The association of intraoperative hyperglycemia and postoperative infectious complications after lung transplantation: a single-center retrospective study

Aguilar-Guisado M, Givaldá J, Ussetti P, Ramos A, Morales P, Blanes M, et al. Pneumonia after lung transplantation in the RESITRA Cohort: a multicenter prospective study. Am J Transplant. 2007;7(8):1989–96.

Article  CAS  PubMed  Google Scholar 

Vriesendorp TM, Morélis QJ, Devries JH, Legemate DA, Hoekstra JBL. Early post-operative glucose levels are an independent risk factor for infection after peripheral vascular surgery A retrospective study. Eur J Vasc Endovasc Surg. 2004;28(5):520–5.

Article  CAS  PubMed  Google Scholar 

Kiran RP, Turina M, Hammel J, Fazio V. The clinical significance of an elevated postoperative glucose value in nondiabetic patients after colorectal surgery: evidence for the need for tight glucose control? Ann Surg. 2013;258(4):599–604.

Article  PubMed  Google Scholar 

Park C, Hsu C, Neelakanta G, Nourmand H, Braunfeld M, Wray C, et al. Severe intraoperative hyperglycemia is independently associated with surgical site infection after liver transplantation. Transplantation. 2009;87(7):1031–6.

Article  PubMed  Google Scholar 

Xiong X, Chen D, Cai S, Qiu L, Shi J. Association of intraoperative hyperglycemia with postoperative composite infection after cardiac surgery with cardiopulmonary bypass: a retrospective cohort study. Front Cardiovasc Med. 2023;9:1060283.

Article  PubMed  PubMed Central  Google Scholar 

Shah NJ, Leis A, Kheterpal S, Englesbe MJ, Kumar SS. Association of intraoperative hyperglycemia and postoperative outcomes in patients undergoing non-cardiac surgery: a multicenter retrospective study. BMC Anesthesiol. 2020;20(1):106.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Oishi H, Okada Y, Sato M, Nakajima J, Nakajima D, Shiraishi T, et al. Prognostic factors for lung transplant recipients focusing on age and gender: the Japanese lung transplantation report 2022. Surg Today. 2023;53(10):1188–98.

Article  PubMed  PubMed Central  Google Scholar 

Hirama T, Akiba M, Ui M, Shibata S, Tomiyama F, Watanabe T, et al. Long-term survival and clinical outcomes of delayed chest closure following lung transplantation. Surg Today. 2024;54(10):1138–45.

Article  PubMed  PubMed Central  Google Scholar 

Aguilar PR, Bemiss BC, Witt C, Byers DE, Kreisel D, Puri V, et al. Impact of delayed chest closure on surgical site infection after lung transplantation. Ann Thorac Surg. 2017;104(4):1208–14.

Article  PubMed  Google Scholar 

Nosotti M, Arsia P, Morlacchi LC. Infections after lung transplantation. J Thorac Dis. 2018;10(6):3849–68.

Article  PubMed  PubMed Central  Google Scholar 

Fernández-Ugidos P, Barge-Caballero E, Gómez-López R, Paniagua-Martin MJ, Barge-Caballero G, Couto-Mallón D, et al. In-hospital postoperative infection after heart transplantation: Risk factors and development of a novel predictive score. Transpl Infect Dis. 2019;21(4):e13104.

Article  PubMed  Google Scholar 

Gao R, Wang W, Qian T, Li X, Yang H, Liu T, et al. Pulmonary bacterial infection after lung transplantation: risk factors and impact on short-term mortality. J Infect. 2024;89(5):106273.

Article  CAS  PubMed  Google Scholar 

Kwon S, Thompson R, Dellinger P, Yanez D, Farrohki E, Flum D. Importance of perioperative glycemic control in general surgery: a report from the Surgical Care and Outcomes Assessment Program. Ann Surg. 2013;257(1):8–14.

Article  PubMed  Google Scholar 

Shuford R, Miller-Ocuin JL. Hyperglycemia in the Perioperative Period. Clin Colon Rectal Surg. 2023;36(3):198–200.

Article  PubMed  PubMed Central  Google Scholar 

Ammori JB, Sigakis M, Englesbe MJ, O’Reilly M, Pelletier SJ. Effect of intraoperative hyperglycemia during liver transplantation. J Surg Res. 2007;140(2):227–33.

Article  CAS  PubMed  Google Scholar 

Shanks AM, Woodrum DT, Kumar SS, Campbell DA Jr, Kheterpal S. Intraoperative hyperglycemia is independently associated with infectious complications after non-cardiac surgery. BMC Anesthesiol. 2018;18(1):90.

Article  PubMed  PubMed Central  Google Scholar 

Kang R, Han S, Lee KW, Kim GS, Choi SJ, Ko JS, et al. Portland intensive insulin therapy during living donor liver transplantation: association with postreperfusion hyperglycemia and clinical outcomes. Sci Rep. 2018;8(1):16306.

Article  PubMed  PubMed Central  Google Scholar 

Li L, Messina JL. Acute insulin resistance following injury. Trends Endocrinol Metab. 2009;20(9):429–35.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Fragoso LVC, Araújo MFM, Lobo LFS, Schreen D, Zanetti ML, Damasceno MMC. Bolus versus continuous insulin infusion in immediate postoperative blood glucose control in liver transplantation: pragmatic clinical trial. Einstein (Sao Paulo). 2022;20:eAO6959.

Article  PubMed  Google Scholar 

Lee H, Kim M, Lee I, Hong C, Jeon J. Impact of hyperglycemia on immune cell function: a comprehensive review. Diabetol Int. 2024;15(4):745–60.

Article  PubMed  Google Scholar 

Jafar N, Edriss H, Nugent K. The effect of short-term hyperglycemia on the innate immune system. Am J Med Sci. 2016;351(2):201–11.

Article  PubMed  Google Scholar 

Xiu F, Stanojcic M, Diao L, Jeschke MG. Stress hyperglycemia, insulin treatment, and innate immune cells. Int J Endocrinol. 2014;2014:486403.

Article  PubMed  PubMed Central  Google Scholar 

Stegenga ME, van der Crabben SN, Blümer RM, Levi M, Meijers JC, Serlie MJ, et al. Hyperglycemia enhances coagulation and reduces neutrophil degranulation, whereas hyperinsulinemia inhibits fibrinolysis during human endotoxemia. Blood. 2008;112(1):82–9.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lazar HL, McDonnell M, Chipkin SR, Furnary AP, Engelman RM, Sadhu AR, et al. The Society of Thoracic Surgeons practice guideline series: blood glucose management during adult cardiac surgery. Ann Thorac Surg. 2009;87(2):663–9.

Article  PubMed  Google Scholar 

Tokuhira N, Uchiyama A, Hoshino T, Kubo N, Ishigaki S, Enokidani Y, et al. Control of blood glucose levels by an artificial pancreas in patients with severe coronavirus disease 2019 pneumonia. Artif Organs. 2023;47(6):990–8.

Article  CAS  PubMed  Google Scholar 

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