Abdel-Hay N, Kabirova M, Yaka R (2024) A discrete subpopulation of PFC-LHb neurons govern cocaine place preference. Transl Psychiatry 14(1):269. https://doi.org/10.1038/s41398-024-02988-8

Article  PubMed  PubMed Central  CAS  Google Scholar 

Ährlund-Richter S, Xuan Y, van Lunteren JA, Kim H, Ortiz C, Pollak Dorocic I, Meletis K et al (2019) A whole-brain atlas of monosynaptic input targeting four different cell types in the medial prefrontal cortex of the mouse. Nat Neurosci 22(4):657–668. https://doi.org/10.1038/s41593-019-0354-y

Article  PubMed  CAS  Google Scholar 

Algaidi SA (2025) Chronic stress-induced neuroplasticity in the prefrontal cortex: structural, functional, and molecular mechanisms from development to aging. Brain Res 1851:149461. https://doi.org/10.1016/j.brainres.2025.149461

Article  PubMed  CAS  Google Scholar 

Anastasiades PG, Marlin JJ, Carter AG (2018) Cell-type specificity of callosally evoked excitation and feedforward inhibition in the prefrontal cortex. Cell Rep 22(3):679–692. https://doi.org/10.1016/j.celrep.2017.12.073

Article  PubMed  PubMed Central  CAS  Google Scholar 

Anastasiades PG, Collins DP, Carter AG (2021) Mediodorsal and ventromedial thalamus engage distinct L1 circuits in the prefrontal cortex. Neuron 109(2):314-330.e314. https://doi.org/10.1016/j.neuron.2020.10.031

Article  PubMed  CAS  Google Scholar 

Andersen JV, Markussen KH, Jakobsen E, Schousboe A, Waagepetersen HS, Rosenberg PA, Aldana BI (2021) Glutamate metabolism and recycling at the excitatory synapse in health and neurodegeneration. Neuropharmacology 196:108719. https://doi.org/10.1016/j.neuropharm.2021.108719

Article  PubMed  CAS  Google Scholar 

Arruda-Carvalho M, Clem RL (2014) Pathway-selective adjustment of prefrontal-amygdala transmission during fear encoding. J Neurosci 34(47):15601–15609. https://doi.org/10.1523/jneurosci.2664-14.2014

Article  PubMed  PubMed Central  Google Scholar 

Baker DA, McFarland K, Lake RW, Shen H, Tang XC, Toda S, Kalivas PW (2003) Neuroadaptations in cystine-glutamate exchange underlie cocaine relapse. Nat Neurosci 6(7):743–749. https://doi.org/10.1038/nn1069

Article  PubMed  CAS  Google Scholar 

Baker A, Kalmbach B, Morishima M, Kim J, Juavinett A, Li N, Dembrow N (2018) Specialized subpopulations of deep-layer pyramidal neurons in the neocortex: bridging cellular properties to functional consequences. J Neurosci 38(24):5441–5455. https://doi.org/10.1523/jneurosci.0150-18.2018

Article  PubMed  PubMed Central  CAS  Google Scholar 

Berlin GS, Hollander E (2014) Compulsivity, impulsivity, and the DSM-5 process. CNS Spectr 19(1):62–68. https://doi.org/10.1017/s1092852913000722

Article  PubMed  Google Scholar 

Berton O, McClung CA, Dileone RJ, Krishnan V, Renthal W, Russo SJ, Graham D et al (2006) Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress. Science 311(5762):864–868. https://doi.org/10.1126/science.1120972

Article  PubMed  CAS  Google Scholar 

Birdsong WT, Jongbloets BC, Engeln KA, Wang D, Scherrer G, Mao T (2019) Synapse-specific opioid modulation of thalamo-cortico-striatal circuits. Elife. https://doi.org/10.7554/eLife.45146

Article  PubMed  PubMed Central  Google Scholar 

Blacktop JM, Sorg BA (2019) Perineuronal nets in the lateral hypothalamus area regulate cue-induced reinstatement of cocaine-seeking behavior. Neuropsychopharmacology 44(5):850–858. https://doi.org/10.1038/s41386-018-0212-8

Article  PubMed  CAS  Google Scholar 

Bloodgood DW, Sugam JA, Holmes A, Kash TL (2018) Fear extinction requires infralimbic cortex projections to the basolateral amygdala. Transl Psychiatry 8(1):60. https://doi.org/10.1038/s41398-018-0106-x

Article  PubMed  PubMed Central  Google Scholar 

Borkar CD, Stelly CE, Fu X, Dorofeikova M, Le QE, Vutukuri R, Vo C et al (2024) Top-down control of flight by a non-canonical cortico-amygdala pathway. Nature 625(7996):743–749. https://doi.org/10.1038/s41586-023-06912-w

Article  PubMed  PubMed Central  CAS  Google Scholar 

Bossert JM, Stern AL, Theberge FR, Cifani C, Koya E, Hope BT, Shaham Y (2011) Ventral medial prefrontal cortex neuronal ensembles mediate context-induced relapse to heroin. Nat Neurosci 14(4):420–422. https://doi.org/10.1038/nn.2758

Article  PubMed  PubMed Central  CAS  Google Scholar 

Brodmann K (1985) Vergleichende lokalisationslehre der Grosshirnrinde in ihren prinzipien dargestellt auf Grund des zellenbaues (Barth, 1909), pp 15–22. https://jstor.org/stable/community.24783456

Burgos-Robles A, Kimchi EY, Izadmehr EM, Porzenheim MJ, Ramos-Guasp WA, Nieh EH, Felix-Ortiz AC et al (2017) Amygdala inputs to prefrontal cortex guide behavior amid conflicting cues of reward and punishment. Nat Neurosci 20(6):824–835. https://doi.org/10.1038/nn.4553

Article  PubMed  PubMed Central  CAS  Google Scholar 

Carlén M (2017) What constitutes the prefrontal cortex? Science 358(6362):478–482. https://doi.org/10.1126/science.aan8868

Article  PubMed  CAS  Google Scholar 

Cavallaro J, Yeisley J, Akdoǧan B, Salazar RE, Floeder JR, Balsam PD, Gallo EF (2023) Dopamine D2 receptors in nucleus accumbens cholinergic interneurons increase impulsive choice. Neuropsychopharmacology 48(9):1309–1317. https://doi.org/10.1038/s41386-023-01608-1

Article  PubMed  PubMed Central  CAS  Google Scholar 

Ceceli AO, Bradberry CW, Goldstein RZ (2022) The neurobiology of drug addiction: cross-species insights into the dysfunction and recovery of the prefrontal cortex. Neuropsychopharmacology 47(1):276–291. https://doi.org/10.1038/s41386-021-01153-9

Article  PubMed  Google Scholar 

Chen BT, Yau HJ, Hatch C, Kusumoto-Yoshida I, Cho SL, Hopf FW, Bonci A (2013) Rescuing cocaine-induced prefrontal cortex hypoactivity prevents compulsive cocaine seeking. Nature 496(7445):359–362. https://doi.org/10.1038/nature12024

Article  PubMed  CAS  Google Scholar 

Chen J, Dong B, Feng X, Jiang D, Chen G, Long C, Yang L (2020) Aberrant mPFC GABAergic synaptic transmission and fear behavior in neuroligin-2 R215H knock-in mice. Brain Res 1730:146671. https://doi.org/10.1016/j.brainres.2020.146671

Article  PubMed  CAS  Google Scholar 

Cho JH, Deisseroth K, Bolshakov VY (2013) Synaptic encoding of fear extinction in mPFC-amygdala circuits. Neuron 80(6):1491–1507. https://doi.org/10.1016/j.neuron.2013.09.025

Article  PubMed  CAS  Google Scholar 

Collins DP, Anastasiades PG, Marlin JJ, Carter AG (2018) Reciprocal circuits linking the prefrontal cortex with dorsal and ventral thalamic nuclei. Neuron 98(2):366-379.e364. https://doi.org/10.1016/j.neuron.2018.03.024

Article  PubMed  PubMed Central  CAS  Google Scholar 

Collins SA, Stinson HE, Himes A, Nestor-Kalinoski A, Ninan I (2023) Sex-specific modulation of the medial prefrontal cortex by glutamatergic median raphe neurons. Sci Adv 9(45):eadg4800. https://doi.org/10.1126/sciadv.adg4800

Article  PubMed  PubMed Central  CAS  Google Scholar 

Cooper S, Robison AJ, Mazei-Robison MS (2017) Reward circuitry in addiction. Neurotherapeutics 14(3):687–697. https://doi.org/10.1007/s13311-017-0525-z

Article  PubMed  PubMed Central  CAS  Google Scholar 

D’Cunha TM, Daoud E, Rizzo D, Bishop AB, Russo M, Mourra G, Hamel L et al (2017) Augmentation of heroin seeking following chronic food restriction in the rat: differential role for dopamine transmission in the nucleus accumbens shell and core. Neuropsychopharmacology 42(5):1136–1145. https://doi.org/10.1038/npp.2016.250