Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, et al. The third international consensus definitions for sepsis and septic shock (Sepsis-3). JAMA. 2016;315:801–10.
Article CAS PubMed Central Google Scholar
Sterne JAC, Savović J, Page MJ, Elbers RG, Blencowe NS, Boutron I, et al. RoB 2: a revised tool for assessing risk of bias in randomised trials. BMJ. 2019;366:l4898.
Sterne JA, Hernán MA, Reeves BC, Savović J, Berkman ND, Viswanathan M, et al. ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions. BMJ. 2016;355:i4919.
Article PubMed Central Google Scholar
Bone RC, Balk RA, Cerra FB, et al. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. Chest. 1992;101:1644–55.
Levy MM, Fink MP, Marshall JC, Abraham E, Angus D, Cook D, Cohen J, Opal SM, Vincent JL, Ramsay G. 2001 SCCM/ESICM/ACCP/ATS/SIS international sepsis definitions conference. Intensive Care Med. 2003;29:530–8.
Vincent JL, Opal SM, Marshall JC, Tracey KJ. Sepsis definitions: time for change. Lancet. 2013;381:774–5.
Article PubMed Central Google Scholar
Pittet D, Rangel-Frausto S, Li N, Tarara D, Costigan M, Rempe L, Jebson P, Wenzel RP. Systemic inflammatory response syndrome, sepsis, severe sepsis and septic shock: incidence, morbidities and outcomes in surgical ICU patients. Intensive Care Med. 1995;21:302–9.
Egi M, Ogura H, Yatabe T. The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020). J Intensive Care. 2021;9:53.
Article PubMed Central Google Scholar
Egi M, Ogura H, Yatabe T. The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020). Acute Med Surg. 2021;8: e659.
Article PubMed Central Google Scholar
Vincent JL, Moreno R, Takala J. The SOFA (sepsis-related organ failure assessment) score to describe organ dysfunction/failure: On behalf of the working group on sepsis-related problems of the European society of intensive care medicine. Intensive Care Med. 1996;22:707–10.
Peake SL, Delaney A, Bailey M. Potential impact of the 2016 consensus definitions of sepsis and septic shock on future sepsis research. Ann Emerg Med. 2017;70:553–61.
Maitra S, Som A, Bhattacharjee S. Accuracy of quick sequential organ failure assessment (qSOFA) score and systemic inflammatory response syndrome (SIRS) criteria for predicting mortality in hospitalized patients with suspected infection: a meta-analysis of observational studies. Clin Microbiol Infect. 2018;24:1123–9.
Song JU, Sin CK, Park HK. Performance of the quick sequential (sepsis-related) organ failure assessment score as a prognostic tool in infected patients outside the intensive care unit: a systematic review and meta-analysis. Crit Care. 2018;22:28.
Article PubMed Central Google Scholar
Moreno R, Rhodes A, Piquilloud L. The sequential organ failure assessment (SOFA) score: has the time come for an update? Crit Care. 2023;27:15.
Article PubMed Central Google Scholar
IDSA Sepsis Task Force. Infectious Diseases Society of America (IDSA) position statement: why IDSA did not endorse the surviving sepsis campaign guidelines. Clin Infect Dis. 2018;66:1631–5.
Kaukonen KM, Bailey M, Pilcher D. Systemic inflammatory response syndrome criteria in defining severe sepsis. N Engl J Med. 2015;372:1629–38.
Seymour CW, Liu VX, Iwashyna TJ. Assessment of clinical criteria for sepsis: for the third international consensus definitions for sepsis and septic shock (Sepsis-3). JAMA. 2016;315:762–74.
Article CAS PubMed Central Google Scholar
Royal College of Physicians. National Early Warning Score (NEWS) 2. https://www.rcplondon.ac.uk/projects/outputs/national-early-warning-score-news-2. Accessed 13 Feb 2025.
Wang C, Xu R, Zeng Y. A comparison of qSOFA, SIRS and NEWS in predicting the accuracy of mortality in patients with suspected sepsis: a meta-analysis. PLoS ONE. 2022;17: e0266755.
Article CAS PubMed Central Google Scholar
Parshuram CS, Dryden-Palmer K, Farrell C, Canadian Critical Care Trials Group, the EPOCH Investigators. Effect of a pediatric early warning system on all-cause mortality in hospitalized pediatric patients: the EPOCH randomized clinical trial. JAMA. 2018;319:1002–12.
Article PubMed Central Google Scholar
van Nassau SC, van Beek RH, Driessen GJ. Translating sepsis-3 criteria in children: prognostic accuracy of age-adjusted quick SOFA score in children visiting the emergency department with suspected bacterial infection. Front Pediatr. 2018;6:266.
Article PubMed Central Google Scholar
Fabre V, Sharara SL, Salinas AB. Does this patient need blood cultures? A scoping review of indications for blood cultures in adult nonneutropenic inpatients. Clin Infect Dis. 2020;71:1339–47.
Coburn B, Morris AM, Tomlinson G. Does this adult patient with suspected bacteremia require blood culture? JAMA. 2012;308:502–11.
Cheng MP, Stenstrom R, Paquette K. FABLED Investigators: blood culture results before and after antimicrobial administration in patients with severe manifestations of Sepsis: a diagnostic study. Ann Intern Med. 2019;171:547–54.
Cockerill FR, Wilson JW, Vetter EA. Optimal testing parameters for blood cultures. Clin Infect Dis. 2004;38:1724–30.
Lee A, Mirrett S, Reller LB. Detection of bloodstream infections in adults: how many blood cultures are needed? J Clin Microbiol. 2007;45:3546–8.
Article PubMed Central Google Scholar
Doern GV, Carroll KC, Diekema DJ. Practical guidance for clinical microbiology laboratories: a comprehensive update on the problem of blood culture contamination and a discussion of methods for addressing the problem. Clin Microbiol Rev. 2019;33:e00009-e00019.
Article PubMed Central Google Scholar
Metlay JP, Waterer GW, Long AC. Diagnosis and treatment of adults with community-acquired pneumonia. An official clinical practice guideline of the American thoracic society and infectious diseases society of America. Am J Respir Crit Care Med. 2019;200:e45-67.
Article PubMed Central Google Scholar
Kalil AC, Metersky ML, Klompas M. Management of adults with hospital-acquired and ventilator-associated pneumonia: 2016 clinical practice guidelines by the infectious diseases society of America and the American thoracic society. Clin Infect Dis. 2016;63:e61-111.
Article PubMed Central Google Scholar
Torres A, Niederman MS, Chastre J. International ERS/ESICM/ESCMID/ALAT guidelines for the management of hospital-acquired pneumonia and ventilator-associated pneumonia. Eur Respir J. 2017;50:1700582.
Bodilsen J, Dalager-Pedersen M, Schønheyder HC. Time to antibiotic therapy and outcome in bacterial meningitis: a Danish population-based cohort study. BMC Infect Dis. 2016;16:392.
Article PubMed Central Google Scholar
McGill F, Heyderman RS, Panagiotou S. Acute bacterial meningitis in adults. Lancet. 2016;388:3036–47.
Bijlsma MW, Brouwer MC, Kasanmoentalib ES. Community-acquired bacterial meningitis in adults in the Netherlands, 2006–14: a prospective cohort study. Lancet Infect Dis. 2016;16:339–47.
Tan M, Lu Y, Jiang H, Zhang L. The diagnostic accuracy of procalcitonin and C-reactive protein for sepsis: a systematic review and meta-analysis. J Cell Biochem. 2019;120:5852–9.
Liu Y, Hou JH, Li Q. Biomarkers for diagnosis of sepsis in patients with systemic inflammatory response syndrome: a systematic review and meta-analysis. Springerplus. 2016;5:2091.
Article PubMed Central Google Scholar
Kondo Y, Umemura Y, Hayashida K. Diagnostic value of procalcitonin and presepsin for sepsis in critically ill adult patients: a systematic review and meta-analysis. J Intensive Care. 2019;7:22.
Article PubMed Central Google Scholar
Wu CC, Lan HM, Han ST. Comparison of diagnostic accuracy in sepsis between presepsin, procalcitonin, and C-reactive protein: a systematic review and meta-analysis. Ann Intensive Care. 2017;7:91.
Article PubMed Central Google Scholar
Ma L, Zhang H, Yin YL. Role of interleukin-6 to differentiate sepsis from non-infectious systemic inflammatory response syndrome. Cytokine. 2016;88:126–35.
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