Chiu HY, Chou KT, Su KC, Lin FC, Liu YY, Shiao TH, et al. Obstructive sleep apnea in young Asian adults with sleep-related complaints. Sci Rep. 2022;12:20582.
Article CAS PubMed PubMed Central Google Scholar
Snyder B, Cunningham RL. Sex differences in sleep apnea and comorbid neurodegenerative diseases. Steroids. 2018;133:28–33.
Article CAS PubMed Google Scholar
Guay-Gagnon M, Vat S, Forget MF, Tremblay-Gravel M, Ducharme S, Nguyen QD, et al. Sleep apnea and the risk of dementia: a systematic review and meta-analysis. J Sleep Res. 2022;31:e13589.
Lee JE, Yang SW, Ju YJ, Ki SK, Chun KH. Sleep-disordered breathing and Alzheimer’s disease: a nationwide cohort study. Psychiatry Res. 2019;273:624–30.
Park JE, Kim BS, Kim KW, Hahm BJ, Sohn JH, Suk HW, et al. Decline in the incidence of all-cause and Alzheimer’s Disease Dementia: a 12-Year-later rural cohort study in Korea. J Korean Med Sci. 2019;34:e293.
Article PubMed PubMed Central Google Scholar
Neo WL, Ng ACW, Rangabashyam M, Hao Y, Ho KL, Senin SRB, et al. Prevalence of Cardiac arrhythmias in Asian patients with obstructive sleep apnea: a Singapore Sleep Center Experience. J Clin Sleep Med. 2017;13:1265–71.
Article PubMed PubMed Central Google Scholar
Brady EM, Davies MJ, Hall AP, Talbot DC, Dick JL, Khunti K. An investigation into the relationship between sleep-disordered breathing, the metabolic syndrome, cardiovascular risk profiles, and inflammation between South asians and caucasians residing in the United Kingdom. Metab Syndr Relat Disord. 2012;10:152–8.
Article CAS PubMed Google Scholar
Leong WB, Arora T, Jenkinson D, Thomas A, Punamiya V, Banerjee D, et al. The prevalence and severity of obstructive sleep apnea in severe obesity: the impact of ethnicity. J Clin Sleep Med. 2013;9:853–8.
Article PubMed PubMed Central Google Scholar
Cao Q, Tan CC, Xu W, Hu H, Cao XP, Dong Q, et al. The prevalence of dementia: a systematic review and Meta-analysis. J Alzheimers Dis. 2020;73:1157–66.
Kim SE, Lee JS, Woo S, Kim S, Kim HJ, Park S, et al. Sex-specific relationship of cardiometabolic syndrome with lower cortical thickness. Neurology. 2019;93:e1045–57.
Article CAS PubMed PubMed Central Google Scholar
Kang SH, Liu M, Park G, Kim SY, Lee H, Matloff W, et al. Different effects of cardiometabolic syndrome on brain age in relation to gender and ethnicity. Alzheimers Res Ther. 2023;15:68.
Article PubMed PubMed Central Google Scholar
Gray EL, McKenzie DK, Eckert DJ. Obstructive sleep apnea without obesity is common and difficult to treat: evidence for a distinct pathophysiological phenotype. J Clin Sleep Med. 2017;13:81–8.
Article PubMed PubMed Central Google Scholar
Antonaglia C, Passuti G. Obstructive sleep apnea syndrome in non-obese patients. Sleep Breath. 2022;26:513–8.
Wong Zhang DE, Tran V, Vinh A, Dinh QN, Drummond GR, Sobey CG, et al. Pathophysiological Links between Obesity and dementia. Neuromolecular Med. 2023;25:451–6.
Article CAS PubMed PubMed Central Google Scholar
Appropriate body-mass. Index for Asian populations and its implications for policy and intervention strategies. Lancet. 2004;363:157–63.
SCHOENFELD D. Partial residuals for the proportional hazards regression model. Biometrika. 1982;69:239–41.
Li M, Sun Z, Sun H, Zhao G, Leng B, Shen T, et al. Paroxysmal slow wave events are associated with cognitive impairment in patients with obstructive sleep apnea. Alzheimers Res Ther. 2022;14:200.
Article CAS PubMed PubMed Central Google Scholar
Baril AA, Carrier J, Lafrenière A, Warby S, Poirier J, Osorio RS, et al. Biomarkers of dementia in obstructive sleep apnea. Sleep Med Rev. 2018;42:139–48.
Article PubMed PubMed Central Google Scholar
Kazim SF, Sharma A, Saroja SR, Seo JH, Larson CS, Ramakrishnan A, et al. Chronic intermittent hypoxia enhances pathological tau seeding, propagation, and Accumulation and exacerbates Alzheimer-like memory and synaptic plasticity deficits and molecular signatures. Biol Psychiatry. 2022;91:346–58.
Article CAS PubMed Google Scholar
May AM, Mehra R. Obstructive sleep apnea: role of intermittent hypoxia and inflammation. Semin Respir Crit Care Med. 2014;35:531–44.
Lal C, Strange C, Bachman D. Neurocognitive impairment in obstructive sleep apnea. Chest. 2012;141:1601–10.
de la Torre JC. Cerebromicrovascular pathology in Alzheimer’s disease compared to normal aging. Gerontology. 1997;43:26–43.
Buratti L, Viticchi G, Falsetti L, Cagnetti C, Luzzi S, Bartolini M, et al. Vascular impairment in Alzheimer’s disease: the role of obstructive sleep apnea. J Alzheimers Dis. 2014;38:445–53.
Liguori C, Maestri M, Spanetta M, Placidi F, Bonanni E, Mercuri NB, et al. Sleep-disordered breathing and the risk of Alzheimer’s disease. Sleep Med Rev. 2021;55:101375.
Hablitz LM, Plá V, Giannetto M, Vinitsky HS, Stæger FF, Metcalfe T, et al. Circadian control of brain glymphatic and lymphatic fluid flow. Nat Commun. 2020;11:4411.
Article CAS PubMed PubMed Central Google Scholar
Hablitz LM, Vinitsky HS, Sun Q, Stæger FF, Sigurdsson B, Mortensen KN, et al. Increased glymphatic influx is correlated with high EEG delta power and low heart rate in mice under anesthesia. Sci Adv. 2019;5:eaav5447.
Article CAS PubMed PubMed Central Google Scholar
Xie L, Kang H, Xu Q, Chen MJ, Liao Y, Thiyagarajan M, et al. Sleep drives metabolite clearance from the adult brain. Science. 2013;342:373–7.
Article CAS PubMed Google Scholar
Nedergaard M, Goldman SA. Glymphatic failure as a final common pathway to dementia. Science. 2020;370:50–6.
Article CAS PubMed PubMed Central Google Scholar
Eide PK, Vinje V, Pripp AH, Mardal KA, Ringstad G. Sleep deprivation impairs molecular clearance from the human brain. Brain. 2021;144:863–74.
Siow TY, Toh CH, Hsu JL, Liu GH, Lee SH, Chen NH, et al. Association of Sleep, Neuropsychological Performance, and Gray Matter volume with glymphatic function in Community-Dwelling older adults. Neurology. 2022;98:e829–38.
Ooms S, Overeem S, Besse K, Rikkert MO, Verbeek M, Claassen JA. Effect of 1 night of total sleep deprivation on cerebrospinal fluid β-amyloid 42 in healthy middle-aged men: a randomized clinical trial. JAMA Neurol. 2014;71:971–7.
Sprecher KE, Bendlin BB, Racine AM, Okonkwo OC, Christian BT, Koscik RL, et al. Amyloid burden is associated with self-reported sleep in nondemented late middle-aged adults. Neurobiol Aging. 2015;36:2568–76.
Comments (0)