Guo J, Huang X, Dou L et al (2022) Aging and aging-related diseases: from molecular mechanisms to interventions and treatments. Signal Transduct Target Ther 7:391. https://doi.org/10.1038/s41392-022-01251-0

Article  CAS  PubMed  PubMed Central  Google Scholar 

Batsis JA, Villareal DT (2018) Sarcopenic obesity in older adults: aetiology, epidemiology and treatment strategies. Nat Rev Endocrinol 14:513–537. https://doi.org/10.1038/s41574-018-0062-9

Article  PubMed  PubMed Central  Google Scholar 

Zamboni M, Mazzali G (2012) Obesity in the elderly: an emerging health issue. Int J Obes 36:1151–1152. https://doi.org/10.1038/ijo.2012.120

Article  CAS  Google Scholar 

Hales CM, Fryar CD, Carroll MD et al (2018) Trends in obesity and severe obesity prevalence in US youth and adults by sex and age, 2007–2008 to 2015–2016. JAMA 319:1723. https://doi.org/10.1001/jama.2018.3060

Article  PubMed  PubMed Central  Google Scholar 

Jensen GL, Friedmann JM (2002) Obesity is associated with functional decline in community-dwelling rural older persons. J Am Geriatr Soc 50:918–923. https://doi.org/10.1046/j.1532-5415.2002.50220.x

Article  PubMed  Google Scholar 

Zizza CA, Herring A, Stevens J, Popkin BM (2002) Obesity affects nursing-care facility admission among whites but not blacks. Obes Res 10:816–823. https://doi.org/10.1038/oby.2002.110

Article  PubMed  Google Scholar 

Flegal KM, Kit BK, Orpana H, Graubard BI (2013) Association of all-cause mortality with overweight and obesity using standard body mass index categories: a systematic review and meta-analysis. JAMA 309:71. https://doi.org/10.1001/jama.2012.113905

Article  CAS  PubMed  PubMed Central  Google Scholar 

Visser M (2011) Obesity, sarcopenia and their functional consequences in old age. Proc Nutr Soc 70:114–118. https://doi.org/10.1017/S0029665110003939

Article  PubMed  Google Scholar 

Donini LM, Busetto L, Bischoff SC et al (2022) Definition and diagnostic criteria for sarcopenic obesity: ESPEN and EASO consensus statement. Clin Nutr 41:990–1000. https://doi.org/10.1016/j.clnu.2021.11.014

Article  CAS  PubMed  Google Scholar 

Wannamethee SG, Atkins JL (2015) Muscle loss and obesity: the health implications of sarcopenia and sarcopenic obesity. Proc Nutr Soc 74:405–412. https://doi.org/10.1017/S002966511500169X

Article  PubMed  Google Scholar 

Batsis JA, Mackenzie TA, Lopez-Jimenez F, Bartels SJ (2015) Sarcopenia, sarcopenic obesity, and functional impairments in older adults: National Health and Nutrition Examination Surveys 1999–2004. Nutr Res 35:1031–1039. https://doi.org/10.1016/j.nutres.2015.09.003

Article  CAS  PubMed  PubMed Central  Google Scholar 

Batsis JA, Mackenzie TA, Barre LK et al (2014) Sarcopenia, sarcopenic obesity and mortality in older adults: results from the national health and nutrition examination survey III. Eur J Clin Nutr 68:1001–1007. https://doi.org/10.1038/ejcn.2014.117

Article  CAS  PubMed  Google Scholar 

Khor EQ, Lim JP, Tay L, et al (2019) Obesity definitions in sarcopenic obesity: differences in prevalence, agreement and association with muscle function. J Frailty Aging https://doi.org/10.14283/jfa.2019.28

Seo HS, Lee H, Kim S et al (2021) Paravertebral muscles as indexes of sarcopenia and sarcopenic obesity: comparison with imaging and muscle function indexes and impact on cardiovascular and metabolic disorders. Am J Roentgenol 216:1596–1606. https://doi.org/10.2214/AJR.20.22934

Article  Google Scholar 

Bahat G, Kilic C, Topcu Y et al (2020) Fat percentage cutoff values to define obesity and prevalence of sarcopenic obesity in community-dwelling older adults in Turkey. Aging Male 23:477–482. https://doi.org/10.1080/13685538.2018.1530208

Article  PubMed  Google Scholar 

Batsis JA, Barre LK, Mackenzie TA et al (2013) Variation in the prevalence of sarcopenia and sarcopenic obesity in older adults associated with different research definitions: dual-energy x -ray absorptiometry data from the national health and nutrition examination survey 1999–2004. J Am Geriatr Soc 61:974–980. https://doi.org/10.1111/jgs.12260

Article  PubMed  Google Scholar 

Donini LM, Busetto L, Bischoff SC et al (2022) Definition and diagnostic criteria for sarcopenic obesity: ESPEN and EASO consensus Statement. Obes Facts 15:321–335. https://doi.org/10.1159/000521241

Article  PubMed  PubMed Central  Google Scholar 

Batsis JA, Petersen CL, Clark MM et al (2021) Feasibility and acceptability of a technology-based, rural weight management intervention in older adults with obesity. BMC Geriatr 21:44. https://doi.org/10.1186/s12877-020-01978-x

Article  PubMed  PubMed Central  Google Scholar 

Callahan CM, Unverzagt FW, Hui SL et al (2002) Six-Item screener to identify cognitive impairment among potential subjects for clinical Research. Med Care 40:771–781. https://doi.org/10.1097/00005650-200209000-00007

Article  PubMed  Google Scholar 

Doble SE, Fisher AG (1998) The dimensionality and validity of the older americans resources and services (OARS) activities of daily living (ADL) scale. J Outcome Meas 2:4–24

CAS  PubMed  Google Scholar 

Segal-Isaacson CJ, Wylie-Rosett J, Gans KM (2004) Validation of a short dietary assessment questionnaire: the rapid eating and activity assessment for participants short version (REAP-S). Diabetes Educ 30:774–781. https://doi.org/10.1177/014572170403000512

Article  CAS  PubMed  Google Scholar 

Subar AF, Kirkpatrick SI, Mittl B et al (2012) The automated self-administered 24-hour dietary recall (ASA24): a resource for researchers, clinicians, and educators from the national cancer institute. J Acad Nutr Diet 112:1134–1137. https://doi.org/10.1016/j.jand.2012.04.016

Article  PubMed  PubMed Central  Google Scholar 

Sayers SP, Jette AM, Haley SM et al (2004) Validation of the late-life function and disability instrument: validation of LLFDI. J Am Geriatr Soc 52:1554–1559. https://doi.org/10.1111/j.1532-5415.2004.52422.x

Article  PubMed  Google Scholar 

(2002) ATS Statement: Guidelines for the Six-Minute Walk Test. Am J Respir Crit Care Med 166:111–117. https://doi.org/10.1164/ajrccm.166.1.at1102

Bosy-Westphal A, Schautz B, Later W et al (2013) What makes a BIA equation unique? Validity of eight-electrode multifrequency BIA to estimate body composition in a healthy adult population. Eur J Clin Nutr 67:S14–S21. https://doi.org/10.1038/ejcn.2012.160

Article  PubMed  Google Scholar 

Lahav Y, Goldstein N, Gepner Y (2021) Comparison of body composition assessment across body mass index categories by two multifrequency bioelectrical impedance analysis devices and dual-energy X-ray absorptiometry in clinical settings. Eur J Clin Nutr 75:1275–1282. https://doi.org/10.1038/s41430-020-00839-5

Article  PubMed  Google Scholar 

Janssen I, Heymsfield SB, Baumgartner RN (1985) Ross R (2000) Estimation of skeletal muscle mass by bioelectrical impedance analysis. J Appl Physiol Bethesda Md 89:465–471. https://doi.org/10.1152/jappl.2000.89.2.465

Article  Google Scholar 

Bhasin S, Travison TG, Manini TM et al (2020) Sarcopenia definition: the position statements of the sarcopenia definition and outcomes consortium. J Am Geriatr Soc 68:1410–1418. https://doi.org/10.1111/jgs.16372

Article  PubMed  Google Scholar 

Gortan Cappellari G, Guillet C, Poggiogalle E et al (2023) Sarcopenic obesity research perspectives outlined by the sarcopenic obesity global leadership initiative (SOGLI)—proceedings from the SOGLI consortium meeting in rome November 2022. Clin Nutr Edinb Scotl 42:687–699. https://doi.org/10.1016/j.clnu.2023.02.018

Article  Google Scholar 

Gallagher D, Heymsfield SB, Heo M et al (2000) Healthy percentage body fat ranges: an approach for developing guidelines based on body mass index. Am J Clin Nutr 72:694–701. https://doi.org/10.1093/ajcn/72.3.694

Article  CAS  PubMed  Google Scholar 

Dodds RM, Syddall HE, Cooper R, et al (2014) Grip strength across the life course: normative data from twelve British studies. PloS One 9:e113637. https://doi.org/10.1371/journal.pone.0113637

Patel SM, Duchowny KA, Kiel DP et al (2020) Sarcopenia Definition & Outcomes Consortium Defined Low Grip Strength in Two Cross-Sectional, Population-Based Cohorts. J Am Geriatr Soc 68:1438–1444. https://doi.org/10.1111/jgs.16419

Article  PubMed  Google Scholar 

Rikli RE, Jones CJ (2013) Development and validation of criterion-referenced clinically relevant fitness standards for maintaining physical independence in later years. Gerontologist 53:255–267. https://doi.org/10.1093/geront/gns071

Article  PubMed  Google Scholar 

Jensen MD, Ryan DH, Apovian CM, et al (2014) 2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults: a report of the American college of cardiology/American heart association task force on practice guidelines and the obesity society. circulation 129 https://doi.org/10.1161/01.cir.0000437739.71477.ee

Wright AA, Cook CE, Baxter GD et al (2011) A comparison of 3 methodological approaches to defining major clinically important improvement of 4 performance measures in patients with hip osteoarthritis. J Orthop Sports Phys Ther 41:319–327. https://doi.org/10.2519/jospt.2011.3515

Article  PubMed  Google Scholar 

Areta JL, Burke LM, Camera DM et al (2014) Reduced resting skeletal muscle protein synthesis is rescued by resistance exercise and protein ingestion following short-term energy deficit. Am J Physiol Endocrinol Metab 306:E989-997. https://doi.org/10.1152/ajpendo.00590.2013

Article  CAS  PubMed  Google Scholar 

Pasiakos SM, Cao JJ, Margolis LM et al (2013) Effects of high-protein diets on fat-free mass and muscle protein synthesis following weight loss: a randomized controlled trial. FASEB J Off Publ Fed Am Soc Exp Biol 27:3837–3847. https://doi.org/10.1096/fj.13-230227

Article  CAS  Google Scholar 

Zibellini J, Seimon RV, Lee CMY et al (2016) Effect of diet-induced weight loss on muscle strength in adults with overweight or obesity—a systematic review and meta-analysis of clinical trials. Obes Rev Off J Int Assoc Study Obes 17:647–663. https://doi.org/10.1111/obr.12422

Article  CAS