Multisensory coding of self-motion and its contribution to navigation

Campbell, M. G. & Giocomo, L. M. Self-motion processing in visual and entorhinal cortices: inputs, integration, and implications for position coding. J. Neurophysiol. 120, 2091–2106 (2018).

Article  PubMed  PubMed Central  Google Scholar 

Mittelstaedt, M. L. & Mittelstaedt, H. Homing by path integration in a mammal. Naturwissenschaften 67, 566–567 (1980).

Article  Google Scholar 

Senkowski, D. & Engel, A. K. Multi-timescale neural dynamics for multisensory integration. Nat. Rev. Neurosci. 25, 625–642 (2024).

Article  CAS  PubMed  Google Scholar 

Stein, B. E. M, M. A. Multisensory Integration: The Merging of the Senses (MIT Press, 1993).

Parise, C. V. & Ernst, M. O. Correlation detection as a general mechanism for multisensory integration. Nat. Commun. 7, 11543 (2016).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Whittington, J. C. R., McCaffary, D., Bakermans, J. J. W. & Behrens, T. E. J. How to build a cognitive map. Nat. Neurosci. 25, 1257–1272 (2022).

Article  CAS  PubMed  Google Scholar 

Grabherr, L., Nicoucar, K., Mast, F. W. & Merfeld, D. M. Vestibular thresholds for yaw rotation about an Earth-vertical axis as a function of frequency. Exp. Brain Res. 186, 677–681 (2008).

Article  PubMed  Google Scholar 

MacNeilage, P. R., Turner, A. H. & Angelaki, D. E. Canal–otolith interactions and detection thresholds of linear and angular components during curved-path self-motion. J. Neurophysiol. 104, 765–773 (2010).

Article  PubMed  PubMed Central  Google Scholar 

Valko, Y., Lewis, R. F., Priesol, A. J. & Merfeld, D. M. Vestibular labyrinth contributions to human whole-body motion discrimination. J. Neurosci. 32, 13537–13542 (2012).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gu, Y., DeAngelis, G. C. & Angelaki, D. E. A functional link between area MSTd and heading perception based on vestibular signals. Nat. Neurosci. 10, 1038–1047 (2007).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu, S., Dickman, J. D., Newlands, S. D., DeAngelis, G. C. & Angelaki, D. E. Reduced choice-related activity and correlated noise accompany perceptual deficits following unilateral vestibular lesion. Proc. Natl Acad. Sci. USA 110, 17999–18004 (2013).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cullen, K. E. & Taube, J. S. Our sense of direction: progress, controversies and challenges. Nat. Neurosci. 20, 1465–1473 (2017).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu, S., Gu, Y., DeAngelis, G. C. & Angelaki, D. E. Choice-related activity and correlated noise in subcortical vestibular neurons. Nat. Neurosci. 16, 89–97 (2013).

Article  PubMed  Google Scholar 

Liu, S., Yakusheva, T., Deangelis, G. C. & Angelaki, D. E. Direction discrimination thresholds of vestibular and cerebellar nuclei neurons. J. Neurosci. 30, 439–448 (2010).

Article  PubMed  PubMed Central  Google Scholar 

Yakusheva, T. A., Blazquez, P. M., Chen, A. & Angelaki, D. E. Spatiotemporal properties of optic flow and vestibular tuning in the cerebellar nodulus and uvula. J. Neurosci. 33, 15145–151603 (2013).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen, A., DeAngelis, G. C. & Angelaki, D. E. Macaque parieto-insular vestibular cortex: responses to self-motion and optic flow. J. Neurosci. 30, 3022–3042 (2010).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen, A., Zeng, F., DeAngelis, G. C. & Angelaki, D. E. Dynamics of heading and choice-related signals in the parieto-insular vestibular cortex of macaque monkeys. J. Neurosci. 41, 3254–3265 (2021).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu, B., Tian, Q. & Gu, Y. Robust vestibular self-motion signals in macaque posterior cingulate region. eLife 10, e64569 (2021).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bremmer, F., Kubischik, M., Pekel, M., Lappe, M. & Hoffmann, K. P. Linear vestibular self-motion signals in monkey medial superior temporal area. Ann. N. Y. Acad. Sci. 871, 272–281 (1999).

Article  CAS  PubMed  Google Scholar 

Duffy, C. J. MST neurons respond to optic flow and translational movement. J. Neurophysiol. 80, 1816–1827 (1998).

Article  CAS  PubMed  Google Scholar 

Gu, Y., Watkins, P. V., Angelaki, D. E. & DeAngelis, G. C. Visual and nonvisual contributions to three-dimensional heading selectivity in the medial superior temporal area. J. Neurosci. 26, 73–85 (2006).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sasaki, R., Angelaki, D. E. & DeAngelis, G. C. Processing of object motion and self-motion in the lateral subdivision of the medial superior temporal area in macaques. J. Neurophysiol. 121, 1207–1221 (2019).

Article  PubMed  PubMed Central  Google Scholar 

Bremmer, F., Klam, F., Duhamel, J. R., Ben Hamed, S. & Graf, W. Visual–vestibular interactive responses in the macaque ventral intraparietal area (VIP). Eur. J. Neurosci. 16, 1569–1586 (2002).

Article  PubMed  Google Scholar 

Chen, A., DeAngelis, G. C. & Angelaki, D. E. Representation of vestibular and visual cues to self-motion in ventral intraparietal cortex. J. Neurosci. 31, 12036–12052 (2011).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen, A., Deangelis, G. C. & Angelaki, D. E. Functional specializations of the ventral intraparietal area for multisensory heading discrimination. J. Neurosci. 33, 3567–3581 (2013).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Avila, E., Lakshminarasimhan, K. J., DeAngelis, G. C. & Angelaki, D. E. Visual and vestibular selectivity for self-motion in macaque posterior parietal area 7a. Cereb. Cortex 29, 3932–3947 (2019).

Article  PubMed  Google Scholar 

Chen, A., DeAngelis, G. C. & Angelaki, D. E. Convergence of vestibular and visual self-motion signals in an area of the posterior sylvian fissure. J. Neurosci. 31, 11617–11627 (2011).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gu, Y., Cheng, Z., Yang, L., DeAngelis, G. C. & Angelaki, D. E. Multisensory convergence of visual and vestibular heading cues in the pursuit area of the frontal eye field. Cereb. Cortex 26, 3785–3801 (2016).

Article  PubMed  PubMed Central  Google Scholar 

Zhao, B., Zhang, Y. & Chen, A. Encoding of vestibular and optic flow cues to self-motion in the posterior superior temporal polysensory area. J. Physiol. 599, 3937–3954 (2021).

Article  CAS  PubMed  Google Scholar 

Lappe, M., Bremmer, F., Pekel, M., Thiele, A. & Hoffmann, K. P. Optic flow processing in monkey STS: a theoretical and experimental approach. J. Neurosci. 16, 6265–6285 (1996).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gu, Y., Fetsch, C. R., Adeyemo, B., Deangelis, G. C. & Angelaki, D. E. Decoding of MSTd population activity accounts for variations in the precision of heading perception. Neuron 66, 596–609 (2010).

Article 

Comments (0)

No login
gif