Olff M, Frijling JL, Kubzansky LD, Bradley B, Ellenbogen MA, Cardoso C, et al. The role of oxytocin in social bonding, stress regulation and mental health: an update on the moderating effects of context and interindividual differences. Psychoneuroendocrinology. 2013;38(9):1883–94.
Article CAS PubMed Google Scholar
Jurek B, Neumann ID. The oxytocin receptor: from intracellular signaling to behavior. Physiol Rev. 2018;98(3):1805–908.
Article CAS PubMed Google Scholar
Clarke L, Zyga O, Pineo-Cavanaugh PL, Jeng M, Fischbein NJ, Partap S, et al. Socio-behavioral dysfunction in disorders of hypothalamic-pituitary involvement: the potential role of disease-induced oxytocin and vasopressin signaling deficits. Neurosci Biobehav Rev. 2022;140:104770.
Article CAS PubMed PubMed Central Google Scholar
Parker KJ, Garner JP, Libove RA, Hyde SA, Hornbeak KB, Carson DS, et al. Plasma oxytocin concentrations and OXTR polymorphisms predict social impairments in children with and without autism spectrum disorder. Proc Natl Acad Sci USA. 2014;111(33):12258–63.
Article CAS PubMed PubMed Central Google Scholar
Ayaz AB, Karkucak M, Ayaz M, Gokce S, Kayan E, Güler EE, et al. Oxytocin system social function impacts in children with attention-deficit/hyperactivity disorder. Am J Med Genet B Neuropsychiatr Genet. 2015;168(7):609–16.
Article CAS PubMed Google Scholar
Barchi-Ferreira AM, Osório FL. Associations between oxytocin and empathy in humans: a systematic literature review. Psychoneuroendocrinology. 2021;129:105268.
Article CAS PubMed Google Scholar
Pohl TT, Young LJ, Bosch OJ. Lost connections: Oxytocin and the neural, physiological, and behavioral consequences of disrupted relationships. Int J Psychophysiol. 2019;136:54–63.
Kohlhoff J, Cibralic S, Hawes DJ, Eapen V. Oxytocin receptor gene (OXTR) polymorphisms and social, emotional and behavioral functioning in children and adolescents: a systematic narrative review. Neurosci Biobehavioral Reviews. 2022;135:104573.
de Oliveira Pereira Ribeiro L, Vargas-Pinilla P, Kappel DB, Longo D, Ranzan J, Becker MM, et al. Evidence for association between OXTR Gene and ASD clinical phenotypes. J Mol Neurosci. 2018;65(2):213–21.
Waller R, Corral-Frías NS, Vannucci B, Bogdan R, Knodt AR, Hariri AR, et al. An oxytocin receptor polymorphism predicts amygdala reactivity and antisocial behavior in men. Soc Cogn Affect Neurosci. 2016;11(8):1218–26.
Article PubMed PubMed Central Google Scholar
Wu N, Li Z, Su Y. The association between oxytocin receptor gene polymorphism (OXTR) and trait empathy. J Affect Disord. 2012;138(3):468–72.
Article CAS PubMed Google Scholar
Kalyoncu T, Özbaran B, Köse S, Onay H. Variation in the oxytocin receptor gene is associated with social cognition and ADHD. J Atten Disord. 2019;23(7):702–11.
Francis SM, Kim SJ, Kistner-Griffin E, Guter S, Cook EH, Jacob S. ASD and Genetic associations with receptors for oxytocin and Vasopressin-AVPR1A, AVPR1B, and OXTR. Front Neurosci. 2016;10:516.
Article PubMed PubMed Central Google Scholar
LoParo D, Waldman ID. The oxytocin receptor gene (OXTR) is associated with autism spectrum disorder: a meta-analysis. Mol Psychiatry. 2015;20(5):640–6.
Article CAS PubMed Google Scholar
Meyer M, Jurek B, Alfonso-Prieto M, Ribeiro R, Milenkovic VM, Winter J, et al. Structure-function relationships of the disease-linked A218T oxytocin receptor variant. Mol Psychiatry. 2022;27(2):907–17.
Article CAS PubMed PubMed Central Google Scholar
Ma SL, Tang NLS, Tam CWC, Lui VWC, Lam LCW, Chiu HFK, et al. A PIN1 polymorphism that prevents its suppression by AP4 associates with delayed onset of Alzheimer’s disease. Neurobiol Aging. 2012;33(4):804–13.
Article CAS PubMed Google Scholar
Dadds MR, Moul C, Cauchi A, Dobson-Stone C, Hawes DJ, Brennan J, et al. Polymorphisms in the oxytocin receptor gene are associated with the development of psychopathy. Dev Psychopathol. 2014;26(1):21–31.
Chen Y, Lu R, Zheng H, Xiao R, Feng J, Wang H, et al. The NFKB1 polymorphism (rs4648068) is associated with the cell proliferation and motility in gastric cancer. BMC Gastroenterol. 2015;15:21.
Article PubMed PubMed Central Google Scholar
Albert FW, Kruglyak L. The role of regulatory variation in complex traits and disease. Nat Rev Genet. 2015;16(4):197–212.
Article CAS PubMed Google Scholar
Dadds MR, Moul C, Cauchi A, Dobson-Stone C, Hawes DJ, Brennan J, et al. Methylation of the oxytocin receptor gene and oxytocin blood levels in the development of psychopathy. Dev Psychopathol. 2014;26(1):33–40.
Comments (0)