter JA, Stern Gatof EN, Bouchard G, Fleischer JH, Martinez-Chanza N, Gray C, Mantia C, Thompson L, Wei XX, Giannakis M, McGregor BA, Choueiri TK, Agarwal N, McDermott DF, Signoretti S, Harshman LC (2020) Prognostic significance and immune correlates of CD73 expression in renal cell carcinoma. J Immunotherapy cancer 8. https://doi.org/10.1136/jitc-2020-001467
Xu Z, Gu C, Yao X, Guo W, Wang H, Lin T, Li F, Chen D, Wu J, Ye G, Zhao L, Hu Y, Yu J, Shi J, Li G, Liu H (2020) CD73 promotes tumor metastasis by modulating RICS/RhoA signaling and EMT in gastric cancer. Cell Death Dis 11:202. https://doi.org/10.1038/s41419-020-2403-6
Article CAS PubMed PubMed Central Google Scholar
Xue F, Wang T, Shi H, Feng H, Feng G, Wang R, Yao Y, Yuan H (2022) CD73 facilitates invadopodia formation and boosts malignancy of head and neck squamous cell carcinoma via the MAPK signaling pathway. Cancer Sci 113:2704–2715. https://doi.org/10.1111/cas.15452
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