Sitagliptin, diabetes mellitus, and heart failure: an in-depth review of sitagliptin therapy and heart failure in patients with diabetes mellitus

Horlyck-Romanovsky MF, Sumner AE. Treating T2DM by ensuring insulin access is a global challenge. Nat Rev Endocrinol. 2019;15(3):135–7.

Article  CAS  PubMed  Google Scholar 

Joshua SR, Abbas W, Lee J-H. M-Healthcare model: an architecture for a type 2 diabetes mellitus mobile application. Appl Sci. 2023;13(1):8.

Article  CAS  Google Scholar 

Fralick M, Jenkins AJ, Khunti K, Mbanya JC, Mohan V, Schmidt MI. Global accessibility of therapeutics for diabetes mellitus. Nat Rev Endocrinol. 2022;18(4):199–204.

Article  PubMed  PubMed Central  Google Scholar 

Ramzan S, Timmins P, Hasan SS, Babar ZUD. Cost analysis of type 2 diabetes mellitus treatment in economically developed countries. Expert Rev Pharmacoeconomics Outcomes Res. 2019;19(1):5–14.

Article  Google Scholar 

Sahay R, Bantwal G, Chowdhary S. Role of linagliptin in type 2 diabetes mellitus therapy: an indian perspective. Indian J Clin Prac. 2023;34(7):10–20.

Article  Google Scholar 

Gomes MB, Rathmann W, Charbonnel B, Khunti K, Kosiborod M, Nicolucci A, et al. Treatment of type 2 diabetes mellitus worldwide: baseline patient characteristics in the global DISCOVER study. Diabetes Res Clin Pract. 2019;151:20–32.

Article  PubMed  Google Scholar 

Lee S, Lee H, Kim Y, Kim E. Effect of DPP-IV inhibitors on glycemic variability in patients with T2DM: a systematic review and meta-analysis. Sci Rep. 2019;9(1):1–8.

Google Scholar 

Ferguson D, Finck BN. Emerging therapeutic approaches for the treatment of NAFLD and type 2 diabetes mellitus. Nat Rev Endocrinol. 2021;17(8):484–95.

Article  PubMed  PubMed Central  Google Scholar 

Schmidt AM. Diabetes mellitus and cardiovascular disease: Emerging therapeutic approaches. Arterioscler Thromb Vasc Biol. 2019;39(4):558–68.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Subbarayan S, Kipnes MJ. Sitagliptin: a review. Expert Opinion On pharmacotherapy. 2011;12(10):1613–22.

Article  CAS  PubMed  Google Scholar 

Gallwitz BJVh. Review of sitagliptin phosphate: a novel treatment for type 2 diabetes. Vascular Health Risk Manag. 2007;3(2):203.

Article  CAS  Google Scholar 

Dhillon S. Sitagliptin: a review of its use in the management of type 2 diabetes mellitus. Drugs. 2010;70(4):489–512.

Article  CAS  PubMed  Google Scholar 

Scott LJ. Sitagliptin: a review in type 2 diabetes. Drugs. 2017;77(2):209–24.

Article  CAS  PubMed  Google Scholar 

Hansen KB, Hsiao Y, Xu F, Rivera N, Clausen A, Kubryk M, et al. Highly efficient asymmetric synthesis of sitagliptin. J Am Chem Soc. 2009;131(25):8798–804.

Article  CAS  PubMed  Google Scholar 

Lyseng-Williamson KA. Sitagliptin Drugs. 2007;67(4):587–97.

Article  CAS  PubMed  Google Scholar 

Plosker GL. Sitagliptin: a review of its use in patients with type 2 diabetes mellitus. Drugs. 2014;74(2):223–42.

Article  CAS  PubMed  Google Scholar 

Engel SS, Round E, Golm GT, Kaufman KD, Goldstein BJ. Safety and tolerability of sitagliptin in type 2 diabetes: pooled analysis of 25 clinical studies. Diabetes Therapy. 2013;4(1):119–45.

Article  PubMed  PubMed Central  Google Scholar 

Green JB, Bethel MA, Armstrong PW, Buse JB, Engel SS, Garg J, et al. Effect of sitagliptin on cardiovascular outcomes in type 2 diabetes. N Engl J Med. 2015;373(3):232–42.

Article  CAS  PubMed  Google Scholar 

Rossignol P, Hernandez AF, Solomon SD, Zannad F. Heart failure drug treatment. Lancet. 2019;393(10175):1034–44.

Article  CAS  PubMed  Google Scholar 

Tomasoni D, Adamo M, Lombardi CM, Metra M. Highlights in heart failure. ESC Heart Failure. 2019;6(6):1105–27.

Article  PubMed  Google Scholar 

Sotoudeheian M, Hoseini S, Mirahmadi S-M-S. Understanding the Pathophysiology of Heart Failure with Mid-Range Ejection Fraction: A Comprehensive Narrative Review. Preprints: Preprints; 2023.

Sotoudeheian M, Soleimani M, Farahmandian N. Molecular Pathways Disturbances during COVID-19 Lead to Cardiomyocyte Necroptosis. Preprints. 2023.

Ziaeian B, Fonarow GC. Epidemiology and aetiology of heart failure. Nat Rev Cardiol. 2016;13(6):368–78.

Article  PubMed  PubMed Central  Google Scholar 

Adamo L, Rocha-Resende C, Prabhu SD, Mann DL. Reappraising the role of inflammation in heart failure. Nat Rev Cardiol. 2020;17(5):269–85.

Article  PubMed  Google Scholar 

Giannitsi S, Maria B, Bechlioulis A, Naka K. Endothelial dysfunction and heart failure: a review of the existing bibliography with emphasis on flow mediated dilation. JRSM Cardiovasc Dis. 2019;8:2048004019843047.

Article  PubMed  PubMed Central  Google Scholar 

Pecini R, Møller DV, Torp-Pedersen C, Hassager C, Køber L. Heart failure etiology impacts survival of patients with heart failure. Int J Cardiol. 2011;149(2):211–5.

Article  PubMed  Google Scholar 

Groenewegen A, Rutten FH, Mosterd A, Hoes AW. Epidemiology of heart failure. Eur J Heart Fail. 2020;22(8):1342–56.

Article  PubMed  Google Scholar 

Seferović PM, Vardas P, Jankowska EA, Maggioni AP, Timmis A, Milinković I, et al. The heart failure association atlas: heart failure epidemiology and management statistics 2019. Eur J Heart Fail. 2021;23(6):906–14.

Article  PubMed  Google Scholar 

de Boer RA, Yu L, van Veldhuisen DJ. Galectin-3 in cardiac remodeling and heart failure. Curr Heart Fail Rep. 2010;7:1–8.

Article  PubMed  PubMed Central  Google Scholar 

Gehlken C, Suthahar N, Meijers WC, de Boer RA. Galectin-3 in heart failure: an update of the last 3 years. Heart Fail Clin. 2018;14(1):75–92.

Article  PubMed  Google Scholar 

Zaborska B, Sikora-Frąc M, Smarż K, Pilichowska-Paszkiet E, Budaj A, Sitkiewicz D, et al. The role of galectin-3 in heart failure—the diagnostic, prognostic and therapeutic potential—where do we stand? Int J Mol Sci. 2023;24(17):13111.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sotoudeheian M. LBPS 02–05 atrial fibrillation immunological determinants: role of galectin-3. J Hypertens. 2016;34: e507.

Article  Google Scholar 

Mohtasham Kia Y, Cannavo A, Bahiraie P, Alilou S, Saeedian B, Babajani N, et al. Insights into the role of galectin-3 as a diagnostic and prognostic biomarker of atrial fibrillation. Disease Markers. 2023. https://doi.org/10.1155/2023/2097012.

Article  PubMed  PubMed Central  Google Scholar 

Sotoudeheian MJ, Mirahmadi SMS, Pirhayati M, Azarbad R, Nematollahi S, Taghizadeh M, et al. Understanding the role of galectin-1 in heart failure: a comprehensive narrative review. Curr Cardiol Rev. 2024;20(1):82–90.

Article  Google Scholar 

Gholaminejad A, Zare N, Dana N, Shafie D, Mani A, Javanmard SH. A meta-analysis of microRNA expression profiling studies in heart failure. Heart Fail Rev. 2021;26:997–1021.

Article  CAS  PubMed  Google Scholar 

Gorjipour F, Dehaki MG, Totonchi Z, Hajimiresmaiel SJ, Azarfarin R, Pazoki-Toroudi H, et al. Inflammatory cytokine response and cardiac troponin I changes in cardiopulmonary bypass using two cardioplegia solutions; del Nido and modified St. Thomas’: a randomized controlled trial. Perfusion. 2017;32(5):394–402.

Article  PubMed 

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