Primary central nervous system lymphoma

Kluin, P. M., Deckert, M. & Ferry, J. A. In WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues 300–302 (IARC, 2017).

Alaggio, R. et al. The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms. Leukemia 36, 1720–1748 (2022).

Article  PubMed  PubMed Central  Google Scholar 

Campo, E. et al. The International Consensus Classification of Mature Lymphoid Neoplasms: a report from the Clinical Advisory Committee. Blood 140, 1229–1253 (2022).

Article  CAS  PubMed  Google Scholar 

Shiels, M. S. et al. Trends in primary central nervous system lymphoma incidence and survival in the U.S. Br. J. Haematol. 174, 417–424 (2016).

Article  PubMed  PubMed Central  Google Scholar 

Ferreri, A. J. et al. Summary statement on primary central nervous system lymphomas from the Eighth International Conference on Malignant Lymphoma, Lugano, Switzerland, June 12 to 15, 2002. J. Clin. Oncol. 21, 2407–2414 (2003).

Article  PubMed  Google Scholar 

Velasco, R. et al. Diagnostic delay and outcome in immunocompetent patients with primary central nervous system lymphoma in Spain: a multicentric study. J. Neurooncol. https://doi.org/10.1007/s11060-020-03547-z (2020).

Article  PubMed  Google Scholar 

Barajas, R. F. et al. Consensus recommendations for MRI and PET imaging of primary central nervous system lymphoma: guideline statement from the International Primary CNS Lymphoma Collaborative Group (IPCG). Neuro. Oncol. 23, 1056–1071 (2021). Consensus recommendations for neuroimaging of the International PCNSL Collaborative Group.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Baraniskin, A. & Schroers, R. Liquid biopsy and other non-invasive diagnostic measures in PCNSL. Cancers 13, 2665 (2021).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Houillier, C. et al. Management and outcome of primary CNS lymphoma in the modern era: an LOC network study. Neurology 94, e1027–e1039 (2020).

Article  PubMed  PubMed Central  Google Scholar 

Dandachi, D. et al. Primary central nervous system lymphoma in patients with and without HIV infection: a multicenter study and comparison with U.S national data. Cancer Causes Control 30, 477–488 (2019).

Article  PubMed  Google Scholar 

Haldorsen, I. S. et al. Increasing incidence and continued dismal outcome of primary central nervous system lymphoma in Norway 1989–2003: time trends in a 15-year national survey. Cancer 110, 1803–1814 (2007).

Article  PubMed  Google Scholar 

Ostrom, Q. T. et al. CBTRUS Statistical Report: primary brain and other central nervous system tumors diagnosed in the United States in 2010–2014. Neuro. Oncol. 19, v1–v88 (2017).

Article  PubMed  PubMed Central  Google Scholar 

van der Meulen, M., Dinmohamed, A. G., Visser, O., Doorduijn, J. K. & Bromberg, J. E. C. Improved survival in primary central nervous system lymphoma up to age 70 only: a population-based study on incidence, primary treatment and survival in the Netherlands, 1989-2015. Leukemia 31, 1822–1825 (2017).

Article  PubMed  Google Scholar 

Eloranta, S. et al. Increasing incidence of primary central nervous system lymphoma but no improvement in survival in Sweden 2000–2013. Eur. J. Haematol. 100, 61–68 (2018).

Article  PubMed  Google Scholar 

Makino, K., Nakamura, H., Kino, T., Takeshima, H. & Kuratsu, J. Rising incidence of primary central nervous system lymphoma in Kumamoto, Japan. Surg. Neurol. 66, 503–506 (2006).

Article  PubMed  Google Scholar 

Farrall, A. L. & Smith, J. R. Changing incidence and survival of primary central nervous system lymphoma in Australia: a 33-year national population-based study. Cancers 13, 403 (2021).

Article  PubMed  PubMed Central  Google Scholar 

Puhakka, I. et al. Primary central nervous system lymphoma high incidence and poor survival in Finnish population-based analysis. BMC Cancer 22, 236 (2022).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mendez, J. S. et al. The elderly left behind-changes in survival trends of primary central nervous system lymphoma over the past 4 decades. Neuro. Oncol. 20, 687–694 (2018).

Article  PubMed  Google Scholar 

Villano, J. L., Koshy, M., Shaikh, H., Dolecek, T. A. & McCarthy, B. J. Age, gender, and racial differences in incidence and survival in primary CNS lymphoma. Br. J. Cancer 105, 1414–1418 (2011).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Attarbaschi, A. et al. Primary central nervous system lymphoma: initial features, outcome, and late effects in 75 children and adolescents. Blood Adv. 3, 4291–4297 (2019). The largest series of PCNSL in adolescents and children.

Article  PubMed  PubMed Central  Google Scholar 

Engels, E. A. et al. Trends in cancer risk among people with AIDS in the United States 1980-2002. AIDS 20, 1645–1654 (2006).

Article  PubMed  Google Scholar 

Wolf, T. et al. Changing incidence and prognostic factors of survival in AIDS-related non-Hodgkin’s lymphoma in the era of highly active antiretroviral therapy (HAART). Leuk. Lymphoma 46, 207–215 (2005).

Article  PubMed  Google Scholar 

Franca, R. A. et al. HIV prevalence in primary central nervous system lymphoma: a systematic review and meta-analysis. Pathol. Res. Pract. 216, 153192 (2020).

Article  PubMed  Google Scholar 

Mahale, P., Shiels, M. S., Lynch, C. F. & Engels, E. A. Incidence and outcomes of primary central nervous system lymphoma in solid organ transplant recipients. Am. J. Transplant. 18, 453–461 (2018).

Article  CAS  PubMed  Google Scholar 

Schiff, D., Suman, V. J., Yang, P., Rocca, W. A. & O’Neill, B. P. Risk factors for primary central nervous system lymphoma: a case-control study. Cancer 82, 975–982 (1998).

Article  CAS  PubMed  Google Scholar 

Montesinos-Rongen, M. et al. Primary central nervous system lymphomas are derived from germinal-center B cells and show a preferential usage of the V4-34 gene segment. Am. J. Pathol. 155, 2077–2086 (1999).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Vater, I. et al. The mutational pattern of primary lymphoma of the central nervous system determined by whole-exome sequencing. Leukemia 29, 677–685 (2015).

Article  CAS  PubMed  Google Scholar 

Montesinos-Rongen, M. et al. Primary central nervous system (CNS) lymphoma B cell receptors recognize CNS proteins. J. Immunol. 195, 1312–1319 (2015).

Article  CAS  PubMed  Google Scholar 

Montesinos-Rongen, M., Purschke, F., Küppers, R. & Deckert, M. Immunoglobulin repertoire of primary lymphomas of the central nervous system. J. Neuropathol. Exp. Neurol. 73, 1116–1125 (2014).

Article  CAS  PubMed  Google Scholar 

Thurner, L. et al. Hyper-N-glycosylated SAMD14 and neurabin-I as driver autoantigens of primary central nervous system lymphoma. Blood 132, 2744–2753 (2018).

Article  CAS  PubMed  Google Scholar 

Hernandez-Verdin, I. et al. Molecular and clinical diversity in primary central nervous system lymphoma. Ann. Oncol. 34, 186–199 (2022).

Article  PubMed  Google Scholar 

Montesinos-Rongen, M., Van Roost, D., Schaller, C., Wiestler, O. D. & Deckert, M. Primary diffuse large B-cell lymphomas of the central nervous system are targeted by aberrant somatic hypermutation. Blood 103, 1869–1875 (2004).

Article  CAS  PubMed  Google Scholar 

Fukumura, K. et al. Genomic characterization of primary central nervous system lymphoma. Acta Neuropathol. 131, 865–875 (2016).

Article  CAS  PubMed  Google Scholar 

Tateishi, K. et al. A hyperactive RelA/p65-hexokinase 2 signaling axis drives primary central nervous system lymphoma. Cancer Res. 80, 5330–5343 (2020).

Article  PubMed  Google Scholar 

Alizadeh, A. A. et al. Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 403, 503–511 (2000).

Article  CAS  PubMed  Google Scholar 

Chapuy, B. et al. Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes. Nat. Med. 24, 679–690 (2018).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wright, G. W. et al. A probabilistic classification tool for genetic subtypes of diffuse large B cell lymphoma with therapeutic implications. Cancer Cell. 37, 551–568.e14 (2020).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chapuy, B. et al. Targetable genetic features of primary testicular and primary central nervous system lymphomas. Blood 127, 869–881 (2016).

Article  CAS  PubMed  PubMed Central 

Comments (0)

No login
gif