Photobiomodulation therapy in the prevention of chemotherapy-induced alopecia in breast cancer patients: a randomized controlled trial

Lukasiewicz S, Czeczelewski M, Forma A, Baj J, Sitarz R, Stanislawek A (2021) Breast Cancer-Epidemiology, risk factors, classification, prognostic markers, and current treatment Strategies-An updated review. Cancers (Basel).;13(17)

Ferlay JEM, Lam F, Laversanne M, Colombet M, Mery L, Piñeros M, Znaor A, Soerjomataram I, Bray F Global Cancer Observatory: Cancer Today 2024 [Available from: https://gco.iarc.fr/today/home

Wang J, Wu SG (2023) Breast cancer: an overview of current therapeutic strategies, challenge, and perspectives. Breast Cancer (Dove Med Press) 15:721–730

CAS  PubMed  Google Scholar 

Waks AG, Winer EP (2019) Breast Cancer treatment: A review. JAMA 321(3):288–300

CAS  PubMed  Google Scholar 

Mosca L, Ilari A, Fazi F, Assaraf YG, Colotti G (2021) Taxanes in cancer treatment: activity, chemoresistance and its overcoming. Drug Resist Updat 54:100742

CAS  PubMed  Google Scholar 

Lai JI, Chao TC, Liu CY, Huang CC, Tseng LM (2022) A systemic review of taxanes and their side effects in metastatic breast cancer. Front Oncol 12:940239

CAS  PubMed  PubMed Central  Google Scholar 

Wikramanayake TC, Haberland NI, Akhundlu A, Laboy Nieves A, Miteva M (2023) Prevention and treatment of Chemotherapy-Induced alopecia: what is available and what is coming?? Curr Oncol 30(4):3609–3626

PubMed  PubMed Central  Google Scholar 

Ozusaglam E, Can G (2021) The impact of the perception of Chemotherapy-Induced alopecia on psychosocial life. Florence Nightingale J Nurs 29(3):361–370

PubMed  PubMed Central  Google Scholar 

Boland V, Brady AM, Drury A (2020) The physical, psychological and social experiences of alopecia among women receiving chemotherapy: an integrative literature review. Eur J Oncol Nurs 49:101840

PubMed  Google Scholar 

Coolbrandt A, T’Jonck A, Blauwens K, Dejaeger E, Neven P, Punie K et al (2021) Scalp cooling in breast cancer patients treated with docetaxel-cyclophosphamide: patient- and nurse-reported results. Breast Cancer Res Treat 186(3):715–722

CAS  PubMed  Google Scholar 

van Alphen K, Versluis A, Dercksen W, de Haas H, Lugtenberg R, Tiemensma J et al (2020) Giving A face to Chemotherapy-Induced alopecia: A feasibility study on drawings by patients. Asia Pac J Oncol Nurs 7(2):218–224

PubMed  PubMed Central  Google Scholar 

Versluis A, van Alphen K, Dercksen W, de Haas H, van den Hurk C, Kaptein AA (2022) Dear hair loss-illness perceptions of female patients with chemotherapy-induced alopecia. Support Care Cancer 30(5):3955–3963

PubMed  Google Scholar 

Gianotti E, Razzini G, Bini M, Crivellaro C, Righi A, Darecchio S et al (2019) Scalp cooling in daily clinical practice for breast Cancer patients undergoing curative chemotherapy: A multicenter interventional study. Asia Pac J Oncol Nurs 6(3):277–282

PubMed  PubMed Central  Google Scholar 

Marks DH, Okhovat JP, Hagigeorges D, Manatis-Lornell AJ, Isakoff SJ, Lacouture ME et al (2019) The effect of scalp cooling on CIA-related quality of life in breast cancer patients: a systematic review. Breast Cancer Res Treat 175(2):267–276

PubMed  Google Scholar 

Crawford M, Mayo T (2024) Scalp cooling success in a black woman. JAAD Case Rep 49:82–84

PubMed  PubMed Central  Google Scholar 

Hamblin MR (2019) Photobiomodulation for the management of alopecia: mechanisms of action, patient selection and perspectives. Clin Cosmet Investig Dermatol 12:669–678

CAS  PubMed  PubMed Central  Google Scholar 

Torres AE, Lim HW (2021) Photobiomodulation for the management of hair loss. Photodermatol Photoimmunol Photomed 37(2):91–98

PubMed  Google Scholar 

Gupta AK, Bamimore MA (2020) Factors influencing the effect of photobiomodulation in the treatment of androgenetic alopecia: A systematic review and analyses of summary-level data. Dermatol Ther 33(6):e14191

PubMed  Google Scholar 

Dodd EM, Winter MA, Hordinsky MK, Sadick NS, Farah RS (2018) Photobiomodulation therapy for androgenetic alopecia: A clinician’s guide to home-use devices cleared by the federal drug administration. J Cosmet Laser Ther 20(3):159–167

PubMed  Google Scholar 

Palma LF, Campos L, Alvares CMA, Serrano RV, de Moraes LOC (2023) Photobiomodulation with a continuous wave red laser (660 nm) as monotherapy for adult alopecia areata: A case presentation. J Lasers Med Sci 14:e21

PubMed  PubMed Central  Google Scholar 

Wikramanayake TC, Villasante AC, Mauro LM, Nouri K, Schachner LA, Perez CI et al (2013) Low-level laser treatment accelerated hair regrowth in a rat model of chemotherapy-induced alopecia (CIA). Lasers Med Sci 28(3):701–706

PubMed  Google Scholar 

Lodewijckx J, Robijns J, Claes M, Pierson M, Lenaerts M, Mebis J (2023) The use of photobiomodulation therapy for the management of chemotherapy-induced alopecia: a randomized, controlled trial (HAIRLASER trial). Support Care Cancer 31(5):269

PubMed  Google Scholar 

Paxman P Pioneers in Scalp Cooling 2022 [Available from: https://paxmanscalpcooling.com/

Chen AP, Setser A, Anadkat MJ, Cotliar J, Olsen EA, Garden BC et al (2012) Grading dermatologic adverse events of cancer treatments: the common terminology criteria for adverse events version 4.0. J Am Acad Dermatol 67(5):1025–1039

PubMed  Google Scholar 

Aaronson NK, Ahmedzai S, Bergman B, Bullinger M, Cull A, Duez NJ et al (1993) The European organization for research and treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. J Natl Cancer Inst 85(5):365–376

CAS  PubMed  Google Scholar 

Sprangers MA, Groenvold M, Arraras JI, Franklin J, te Velde A, Muller M et al (1996) The European organization for research and treatment of Cancer breast cancer-specific quality-of-life questionnaire module: first results from a three-country field study. J Clin Oncol 14(10):2756–2768

CAS  PubMed  Google Scholar 

Cigler T, Isseroff D, Fiederlein B, Schneider S, Chuang E, Vahdat L et al (2015) Efficacy of scalp cooling in preventing chemotherapy-Induced alopecia in breast Cancer patients receiving adjuvant docetaxel and cyclophosphamide chemotherapy. Clin Breast Cancer 15(5):332–334

CAS  PubMed  Google Scholar 

van den Hurk CJ, Peerbooms M, van de Poll-Franse LV, Nortier JW, Coebergh JW, Breed WP (2012) Scalp cooling for hair preservation and associated characteristics in 1411 chemotherapy patients - results of the Dutch scalp cooling registry. Acta Oncol 51(4):497–504

PubMed  Google Scholar 

Zhang XY, Yang KL, Liu WQ, Huang J, Ning N, Effectiveness (2022) Safety, and tolerance of scalp cooling for Chemotherapy-Induced alopecia. Oncol Nurs Forum 49(4):369–384

PubMed  Google Scholar 

Komen MM, Smorenburg CH, van den Hurk CJ, Nortier JW (2013) Factors influencing the effectiveness of scalp cooling in the prevention of chemotherapy-induced alopecia. Oncologist 18(7):885–891

PubMed  PubMed Central  Google Scholar 

Chan J, Adderley H, Alameddine M, Armstrong A, Arundell D, Fox R et al (2021) Permanent hair loss associated with taxane chemotherapy use in breast cancer: A retrospective survey at two tertiary UK cancer centres. Eur J Cancer Care (Engl) 30(3):e13395

PubMed  Google Scholar 

Whalen GF, Ferrans CE (2001) Quality of life as an outcome in clinical trials and cancer care: a primer for surgeons. J Surg Oncol 77(4):270–276

CAS  PubMed  Google Scholar 

King M (2014) Tackling the quality of life conundrum. Asia Pac J Clin Oncol 10(2):99–100

PubMed  Google Scholar 

McClimans L, Browne JP (2012) Quality of life is a process not an outcome. Theor Med Bioeth 33(4):279–292

PubMed  Google Scholar 

Chinmoyee Deori NB (2023) The phenomenon of placebo effect in psychotherapy: a study. PARIPEX INDIAN JOURNAL OF RESEARCH, pp 89–91

de Medeiros Quirino L, da Silva Mendonca TM, Martins da Silva CH (2024) Borges Martins Da Silva Paro H. Impact of photobiomodulation on the quality of life of men and women with androgenetic alopecia. Cureus 16(8):e66023

PubMed  PubMed Central  Google Scholar 

Ramasubbu SK, Pasricha RK, Nath UK, Rawat VS, Das B (2021) Quality of life and factors affecting it in adult cancer patients undergoing cancer chemotherapy in a tertiary care hospital. Cancer Rep (Hoboken) 4(2):e1312

PubMed  Google Scholar 

Chen H, Shi X, Liu N, Jiang Z, Ma C, Luo G et al (2024) Photobiomodulation therapy mitigates depressive-like behaviors by remodeling synaptic links and mitochondrial function. J Photochem Photobiol B 258:112998

CAS  PubMed  Google Scholar 

Maiello M, Losiewicz OM, Bui E, Spera V, Hamblin MR, Marques L et al (2019) Transcranial photobiomodulation with Near-Infrared light for generalized anxiety disorder: A pilot study. Photobiomodul Photomed Laser Surg 37(10):644–650

PubMed  PubMed Central  Google Scholar 

Comments (0)

No login
gif