Intramucosal Dexamethasone versus Photobiomodulation After Impacted Mandibular Third Molar Surgery: A Split-Mouth Randomized Controlled Study

Balakrishnan G, Narendar R, Kavin T, Venkataraman S, Gokulanathan S (2017) Incidence of trismus in transalveolar extraction of lower third molar. J Pharm Bioall Sci 9:S222–S227

Article  Google Scholar 

Kaleem BR (2019) Influence of tooth sectioning on postoperative pain, swelling and trismus following surgical removal of impacted mandibular third molar. J Dent Res Prac 1(1):11–17

Google Scholar 

He WL, Yu FY, Li CJ, Pan J, Zhuang R, Duan PJ (2015) A systematic review and meta-analysis on the efficacy of low-level laser therapy in the management of complication after mandibular third molar surgery. Lasers Med Sci 30(6):1779–1788

Article  CAS  PubMed  Google Scholar 

Nourwali I (2021) The effects of platelet-rich fibrin on post-surgical complications following removal of impacted wisdom teeth: a pilot study. J Taibah Univ Med Sci 16(4):521–528

PubMed  PubMed Central  Google Scholar 

Glória JCR, Douglas-de-Oliveira DW, Silva E, Falci LDA, Dos Santos SGM (2020) Influence of ozonized water on pain, oedema, and trismus during impacted third molar surgery: a randomized, triple blind clinical trial. BMC Oral Health 20(1):41

Article  PubMed  PubMed Central  Google Scholar 

Shivhare P, Shankarnarayan L, Singh A, Patil ST, Yadav M (2015) Role of immunomodulators in oral diseases. Int J Oral Health Med Res 2(3):73–80

Google Scholar 

Moraschini V, Hidalgo R, Porto B (eds) (2016) Effect of submucosal injection of dexamethasone after third molar surgery: a meta-analysis of randomized controlled trials. Int J Oral Maxillofac Surg. ;45(2):232 – 40

Majid OW, Mahmood WK (2011) Effect of submucosal and intramuscular dexamethasone on postoperative sequelae after third molar surgery: comparative study. Br J Oral Maxillofac Surg 49(8):647–652

Article  PubMed  Google Scholar 

Lau AAL, De Silva RK, Thomson M, De Silva H, Tong D (2021) Third molar surgery outcomes: a randomized clinical trial comparing submucosal and intravenous dexamethasone. J Oral Maxillofac Surg 79(2):295–304

Article  PubMed  Google Scholar 

Eltahir L, Elgendy M, Ali G, Elamin A, Omer S, Khazam N (2025) Photobiomodulation in dentistry: mechanisms, clinical applications and evidence-based guidelines. Bioinformation 21(11):4203–4206

Article  PubMed  PubMed Central  Google Scholar 

Collado-Murcia Y, Parra-Perez F, López-Jornet P (2026) Effect of immediate photobiomodulation on pain and inflammation after oral biopsy: a randomized clinical study. Clin Oral Investig 30(3):92

Article  PubMed  PubMed Central  Google Scholar 

Pergolini D, Del Vecchio A, Palaia G, Rocchetti F, Cefalà R, De Angelis R, Tenore G, Romeo U (2022) Photobiomodulation after surgical extraction of the lower third molars: a narrative review. Oral 2(1):18–28

Article  Google Scholar 

General Assembly of the World Medical Association (2014) World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects. J Am Coll Dent 81(3):14–18

Google Scholar 

Antunes AA, Avelar RL, Martins Neto EC, Frota R, Dias E (2011) Effect of two routes of administration of dexamethasone on pain, edema, and trismus in impacted lower third molar surgery. Oral maxillofacial Surg 15(4):217–223

Article  Google Scholar 

Momeni E, Kazemi F, Sanaei-Rad P (2022) Extraoral low-level laser therapy can decrease pain but not edema and trismus after surgical extraction of impacted mandibular third molars: a randomized, placebo-controlled clinical trial. BMC Oral Health 22(1):1–8

Article  Google Scholar 

Shivhare P, Haidry N, Sah N, Kumar A, Gupta A et al (2022) Comparative evaluation of efficacy and safety of the diode laser (980 nm) and sclerotherapy in the treatment of oral vascular malformations. Int J Vasc Med 2022:2785859

PubMed  PubMed Central  Google Scholar 

Momesso GAC, Grossi-Oliveira GA, Silva WPP, Akira R, Chiba F, Polo TOB (2021) A triple-blind randomized clinical trial of different associations between dexamethasone and non-steroids anti-inflammatories for preemptive action in third molar extractions. Sci Rep 11(1):24445

Article  CAS  PubMed  PubMed Central  Google Scholar 

Shivhare P, Parihar A (2021) Case history. In: Shivhare P, Parihar A (eds) Textbook of oral medicine and radiology, 2nd edn. Paras, Hyderabad, pp 27–150

Google Scholar 

Hadad H, Santos AFP, de Jesus LK, Poli PP, Mariano RC, Theodoro LH, Maiorana C, Souza FÁ (2022) Photobiomodulation therapy improves postoperative pain and edema in third molar surgeries: a randomized, comparative, double-blind, and prospective clinical trial. J Oral Maxillofac Surg. ; 80(1):37.e1-37.e12

Momeni E, Barati H, Arbabi MR, Jalali B, Moosavi MS (2021) Low-level laser therapy using laser diode 940 nm in the mandibular impacted third molar surgery: double-blind randomized clinical trial. BMC Oral Health 21(1):77

Article  CAS  PubMed  PubMed Central  Google Scholar 

Singh V, Garg A, Bhagol A, Savarna S, Agarwal SK (2019) Photobiomodulation alleviates postoperative discomfort after mandibular third molar surgery. J Oral Maxillofac Surg 77(12):2412–2421

Article  PubMed  Google Scholar 

Kahraman SA, Cetiner S, Strauss RA (2017) The effects of transcutaneous and intraoral low-level laser therapy after extraction of lower third molars: a randomized single blind, placebo controlled dual-center study. Photomed Laser Surg 35(8):401–407

Article  CAS  PubMed  Google Scholar 

Aras MH, Güngörmüş M (2010) Placebo-controlled randomized clinical trial of the effect two different low-level laser therapies (LLLT)--intraoral and extraoral–on trismus and facial swelling following surgical extraction of the lower third molar. Lasers Med Sci 25(5):641–645

Article  PubMed  Google Scholar 

Bianchi de Moraes M, Gomes de Oliveira R, Raldi FV, Nascimento RD, Santamaria MP, Loureiro Sato FR (2020) Does the low-intensity laser protocol affect tissue healing after third molar removal? J Oral Maxillofac Surg 78(11):1920e1–1920e9

Article  Google Scholar 

Kohli A, Anehosur V, Radder K (2023) Comparative study of the efficacy of low-level laser therapy and dexamethasone in reducing the severity of post-operative inflammatory response following surgical extraction of mandibular third molars. J Maxillofac Oral Surg 22(1):165–171

Article  PubMed  Google Scholar 

Comments (0)

No login
gif